Clinical trials: Anesthesia, Inhalation
Anesthesia
Different Low-flow Sevoflurane Anesthesia Techniques
After reaching 1 MAC level with 4 lt / min fresh gas flow and 2.5% sevoflurane concentration in the initial stage in 35 patients, anesthesia maintenance will be continued with 0.5 lt / min fresh gas flow and 2 -4% sevoflurane…
- Trial name
- NCT04743193
- Testing
- 2.5 %sevoflurane, 8% sevoflurane low flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli Derince Education and Research Hospital
Surgery-Complications, Anesthesia Complication
Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial
The investigators will conduct a 13,000-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major…
- Conditions
- Surgery-Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia
- Trial name
- THRIVE (NCT05991453)
- Testing
- Anesthetic technique Propofol TIVA, Anesthetic technique inhaled agent
- Where
- 24 sites in United States
- Volunteers
- 13,000 people
- Sponsor
- Washington University School of Medicine
Smoke Inhalation
Electronic Cigarette and Surgery (ECigarSurg)
Since decades, literature has shown that smoking has negative effect on postoperative outcome. Recent systematic review and meta-analysis on clinical impact of smoking and smoking cessation showed that postoperative healing…
- Trial name
- ECigarSurg (NCT03594643)
- Where
- France
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Obstructive Sleep Apnea
Influence of Different Anesthetic Procedures on Sleep Disorder Breathing
Obstructive sleep apnea (OSA) is a common form of sleep disordered breathing characterized by partial or complete upper airway obstructions during sleep. OSA is associated with major comorbidities and perioperative complications.
- Trial name
- NCT03499132
- Testing
- anesthesia
- Where
- Czechia
- Volunteers
- 90 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Anesthesia; Functional
Assessment Through Transcutaneous Brain Oximetry (NIRS) of Two Preoxygenation Techniques
Preoxygenation techniques is currently considered a standard of care, but how they influence cerebral oxygenation remains largely unknown.
- Trial name
- NCT04352049
- Testing
- Preoxygenation
- Where
- 2 sites in Spain
- Volunteers
- 53 people
- Sponsor
- Complexo Hospitalario Universitario de A Coruña
Airway Management
I-scoop vs. C-Mac D-Blade Videolaryngoscope for Airway Management Under Spontaneous Breathing and Analgosedation
The purpose of this clinical trial is to investigate whether the videolaryngoscope i-scoop makes airway management under spontaneous breathing and analgosedation more clinically practicable than the established standard device…
- Trial name
- OWN BREATH 2 (NCT07624162)
- Testing
- Airway management under spontaneous breathing with the i-scoop videolaryngoscope, Airway management under spontaneous breathing with the C-Mac D-Blade videolaryngoscope
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Hannover Medical School
Anesthesia; Reaction
Endotracheal Intubation With Sevoflurane in Surgical Pediatric Patients
Aim of the study is to compare the optimal time needed for successful tracheal intubation with immediate 8% sevoflurane and incremental sevoflurane induction in surgical pediatric patients undergoing adenotonsillectomy without…
- Trial name
- NCT02429323
- Testing
- Sevoflurane
- Volunteers
- 100 people
- Sponsor
- University of Sulaimani
Anesthesia
Ambu AuraGain and Teleflex LMA Protector Fiberoptic Assessments in Elective Patients
Participant is being asked to take part in this study because participant is going to have surgery that requires general anesthesia (in which participant is unconscious for the procedure).
- Trial name
- NCT02724956
- Testing
- Ambu AuraGain, Teleflex LMA Protector, Ambu aScope
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Xenon, Sevoflurane
A Pre- and Post- Coronary Artery Bypass Graft Implantation Disposed Application of Xenon
The aim of this study is to determine whether xenon - as compared to sevoflurane - can be applied safely in patients for general anesthesia before and after CABG implantation.
- Conditions
- Xenon, Sevoflurane, Anesthetics, Inhalation, Coronary Disease
- Trial name
- CArDiAX (NCT01285271)
- Testing
- Xenon, Sevoflurane
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- RWTH Aachen University
VENTILATION, Capnography
Effects of Capnometry Monitoring in Post Anesthesia Care Unit
There is few information about the best capnometry value in recovery room for intubated awakening patients. Furthermore, capnometry values could influence ventilation applied by nurses on these patients.
- Trial name
- CAPNOSSPI (NCT03370081)
- Testing
- CAPNOGRAPHY
- Where
- France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Bordeaux
Elective Surgical Procedures, Laparoscopy
Nitrous Oxide Added at the End of Sevoflurane Anesthesia and Recovery
Addition of nitrous oxide N2O towards the end of prolonged isoflurane anesthesia hastens patients recovery. The hypothesis is that the addition of N2O at the end of prolonged sevoflurane anaesthesia also hastens early recovery…
- Conditions
- Elective Surgical Procedures, Laparoscopy, Laparotomy, Anesthesia, General
- Trial name
- SEVONATE (NCT03420586)
- Testing
- Nitrous Oxide
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- General Hospital Zadar
End-stage Chronic Renal Disease, Severe Acute Kidney Failure
Renal Transplantation and Inhaled Anesthetic Sevoflurane (SEVOREIN)
Renal transplantation is characterized by ischemia-reperfusion lesions in allograft. In a previous study, Julier and al. (Anesthesiology 2003) have demonstrated that sevoflurane reduces glomerular lesions in kidney of patients…
- Conditions
- End-stage Chronic Renal Disease, Severe Acute Kidney Failure, Renal Transplantation
- Trial name
- SévoRein (NCT00337051)
- Testing
- Sevoflurane, Propofol
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Bordeaux
Anesthesia, General, Anesthetics Adverse Reaction
Impact of Anesthetic Environment the Sex Ratio of the Children of Female Assistants
The aims of this multi center retrospective study was to determine: whether the sex ratio of the offspring of female assistants in anesthesia-resuscitation differs from that of the population at large whether the assistants' work…
- Trial name
- NCT04532502
- Testing
- Anesthetics, Inhalation
- Where
- Belgium
- Volunteers
- 143 people
- Sponsor
- University of Liege
Analgesia
Evaluation of Surgical Stress Index (SSI) During Sevoflurane/Remifentanil Anesthesia
The aim of the present prospective randomized study was to challenge the ability of SSI to detect painful stimulation during sevoflurane - remifentanil anesthesia.
- Trial name
- NCT00791791
- Testing
- standardized pain stimulus
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University Hospital Schleswig-Holstein
Oropharyngeal Neoplasms
Isocapnic Hyperventilation - an Alternative Method
Isocapnic hyperventilation (IHV) is a method that shortens time to extubation after inhalation anaesthesia by increasing airway carbon dioxide (CO2) during hyperventilation (HV).
- Trial name
- NCT03074110
- Testing
- Isocapnic hyperventilation
- Where
- Sweden
- Volunteers
- 31 people
- Sponsor
- Sahlgrenska University Hospital
Pulmonary Aspiration of Gastric Contents
A Multicentre Preoperative Fasting Audit
The new European Society of Anaesthesiology and Intensive Care (ESAIC) preoperative fasting guideline recommends a one hour minimum fasting time for clear fluids.
- Trial name
- EUROFAST (NCT05519969)
- Where
- Sweden
- Volunteers
- 307,162 people
- Sponsor
- Uppsala University
Pulmonary Aspiration of Gastric Contents
Comparison of Different Preoperative Fasting Times in Pediatric Patients Undergoing Elective General Anaesthesia
Rationale of this study is to provide an evidence on minimal safe clear fluid fasting duration without the risk of aspiration of gastric contents during elective pediatric procedures under general anesthesia.
- Trial name
- NCT05922072
- Testing
- Nasogastric aspiration for measurement of Residual Gastric Volume, Nasogastric Aspiration for Measurement of Gastric pH
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- King Edward Medical University
Intraoperative Awareness
Incidence of Intraoperative Awareness in Indian Patient Population
The profiling of bi-spectral index (BIS) monitored facilitation of general anesthesia (GA), including, anesthesia induction and maintenance of GA depth state, emergence characteristics, and postoperative recovery parameters, is…
- Trial name
- NCT03571945
- Testing
- Bi-spectral Index (BIS QUATRO REF #186-0106), End tidal anaesthesia gas concentration (ETAG)
- Where
- 5 sites in India
- Volunteers
- 2,000 people
- Sponsor
- Sir Ganga Ram Hospital
Respiration, Artificial, Positive-Pressure Respiration
VENtilation Modalities During Transport of PostoperatIve CRITically Ill Patients to the ICU
Patients undergoing major non-cardiac surgery may require postoperative mechanical ventilation and transfer from the operating room to the intensive care unit (ICU).
- Conditions
- Respiration, Artificial, Positive-Pressure Respiration, Postoperative Complications (Cardiopulmonary), Postoperative Complications
- Trial name
- VENTICRIT (NCT07646249)
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva
General Anesthesia Using Endotracheal Intubation
Comparison of Different Inspiratory to Expiratory Ratios on Respiratory Mechanics and Oxygenation in Robot-assisted Laparoscopic Radical Prostatectomy With Steep Trendelenburg Position and Pneumoperitoneum
The steep trendelenburg position and pneumoperitoneum during laparoscopic surgery have the potential to cause an adverse effects on respiratory mechanics and gas exchange.
- Trial name
- NCT01892449
- Testing
- prolonged inspiratory to expiratory (I:E) ratio (1:1), conventional I:E ratio (1:2)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University