Clinical trials: Anesthesia, Local
Local Anesthesia
Effects of Articaine Computer-controlled and Conventional Delivery for Anterior and Middle Superior Alveolar Nerve Block
The purpose of this study was to investigate and compare pulpal anesthesia and cardiovascular parameters obtained with 0.6 ml of 4% articaine with epinephrine (1:100.000) for anterior and middle superior alveolar nerve (AMSA)…
- Trial name
- NCT02440347
- Testing
- Computer controlled anesthetic delivery by Anaeject, Conventional anesthetic delivery by carpule syringe
- Where
- Serbia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Inguinal Hernia, Anesthesia, Local
A Trial of Local Anaesthesia Versus Local Anaesthesia and Conscious Sedation for Hernioplasty
The aim of this RCT is to compare patient outcomes of inguinal hernioplasty under Local Anaesthesia alone versus Local Anaesthesia and Conscious Sedation Specific study objectives are to determine the effect of conscious sedation…
- Conditions
- Inguinal Hernia, Anesthesia, Local, Conscious Sedation
- Trial name
- NCT02444260
- Testing
- Midazolam, Intravenous Normal Saline, Bupivocaine
- Where
- Jamaica
- Volunteers
- 180 people
- Sponsor
- The University of The West Indies
Hip Fractures, Anesthesia Local
Shamrock Versus Lumbar Ultrasound Trident - Ultrasound Guided Block of the Lumbar Plexus
The main objective of the trial is to complete a double-blinded randomized controlled trial of a lumbar plexus block with the Shamrock technique versus the Lumbar Ultrasound Trident technique by estimating the time of performance…
- Conditions
- Hip Fractures, Anesthesia Local, Pain, Postoperative
- Trial name
- NCT02255591
- Testing
- Lidocaine-adrenaline added gadolinium.
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Anesthesia, Local
A Study Investigating Properties of the Transversus Abdominis Plane Block
In this study we investigate the following properties of the transversus abdominis plane block in healthy volunteers: 1. Cutaneous analgesic distribution 2. Muscular affection 3. Reproducibility
- Trial name
- NCT01679392
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Anesthesia, Local
Bupivacaine Supplementation For Postoperative Pain Control In Surgical Removal Of Mandibular Third Molars
Control of postoperative pain is a foremost goal in achieving a satisfactory postoperative recovery. Surgical removal of lower third molars is accompanied by postoperative pain that is at its peak in the first 12 hours.
- Trial name
- NCT02353676
- Testing
- Bupivacaine, SALINE
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cosmozone Dental Clinic
Local Anesthesia of the Skin.
Fractional Laser Assisted Delivery of Anesthetics
The purpose of this study is to assess the efficacy of fractional CO2 laser assisted delivery of topically applied anesthetics (articaine hydrochloride 40 mg/ml and epinephrine 10 μg/ml solution and EMLA cream) regarding to…
- Trial name
- NCT02246179
- Testing
- AFXL, AHES, EMLA cream
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Netherlands Institute for Pigment Disorders
Dental Anesthesia, Anesthesia, Local
Study of OraVerse® for Safety and Efficacy in Pediatric Dental Patients
The purpose of this study is to determine whether OraVerse is safe and effective for the reversal of dental anesthesia in children 2 to 5 years of age weighing at least 10 kg.
- Conditions
- Dental Anesthesia, Anesthesia, Local, Anesthesia, Reversal
- Trial name
- NCT01474382
- Testing
- OraVerse
- Where
- 7 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Novocol Pharmaceutical of Canada, Inc.
Local Anesthesia, Satisfaction
Evaluation of Deep Topical Fornix Nerve Block Versus Topical Anaesthesia Procedure
General anaesthesia now a days is not the first choice in phakic intra ocular lens surgery (Phakic IOL) , the short duration of the surgery, general anaesthesia complications, decrease the length of hospital stay and decreasing…
- Trial name
- NCT02196441
- Testing
- 2% tetracaine local anaesthetic drops, 0.5% bupivacaine
- Where
- Saudi Arabia
- Volunteers
- 102 people
- Sponsor
- Cairo University
Local Anesthesia, Pain, Postoperative
EMLA Topical Anesthetic During Scaling and Root Planing
Injectable anesthesics previous to subgingival scaling and root planing (SRP) presents some disadvantages like fear of the needle insertion, long-lasting effect and prolonged dampening of adjacent tissues.
- Conditions
- Local Anesthesia, Pain, Postoperative, Self-Perception
- Trial name
- NCT01860235
- Testing
- EMLA, Injectable anesthesia, 2% Benzocaine
- Volunteers
- 32 people
- Sponsor
- Franciscan University Center
Local Anesthesia, Intradermal Injections
A Study to Assess the Safety and Efficacy of a Microneedle Device for Local Anesthesia
The purpose of this study is to determine whether the MicronJet microneedle device is effective for inducing rapid and painless local anesthesia prior to insertions of intravenous catheters.
- Trial name
- NCT00539084
- Testing
- MicronJet
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NanoPass Technologies Ltd
Postoperative Pain, Anesthesia, Local
Additional Effect of Wound Infiltration After Cesarean Section With Optimal Standard Analgesia
The purpose of this study is to determine wether wound infiltration brings additional analgesia effect after cesarean section with optimal standard postoperative analgesia
- Conditions
- Postoperative Pain, Anesthesia, Local, Breast Feeding
- Trial name
- KTcesar (NCT01751256)
- Testing
- Continuous wound infiltration
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Poissy-Saint Germain Hospital
Periodontal Diseases, Local Anesthesia
The Anesthetic Effect of Anterior Middle Superior Alveolar Technique
Anesthesia of the soft and hard tissues in the maxilla may require up to five injections. Thus, the aim of the present study was to evaluate the anesthetic efficacy in buccal tissues after the use of the anterior middle superior…
- Conditions
- Periodontal Diseases, Local Anesthesia, Pain
- Trial name
- NCT01742559
- Testing
- Anterior middle superior alveolar, Supraperiosteal technique
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- State University of Maringá
Local Anesthesia
Efficacy and Safety of Lambdalina (Lidocaine Cream) Versus Placebo as an Anesthetic for Laser Hair Removal
Double-blind, randomized, placebo-controlled trial to assess the efficacy of Lambdalina (lidocaine cream) in reducing pain associated with laser hair removal in women.
- Trial name
- NCT01360749
- Testing
- Lambdalina® (Lidocaine 4% cream)
- Where
- 2 sites in Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- ISDIN
Colonic Diseases, Post-operative Pain
Local Anaesthesia Used During Fast-track Colonic Surgery: Evaluation of Bupivacaine and Levobupivacaine in Practice
The standard treatment for post operative pain is now bupivacaine + sufentanil. The use of this combination during fast-track colonic surgery leads frequently to post-operative nausea and vomiting and limited mobilisation…
- Conditions
- Colonic Diseases, Post-operative Pain, Local Anesthesia
- Trial name
- NCT01105442
- Where
- Netherlands
- Volunteers
- 14 people
- Sponsor
- Martini Hospital Groningen
Cesarean Section, Anesthesia, Spinal
Comparison of Standard and Minidose Spinal Anesthesia for Cesarean Section Operation Using Marcaine Spinal 0.5% Heavy
The objectives of this study is to test a combination of low dose local anesthetic Bupivacaine diluted in patient's CSF with lipophilic opiate Fentanyl for optimal spinal anesthesia during Cesarean Section.
- Conditions
- Cesarean Section, Anesthesia, Spinal, Local Anaesthetics Causing Adverse Effects in Therapeutic Use
- Trial name
- NCT01303731
- Testing
- Bupivacaine and Fentanyl, Bupivacaine
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Local Anesthesia
Safety and Efficacy Study of an Iontophoretic Patch Containing Lidocaine and Epinephrine for Venipuncture in Healthy Adult Volunteers
The purpose of this study is to evaluate the effectiveness of administering Lidocaine and Epinephrine using an iontophoretic device treatment to provide local anesthesia to healthy adult volunteer subjects undergoing venipuncture.
- Trial name
- NCT00889642
- Testing
- Iontophoretic Drug Delivery System with Lidocaine/Epinephrine, Iontophoretic Drug Delivery System with Epinephrine
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dharma Therapeutics Inc.
Injuries, Hand, Anesthesia Conduction
Cardiovascular Safety Research: Bupivacaine With Vasoconstrictor Versus Ropivacaine in Brachial Plexus Block
The purpose of this study is to determine if bupivacaine (75% levobupivacaine plus 25% racemic bupivacaine) with vasoconstrictor is effective and safety as ropivacaine in brachial plexus block for orthopedic surgery.
- Conditions
- Injuries, Hand, Anesthesia Conduction, Anesthetics, Local
- Trial name
- NCT00523289
- Testing
- Bupivacaine, Ropivacaine
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Anesthesia, Local, Anesthesia, Dental
Behavior of Children Related to Numbness After Dental Local Anesthesia
In children, behavior management is critical to the success of pediatric dental procedures. Most of the studies on local anesthesia performed in children deal with the question how to avoid or minimize pain during injection.
- Trial name
- NCT00363207
- Where
- 2 sites in Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization