Clinical trials: Anesthesia, Obstetric
Hypotension, Labor Complication
Leg Elevation to Prevent Hypotension During Labor
When hypotension is related to epidural placement, this can occur within 15-60 minutes after placement. The purpose of this study is to build upon this preliminary work and to use a randomized controlled trial to examine the…
- Trial name
- NCT05674838
- Testing
- Leg Elevation
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Thrombocytopenia, Postpartum Haemorrhage (PPH)
Prediction of Platelet Function Using Viscoelastic Test (ROTEM® Sigma) in Obstetric Anesthesia.
This prospective observational, non-interventional, single-center study aims to evaluate whether the viscoelastic parameter PLTEM, derived from ROTEM® sigma testing (EXTEM-A5 minus FIBTEM-A5), can accurately estimate platelet…
- Trial name
- NCT07616349
- Testing
- No Intervention: Observational Cohort
- Where
- Spain
- Volunteers
- 85 people
- Sponsor
- Nicolas Brogly
Obstetric Pain, Other Complications of Obstetric Anesthesia - Delivered
Epidural Dexamethasone for Labor Analgesia: the Effects on Ropivacaine Consumption and Labour Outcome
To assess the efficacy of epidural dexamethasone administration, compared to placebo, in reducing local anesthetics consumption during labor epidural analgesia in parturient women
- Trial name
- DEXAPER (NCT02857465)
- Testing
- Dexamethasone, Ropivacaine, Sufentanil
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Hypotension
Detecting Hypotension By Continuous Non-invasive Arterial Pressure Monitoring
The purpose of this study is to determine whether continuous non-invasive arterial pressure (CNAP) monitoring is beneficial to maintain maternal hemodynamic stability and improve the outcomes of maternal and fetal comparing with…
- Trial name
- NCT02532270
- Testing
- phenylephrine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
Placenta Accreta Spectrum
Spinal Versus General Anesthesia in Pregnancies With Placenta Accreta Spectrum: A Retrospective Comparative Study
Placenta accreta spectrum (PAS) is a serious pregnancy complication in which the placenta grows abnormally into the uterine wall.
- Trial name
- SAGA-PAS (NCT07406841)
- Testing
- spinal anesthesia, General Anesthesia
- Volunteers
- 50 people
- Sponsor
- Gaziantep City Hospital
Pregnancy
Use of Ultrasound in Obstetric Neuraxial Analgesia and Anesthesia Data Base
This is a data base building project on the use of pre-procedure ultrasound for the performance of labor epidural pain relief and spinal anesthesia for cesarean deliveries.
- Trial name
- NCT01192074
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Epidural Analgesia, Medical Education
Simulation-Based Training for Epidural Analgesia Placement
Epidural analgesia is the gold standard for labor pain management, widely recommended by the WHO and included in Italy's essential levels of care (LEA) since 2017.
- Conditions
- Epidural Analgesia, Medical Education, Obstetric Anesthesia
- Trial name
- NCT07056140
- Testing
- Epidural Simulation Training, Standard Clinical Training
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- University of Padova
Obstetric Anesthesia Care
Obstetric Anaesthesia And Analgesia Month Attributes - in COVID-19
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia and to evaluate the impact of COVID-19 pandemic on obstetric anesthesia and analgesia in Czech Republic and…
- Trial name
- OBAAMA-COV (NCT04912791)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 5,000 people
- Sponsor
- Brno University Hospital
Anesthesia, Spinal
Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgery
The following obstetric procedures are commonly performed with spinal anesthesia on labor and delivery: bilateral tubal ligation, external cephalic version, cerclage insertion, cerclage removal, minimally invasive fetal surgery…
- Trial name
- CLIMB (NCT03967288)
- Testing
- Chloroprocaine Injection [Clorotekal], Bupivacaine Hydrochloride 0.75% Injection Solution
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Hypotension, Spinal Anesthesia
Prophylactic Ondansetron for Preventing Spinal Anesthesia-Induced Hypotension in Elective Cesarean Section
Spinal anesthesia is the preferred technique for elective cesarean section, but it frequently causes maternal hypotension due to sympathetic blockade and the Bezold-Jarisch reflex, which can threaten both mother and baby.
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Section
- Trial name
- NCT07886151
- Testing
- Ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Obstetric Pain, Obstetric Anesthesia Problems
TAP Block vs LAWI for Analgesia Post-cesarean Section
Adequate pain control after cesarean delivery is a significant concern both for parturients and obstetric anesthesiologists. Transversus Abdominis Plane (TAP) block and local Wound infiltration with anesthetics are alternatives…
- Trial name
- NCT05447455
- Testing
- Transversus Abdominis Plane Block, Local anesthetic wound infiltration
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
High Risk Pregnancy, Multidisciplinary Communication
The Center for Peripartum Optimization
In January 2017 investigators started a Center for Peripartum Optimization (CPO) with the aim of optimizing a patient's clinical status in an outpatient setting to minimize unnecessary laboratory tests and studies, costly…
- Conditions
- High Risk Pregnancy, Multidisciplinary Communication, Communication, Obstetric Complication
- Trial name
- NCT03522909
- Testing
- Seen in clinic
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Johns Hopkins University
Cesarean Section, Anesthesia, Obstetric
Evaluation of the Typical Spinal Block During Cesarean Delivery
This will be a prospective, observational, single-center study to evaluate the accuracy of sensory testing by blunt 16-gauge plastic cannula during the 15 minutes after spinal injection for predicting spinal failure.
- Trial name
- NCT06206044
- Testing
- Intrathecal 1.6 ml 0.75% bupivacaine in 8.25% dextrose combined with 15 mcg fentanyl and 150 mcg preservative-free morphine
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Oregon Health and Science University
Spinal Anesthesia, Epidural; Anesthesia
Bupivacaine With Epidural Volume Extension
In this study the investigator will address the efficacy of using low dose bupivacaine spinal anesthesia (SA) in combination with epidural volume extension (EVE) for patients undergoing short obstetric procedures.
- Trial name
- NCT03110003
- Testing
- 10 mg Bupivacaine, 5 mg Bupivacaine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Labor Complication, Food Aspiration
Oral Intake During Labor
A randomized clinical trial (RCT) to evaluate the impact of unrestricted low fat, low residue oral intake during labor on maternal and neonatal outcomes as well as maternal satisfaction.
- Conditions
- Labor Complication, Food Aspiration, Complication of Anesthesia, Satisfaction
- Trial name
- NCT03276741
- Testing
- gastric soft/bland diet
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Cerebral Disorders Congenital, Premature Birth
Italian Survey on Paediatric and Neonatal MRI
Paediatric anaesthesia care in the Magnetic Resonance Imaging is a challenge for clinicians. The recent debate about the role of anaesthetic agent on neural development, encouraged an evaluation of their actual activity in this…
- Trial name
- NCT04775641
- Testing
- questionnaire
- Where
- Italy
- Volunteers
- 876 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Multiple Sclerosis
Obstetric Anesthesia and Analgesia and Multiple Sclerosis
Aim of the retrospective study was to evaluate the influence of the labour on the clinical course of the parturients with MS in selected 6 month follow-up interval and to evaluate to possible influence of the different…
- Trial name
- OBAANAMS (NCT03247894)
- Testing
- Data search
- Where
- Czechia
- Volunteers
- 70 people
- Sponsor
- Brno University Hospital
Pregnancy, Ceserean Section
Gastric Volume and Fasting Duration in Pregnant Women
This prospective observational study aimed to evaluate the effect of preoperative fasting duration on gastric volume and antral visibility in pregnant women undergoing elective cesarean section.
- Conditions
- Pregnancy, Ceserean Section, Gastric Volume, Postoperative Nausea and Vomit
- Trial name
- PREG-GAS (NCT07513675)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Obstetric Pain, Anesthesia, Local
Obstetric Placement Study Using EST
Combined spinal-epidural (CSE) is an established technique for providing labour analgesia to obstetric patients which provides rapid onset but unsustained analgesia.
- Trial name
- NCT04109365
- Testing
- Electrical Epidural Stimulation Test (EST)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Presentation; Breech, Complicating Pregnancy
Investigating Women's Views on the Management of a Breech Pregnancy
The investigators aim to perform a qualitative study to explore the views of women with a breech presentation on their management in general, and the use of anaesthesia or analgesia for ECV in particular.
- Trial name
- NCT02082795
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust