Clinical trials: Anesthesia, Recovery
Opioid-free Anesthesia
Opioid Free Anesthesia on the Quality of Early Recovery
To analyze and compare the effect of OFA scheme and traditional balanced anesthesia scheme on QoR15 after thyroidectomy, and further clarify the safety and rationality of OFA scheme in perioperative application of thyroid surgery.
- Trial name
- opioid-free (NCT05577962)
- Testing
- OFA group (group T)
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Breast Cancer
Effect of Midazolam Premedication Before Induction on the Functional Recovery After General Anesthesia in the Patients Undergoing Breast Surgery Due to Breast Cancer
Normally, higher levels of preoperational stress or anxiety affect behavior and recovery after the operation. Moreover, patients undergoing mastectomy are usually young women, and this demographic is known to experience higher…
- Trial name
- NCT01945476
- Testing
- midazolam premedication
- Where
- South Korea
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Procedural Sedation, Colonoscopy
Effect of Discontinuing Propofol After Cecal Intubation on Patient's Psychomotor Recovery Following Colonoscopy
This study investigates whether discontinuing the continuous intravenous infusion of propofol immediately after cecal intubation would reduce the patient's recovery time without compromising their comfort or convenience.
- Conditions
- Procedural Sedation, Colonoscopy, Cecal Intubation Success Rate, Propofol Adverse Reaction
- Trial name
- NCT07168135
- Testing
- propofol (drug)
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Opioid Use, Pain, Postoperative
Outcome of Multimodal Anesthesia Bern
In the context of the ongoing opioid crisis in the USA and Europe, reducing perioperative opioid use is a growing priority. Multimodal anesthesia (MMA) offers a patient-centered alternative to opioid-free anesthesia, combining…
- Conditions
- Opioid Use, Pain, Postoperative, Postoperative Complications, Postoperative Nausea
- Trial name
- NCT06985069
- Testing
- General anesthesia applying multimodal anesthesia, General anesthesia using conventional opioid-based regimen
- Where
- Switzerland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Postoperative Pain, Adverse Effects
Continuous Interscalene Block Results in Superior Recovery Throughout the First Postoperative Week
The investigators undertook this prospective, randomized trial to compare the recovery profile throughout the first postoperative week in patients receiving continuous (CISB) interscalene brachial plexus block, single injection…
- Trial name
- NCT01881776
- Testing
- ISB
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Anesthesia
Ultrasound-guided Serratus Plane Block for the Quality of Recovery After Modified Radical Mastectomy
Regional anesthesia improves quality of recovery after surgery in many studies. Ultrasound-guided serratus plane block is a novel technique which may be a viable alternative to current regional anesthetic techniques.
- Trial name
- NCT02691195
- Testing
- Ropivacaine, 0.9% Nacl
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Fujian Provincial Hospital
General Anesthesia, İnhalation Anesthetics
Effects of Anesthesia Type on QoR-40
To compare the effects of total intravenous anesthesia and inhalation anesthesia used for maintenance on postoperative recovery in patients undergoing septorhinoplasty surgery under general anesthesia, using the recovery quality…
- Conditions
- General Anesthesia, İnhalation Anesthetics, Quality of Recovery
- Trial name
- NCT06423313
- Testing
- maintenance of anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Opioid-Free Anaesthesia
Accelerated Recovery Following Opioid-free Anaesthesia in Supratentorial Craniotomy
Anaesthesia for craniotomy (open skull/brain) surgery focuses on maintaining blood supply to brain, avoiding factors that may lead to increased pressure in brain and aim for early neurological recovery.
- Trial name
- NCT05681429
- Testing
- Lignocaine, Dexmedetomidine, Sevoflurane, Paracetamol, Parecoxib
- Where
- Malaysia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Pain, Postoperative, Pain, Acute
Opioid Sparing Anesthesia in Cervical Spine Surgery
The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of lidocaine and ketamine in the same syringe versus remifentanyl analgesia in cervical spine…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Nociceptive
- Trial name
- NCT05717361
- Testing
- ketamine-lidocaine, Remifentanil
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Evangelismos Hospital
Delayed Emergence From Anesthesia, Postoperative Delirium
Trajectory of Recovery in the Elderly
The purpose of this study is to understand how elderly individuals regain their cognitive skills following general anesthesia. The investigators will compare an age stratified group of volunteers who will be evaluated with a…
- Conditions
- Delayed Emergence From Anesthesia, Postoperative Delirium, Postoperative Cognitive Dysfunction
- Trial name
- TORIE (NCT02275026)
- Testing
- Functional magnetic resonance imaging
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colonoscopy, Anesthesia
Comparison of Post Anesthetic Recovery Time in Sedated Patients for Colonoscopy
Colonoscopy is an important diagnostic and therapeutic tool in colon disorders. Different drugs and levels of sedation can be used in its accomplishment. There is no consensus on which is the ideal.
- Trial name
- CPART (NCT03813303)
- Testing
- Midazolam, Fentanyl, Propofol
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Emergence Delirium
Emergence Delirium and Recovery Time in Children
In this study, inhalation anesthesia procedure and intravenous anesthesia method will be compared in terms of emergence delirium and recovery time in children who are scheduled for dental treatment under general anesthesia.
- Trial name
- NCT03330613
- Testing
- PAEDS, TIVA, Inhalational anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Hip Fractures
Comparison of Pericapsular Nerve Group Block With Suprainguinal Fascia Compartment Block in Hip Fractures
Ultrasound-guided Supra-inguinal Fascia Iliaca compartment Block (SIFCB) and Pericapsular Nerve Group Block (PENG) are increasingly being used for postoperative analgesia for hip surgery.
- Trial name
- NCT06169462
- Testing
- PENG block, PENG block+ SIFCB
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Aminophylline, Dexmedetomidine
Aminophylline on Recovery in Functional Endoscopic Sinus Surgery Under Dexmedetomidine Hypotensive Anesthesia
This study will be conducted to evaluate the effect of intravenous aminophylline on hemodynamics and recovery of patients receiving dexmedetomidine infusion during functional endoscopic sinus surgery.
- Conditions
- Aminophylline, Dexmedetomidine, Functional Endoscopic Sinus Surgery
- Trial name
- NCT05738135
- Testing
- Aminophylline group, normal saline
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tanta University
ObsQor-10, Cesarean Section
Effect of Preoperative Oral Carbohydrate Drink on ObsQoR-10 Score After Elective Cesarean Under Neuraxial Anesthesia
The goal of this clinical trial is to determine whether a preoperative oral carbohydrate-rich clear drink can improve recovery in women undergoing elective cesarean section under neuraxial anesthesia.
- Conditions
- ObsQor-10, Cesarean Section, Preoperative Fasting
- Trial name
- NCT07204795
- Testing
- Distilled water group, Carbohydrate Drink
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Anesthesia
Perioperative Audio for Anaesthesia
Induction and emergence from propofol can be a difficult process for patients and healthcare workers, and long recovery times in particular can limit the rate of care.
- Trial name
- NCT05291832
- Testing
- Brain.fm Music, Spectrally-matched Noise
- Where
- United States
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Brain.fm, Inc.
Anesthesia, Analgesia
Genetic Variants and Perioperative Morbidity and Mortality
Prospective association study to analyse perioperative patients' outcome. Outcome comprises intraoperative and postoperative complications e.g.
- Conditions
- Anesthesia, Analgesia, Surgical Procedure, Operative
- Trial name
- NCT02124499
- Where
- Switzerland
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Quality of Recovery, Anesthesia
Improving ObsQoR-11 With Continuous Wound Infusion Versus Intrathecal Morphine After Elective Cesarean Delivery
The purpose of this prospective randomized double-blinded and controlled study is to evaluate the quality of recovery after elective cesarean delivery using the Obstetric Quality-of-Recovery-11 (ObsQoR-11) score at 24 hours…
- Conditions
- Quality of Recovery, Anesthesia, Postoperative Pain, Cesarean Section
- Trial name
- CIVIMEC (NCT05696678)
- Testing
- Intrathecal Morphine, Ropivacaine 0.2%
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Thyroid Cancer
Effect of Perioperative Intravenous Lidocaine Infusion and Magnesium Infusion on the Functional Recovery After General Anesthesia in the Patients Undergoing Thyroid Surgery
Studies have attempted to control pain and increase patients' recovery satisfaction following many kinds of operations by using as small an opioid analgesic dose as possible and adding a nonopioid analgesic to reduce the side…
- Trial name
- NCT02018276
- Testing
- Lidocaine, Magnesium
- Where
- South Korea
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Drug Interaction Potentiation
Analysis of Cisatracurium Consumption in Balanced Anesthesia With 1% Sevoflurane, and With Only Sevoflurane, Using a Closed-loop Computer Controlled System Infusion.
The aim in this study was to quantify the difference in cisatracurium and sufentanil consumption, and its recovery period, when patients are under balanced general anesthesia with 1% sevoflurane and patients under only…
- Trial name
- NCT01736371
- Testing
- 1% Sevoflurane, Propofol, Sevoflurane
- Where
- China
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University General Hospital