Clinical trials: Anesthesia, Spinal
Postoperative Pain, Complications
A Trial of Closed Hemorrhoidectomy Under Local Perianal Block Versus Spinal Anesthesia
Hemorrhoidectomy can be carried out under several modes of anesthesia. In western country hemorrhoidectomy usually be performed under general anesthesia, however there may be the complications resulted from general anesthesia…
- Conditions
- Postoperative Pain, Complications, Satisfaction
- Trial name
- NCT00925912
- Testing
- spinal block, Perianal block
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Anesthesia; Reaction, Anesthesia
Efficacy and Safety of Prilocaine 2% and Lidocaine 5% Hyperbaric Against Spinal Anesthesia in Post Cystoscopy Procedure
Regional anesthesia is defined as the temporary removal of nerve conduction and pain in certain areas of the body with local anesthetic drugs without causing loss of consciousness.
- Trial name
- NCT05834647
- Testing
- Prilocaine 2%, Hyperbaric Lidocaine 5%
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universitas Sebelas Maret
Postoperative Delirium, Postoperative Pain, Acute
Postoperative Delirium and Analgesia in Elderly Patients
This study aims to evaluate the effects of different postoperative analgesic approaches on postoperative delirium in elderly patients undergoing total knee arthroplasty.
- Trial name
- NCT07849517
- Testing
- adductor canal block and biFes block including bupivacain, Periarticular infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Pain Measurement, Visual Analog Pain Scale
The Analgesic Effect of Intrathecal Hydromorphone Injection on Spinal Anesthesia
The purpose of this study is to evaluate the adequate dose of intrathecal hydromorphone injection for postoperative pain relief after knee arthroscopic surgery.
- Trial name
- NCT01172782
- Testing
- Hydromorphone
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Regional Anesthesia, Anxiety
Uncontrolled Disinformation About Regional Anesthesia and Pregnant Patients.
Nowadays, hundreds of information about regional anesthesia are accessed from any internet search engine when a question is written about the methods of anesthesia that can be applied during C/S.
- Conditions
- Regional Anesthesia, Anxiety, Social Media Addiction, Spinal Anesthesia
- Trial name
- NCT05416541
- Testing
- social media
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Cesarean Section Complications, Hemodynamic Instability
Norepinephrine in Caesarian Section
Postspinal hypotension is a frequent maternal complication in caesarian delivery under neuraxial anesthesia which is most commonly treated with the administration of phenylephrine infusion.
- Conditions
- Cesarean Section Complications, Hemodynamic Instability, Foetal Stress
- Trial name
- NCT05264870
- Testing
- Norepinephrine
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Morbid Obesity
The Ultrasound Guided Versus Land-mark Location Method for Performing Spinal Anesthesia in Obese Parturients
This study will be investigated whether an ultrasound-assisted technique is better than a classical land-mark technique to facilitate spinal anesthesia in the lateral position in morbidly obese pregnant women with BMI ≥ 40 who…
- Trial name
- NCT05342922
- Testing
- Ultrasound group, Landmark group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Gynecologic Laparoscopic Surgery
Intrathecal Mg in Gynecologic Laparoscopic Surgeries.
The investigators aim to investigate the differences between intrathecal Bupivacaine + Mg sulfate in spinal anesthesia versus Bupivacaine on surgeon satisfaction and postoperative pain in gynecologic laparoscopic surgeries.
- Trial name
- NCT02671227
- Testing
- intrathecal Mg sulfate., intrathecal bupivacaine 15 mg.
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pruritus Caused by Drug
Ondansetron Use for Preventing Pruritus in Patients Undergoing Cesarean Section
Opioids are often added with a local anesthetic to enhance the duration and quality of spinal anesthesia for cesarean delivery patients.
- Trial name
- NCT06297499
- Testing
- Ondansetron 8mg
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Arthropathy of Hip, Arthropathy of Knee
Evaluation of the Duration of Bupivacaine Spinal Block in Orthopedic Procedures With and Without Epinephrine Wash
Bupivacaine spinal is commonly performed as the primary anesthetic for orthopedic procedures. In some cases the duration of the block is inadequate. An epinephrine wash is sometimes performed to prolong the duration of the block.
- Trial name
- NCT02619409
- Testing
- Bupivacaine Only, EPI25, EPI50 group
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pregnancy
Evaluation of Ultrasound (US) Assistance for Anesthesia Trainees for Caesarean Section Spinal Placement
Parturients receiving spinal anesthetic for Cesarean section will be randomized to have/not have pre-spinal ultrasound examination of their back.
- Trial name
- NCT01444638
- Testing
- Ultrasound examination
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Epidural and Spinal Anesthesia for Cesarean Delivery
How Sweet is it? Measurement of Glucose in Epidural and Spinal Fluid
When a woman requires a cesarean section after labour, anesthesia is usually provided by a pre-existing epidural. Occasionally, the epidural does not work. The anesthesiologist then may give a "spinal anesthetic".
- Trial name
- NCT01391702
- Where
- 2 sites in Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pregnancy
Use of Ultrasound in Obstetric Neuraxial Analgesia and Anesthesia Data Base
This is a data base building project on the use of pre-procedure ultrasound for the performance of labor epidural pain relief and spinal anesthesia for cesarean deliveries.
- Trial name
- NCT01192074
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Maternal Hypotension Syndrome, Cesarean
Norepinephrine Versus Ephedrin for Prevention of Post Spinal Anesthesia in Cesarean Section
Spinal anesthesia is still the gold standard anesthetic method for elective and urgent cesarean section, the post spinal hypotension remains the most frequent complication of this procedure and is still responsible of…
- Trial name
- NCT03719625
- Testing
- Ephedrine, Norepinephrine
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Pregnant, High Altitude
The Effect of Different Altitude Levels on Spinal Anesthesia in Cesarean Section Surgery
The aim of the researchers in this prospective study is to determine the differences, if any, in terms of anesthetic parameters among pregnant women who live at different altitudes and undergo cesarean section under neuraxial…
- Trial name
- altitude (NCT05715476)
- Testing
- cesarian surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Giresun University
Postoperative Pain, Pain
Comparison of Analgesic Efficacy of Intrathecal Bupivacaine Versus Bupivacaine Plus Dexmedetomidine in Patients Undergoing Orthopedic Surgeries.
Clinical Trial Overview: Intrathecal Bupivacaine vs. Bupivacaine + Dexmedetomidine Primary Objective Duration of Analgesia:** To compare the mean duration of postoperative pain relief between hyperbaric bupivacaine alone versus…
- Conditions
- Postoperative Pain, Pain, Orthopaedic Surgery, Anesthesia, Spinal
- Trial name
- NCT07866508
- Testing
- Dexmedetomidine plus Hyperbaric Bupivacaine, Hyperbaric bupivacaine % 0.5
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad
Nausea, Vomiting
Minimizing Nausea and Vomiting During Spinals for CS
In parturients undergoing Cesarean section under spinal anesthesia, co-loading of 1 liter of crystalloids, with placing the spinal, along with administering a phenylephrine infusion and glycopyrrolate, enables placing a spinal…
- Trial name
- NCT02872935
- Testing
- Glycopyrrolate, Normal Saline
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kokila N Thenuwara
Postoperative Shivering, Cesarean Delivery
Intravenous Dexmeditomidine for Prevention of Spinal Anesthesia Induced Shivering.
Intraoperative and post operative shivering is a common problem encountered in operating rooms and recovery suites. Shivering under spinal anesthesia has an incidence of 40-60%.
- Trial name
- NCT05342376
- Testing
- Dexmedetomidine Hydrochloride, Normal Saline
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rehman Medical Institute - RMI
Post Spinal Anesthesia Hypotension
Preoperative Oral Midodrine Versus Intraoperative Intravenous Norepinephrine in Preventing Post-spinal Anesthesia Hypotension in Cesarean Section: A Prospective Double-blind Randomized Clinical Trial
Neuraxial blockade such as spinal anaesthesia can cause severe hypotension due to pharmacological sympathectomy resulting in potential deleterious consequences for the patient, Prevention of this spinal anaesthesia induced…
- Trial name
- NCT06213935
- Testing
- Norepinephrine, Midodrine
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Healthy
Hemodynamic Measurements During Cesarean Section With Spinal Anesthesia
The purpose of this study is to determine the effect of low dose versus standard dose spinal anesthesia with and without intravenous phenylephrine-infusion on blood pressure, cardiac output and systemic vascular resistance.
- Trial name
- NCT00199784
- Testing
- Phenylephrine
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital