Clinical trials: Anesthesia, Spinal
Pregnancy, Cesarean Section
Effects of High Flow Humidified Oxygen on Umbilical Artery Acid-base Balance in Cesarean Section Under Spinal Anesthesia
Spinal anesthesia is the most commonly used anesthetic technique for cesarean section in developed countries, but vasodilation and a decrease in systemic vascular resistance caused by sympathetic blockade result in hypotension in…
- Conditions
- Pregnancy, Cesarean Section, Spinal Anesthesia
- Trial name
- NCT07515716
- Testing
- high-flow nasal oxygen, conventional nasal cannula oxygen
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Inguinal Hernia, Postoperative Pain
Ultrasound-Guided Ilioinguinal-Iliohypogastric Nerve Block Following Spinal Anesthesia Comparing Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Unilateral Inguinal Hernia Repair
This study evaluates and compares the pain-relieving efficacy and safety of adding either dexmedetomidine or nalbuphine to bupivacaine in an ultrasound-guided ilioinguinal-iliohypogastric nerve block for patients undergoing…
- Trial name
- NCT07837492
- Testing
- Bupivacaine, Nalbuphine, Dexmedetomidine
- Volunteers
- 102 people
- Sponsor
- Assiut University
Hip Arthroplasty, Knee Arthroplasty
Effect of Combined Use of Naloxone and Tramacet on Postop Analgesia in Elderly Patients Having Joint Replacement Surgery
Patients over 70 years of age, scheduled for joint replacement surgery will be randomized to tramacet/ naloxone plus morphine PCA or to morphine PCA to assess quality of analgesia in the postoperative period.
- Conditions
- Hip Arthroplasty, Knee Arthroplasty, Spinal Anesthesia
- Trial name
- NCT00679614
- Testing
- tramacet, naloxone, tramacet, Acetaminophen
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Pain, Complications
A Trial of Closed Hemorrhoidectomy Under Local Perianal Block Versus Spinal Anesthesia
Hemorrhoidectomy can be carried out under several modes of anesthesia. In western country hemorrhoidectomy usually be performed under general anesthesia, however there may be the complications resulted from general anesthesia…
- Conditions
- Postoperative Pain, Complications, Satisfaction
- Trial name
- NCT00925912
- Testing
- spinal block, Perianal block
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Cesarean Section, Hypotension
Prediction of Hypotension During Cesarean Delivery Using Positional Change of Hemodynamic Parameters
This was a prospective observational study between January 2022 and June 2022. The investigators included parturients aged 18 to 45 years, consenting, classified ASA II and III, scheduled for elective or emergency cesarean…
- Conditions
- Cesarean Section, Hypotension, Anesthesia, Spinal, Heart Rate
- Trial name
- NCT05685212
- Where
- Tunisia
- Volunteers
- 121 people
- Sponsor
- Mongi Slim Hospital
Cesarean Section, Postoperative Recovery
Enhanced Recovery Protocol Compliance and Quality of Recovery After Cesarean Delivery
This prospective observational study will evaluate whether adherence to enhanced recovery after cesarean delivery protocols is associated with postoperative recovery quality in women undergoing elective cesarean delivery under…
- Conditions
- Cesarean Section, Postoperative Recovery, Postoperative Pain
- Trial name
- ERAC-QoR (NCT07790471)
- Testing
- Assessment of Enhanced Recovery Protocol Compliance
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bursa City Hospital
Femoral Fracture, Blood Pressure
Cerebral Oxygenation and Spinal Anaesthesia in Elderly Patients With Hip Fracture
The aim of this study is to observe how the hemodynamic changes induced by spinal blockade affect cerebral oxygenation. Elderly patients are very frail. Hypotension is very frequent during spinal anaesthesia.
- Conditions
- Femoral Fracture, Blood Pressure, Cognitive Impairment
- Trial name
- NCT01647230
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital de Sabadell
Cesarean Section
Ultrasound Guided Spinal Anesthesia in Non Obese Obstetric Patients
The classical method for spinal anesthesia relies on the use of bony landmarks to identify the level and point of entry of the spinal needle.
- Trial name
- NCT01440400
- Testing
- Ultrasound guided spinal anesthesia
- Where
- United Arab Emirates
- Volunteers
- 150 people
- Sponsor
- Corniche Hospital
Pre-operative Anxiety, Spinal Anesthesia
Informative Video to Alleviate Anxiety and Improve Satisfaction in Elective Caesarean Section
Title: "Study of Informative Video on Alleviating Perioperative Anxiety and Improving Satisfaction Score in Obstetric Patients Undergoing Elective Lower Segment Caesarean Section Under Spinal Anaesthesia" Objective: This study…
- Conditions
- Pre-operative Anxiety, Spinal Anesthesia, Satisfaction, Patient
- Trial name
- NCT06545019
- Testing
- Informative Video on Perioperative Anxiety and Maternal Satisfaction
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Osteoarthritis, Hip, Osteoarthritis, Knee
Spinal Anaesthesia vs. General Anaesthesia for THA, TKA and UKA
The goal of this randomized clinical trial is to investigate the postoperative recovery following hip and knee arthroplasty procedures depending on the use of either spinal anaesthesia (SA) or general anaesthesia (GA).
- Trial name
- RCT SAGA (NCT05706844)
- Testing
- Spinal anesthesia, General anaesthesia
- Where
- 2 sites in Denmark
- Volunteers
- 222 people
- Sponsor
- Anders Troelsen
Postoperative Nausea and Vomiting, Postoperative Pain
Spinal Morphine and Atropine Added to General Anaesthesia for Nausea and Pain After Abdominal Laparoscopy
Laparoscopic abdominal surgery carries one of the highest risks of postoperative nausea and vomiting (PONV), and postoperative opioids given for pain are themselves emetogenic.
- Conditions
- Postoperative Nausea and Vomiting, Postoperative Pain, Anesthesia, Anesthesia Spinal
- Trial name
- NCT07851870
- Testing
- Intrathecal bupivacaine, morphine and atropine, General anaesthesia, Multimodal analgesia and antiemetic prophylaxis
- Where
- Indonesia
- Volunteers
- 63 people
- Sponsor
- Universitas Indonesia
Anesthesia, Cancer
Evaluation of Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia (ELSA Trial)
The use of intravenous lidocaine in continuous infusion in the perioperative period is associated with a reduction in postoperative pain scores, opioid use, incidence of nausea and vomiting, among other favorable outcomes.
- Trial name
- ELSA (NCT04741880)
- Testing
- Lidocaine IV, Saline
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension
Colloid Preload Versus Colloid Coload During Cesarean Deliveries
The investigators aimed to compare the methods colloid preloading and colloid coloading in terms of the incidence of maternal hypotension and impacts on neonatal outcomes.
- Trial name
- NCT02393196
- Testing
- hydroxyethyl starch (% 6 HES 130/0.4) (Voluven®), hydroxyethyl starch (%6 HES 130/0.4) (Voluven®)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sifa University
Anesthesia, Spinal, Sedation, Conscious
Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol Drinker
1. Adequate sedation with classical sedative agents, propofol 2. Sedation with propofol may induce paradoxical excitement response in heavy alcohol drinkers 3.
- Conditions
- Anesthesia, Spinal, Sedation, Conscious, Dexmedetomidine, Alcohol Drinking
- Trial name
- DEX (NCT02197403)
- Testing
- Dexmedetomidine, Propofol
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Chonnam National University Hospital
Cesarean Section Complications
Factors Influencing Bradycardia During Spinal Anesthesia in Obstetric Patients Undergoing Cesarean Section
The study titled "Factors Influencing Bradycardia During Spinal Anaesthesia in Obstetric Patients Undergoing Caesarean Section"" aims to investigate the causes and patterns of bradycardia in pregnant women receiving spinal…
- Trial name
- NCT07049705
- Where
- Pakistan
- Volunteers
- 289 people
- Sponsor
- Superior University
Analgesic Adverse Reaction, Cesarean Delivery Affecting Newborn
Oxycodone in Serum After Postoperative Oral Oxycodone in Caesarean Sections Under Spinal Anesthesia
All patients undergoing an elective caesarean section under spinal anesthesia will, according to the hospital routines, receive 10 mg oxycodone slow-release tablet when arriving at our postoperative care unit (PACU).
- Trial name
- NCT02717637
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital, Akershus
Conscious Sedation Under Spinal Anesthesia
The Optimal Effect Site Concentration of Propofol for Conscious Sedation in Elderly Male Patients Undergoing Urologic Surgery Under Spinal Anesthesia With or Without Intrathecal Fentanyl
Since intrathecal fentanyl is known to sedation effect, intrathecal fentanyl will result in lowering propofol requirement for conscious sedation under spinal anesthesia.
- Trial name
- NCT01232270
- Testing
- propofol
- Where
- South Korea
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Hip Fractures, Pain Management
Comparison of the Effects of Pericapsular Nerve Group (PENG), Suprainguinal Fascia Iliaca Compartment (S-FICB) and 3-1 Blocks on Comfort in Positioning for Unilateral Spinal Anesthesia and Postoperative Pain in Hip Fracture Surgery
Hip fracture is a common cause of surgery, especially in elderly patients. Unilateral spinal anesthesia in hip fracture surgery can prevent the undesirable effects of spinal anesthesia due to sympathetic blockade.
- Conditions
- Hip Fractures, Pain Management, Pain Postoperative, Spinal Anesthesia
- Trial name
- NCT05912101
- Testing
- Pericapsular Nerve Group Block, Suprainguinal Fascia Compartment Block, 3-1 Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bozyaka Training and Research Hospital
Hypotension
Spinal Anesthesia Induced Hypotension During Cesarean Section
The purpose of this study is to compare two methods for preventing low blood pressure associated with spinal anesthesia during Cesarean sections.
- Trial name
- NCT00846651
- Testing
- Colloid administration, Crystalloid administration, phenylephrine infusion
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Milton S. Hershey Medical Center
Galvanic Skin Response, Skin to Skin Contact
The Effect of Skin-to-skin Contact Between Mother and Newborn
A 2016 Cochrane Review shows that skin-to-skin contact promotes breastfeeding and strengthens mother-infant bonding. For the mother, skin-to-skin contact was found to promote early separation of the placenta, reduce postpartum…
- Trial name
- NCT06827522
- Testing
- Birth Under General Anesthesia, Birth Under Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- TC Erciyes University