Clinical trials: Anesthesia,General
Postoperative Sore Throat, Cough, Hoarseness
Air Versus Lignocaine for Endotracheal Tube Cuff Inflation and Effect on Postoperative Sore Throat and Intracuff Pressure
Endotracheal Tube (ETT) is frequently used for GA (general anesthesia) to deliver oxygen and volatile anesthetic agents to the patient and serves as a channel for anesthetic gases.
- Trial name
- NCT07315490
- Testing
- Xylocaine
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- PAEC General Hospital, Islamabad
Sore Throat After Thyroid Surgery
Transcutaneous Electrical Acupoint Stimulation on Postoperative Pharyngeal Pain
Thyroid surgery is a common type of surgery in thyroid and breast surgery, mainly used to treat benign and malignant thyroid diseases.
- Trial name
- NCT07117123
- Testing
- Transcutaneous electrical acupoint stimulation, No electrical stimulation
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Dexmedetomidine, Postoperative Delirium
Different Administration Routes of Dexmedetomidine on Postoperative Delirium
Intravenous dexmedetomidine has been reported to decrease the occurrence of postoperative delirium (POD) in elderly patients. Nevertheless, some previous studies have indicated that intratracheal dexmedetomidine and intranasal…
- Conditions
- Dexmedetomidine, Postoperative Delirium, General Anesthesia
- Trial name
- NCT05952050
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Burst Suppression, General Anesthesia
Interrater Variability for the Identification of Anesthetic-induced Burst Suppression EEG
Burst suppression describes a specific EEG pattern that can generally indicate a too deep general anesthesia. The pathophysiology of anesthetic-induced Burst Suppression may be distinctly different from the pathophysiology of…
- Conditions
- Burst Suppression, General Anesthesia, Electroencephalogram
- Trial name
- NCT05508386
- Testing
- MATLAB-based interface, showing 50 EEG traces, classification of the EEG-pattern as Burst Suppression possible, yes, no.
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Atelectasis
Effects of Small-dose S-ketamine on Anesthesia-induced Atelectasis in Anesthetized Patients Accessed by Pulmonary Ultrasound
Background: Atelectasis occurs in the majority of patients with general anesthesia, which can lead to postoperative pulmonary complications (PPCs) and affect the postoperative outcome.
- Trial name
- NCT04745286
- Testing
- S-ketamine, normal saline group
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Elective Urological Surgery
New Formula for Selection of Proper Size of Endotracheal Tube (ETT) in Children: Ultrasonographic Examination
Choosing the adequate size of endotracheal tube(ETT) in pediatric patients is important in all anesthesiologists, pediatricians, and critical care specialists.
- Trial name
- NCT01227161
- Where
- South Korea
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Anesthesia, General, Anesthesia, Intravenous
Evaluation of a Novel Closed-loop Propofol and Remifentanil System Guided by Bispectral Index Compared to a TCI Open-loop System
Closed loop system in intravenous anesthesia is more effective to maintain depth of anesthesia compared with manual system open, it is unclear what driver and variables to achieve this goal be more physiological; in the…
- Trial name
- NCT02492282
- Testing
- Closed-Loop propofol and remifentanil system by Bispectral Index, Open-Loop propofol and remifentanil by Target Controlled Infusion, propofol
- Where
- Colombia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Neurotoxic Effect of Sevoflurane-Based Anaesthesia
Evaluation of Neurotoxic Effect of Sevoflurane-Based AnaesthesiaGuided by Short-Term Olfactory Identification
Nowadays there is increasing doubts about the safety of anesthesia . Anesthesiologists have to console the worried patients, who are anxious about the potential risks of anesthetic-induced brain damage, by suggesting that any…
- Trial name
- NCT03726580
- Testing
- Sevoflurane
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Tanta University
Cerebral Oxygenation
Effect of Left Paratracheal Pressure on Cerebral Oxygenation During General Anesthesia
Left paratracheal pressure (LPP) has been proposed as an alternative to cricoid pressure to reduce the risk of regurgitation during induction of general anesthesia.
- Trial name
- PARANIRS (NCT07778303)
- Testing
- Left Paratracheal Pressure, Cricoid Pressure
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Clinique Saint-Luc
Deep Hypnotic Time, Emergence Time
Comparison of DHT Duration in Geriatric Patients Using BIS Monitoring
Without adequate monitoring, administration of anesthetic agents can create unnecessary deeper anesthetic plane in geriatric population.
- Conditions
- Deep Hypnotic Time, Emergence Time, Geriatric Population, General Anesthesia
- Trial name
- NCT06394362
- Testing
- Bispectral index monitor
- Where
- Indonesia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Apnea, Ventilation Therapy; Complications
THRIVE Apneic Ventilation With Standardized Airway Management During General Anesthesia.
Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) denotes the use of high-flow humidified nasal oxygen system (for example Optiflow®) as an alternative ventilation modality for an anesthetized patient without…
- Conditions
- Apnea, Ventilation Therapy; Complications, Respiratory Acidosis
- Trial name
- NCT03797859
- Testing
- Apneic ventilation
- Where
- 2 sites in Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet