Clinical trials: Anesthesia; Regional
Knee Osteoarthritis, Flexion Contracture of Knees
IPICK Blocking for TKA With Moderate Flexion Contracture
Clinical effect of intermittent multiple IPICK blocking on TKA for knee osteoarthritis with flexion contracture between 5 ° and 10 °
- Conditions
- Knee Osteoarthritis, Flexion Contracture of Knees, Anesthesia, Local
- Trial name
- NCT04603950
- Testing
- CACB+IPACK, CACB
- Where
- China
- Volunteers
- 42 people
- Sponsor
- The First Hospital of Jilin University
Femoral Fracture
Dose Finding Study for Continuous Spinal Anaesthesia
Fixation of fractured neck of femur is a common Orthopedic surgery. Anaesthesia can be challenging in some cases like in haemodynamical unstable patients.
- Trial name
- NCT01680120
- Testing
- Continuous spinal anaesthesia
- Where
- Ireland
- Volunteers
- 15 people
- Sponsor
- Cork University Hospital
Postoperative Nausea and Vomiting
Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Vitrectomy Under Local Anesthesia
Vitreoretinal surgery is associated with a considerable incidence of postoperative nausea and vomiting (PONV), which is reported to be as high as 60%.
- Trial name
- NCT02386059
- Testing
- Dexamethasone, Ondansetron, Dexamethasone + Ondansetron
- Where
- 4 sites in Italy
- Volunteers
- 1,200 people
- Sponsor
- University of Catania
Myoma;Uterus, Polyp Uterus
Paracervical Block Versus Transcervical Block in Outpatient Procedural Hysteroscopy
Hysteroscopy is a minimally invasive, diagnostic and therapeutic gynecological surgical technique and the gold standard in the study of the uterine cavity.
- Trial name
- NCT05967936
- Testing
- Bupivacaine Injection
- Where
- Canada
- Volunteers
- 242 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Pain, Postoperative
Thoracic Paravertebral Block for Postoperative Analgesia After Video-assisted Thoracic Surgery.
The use of paravertebral catheters is a recommended technique to achieve postoperative analgesia after thoracic surgery. To date there is no consensus on which drug regime (local anesthetics with or without opioid) is best.
- Trial name
- PARAVI (NCT01082744)
- Testing
- Ropivacaine + Sufentanil, Ropivacaine
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Hospices Civils de Lyon
Contraception, Pain, Acute
Empathy Through Pain Control: Lidocaine Gel vs. Placebo Prior to IUD Placement
The goal of this research study is to learn more about how different uses of a numbing medication might affect pain levels while getting an IUD placed.
- Conditions
- Contraception, Pain, Acute, Anesthesia, Local
- Trial name
- EPIC3 (NCT06974032)
- Testing
- Xylocaine jelly 2%, Surgilube
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Pain, Needle Phobia
Pain Perception of Needle-free System
The purpose of this study is to evaluate and compare the pain perception associated with a needle-free injection system( Comfort-In) and dental injection method in filling and pulpotomy treatments
- Conditions
- Pain, Needle Phobia, Anxiety, Dental Fear
- Trial name
- NCT04653974
- Testing
- Needle-free injection
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Anxiety Disorders
Regional Anesthesia / Peripheral Nerve Block and General Anesthesia on Preoperative Anxiety
The researchers aimed to investigate that preoperative anxiety scores of patients who are informed about the anesthesia before surgery with using State-Trait Anxiety Inventory and Amsterdam preoperative anxiety and information…
- Trial name
- NCT02511210
- Testing
- regional anesthesia, general anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Cukurova University
Pain
Dexamethasone & Bupivacaine vs Bupivacaine Alone in Combined Femoral and Sciatic Nerve Block for Perioperative Analgesia in Patients Undergoing Lower Limb Surgeries
In regional anesthesia local anaesthetics alone provide analgesia for not more than 4-8 hours. Increasing the duration of local anaesthetic action is often desirable because it prolongs surgical anaesthesia and analgesia.
- Trial name
- NCT02576782
- Testing
- Perineural Dexamethasone and bupivacaine, Systemic Dexamethasone plus perineural bupivacaine, intravenous saline plus perineural bupivacaine
- Volunteers
- 63 people
- Sponsor
- Sherif Mohamed Abd el moneim Soaida, MD
Chronic Pain Post-Procedural
Block REducing Pain After Surgery Trial
This observational study evaluates difference in chronic pain after six months from surgery between patients who received PECS block and general anesthesia versus general anesthesia alone.
- Trial name
- BREAST (NCT03448913)
- Testing
- PECS block
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- University of Padova
Nerve Block
Regional Anesthesia for Major Surgery of the Foot. Levobupivacaïne Ropivacaine 0.5% Versus 0.5% in the Sciatic Block Through médiofémorale
Ropivacaine 0.5% and 0.5% in levobupivacaïne are used in regional anesthesia for major surgery of the foot. The literature does not highlight a significant difference in terms of onset of action between these two molecules to…
- Trial name
- SCIALERO (NCT00956709)
- Testing
- levobupivacaïne 0,5 %, ropivacaïne 0,5 %
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Nantes University Hospital
Arthropathy of Knee, Anesthesia
IPACK Nerve Block for Total Knee Arthroplasty
Double-blind, randomized controlled clinical trial to test the efficacy of IPACK on postoperative opioid consumption, patient satisfaction, pain scores, mobility, and several other secondary outcomes in adults undergoing primary…
- Trial name
- NCT03921034
- Testing
- Ropivacaine, Saline
- Volunteers
- 72 people
- Sponsor
- Ochsner Health System
Anesthesia, Local
A Study of the Safety and Anesthetic Effect of AG-920 Topical Ophthalmic Solution
This is a Phase 3, randomized, placebo-controlled, double masked, parallel design study in healthy subjects performed in the US.
- Trial name
- NCT04829344
- Testing
- AG-920
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- American Genomics, LLC
Anesthesia, Local
Efficacy of Transversus Abdominis Plane Block
This study aims to assess the efficacy of Transversus Abdominus Plane (TAP) blocks, a well-established anesthetic technique, to decrease the amount of post-operative pain in patients who undergo minimally invasive gynecologic…
- Trial name
- NCT06274307
- Testing
- Transversus abdominis plane block
- Where
- 2 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Justin Hruska
Regional Anesthesia, Sciatic Nerve Block
Comparing Through-the-Needle With Suture-Method Catheter Designs for Popliteal Nerve Blocks
Following painful surgical procedures, postoperative analgesia is often provided with a single-injection peripheral nerve block.
- Trial name
- NCT03442036
- Testing
- Suture-Method Technique, Through-the-Needle Technique
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Breast Cancer
Comparing Local Anesthesia With General Anesthesia for Breast Cancer Surgery
The purpose of this study is to determine therapeutic benefits by local anesthetic technique for breast cancer.
- Trial name
- NCT00938171
- Testing
- Local anesthesia, General anesthesia
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Mackay Memorial Hospital
Breast Cancer, Pain, Postoperative
Comparative Sensory Mapping of Regional Anesthesia Techniques in Breast Cancer Surgery
Various regional anesthesia techniques, either individually or in combination, can be utilized for analgesia in breast cancer surgery.
- Trial name
- NCT06911892
- Testing
- Group Serratus Anterior Plane Block, Group Parasternal Block, Group Interpectoral+Pectoserratus Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Samsun University
Femoral Neck Fractures, Regional Anesthesia
Comparison of Regional Anaesthesia Methods for Femoral Neck Fracture Surgery
Femoral fracture surgery is frequently performed especially in geriatric population. Compared to general anaesthesia, regional anaesthesia is preferred to general anaesthesia in the geriatric patient population due to lower…
- Trial name
- NCT06224439
- Testing
- hypobaric spinal anaesthesia, lumbar plexus block, hyperbaric spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Analgesia, Anesthesia, Local
Suprainguinal Fascia Iliaca Block in Knee Arthroplasty
Total knee arthroplasty is the most commonly performed orthopedic surgery, especially in patients with advanced gonarthrosis and limited joint movement. After total knee arthroplasty, patients experience unbearably severe pain.
- Trial name
- NCT06386575
- Testing
- control group; Patients who received physiological saline, suprainguinal fascia block; Patients receiving local anesthetic
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya City Hospital
Biliary Disease
Unilateral TAP Block vs Trocar Insertion Sites Infiltration Anesthesia in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is a commonly performed operation in general surgery practice. Peripheral nerve block methods commonly used for analgesia after this operation are: transversus abdominis plane block (TAP) and trocar…
- Trial name
- NCT03543202
- Testing
- Transversus abdominis plane block, local infiltration anesthesia, Intravenous patient controlled analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital