Clinical trials: Anesthesia, completed
Stress Reaction
Effect of Location of Tetanic Stimuli on Photoplethysmogram
The effect of the location of tetanic stimulus on photoplethysmography signals will be studies in patients under general anesthesia.
- Trial name
- NCT03648853
- Testing
- Tetanic Stimulus
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Prostate Tumor
Remimazolam Versus Propofol for General Anesthesia Induction in Patients on Renin-angiotensin System Blockers Undergoing Robot-assisted Laparoscopic Prostatectomy
The investigators conduct a random assignment into either the remimazolam group or the propofol group. Depending on the group assignment, either remimazolam (0.2 mg/kg) or propofol (1.0 mg/kg) is administered.
- Trial name
- NCT06093971
- Testing
- remimazolam, Propofol
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Yonsei University
Intraoperative Shivering, Ketamine With Shivering
Comparison of Ketamine Plus Dexamethasone Versus Ketamine Alone for Prevention of Severe Shivering After Spinal Anesthesia in Cesarean Section
Shivering is one of the most distressing events of the birth experience for patients. Shivering that occurs with spinal anesthesia is a frequent event, with a reported incidence of up to 50-65%.
- Conditions
- Intraoperative Shivering, Ketamine With Shivering, Dexamethasone for Shivering, Severe Shivering
- Trial name
- NCT06091657
- Testing
- Ketamine Hydrochloride
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Kasr El Aini Hospital
Postoperative Pain
Catheter-based Peripheral Regional Anesthesia After Total Knee Arthroplasty
BACKGROUND Total knee arthroplasty can be severely painful, and peripheral regional anesthesia is highly recommended as part of the perioperative pain treatment.
- Trial name
- API-KNEE (NCT03372265)
- Testing
- Ropivacaine 0.2%
- Where
- Denmark
- Volunteers
- 111 people
- Sponsor
- Nordsjaellands Hospital
Airway Complications
Frequency of Airway Complications During General Anaesthesia After Introducing Five Handling Adaptations
The purpose of this study is to determine if five simple adaptations in airway management of patients undergoing general anaesthesia can reduce minor and major airway complications.
- Trial name
- Papaya (NCT02743767)
- Testing
- Introducing five different treating adaptations
- Where
- Switzerland
- Volunteers
- 7,455 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Anesthesia
A New and Innovative Method for CO2 Removal in Anesthetic Circuits
The drawbacks of chemical CO2 absorbers include the production of compounds harmful to patients that also lead into increased cost and environmental impact, as well as the daily disposal of compound special waste.
- Trial name
- memsorb (NCT03014336)
- Testing
- memsorb
- Where
- 2 sites in Canada
- Volunteers
- 286 people
- Sponsor
- DMF Medical Incorporated
Spinal Anesthesia
Predictive Value of Ultrasound Measurement of the Dural Sac Volume on the Sensory Level in Spinal Anesthesia
The purpose of this study is to investigate whether the dural sac volume as determined by a geometrical calculation following multilevel measurements of its transverse area and length by ultrasound imaging, correlates with the…
- Trial name
- NCT01624844
- Testing
- Geometrical calculation of dural sac volume
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Blood Pressure, Heart Rate
The Effects of Medical Clowning on Blood Pressure and Pulse Rate of Patients Undergoing Cataract Surgery Under Local Anesthesia
Cataract surgery is the most prevalent surgical procedure. Since most candidates are elderly patients, hypertension is common among these patients.
- Trial name
- NCT00806832
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- HaEmek Medical Center, Israel
Anesthesia, General
General Anesthesia and Autonomic Nervous System in Children
The objective of the ANESPEDIA study is to describe in a pediatric population (aged from 4 to 8 years old) receiving elective surgery, the impact of general anesthesia on autonomic nervous system and their kinetics of early…
- Trial name
- ANESPEDIA (NCT02714777)
- Testing
- Autonomic nervous system activity
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Inguinal Hernia, Postoperative Pain
Comparing Erector Spinae Plane (ESP) and Transversus Abdominis Plane (TAP) Block in Inguinal Hernia
The Erectore Spinae Plane Block (ESP Block) is a recently described technique for regional anesthesia that has shown promising results in the treatment of pain after thoracic surgery.
- Conditions
- Inguinal Hernia, Postoperative Pain, Anesthesia, Local, Anesthesia Complication
- Trial name
- TAPESP (NCT04750512)
- Testing
- ESP block, TAP block
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Ghielmini Enea
Anesthesia, Pain
Lidocaine Compared to Magnesium Sulfate to Prolong Spinal Anesthesia: Non-inferiority Randomized Clinical Trial
This study evaluates the addition of continuous infusion of lidocaine or continuous infusion of magnesium sufate in the duration of spinal anesthesia.
- Trial name
- NCT03725228
- Testing
- Magnesium Sulfate, Lidocaine
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Brasilia University Hospital
Anesthesia, Obestetric
Regional Anesthesia of Cesarean Section
Beta trace protein assay is an indicator of post-spinal CSF leak that predicts the degree of post-spinal headache.
- Trial name
- NCT03556267
- Testing
- spinal needle
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Induction and Maintenance of General Anesthesia
A Clinical Trial Evaluating the Efficacy and Safety of HSK3486 Injectable Emulsion in Elective Surgery Patients
This is a multi-center, randomized, open-label, positive-controlled (propofol) phase II clinical trial. The study plans to enroll approximately 46 eligible subjects.
- Trial name
- NCT04048811
- Testing
- HSK3486, Propofol, Propofol HSK3486
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
PONV, BIS
Effect of BIS-Guided Anesthesia on Postoperative Nausea and Vomiting in Pediatric Patients
This randomized controlled trial will evaluate the effect of bispectral index (BIS)-guided anesthesia on postoperative nausea and vomiting (PONV) in children aged 3-8 years undergoing elective adenoidectomy.
- Trial name
- NCT07189845
- Testing
- BIS GROUP, CONTROL GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Engin Çetin
Ecchymosis, Adverse Anesthesia Outcome
Comparison of Lidocaine With and Without Adrenaline for Reducing Ecchymosis
This randomized, double-blinded controlled trial evaluates whether lidocaine with adrenaline reduces bruising (ecchymosis) more effectively than lidocaine without adrenaline among women undergoing contraceptive implant insertion…
- Conditions
- Ecchymosis, Adverse Anesthesia Outcome, Complications Associated With Device, Bleeding
- Trial name
- CLEAR (NCT07897201)
- Testing
- 1% Lidocaine with adrenaline, 1% Lidocaine
- Where
- Thailand
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Vitreoretinal Surgeries, Postoperative Nausea and Vomiting
Different Peribulbar Blocks With SPI-guided Anaesthesia for VRS (P&MSPIVRS)
The aim of this randomized trial is to assess the efficacy of preventive analgesia using different peribulbar blocks (PBB) under SPI-guided anaesthesia for vitreoretinal surgery (VRS), presence of PONV (postoperative nausea and…
- Conditions
- Vitreoretinal Surgeries, Postoperative Nausea and Vomiting, Postoperative Pain, Oculocardiac Reflex
- Trial name
- PBBVRS (NCT03413371)
- Testing
- paracetamol, 0,5 % bupivacaine with of 2% lidocaine, 1 % Ropivacaine
- Where
- Poland
- Volunteers
- 184 people
- Sponsor
- Medical University of Silesia
Status; Splenectomy
Effects of Desflurane Versus Propofol on Hemostasis During Splenectomy
The aim of this prospective randomized study is to evaluate the perioperative effects of inhalational anesthesia (desflurane) and intravenous anesthesia (propofol) on hemostasis in patients undergoing splenectomy with liver…
- Trial name
- NCT02079064
- Testing
- Desflurane, Propofol
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Theodor Bilharz Research Institute
Opioid Free Anaesthesia, Opioid Anaesthesia
Opioid Free Anaesthesia in Cardiac Surgery With Cardiopulmonary Bypass
Since the 1990s, the concept of anesthesia without morphine (OFA) has been developed. The principle is based on the fact that in a sleeping patient a sympathetic reaction marked by hemodynamic changes does not reflect a painful…
- Trial name
- OFACAR 1 (NCT03816592)
- Testing
- Opioid free anaesthesia, Opioid anaesthesia
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Anesthesia, Caudal
Use of Caudal Anesthesia Supplemented With Morphine in Children Undergoing Renal Surgery
The aim of this study is to test an efficacy and safety of supplemented by Morphine caudal anesthesia in children who undergo renal surgery in our department.
- Trial name
- NCT01869036
- Testing
- caudal anesthesia, caudal anesthesia supplemented with morphine
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Shaare Zedek Medical Center
Cardiac Output
Comparability of Transesophageal Echocardiography and FloTrac/Vigileo System Three Different Positions
The use of cardiac output monitoring to guide intraoperative fluid management and inotropic drugs as part of a hemodynamic therapy algorithm reduce the complication rate in major abdominal surgery.
- Trial name
- NCT05508711
- Testing
- FloTrac/Vigileo system (© Edwards Lifesciences) (Edwards Lifesciences, Irvine, CA) device
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles