Clinical trials: Anesthesia Care
Intensive Care Unit, Mechanical Ventilation
Pharmacokinetic Study of Continuous Infusion of Remazolam in Mechanically Ventilated Patients in ICU
To study the pharmacokinetics of continuous infusion of remazolam in ICU mechanically ventilated critically ill patients, and the characteristics of PK in patients with liver failure; to explore whether liver failure affects the…
- Conditions
- Intensive Care Unit, Mechanical Ventilation, Anesthesia, Liver Failure
- Trial name
- NCT05480787
- Testing
- Remimazolam 0.1mg/kg/h, Remimazolam 0.3mg/kg/h, Remimazolam 0.5mg/kg/h
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Monitored Anesthesia Care, Cardiac Surgery
Monitored Anesthesia Care Versus Intubated General Anesthesia for Open Heart Surgery Under Cardiopulmonary Bypass
Though Cardiac surgery under cardiopulmonary bypass (CPB) under epidural anesthesia in conscious patients is associated with increased risk of epidural hematoma.
- Conditions
- Monitored Anesthesia Care, Cardiac Surgery, Postoperative Recovery
- Trial name
- NCT05011617
- Testing
- Non-intubation and monitoring anesthesia care (MAC)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- ShuGuang Hospital
Monitored Anesthesia Care
The Value of Integrated Pulmonary Index Monitoring in Detecting Respiratory Events
Integrated Pulmonary Index (IPI) is a tool that provides numerical values on a scale of 1-10 based on physiological parameters such as peripheral oxygen saturation (SpO2), pulse rate, respiratory rate, end-tidal carbon dioxide…
- Trial name
- NCT05356819
- Testing
- Smart Capnography™, Microstream®
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Samsun Education and Research Hospital
Complication of Surgical Procedure, Complication of Anesthesia
A Novel Classification for the Assessment and Grading of Unexpected Events in Pediatric Surgery: The Clavien-Madadi Classification
Postoperative adverse events may be associated with substantial morbidity and mortality. However, inconsistent definitions of complications and unexpected events have limited accurate analysis of surgical outcomes.
- Conditions
- Complication of Surgical Procedure, Complication of Anesthesia, Complication,Postoperative, Complication of Medical Care
- Trial name
- ComPedS (NCT05277441)
- Testing
- Novel severity grading system of unexpected events in pediatric surgery
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- Hannover Medical School
COVID-19, Obstetric Anesthesia Problems
Outcomes of Obstetric Patients With COVID-19 Disease in the ICU
Although several studies are conducted in the general population researching the clinical and laboratory parameters predicting the progression to severe disease in COVID-19, the data are very few in obstetric patients.
- Conditions
- COVID-19, Obstetric Anesthesia Problems, Intensive Care Unit, Morality
- Trial name
- NCT05264987
- Testing
- intensive care follow-up
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Turkiye Yuksek Ihtisas Education and Research Hospital
Anesthesia, Adverse Effect of Handovers of Anesthesia Care
Impact of Handover of Anesthesia Care on Adverse Postoperative Outcomes
Our goal is to conduct a prospective, national, randomized-controlled, multicenter trial to investigate the effect of handover of anesthesia care on the occurrence of adverse outcomes in the perioperative period.
- Trial name
- HandiCAP (NCT04016454)
- Testing
- Intervention
- Where
- 11 sites in Germany
- Volunteers
- 1,817 people
- Sponsor
- University Hospital Muenster
Obstetric Anesthesia Care
Obstetric Anaesthesia And Analgesia Month Attributes - in COVID-19
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia and to evaluate the impact of COVID-19 pandemic on obstetric anesthesia and analgesia in Czech Republic and…
- Trial name
- OBAAMA-COV (NCT04912791)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 5,000 people
- Sponsor
- Brno University Hospital
Perioperative Anxiety, Preanesthetic Medication
Handheld-multimedia Versus Oral Midazolam in Pediatric on Perioperative Anxiety
The first goal of this study is to compare the efficacy and safety between anxiolysis by multimedia-distraction with an IPAD versus anxiolysis by premedication with midazolam prior to the induction.
- Conditions
- Perioperative Anxiety, Preanesthetic Medication, Inhalation Anesthesia, Ambulatory Surgery
- Trial name
- NCT04273035
- Testing
- Midazolam oral solution, IPAD
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitair Ziekenhuis Brussel
Spinal Anesthesia, Task Sharing in Anesthetic Delivery in Areas With Limited Access to Care
Task-based Credentialing for Medical Officers in Spinal Anesthesia
Test the safety and effectiveness of training medical officers in the provision of spinal anesthesia in a rural hospital context using a non-inferiority randomized trial.
- Trial name
- NCT04438811
- Testing
- delivery of the spinal anesthetic by a trained medical officer, delivery of spinal anesthetic by a consultant anesthetist
- Where
- 4 sites in United States, India
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Quality of Life, General Anesthesia
Assessment of Changes in Oral Health-related Quality of Life , Oral Hygiene Status and Body Growth in CSHCN Following Dental Treatment Under General Anaesthesia
evaluation of the impact of dental treatment under GA on oral health-related quality of life (OHRQoL) in children with SHCN with severe dental caries with Assessment in change in oral health status and the impact on children's…
- Conditions
- Quality of Life, General Anesthesia, Children With Special Health Care Needs, Body Mass Index
- Trial name
- NCT04861675
- Testing
- Full mouth rehabilitation under general anaesethia
- Volunteers
- 10 people
- Sponsor
- Cairo University
Monitored Anesthesia Care
Magnesium Sulphate Versus Fentanyl Sedation During Burr-hole Surgery
MgSO4 was found to reduce the perioperative anesthetic and analgesic requirements when used as an adjuvant to general anesthesia. Fentanyl is a potent opioid and used as adjuvant to other sedatives in awake craniotomy procedure.
- Trial name
- NCT03854812
- Testing
- Magnesium Sulphate, Fentanyl, Propofol
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Kasr El Aini Hospital
Music Therapy, Perioperative Care
Effect of Music in Intraoperative Period
Background and Aims: Music therapy has a wide range of uses in health care practice. The aim of this study was to investigate the effects of intraoperative music played during spinal anesthesia operation on the patients'…
- Conditions
- Music Therapy, Perioperative Care, Postoperative Pain, Anxiety
- Trial name
- NCT04485650
- Testing
- music therapy, sedated group, non-sedated group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Abant Izzet Baysal University
Effect of Anesthesia in Postoperative Pain, Effect of Anesthesia in Extubation Time
Opioid Versus Non-opioid Anesthesia for Ambulatory Surgery in Children
The investigators intend to study the safety and effectiveness of opioid free anesthesia compared to opioid anesthesia in ambulatory surgery in children, regarding postoperative pain, hemodynamic stability, agitation and…
- Conditions
- Effect of Anesthesia in Postoperative Pain, Effect of Anesthesia in Extubation Time, Effect of Anesthesia in Discharge Time From Postanesthesia Care Unit, Effect of Anesthesia in Postoperative Adverse Events
- Trial name
- NCT03979469
- Testing
- Ketamine, dexmedetomidine, fentanyl, remifentanil
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
Burnout, Professional, Intensive Care
National French Survey on Psychological Distress at Work of Anesthesia and Intensive Care Residents
Psychological distress is a significant problem for healthcare professionals and students in training. The investigator question the prevalence of this problem in French residents in anaesthesia and intensive care training.
- Conditions
- Burnout, Professional, Intensive Care, Anesthesia, Depression, Anxiety
- Trial name
- PSY-DESAR (NCT04350151)
- Testing
- no intervention
- Where
- France
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Facteurs Humains en Santé
Bispectral Index, Monitored Anesthesia Care
Patient's Satisfaction of Bispectral Index-guided Monitored Anesthesia Care
The investigators will evaluate the effect of bispectral index-guided titration of sedation during ear surgery under monitored anesthesia care on participant's satisfaction with anesthesia, as well as side effects caused by the…
- Trial name
- BISMAC (NCT03410082)
- Testing
- Titration under the guidance of BIS, Titration under the guidance of OAA/S
- Where
- South Korea
- Volunteers
- 31 people
- Sponsor
- Seoul National University Hospital
Post Anesthesia Care Unit Length of Stay
The Association Between Anesthetic and Surgical Practices and Patient Length of Stay in the Post Anesthesia Care Unit
The investigators are conducting a retrospective, cross-sectional chart review of patients who underwent an anesthetic administered by an anesthesiologist in the University of California Davis main operating rooms and were…
- Trial name
- NCT01826292
- Sponsor
- University of California, Davis
Obstetric Anesthesia Care
Obstetric Anaesthesia And Analgesia Month Attributes - International
A national survey of current practices, preferred drug and technique choices for obstetric anesthesia and analgesia in Czech Republic and Slovak Republic.
- Trial name
- OBAAMA-INT (NCT02380586)
- Testing
- Obstetric anesthesia and analgesia
- Where
- Czechia
- Volunteers
- 3,040 people
- Sponsor
- Brno University Hospital
Myocardial Revascularization, Spinal Anesthesia
Spinal Anesthesia Associated With General Anesthesia in Coronary Artery Bypass
CONTEXT: In patients eligible for coronary artery bypass surgery, anesthesia should provide a number of conditions that exceed the limits of cardiovascular stability, myocardial protection and other organs.
- Conditions
- Myocardial Revascularization, Spinal Anesthesia, Postoperative Care, Fentanyl
- Trial name
- NCT02840006
- Testing
- General anesthesia only, General anesthesia and Spinal anesthesia
- Where
- 2 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- Daniel Gioielli de Castilho
Monitored Anesthesia Care
A Study to Characterize Pharmacokinetics (PK) and Pharmacodynamics (PD) of LUSEDRA® Administered as Continuous Infusion or Bolus Compared With Continuous Infusion of Propofol Injectable Emulsion
The purpose of this study is to explore the pharmacokinetics (PK) and pharmacodynamics (PD) of LUSEDRA® administered as a continuous infusion or bolus compared with continuous infusion of propofol injectable emulsion.
- Trial name
- NCT01308541
- Testing
- arm 1, LUSEDRA, Propofol (arm 3)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Arthroscopic ACL Rerpair, Surgery
Peripheral Nerve Block (Femoral - Sciatic - Obturator) Versus General Anesthesia for Arthroscopic ACL Repair
Arthroscopic ACL repair can be performed under different types of anesthesia. In the last few years peripheral nerve blocks have increased their popularity for this kind of operation.
- Conditions
- Arthroscopic ACL Rerpair, Surgery, Anesthesia Care
- Trial name
- NCT02186899
- Testing
- Ultrasound Guided Femoral Sciatic Obturator nerve blocks, General Anesthesia femoral bolus, General anesthesia femoral continuous
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- Larissa University Hospital