Clinical trials: Anesthesia Complication
Spinal Anesthesia, Postoperative Complications
D-FAB-POUR Trial: Dexmedetomidine vs Fentanyl as Adjuvants to Bupivacaine on Postoperative Urinary Retention
This study aims to compare two medications, dexmedetomidine and fentanyl, when used alongside a commonly used spinal anesthetic called bupivacaine in patients undergoing lower limb surgery.
- Conditions
- Spinal Anesthesia, Postoperative Complications, Dexmedetomidine, Fentanyl
- Trial name
- D-FAB-POUR (NCT07117565)
- Testing
- Intervention 1: Intrathecal Dexmedetomidine with Bupivacaine, Intervention 2: Intrathecal Fentanyl with Bupivacaine
- Where
- Nepal
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Neuromuscular Blockade Reversal Agent, Perioperative Complications
Sugammadex-Induced Clenching During Neuromuscular Blockade Reversal
Study Objective: This study aims to evaluate the incidence, severity, and risk factors of sugammadex-induced mouth clenching during neuromuscular blockade (NMB) reversal in adult surgical patients.
- Conditions
- Neuromuscular Blockade Reversal Agent, Perioperative Complications, Anesthesia, General, Sugammadex
- Trial name
- NCT06962007
- Testing
- Sugammadex 1 mg/kg Group, Sugammadex 2 mg/kg Group, Sugammadex 4 mg/kg Group
- Where
- South Korea
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Postoperative Pain
Total Knee Replacement TIVA With Robotic Arm Assisted
Total knee replacement (TKR) is a commonly performed surgical procedure, and is associated with moderate to severe acute postoperative pain.
- Trial name
- NCT04002271
- Testing
- Propofol, Sevoflurane, Spinal anaesthesia
- Where
- 2 sites in Hong Kong
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Intubation Complication
Nasal Intubation：a Comparison of Different Endotracheal Tubes
Either uses two different endotracheal tubes to pass the nasal cavity and to compare the effects on the secretion and bleeding volume of patients during intubation to facilitate nasotracheal tube advancement.
- Trial name
- NCT05112783
- Testing
- Henan Tuoren Endotracheal Tube, Smiths Portex Tracheal Tubes
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Vitamin D Deficiency
Preoperative Vitamin D Levels and Respiratory Complications of General Anesthesia
Vitamin D deficiency is a commonly observed health problem in the world. With a role in many chronic diseases and especially lung diseases, the importance of vitamin D deficiency in anesthesia management is increased.
- Trial name
- VitaminD (NCT03342651)
- Testing
- Vitamin D
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Ordu University
Emergence Agitation, Pain
Can Acetaminophen Given 1-2 Hours to Children Before Ear Tube Surgery Reduce Agitation After Anesthesia?
Emergence agitation (EA) occurs in up to 67% of pediatric patients after anesthesia for bilateral myringotomy tubes (BMT, "ear tubes").
- Trial name
- NCT01737593
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Postoperative Pain, Mandible Fracture
Postoperative Pain After Bupivacaine Supplementation in Mandibular Fracture Surgery
Pain following open reduction of mandibular fractures is the most reported complaint during the first 24 post-operative hours. The goal of this clinical trial is to evaluate the impact of inferior alveolar nerve block with…
- Conditions
- Postoperative Pain, Mandible Fracture, Analgesia, Anesthesia, Local
- Trial name
- NCT06243263
- Testing
- Bupivacain
- Where
- 2 sites in Tunisia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Pain Threshold, Surgery
The Effect of Remifentanil on the Objectively Measured Pressure Pain Threshold
It is a clinical study investigating the relationship between objectively measured pain threshold and the need for escalating doses of remifentanyl opioids. This study is expected to include approximately 40 participants.
- Conditions
- Pain Threshold, Surgery, Postoperative Pain, Intravenous Anesthesia
- Trial name
- NCT07568405
- Testing
- Pressure pain theshold measured under remifentanil (ultiva®) infusion, Postoperative PCA IV morphine (Sterop®) consumption and adverse events history
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Emergence Agitation
Propofol Versus Dexmedetomidine Effect on Prevention Emergence Agitation
The goal of this clinical trial is to compare Propofol versus Dexmedetomidine in children undergoing squint surgery. The main question it aims to answer is: Which drug is more effective in preventing the appearance of Emergence…
- Trial name
- NCT06312618
- Testing
- Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia, Local, Postoperative Pain
Comparison of Supraclavicular and Costoclavicular Brachial Plexus Blocks in Pediatrics
In upper extremity surgeries, the brachial plexus block can be performed with different techniques at various levels depending on the proximal and distal level of the surgery.
- Trial name
- NCT04782778
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Thoracic Surgery, Low-flow Anesthesia
Effect of Low-Flow Anesthesia in Single Lung Ventilation on Postoperative Respiratory Complications
Mechanical ventilation in thoracic surgery patients is often complicated because patients are usually in the lateral decubitus position and the operated lung is intermittently deflated to facilitate surgical exposure .
- Trial name
- Low-Flow Anest (NCT06838091)
- Testing
- Observational
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Severe Obesity, Hypoxia
Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures
The study evaluated the effect of non-invasive positive pressure ventilation (NIPPV) to decrease the incidence of desaturation events in patients with severe obesity undergoing upper endoscopy.
- Trial name
- NCT03529461
- Testing
- Non-invasive positive pressure ventilation through nasal mask, Rescue non-invasive positive pressure ventilation through nasal mask, Secondary rescue maneuvers
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bristol Hospital
Local Analgesia Via Infiltration, Wound Heal
Comparison of Postoperative Effects of Articaine and Lidocaine in Mucogingival Surgery
The aim of this study is to compare and evaluate the effects of using lidocaine 2% (with adrenaline) and articaine 4% (with adrenaline) in free gingival graft (FGG) surgery on postoperative wound healing, changes in blood flow in…
- Conditions
- Local Analgesia Via Infiltration, Wound Heal, Pain, Postoperative, Hemorrhage
- Trial name
- NCT07145879
- Testing
- Lidocaine hydrochloride 2% with epinephrine 1:100 000, Articaine 4% with epinephrine 1:100,000, Free gingival graft (FGG)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Perioperative Care, EEG Power Spectra
Extended Emergence Strategy on Post-Anesthesia Care Unit Events After Outpatient Orthopedic Surgery
The goal of this clinical trial is to learn if an extended emergence from anesthesia can improve recovery room (Post-Anesthesia Care Unit or PACU) outcomes in lower-leg or foot surgery with nerve blocks.
- Conditions
- Perioperative Care, EEG Power Spectra, Delirium - Postoperative
- Trial name
- PACU-EMERGE (NCT07533370)
- Testing
- Standard of Care EEG-Guided Emergence, Extended EEG Emergence Trajectory
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Harrison Shong-Wen Chow
Scales, Repression-Sensitization, Anesthesia Awareness
Adaptation of Perioperative Satisfaction Scale in Regional Anesthesia and Investigation of Its Psychometric Properties
The aim of the study is to determine the psychometric properties of Perioperative Satisfaction Scale in Regional Anesthesia. In the Turkish version of the scale, a blind reverse translation method will use.
- Trial name
- NCT04009018
- Testing
- Perioperative Satisfaction Scale in Regional Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Ömer Faruk Boran
Anesthesia Intubation Complication, Infant
Evaluation of the Relationship Between Airway Measurements and Laryngoscopic View in Newborn and Infants
Background and Aim: The overall incidence of difficult laryngoscopy in pediatric anesthesia is lower than in adults, but this risk is higher in patients younger than one year of age.
- Conditions
- Anesthesia Intubation Complication, Infant, Newborn
- Trial name
- NCT03920748
- Testing
- Group D, Group E
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ankara Children's Health and Diseases Hematology and Oncology Training and Research Hospital
Post Operative Pulmonary Complications, Neuromuscular Blockade
Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease
The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients with chronic kidney disease.
- Conditions
- Post Operative Pulmonary Complications, Neuromuscular Blockade, General Anesthesia
- Trial name
- NCT07203287
- Testing
- Rocuronium, Cisatracurium, Sugammadex
- Where
- United States
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Emergence Delirium, Anesthesia
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Emergence delirium (ED) was first described by Eckenhoff and colleagues in the 1960s and is defined in pediatric anesthesia as 'dissociated state of consciousness in which child is irritable, uncompromising, uncooperative…
- Trial name
- NCT07057193
- Testing
- Dexmedetomidine group (D group), Ketamine group (K group), Midazolam group (M group)
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Pain
Effect of Noise Blocking During General Anesthesia on Postoperative Pain
To investigate the effect of noise blocking during general anesthesia on postoperative pain in patients undergoing laparoscopic abdominal surgery.
- Trial name
- NCT05540691
- Testing
- Wear noise-cancelling earphones
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Hemodynamic Stability, Post Operative Pain
Comparative Efficacy & Safety of Dexmedetomidine vs Tramadol in Paeds Hernioraphy. A Caudal Anaesthesia Approach
Among the postoperative adverse effects, pain has significant importance. Caudal block is a common technique for pediatric analgesia for infraumbilical surgeries.
- Conditions
- Hemodynamic Stability, Post Operative Pain, Inguinal Hernia Repair
- Trial name
- NCT06735443
- Testing
- Bupivacaine with Dexmetedomidine, Bupivacaine with Tramadol
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal