Clinical trials: Anesthesia Complication
Airway Complication of Anaesthesia, Healthy
The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects
The investigators hypothesize that propofol, when compared to sevoflurane, causes the upper airway to collapse more easily and causes less activity in the tongue muscle.
- Trial name
- NCT01557920
- Testing
- Propofol, Sevoflurane
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Secretion Removal Above ETT Cuff
Evaluation of Above the Cuff Suctioning During General Anesthesia
The aim of this prospective, randomized, pilot study is compare ease of tracheal intubation, amount of microaspiration and efficacy of secretion removal using three FDA (Food and Drug Administration)-cleared endotracheal tubes…
- Trial name
- NCT01386879
- Testing
- methylene blue
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thomas Jefferson University
Opioid Use, Unspecified
the Analgesic Duration of Dexmedetomidine Compared to Dexamethasone as Adjuncts to Single Shot Interscalene Block
The purpose of the study is to determine if perineural dexmedetomidine can provide increased prolongation of analgesia when compared to perineural dexamethasone in patients receiving regional block for shoulder surgery.
- Trial name
- NCT02653144
- Testing
- Ropivacaine, Dexmedetomidine, Dexamethasone
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Montefiore Medical Center
Nephrolithiasis, Urolithiasis
Perioperative Pregabalin in Ureteroscopy: a Pilot
The investigators propose a pilot clinical trial on the use of perioperative pregabalin in order to decrease ureteral stent related symptoms and decrease opioid usage after ureteroscopy with stent placement.
- Conditions
- Nephrolithiasis, Urolithiasis, Perioperative/Postoperative Complications, Pain, Postoperative
- Trial name
- NCT03927781
- Testing
- Pregabalin 300mg
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Anesthesia Intubation Complication
Comparison of Flexible Fibreoptic Scope With Pentax AWS Videolaryngoscope for Ease of Intubation During Awake Intubation
The purpose of this study is to identify whether Pentax Airway Scope (AWS) videolaryngoscope would be a more effective device compared to flexible fibreoptic scope (FOS) for awake intubation in a difficult airway.
- Trial name
- NCT02614924
- Testing
- Flexible fibreoptic scope, Pentax AWS videolaryngoscope
- Volunteers
- 40 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Anesthesia, Pain
Combined Spinal Epidural Urinary Retention
The investigators hypothesize that many parturients can, in fact, spontaneously micturate with low dose combined spinal epidural analgesic doses given for labor and that Foley catheterization is unnecessary in the majority of…
- Conditions
- Anesthesia, Pain, Urinary Retention
- Trial name
- NCT01597791
- Testing
- Foley catheter, No foley catheter
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Northwestern University
Pain, Postoperative
Intrathecal Paracetamol Before Spinal Anaesthesia With Chloroprocaine HCl 1% for Short Knee Procedures
This is a phase II, single centre, randomised, parallel-group, double-blind, three doses, placebo-controlled, exploratory efficacy and safety study.
- Trial name
- NCT03428230
- Testing
- 30 mg Paracetamol 3% (1 mL), 60 mg Paracetamol 3% (2 mL), 90 mg Paracetamol 3% (3 mL)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Sintetica SA
Post-operative Pain
A Trial Assessing The Association Between Type Of Local Anesthesia Treatment And Postoperative Pain In Patients In Having Undergone Arrhythmia Surgery
The goal of the proposed study is to investigate the relationship between two standard treatments, lidocaine or a mixture of lidocaine and bupivacaine, and 1) postoperative pain, and; 2) narcotic use following pacemaker or…
- Trial name
- NCT01300377
- Testing
- Bupivacaine / Lidocaine, Lidocaine
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Baylor Research Institute
Intraoperative Complications, Postoperative Complications
Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.
The goal of this study is to investigate the effect of depth of neuromuscular block (NMB) on global and regional (dependent versus nondependent) respiratory mechanics during laparoscopic surgery.
- Conditions
- Intraoperative Complications, Postoperative Complications, Laparoscopy, Surgical Complications From General Anesthesia
- Trial name
- NCT02025075
- Testing
- Rocuronium
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Postoperative Atelectasis, Postoperative Hypoxemia
REMINDers for Incentive Spirometry in PACU (REMIND-IS in PACU)
The purpose of this study is to determine if the frequency of use of incentive spirometry during the stay in the Post-Anesthesia Care Unit (PACU) increases with visual and auditory electronic reminders, as compared to not having…
- Conditions
- Postoperative Atelectasis, Postoperative Hypoxemia, Postoperative Pneumonia, Postoperative Pulmonary Complications
- Trial name
- NCT06304493
- Testing
- Alarms
- Where
- United States
- Volunteers
- 231 people
- Sponsor
- University of Colorado, Denver
Residual Neuromuscular Blockade
Electromyographic and Acceleromyographic Monitoring in Restricted Arm Movement Surgical Setting
Researchers are comparing the ease of use and repeatability of the force vs electrical activity produced by a muscle after it has undergone nerve stimulation during a surgical procedure in which the patients' arm movement is…
- Trial name
- NCT04352140
- Testing
- Tetragraph, ToFscan
- Where
- 3 sites in United States, France and 1 more
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Analgesia Disorder, Anesthetic Complication Epidural
Effectiveness of Epidural Anesthesia for Thoracic and Abdominal Surgery
This study aims to evaluate the effectiveness of the epidural analgesia in patients having elective thoracic and abdominal surgery under general anesthesia combined with epidural analgesia in Siriraj Hospital.
- Conditions
- Analgesia Disorder, Anesthetic Complication Epidural, Adverse Reaction to Epidural Anesthesia
- Trial name
- NCT02315261
- Testing
- Elective Thoracic and Abdominal Surgery Patients
- Where
- Thailand
- Volunteers
- 364 people
- Sponsor
- Siriraj Hospital
Postoperative Pain, Surgery
Local Anesthesia Versus Saline Serum in Surgical Incision of Colorectal or Hepatic Surgery
The purpose of this study is to determine whether a continuous infusion of local anesthesia with a catheter in the surgical wound reduces patient consumption of opiates by 30% in the 48-hour postoperative period following surgery…
- Conditions
- Postoperative Pain, Surgery, Postoperative Complications
- Trial name
- CATROP-2007 (NCT01075646)
- Testing
- ropivacaine, saline solution
- Where
- Spain
- Volunteers
- 225 people
- Sponsor
- Hospital Universitari de Bellvitge
Airway Complication of Anesthesia
Observational Study of the LMA Protector
The investigators want to investigate the user friendliness, and performance of the LMA Protector. The principal research question is to assess the overall performance of the LMA Protector.
- Trial name
- ADEPT1 (NCT03664700)
- Testing
- LMA Protector
- Where
- 5 sites in United Kingdom
- Volunteers
- 112 people
- Sponsor
- Oxford University Hospitals NHS Trust
Bladder Cancer
Comparison of Nerve Stimulating Approach and Interfascial Injection Approach During Sono-guided Obturator Nerve Block
Transurethral resection of bladder tumor (TURB) has been essential treatment for bladder tumours. Direct electrical stimulation of an obturator nerve during the TURB procedures can trigger an inadvertent adductor muscle spasm…
- Trial name
- NCT02452944
- Testing
- nerve stimulator (stimuplex HNS12), ultrasound
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Gachon University Gil Medical Center
Pain, Postoperative
Exparel vs. Standard Bupivicaine for Abdominoplasty
Background \& study question: Strategies for post-operative pain control that make use of various different types of medicines are advantageous both for patient comfort and for minimizing the use of opioid pain medicines and…
- Trial name
- NCT01853176
- Testing
- Liposomal Injection Bupivacaine (Exparel), Standard bupivicaine
- Where
- 3 sites in United States
- Volunteers
- 4 people
- Sponsor
- Emory University
Emergence Delirium
Emergence Agitation Between Dexmedetomidine and Sevoflurane Anesthesia
Emergence agitation is commonly encountered after receiving inhalation anesthesia. This distressing phenomenon carries risks that are harmful to patients, caregivers and medical personnel.
- Trial name
- NCT06482125
- Testing
- Dexmedetomidine, Sevoflurane
- Where
- Indonesia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Pelita Harapan University
Residual Neuromuscular Blockade
Cardiac Output and Recovery Time
The purpose of this research is to determine the time it takes to reverse the effects of the intraoperative medication given to relax the muscles and how this period of recovery correlates with a function of the heart.
- Trial name
- NCT04619225
- Testing
- TetraGraph
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Mayo Clinic
Residual Neuromuscular Blockade
Thumb vs Great Toe Recovery
Researches are comparing the accuracy of measuring muscle relaxation in the thumb versus the great toe.
- Trial name
- NCT04312256
- Testing
- TetraGraph
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Mayo Clinic
Anaesthesia
Effect of Laryngeal Mask Cuff Pressure in Geriatric Patients
Laryngeal Mask is widely used for air-way management during anaesthesia. Pharyngolaryngeal morbidity linked to laryngeal mask use is related to correct choice of mask size, placement technique, placement of the laryngeal mask in…
- Trial name
- NCT02189954
- Testing
- The placement according to the manufacturer's instructions, Cuff inner pressure was held below 44 mmHg
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dokuz Eylul University