Clinical trials: Anesthesia Complication
Anesthesia, Nerve Block
Comparison of the Effect of Preoperative and Postoperative ESP and PVB on Postoperative Pain in VATS
The aim of this prospective controlled randomised clinical trial was to identify the analgesic method that is more effective than two different regional analgesia techniques routinely used for pain control after video-assisted…
- Conditions
- Anesthesia, Nerve Block, Pain, Postoperative, Thoracic Surgery, Video Assisted
- Trial name
- NCT06488014
- Testing
- Erector spina plan block (ESP), Paravertebral block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara University
Residual Neuromuscular Blockade, Residual Paralysis, Post-Anesthesia
Incidence of Postoperative Residual Neuromuscular Blockade in Portugal
This is an epidemiological multicenter, observational, prospective study, designed to determine the incidence of postoperative residual neuromuscular blockade - defined by a TOF (train-of-four) ratio < 0.9 - at PACU arrival.
- Conditions
- Residual Neuromuscular Blockade, Residual Paralysis, Post-Anesthesia, Observational Study, Complication of Anesthesia
- Trial name
- NCT03417804
- Where
- 10 sites in Portugal
- Volunteers
- 366 people
- Sponsor
- Centro Hospitalar do Porto
Urinary Stress Incontinence
Safety and Efficacy Study on the Implantation of the Tension-Free Vaginal Tape (TVT-Secur) Under Local Anesthesia
The objective was to observe the satisfaction of local anesthesia during the implantation of the TVT-SECUR for the treatment of stress urinary incontinence, with the use of questionnaires completed by the patients, and to…
- Trial name
- NCT00904618
- Testing
- TVT-SECUR - 'Hammock' technique, TVT-SECUR - 'U-Method', Local anesthesia (30 to 40 ml of a mixture of 35 ml of lidocaine 2% and 5 ml of bicarbonate 3%).
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Université de Sherbrooke
Anesthesia Intubation Complication
Tracheal Palpation of Sliding Cuff to Assess Endotracheal Tube Location
Correct endotracheal tube (ETT) placement is important. Proper ETT position is achieved when the distal tip is in mid-trachea with the head in neutral alignment.
- Trial name
- NCT02502461
- Testing
- cuff palpation
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Saskatchewan
Pain, Postoperative
Block and Periarticular Injection Study
The purpose of the study is to compare two types of perioperative analgesic modalities, adductor canal block plus interspace between popliteal artery and capsule of the knee (IPACK) block and periarticular injection versus…
- Trial name
- NCT06410612
- Testing
- regional anesthesia and PAI, PAI
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Washington University School of Medicine
Hypotension During Surgery, Blood Loss, Surgical
Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery
This prospective study will analyze the need for deliberate hypotensive anesthesia (DHA) during orthognathic surgery when tranexamic acid (TXA) is administered.
- Trial name
- NCT05474027
- Testing
- Avoidance of Deliberate Hypotensive Anesthesia, TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Residual Neuromuscular Blockade
Comparison of the ToFscan and TetraGraph During Recovery of Neuromuscular Function in the Post Anesthesia Care Unit
The aim of this investigation is to compare the performance of two quantitative monitors utilized on post-anesthesia recovering patients.
- Trial name
- NCT03920670
- Testing
- TetraGraph (TG), ToFscan (TS)
- Where
- 3 sites in United States, Hungary
- Volunteers
- 120 people
- Sponsor
- Mayo Clinic
Intraoperative Complications, Postoperative Complications
Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.
The goal of this study is to investigate the effect of depth of neuromuscular block (NMB) on global and regional (dependent versus nondependent) respiratory mechanics during laparoscopic surgery.
- Conditions
- Intraoperative Complications, Postoperative Complications, Laparoscopy, Surgical Complications From General Anesthesia
- Trial name
- NCT02025075
- Testing
- Rocuronium
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Postoperative Nausea and Vomiting
Aprepitant for PONV Prophylaxis in Outpatient Plastic Surgery
Hypothesis: Aprepitant plus ondansetron is more effective than ondansetron plus placebo for prevention of postoperative emesis in patients at moderate-to-high risk for PONV for up to 48 hours after surgery.
- Trial name
- NCT00659945
- Testing
- Aprepitant plus Ondansetron
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Postoperative Pain
Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management
To evaluate the efficacy of bilateral continuous erector spinae blocks (BESB) for postoperative analgesia in children and adolescents undergoing cardiac surgical procedures via sternotomy in the Early Recovery After Surgery…
- Trial name
- NCT04567407
- Testing
- Bilateral erector spinae blocks using ropivacaine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Alzheimers Disease, Postoperative Delirium
Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care
This study will examine the hypothesis that changes in the cognition (i.e. thinking and memory) after anesthesia and surgery are correlated with changes in markers of Alzheimers Disease in the fluid around the brain and spinal…
- Conditions
- Alzheimers Disease, Postoperative Delirium, Post Operative Cognitive Dysfunction
- Trial name
- MADCO-PC (NCT01993836)
- Testing
- Total intravenous anesthesia with propofol, General anesthesia with isoflurane
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Duke University
Surgery--Complications
Pilot Study for Postoperative Machine Learning
The objectives of the study are to determine the interpretability, workflow role, and effect on communications of showing report cards containing Machine Learning (ML)-based risk profiles based on pre- and intra-operative data to…
- Trial name
- NCT04877535
- Testing
- ML-based report card
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Washington University School of Medicine
Emergence Delirium, Anesthesia Emergence Delirium
Effect of Monochromatic Light on Incidence of Emergence Delirium in Children
Emergence delirium/emergence agitation (ED/EA) is a behavioral phenomenon of unclear etiology consisting of short lived behavioral changes that can be both traumatic to families and pose a safety risk to patients and staff.
- Trial name
- NCT03285243
- Testing
- Monochromatic blue light
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Airway Complication of Anesthesia
Observational Study of the LMA Protector
The investigators want to investigate the user friendliness, and performance of the LMA Protector. The principal research question is to assess the overall performance of the LMA Protector.
- Trial name
- ADEPT1 (NCT03664700)
- Testing
- LMA Protector
- Where
- 5 sites in United Kingdom
- Volunteers
- 112 people
- Sponsor
- Oxford University Hospitals NHS Trust
Intubation Complication
Suction Catheter as a Guide for Nasotracheal Intubation Under General Anesthesia
The goal of this clinical trial to study the efficacy of suction catheter guided technique and conventional technique during nasotracheal intubation.
- Trial name
- NCT05717907
- Testing
- suction catheter
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Mahidol University
Anaesthesia
General Anesthesia With Xenon in Inspiratory Concentrations of 50% and 70% and Total I.V. Anaesthesia.
The purpose of this study is to evaluate the quantity of propofol administered with Xenon in two inspiratory concentrations, to maintain comparable depth of anaesthesia during the maintenance period of general anaesthesia.
- Trial name
- NCT00919126
- Testing
- Xenon, Medical Air in Oxygen
- Where
- 6 sites in France, Germany and 1 more
- Volunteers
- 102 people
- Sponsor
- Air Liquide SA
Postoperative Pain
A Pain Study Comparing Two Commonly Used Medications to Treat Pain After Bowel Surgery
This research study is testing whether the local anesthetic lidocaine is as effective as ropivacaine for post-operative pain control in continuous thoracic paravertebral nerve blocks.
- Trial name
- NCT02849678
- Testing
- Ropivacaine, Lidocaine
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Jacques E. Chelly
Analgesia Disorder, Anesthetic Complication Epidural
Effectiveness of Epidural Anesthesia for Thoracic and Abdominal Surgery
This study aims to evaluate the effectiveness of the epidural analgesia in patients having elective thoracic and abdominal surgery under general anesthesia combined with epidural analgesia in Siriraj Hospital.
- Conditions
- Analgesia Disorder, Anesthetic Complication Epidural, Adverse Reaction to Epidural Anesthesia
- Trial name
- NCT02315261
- Testing
- Elective Thoracic and Abdominal Surgery Patients
- Where
- Thailand
- Volunteers
- 364 people
- Sponsor
- Siriraj Hospital