Clinical trials: Anesthesia Conduction
Pain, Postoperative
Comparison of Local Anesthetic Dose in PENG Block Performed in Total Hip Replacement Operations
The investigators research was designed as a single-center, prospective, randomized double-blind study. The patients undergoing total hip replacement surgery in Istanbul University Istanbul Medicine Faculty Department of…
- Trial name
- NCT04900116
- Testing
- Bupivacaine HCl 0.5 % in 20 ML Injection, Bupivacaine HCl 0.25 % in 20 ML Injection, Bupivacaine HCl 0.125 % in 20 ML Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Postoperative Pain, Anesthesia, Conduction
PANDA-Regional Feasibility Study of a Smartphone Pain Management Application
Despite the numerous benefits of peripheral nerve blocks (PNBs) over general anesthesia (GA) in a variety of surgical procedures, PNBs can be associated with increased post-operative pain if pain medications are not taken…
- Trial name
- NCT03369392
- Testing
- Panda application
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anesthesia, Local
The CIA Score: a Learner's Tool
The goal of this project is to use a previously described scoring system - the CIA system - as a teaching tool to help learners assess the bleeding risk of peripheral nerve blocks.
- Trial name
- NCT05153265
- Testing
- Survey
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Stanford University
Post Operative Pain, Regional Anesthesia Morbidity
Does ESP Block Reduce Pain and Opiates Consumption After Surgery
The patients will be randomly assigned to standard therapy or standard therapy+ESP nerve block. After surgery pain level and narcotic consumption will be measured, and vital signs and side effects will bo monitored for up to 72…
- Conditions
- Post Operative Pain, Regional Anesthesia Morbidity, Opioid-Related Disorders, Chronic Pain
- Trial name
- NCT05512897
- Testing
- erector spinea plane block
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Michael Dubilet MD
Anesthesia, Anesthesia, Local
A Study in Healthy Male Volunteers to Investigate the Safety and Tolerability of a Single Dose of Neosaxitoxin Alone and in Combination With Bupivacaine (With and Without Epinephrine) for Brachial Plexus Blockade
Neosaxitoxin is a new compound that is in clinical development as local anesthetic for surgical anesthesia and postoperative analgesia.
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia
- Trial name
- NCT03399435
- Testing
- Neosaxitoxin combined with bupivacaine low and epinephrine (T1), Bupivacaine low combined with epinephrine (C1), Bupivacaine high combined with epinephrine (C2)
- Where
- Netherlands
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Ultrasound Imaging of Anatomical Structures
Validity of Experts and ScanNav Anatomy PNB When Identifying Sono-anatomical Structures for Ultrasound-Guided Regional Anaesthesia
This is a multi-centre, prospective, observational study, conducted under the auspices of the University of Oxford to evaluate ultrasound image analysis by human experts and an artificial intelligence device in the context of…
- Trial name
- NCT04983771
- Testing
- Annotate ultrasound scans
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- IntelligentUltrasound Limited
Shoulder Pain, Supraspinatus Tendinitis
MINIMUM EFFECTIVE VOLUME OF BUPIVACAİNE FOR ANTERIOR SUPRASCAPULAR NERVE BLOCK
Various local anesthetic volumes are used in the literature for anterior suprascapular nerve block (ASSB). There are different studies between 15 ml and 5 ml.
- Conditions
- Shoulder Pain, Supraspinatus Tendinitis, Bankart Lesions
- Trial name
- NCT05241977
- Testing
- anterior supra scapular nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- V.K.V. American Hospital, Istanbul
Regional Anesthesia, Horner Syndrome
Cerebral Blood Flow Evaluation With Trancranial Doppler After Interscalene Nerve Block
The purpose of this study is to assess cerebral blood flow velocity (CBFV) following regional anesthesia for shoulder surgery. The results of this study will help to further understand the physiologic effect of the interscalene…
- Conditions
- Regional Anesthesia, Horner Syndrome, Cerebral Blood Flow
- Trial name
- CBF-TCD (NCT04642612)
- Testing
- TCD Measurement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stanford University
Compartment Syndrome of Leg, Healthy
Detecting Compartment Syndrome Pain in the Presence of Regional Anesthesia in Healthy Volunteers
The goal of the study is to determine how different types of Regional Anesthesia (nerve blocks) can be helpful to patients with lower extremity trauma who develop compartment syndrome (an increased pressure in the fascial…
- Trial name
- NCT04113954
- Testing
- Mepivacaine Injection
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Thoracic Diseases, Thoracic Surgery
Deep Serratus Anterior Plane Block vs Surgically-placed Paravertebral Block for VATS Surgery
Thoracic surgery, and surgery involving the chest wall in general, is associated with poorly controlled acute pain, which may result in delayed functional recovery, and may progress to chronic pain.
- Conditions
- Thoracic Diseases, Thoracic Surgery, Rib Fractures, Pain, Postoperative
- Trial name
- SAPB (NCT03768193)
- Testing
- Deep serratus anterior plane block, Surgically-placed paravertebral block
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mater Misericordiae University Hospital
Neuraxial Technique
Accuracy of the Accuro 3S
The main purpose of this study is to evaluate the feasibility and accuracy of the Accuro 3S to provide live guidance when performing a neuraxial technique (e.g., spinal, or epidural).
- Trial name
- NCT07458087
- Testing
- ACCURO 3S
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yale University
Regional Anesthesia Morbidity
Assessing Current Peripheral Nerve Block Catheter Fixation and Dressing Strategies: An Equivalence Study
The investigators' objective is to evaluate whether any of the various peripheral nerve block catheter dressing strategies currently employed by the Boston Children's Hospital Regional Anesthesia Service has any differential…
- Trial name
- NCT02926521
- Testing
- 2-octyl cyanoacrylate, Gum Mastic
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Anesthesia, Local
Does Perineural Dexamethasone Increase the Duration of an Ulnar Nerve Block When Controlling for Systemic Effects?
Investigators will assess if perineural dexamethasone can increase the duration of an ulnar nerve block when controlling for systemic effects in healthy volunteers.
- Trial name
- NCT04817982
- Testing
- Perineural dexamethasone, Lidocaine, Systemic dexamethasone
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Hand Injury, Wrist Injury
Comparing Two Injection Sites of Local Anesthetic for Hand Surgery
The purpose of this study is to compare two different injection sites for local anesthesia in patients having hand surgery. The hypothesis is that subjects receiving injections around the three nerves of the forearm will provide…
- Conditions
- Hand Injury, Wrist Injury, Finger Injury
- Trial name
- NCT02112006
- Testing
- 0.5% bupivacaine injected in the forearm, 20-30ml of 0.5% bupivacaine.
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Pacemaker, Artificial
A Pilot Study on Pacemaker Interference From Peripheral Nerve Stimulator for Regional Anesthesia
In this prospective pilot study, we proposed to evaluate the effects of left interscalene stimulation on cardiac pacemaker function.
- Trial name
- NCT00586248
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Patient Safety, Anesthesia
Impact of Production Pressure in the Block Room on Patient Safety
This randomized, single blinded simulation based study investigates the impact that production pressure can have on the safety of patients undergoing regional anesthesia.
- Trial name
- NCT04846660
- Testing
- Production pressure
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Venomous Snakebites, Local Anesthesia
Subcutaneous Injection of Large Volumes of Tumescent Lidocaine and Epinephrine by Laypersons
This research is intended to show that it is safe and not difficult for nearly anyone to inject at least 125ml of a dilute solution of tumescent lidocaine and epinephrine (TLE), where a TLE solution consists of lidocaine (1gm/L)…
- Conditions
- Venomous Snakebites, Local Anesthesia, Painless Injection, Regional Anesthesia
- Trial name
- TLE-RCT (NCT04733781)
- Testing
- Tumescent Lidocaine and Epinephrine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Jeffrey Alan Klein, MD
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery
One technique for the nerve block involves injecting the numbing medicine where the nerve is together (higher up in the back of the thigh).
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot
- Trial name
- NCT01550094
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Saphenous Nerve Block
Saphenous Nerve Block for Foot and Ankle Surgery
Patients undergoing foot and ankle surgery have the option of having a nerve block administered by their Anesthesiologist. The nerve block numbs the foot and results in less post-operative nausea and vomiting, and better pain…
- Trial name
- NCT02382744
- Testing
- Ultrasound Guidance, Ultrasound guidance + nerve stimulation
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
PONV, Regional Anaesthesia
Incidence and Factors Associated With PONV in Regional Anaesthesia
Post-operative nausea and vomiting (PONV) is one of the complications associated with surgery and anaesthesia. The main aim of the study is to determine the incidence of post-operative nausea and vomiting among surgical patients…
- Trial name
- NCT03835234
- Where
- Uganda
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Makerere University