Clinical trials: Anesthesia Depth Monitoring, open to volunteers
Awareness During General Anesthesia
Is Density Spectral Array Display Along With Bispectral Index Superior to the Display of Bispectral Index Alone
A study to evaluate the use of density spectral array display in comparison with Bispectral index in a clinical setting.
- Trial name
- DSA-Light (NCT07232160)
- Testing
- Depth of anesthesia monitoring using processed EEG
- Where
- Australia
- Volunteers
- 70 people
- Sponsor
- The University of Queensland
Surgical Stress Response, Inflammation
CoreSys Monitoring for Intraoperative Stress Management in Abdominal Hysterectomy
This randomized controlled trial evaluates whether intraoperative guidance using the CoreSys monitor reduces the surgical stress response in patients undergoing elective open abdominal hysterectomy.
- Conditions
- Surgical Stress Response, Inflammation, Anesthesia, Perioperative Care
- Trial name
- CORESTRESS (NCT07571473)
- Testing
- propofol, CoreSys Monitor, Remifentanil (Target-Controlled Infusion)
- Where
- Argentina
- Volunteers
- 30 people
- Sponsor
- Hospital Provincial de Rosario
Depth of Anesthesia, Nociception
Anesthesia Induction Scheme for Painless Gastrointestinal Endoscopy Patients Based on Nociceptive Stimulation Monitoring
Nociception is the encoding and processing of noxious stimulation and is considered an objective indicator for monitoring pain. Currently, a new clinically-applied medical-engineering integrated monitoring device for noxious…
- Conditions
- Depth of Anesthesia, Nociception, Painless Gastrointestinal Endoscopy
- Trial name
- NCT06604156
- Testing
- EEG monitoring
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Min Su
Cognitive Impairment, Cognitive Impairment, Mild
Cognitive Assessment And Post-Operative Complications After Surgery: Linking Anaesthesia And Risk
Many older people can experience confusion, memory problems, or a decline in their thinking after major surgery. These problems are sometimes called 'postoperative neurocognitive disorders' or PND and can affect recovery and a…
- Conditions
- Cognitive Impairment, Cognitive Impairment, Mild, Cognitive Impairment, Progressive, Anesthesia
- Trial name
- CAPSULAR (NCT07470216)
- Testing
- Montreal Cognitive Assessment, biomarkers
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Aging, Inflammation
Macrophage/Monocyte Driven Inflammation and Anesthetic Sensitivity in Aging
The goal of this observational study is to determine whether macrophage/monocyte mediated inflammatory signaling contributes to reduced anesthetic requirements in older adults undergoing major abdominal surgery.
- Conditions
- Aging, Inflammation, Blood-Brain Barrier Permeability, Anesthesia Brain Monitor
- Trial name
- MACRO-AGE (NCT07372417)
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University of Chile
Anesthesia, Intubation, Endotracheal
Patient State Index at Laryngoscopy and Tracheal Intubation Conditions
The goal of this observational study is to learn whether the depth of anesthesia at the moment the breathing tube is placed is related to how easily the tube can be placed, in adult women (18 to 65 years) having planned surgery…
- Conditions
- Anesthesia, Intubation, Endotracheal, Anesthesia Depth Monitoring
- Trial name
- NCT07864402
- Testing
- Depth of anesthesia at laryngoscopy (Patient State Index)
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people
- Sponsor
- Sakarya University
Geriatric Patient Care Improvement, Postoperative Delirium (POD)
The Effects of Anesthesia Depth Monitoring on Postoperative Recovery and Cognitive Functions in the Geriatric Patient Population
This study will be conducted on patients aged 65 and older scheduled for surgery due to lumbar or cervical disc herniation. General anesthesia is routinely used for these types of surgeries in the hospital.
- Conditions
- Geriatric Patient Care Improvement, Postoperative Delirium (POD), Burst Suppression
- Trial name
- NCT06844279
- Testing
- Control Group: Standard Hemodynamic Monitoring, Processed Electroencephalogram (BIS Index), Processed Electroencephalogram (DSA Mode)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Aslıhan Güleç
Brain Tumor Adult, Processed EEG
Processed EEG for Monitoring of Anesthetic Depth in Intracranial Tumor Surgery
An important feature of neurosurgical anesthesia is early postoperative recovery of consciousness with minimal residual sedation.
- Conditions
- Brain Tumor Adult, Processed EEG, Total Intravenous Anesthesia
- Trial name
- NCT06922500
- Testing
- depth of anesthesia
- Where
- Sweden
- Volunteers
- 126 people
- Sponsor
- Region Skane
Anesthesia, Behavior Change
pEEG-Guided Anesthesia and Behavioral Outcomes in Children
Post-hospitalization behavioral changes are common in children after surgery and general anesthesia and may persist for varying durations depending on individual and perioperative factors.
- Conditions
- Anesthesia, Behavior Change, Behavior Child Problems, Anesthesia Depth Monitoring
- Trial name
- NCT07473024
- Testing
- Processed EEG Monitoring, Standard Anesthesia Management
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Istanbul University
Spinal (Fusion) Surgery, Total Intravenous Anesthesia
Comparison of Hemodynamic Responses During Anesthesia Induction Using Eleveld and Schnider
This randomized prospective study aims to compare the effects of two target-controlled infusion models, the Schnider and Eleveld models, on anesthetic depth and hemodynamic responses during anesthesia induction in adult patients…
- Conditions
- Spinal (Fusion) Surgery, Total Intravenous Anesthesia, Target Controlled Infusion of Propofol, Anesthesia Depth Monitoring
- Trial name
- NCT07586189
- Testing
- TCI Propofol Injection Models- Eleveld, TCI Propofol Injection Schnider
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Nociception
Quantitative Consciousness Index Monitoring (qNOX) of Sedation During Endoscopy
Nociception is the encoding and processing of noxious stimulation and is considered an objective indicator for monitoring pain. Currently, a new clinically-applied medical-engineering integrated monitoring device for noxious…
- Trial name
- NCT06777589
- Testing
- Monitoring of anesthesia depth
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Min Su
Depth of Anesthesia Monitoring, BIS-EEG
The Effects of Midazolam, Dexmedetomidine, and Esketamine on Bispectral Index and Raw Electroencephalogram in Patients Under Propofol-Remifentanil Baseline Anesthesia
This prospective, single-center, randomized interventional study aims to investigate the effects of commonly used adjunct anesthetic drugs on the Bispectral Index (BIS) and electroencephalographic (EEG) activity during total…
- Trial name
- NCT07699523
- Testing
- Midazolam, Dexmedetomidine, Esketamine
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- China-Japan Friendship Hospital
Heart Disease
Assessment of Cardiac Function and Anesthesia Depth in Patients Undergoing Cardiac Surgery
The SHAPE study is a prospective, randomized study evaluating changes in cardiac function in adult patients undergoing cardiac surgery with cardiopulmonary bypass.
- Trial name
- SHAPE (NCT07770269)
- Testing
- BIS-guided anesthesia: BIS 45-55, BIS-guided anesthesia: BIS 30-35
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- AHEPA University Hospital
Laparoscopic Hysterectomy
Effect of Trendelenburg Position on Patient State Index
The goal of this observational study is to evaluate whether the Trendelenburg position affects electroencephalography-based depth of anesthesia monitoring and cerebral oxygenation during general anesthesia.
- Trial name
- NCT07467200
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Anesthesia
Research on Anesthesia Depth Control Strategy Based on Continuous and Non-invasive Monitoring of Exhaled Breath
This study aims to propose a strategy for controlling the depth of anesthesia based on continuous and non-invasive monitoring of exhaled breath: BIS value during intravenous-inhalation combined anesthesia is predicted according…
- Trial name
- NCT07272044
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Laryngoscopy, Child
Correlation Between Sedation Depth Monitoring and Reflexes During Intravenous Anesthesia With Dexmedetomidine and Remifentanil in Children Undergoing Direct Laryngoscopy for Surgical Procedures
This study evaluates the correlation between sedation depth monitoring obtained by NeuroSENSE ® NS 701 Monitor and reflexes during intravenous anesthesia in children undergoing direct laryngoscopy for surgical procedures.
- Conditions
- Laryngoscopy, Child, Monitoring
- Trial name
- NCT03426579
- Testing
- NeuroSENSE ®in children
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- University Hospital, Antwerp
Monitoring of Depth of Anesthesia
Patient Positioning and Its Influence on BIS, NOL, and Cerebral Oxygenation in Anesthetized Patients
The goal of this observational study is to find out how changes in body position during surgery might affect brain monitoring results in patients who are under general anesthesia.The main question it aims to answer is: Does…
- Trial name
- NCT07013734
- Volunteers
- 71 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
General Anesthesia-Induced Altered Consciousness
Brain Activity and Changes in Consciousness During General Anesthesia
This study aims to investigate how general anesthetics alter brain activity and consciousness across different age groups. The study will evaluate four anesthetic agents with different mechanisms of action: propofol, remimazolam…
- Trial name
- NCT07836205
- Testing
- Propofol (Group P), Remimazolam group, Esketamine group
- Where
- China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Thyroid Surgeries, Intraoperative Analgesic Use
qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery
The aim of this study is to evaluate the effect of using the non-invasive Conox monitor on intraoperative opioid consumption. Additionally, the study aims to assess the impact of Conox monitoring on recovery time, postoperative…
- Conditions
- Thyroid Surgeries, Intraoperative Analgesic Use, Anesthesia Depth Monitoring
- Trial name
- NCT07445659
- Testing
- Connox EEG Monitoring, standard anesthesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Anaesthesia, Anesthesia Depth Monitoring
Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients
Perioperative assessment of adequate depth of anesthesia and analgesia is currently a recommended part of routine anesthesia practice for all surgical procedures.
- Trial name
- ANIGAPP (NCT07245654)
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital