Clinical trials: Anesthesia Effectiveness
Morbid Obesity
Apneic Oxygenation for Morbid Obese Parturient in cs
The aim of this study is to compare the effect of apneic preoxygenation to conventional preoxygenation on the oxygen desaturation in morbid obese parturient performing elective caesarean section under general anesthesia.
- Trial name
- NCT05021549
- Testing
- nasal prong
- Where
- 2 sites in Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain
Comparison Between the Analgesic Effectiveness of Virtual Reality and Topical Anesthesia: A Clinical Study
A split-mouth, controlled trial aimed to clinically compare and evaluate the effectiveness of virtual reality versus topical anesthesia gel prior to administration of dental anesthesia injection in reducing the perceived pain and…
- Trial name
- NCT04919421
- Testing
- Dental injection and topical gel application, Dental injection and virtual reality device
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Anesthesia Effectiveness
Pain Perception During Inferior Alveolar Nerve Block Administration in Children Using Vibraject and Dental Vibe Versus Conventional Syringe
This RCT study aims to establish evidence based decision comparing between Vibraject (MiltexInc LLC.,York,PA,USA).and Dental vibe(BING Innovations LLC,Crystal Lake,IL,USA versus Conventional Syringe on pain perception during…
- Trial name
- NCT07571278
- Testing
- Vibraject, Dental vibe, Conventional syringe
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
First Trimester Abortion, Surgical Abortion
The Effect of Music Therapy Under Ultrasound Guided Manual Vacuum Aspiration
Manual vacuum aspiration (MVA) is one of the surgical treatment options for managing early pregnancy loss. When compared to traditional surgical method; MVA is safer, more cost-effective, due to its shorter hospitalisation period…
- Conditions
- First Trimester Abortion, Surgical Abortion, Music Intervention, Local Anesthesia
- Trial name
- NCT04708808
- Testing
- music therapy
- Where
- Hong Kong
- Volunteers
- 176 people
- Sponsor
- Chinese University of Hong Kong
Sacral Erector Spinae Plane Block, Pediatric Regional Anesthesia
Sacral Erector Spinae Plane Block Versus Penile Block For Analgesia In Pediatric Circumcision
Circumcision is one of the most frequently performed surgical procedures in childhood and is associated with significant postoperative pain.
- Conditions
- Sacral Erector Spinae Plane Block, Pediatric Regional Anesthesia, Regional Anaesthesia
- Trial name
- NCT07321717
- Testing
- Sacral Erector Spinae Plane Block, Penile Nerve Block (PNB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Caesarean Section, Spinal Anesthesia
Evaluating the Effectiveness of Ondansetron Versus Dexamethasone Versus Placebo for the Control of Intraoperative Nausea and Vomiting in Patients Undergoing Lower-segment Caesarean Section Under Spinal Anesthesia
The goal of this randomized controlled trial is to evaluate the effectiveness of Ondansetron, Dexamethasone, and Placebo for intraoperative nausea and vomiting in patients undergoing caesarian section under spinal anesthesia.
- Trial name
- ODP (NCT05583214)
- Testing
- Ondansetron 8mg, Dexamethasone 8mg, Normal saline
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Muhammad Mubariz
Anesthesia, Surgery--Complications
PACU for Postoperative Care After Major Thoracic and Abdominal Surgery
The aim of this study is to demonstrate the efficacy and safety of a specialised post-anaesthetic care unit (PACU) to a conventional intensive care unit (ICU) in adult patients after major thoracic and abdominal surgery.
- Trial name
- NCT05046925
- Testing
- postoperatively transferral to PACU, postoperatively transferral to ICU
- Where
- China
- Volunteers
- 18,000 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Elective Circumcision Surgery
A Comparison of the Efficacy of Sacral Erector Spinae Plane Block and Penile Block in Circumcision Surgery
Effective perioperative analgesia is crucial for reducing hospital stay in pediatric surgical patients. Opioid-based analgesia, although effective, may lead to respiratory depression in the postoperative period.
- Trial name
- SACRAL ESP (NCT07097844)
- Testing
- 0.8 mL/kg of 0.25% bupivacaine
- Volunteers
- 62 people
- Sponsor
- Siirt Training and Research Hospital
Pediatric, Anesthesia
Efficacy of Ultrasound-guided Internal Jugular Vein Versus Supraclavicular Subclavian Vein Cannulation in Neonates and Infants Less Than 5 kg.
The aim of this study is to compare the effectiveness and safety of ultrasound- guided IJV and supraclavicular SCV cannulation in infants weighing less than 5 kg.
- Conditions
- Pediatric, Anesthesia, Central Venous Catheter, Ultrasound
- Trial name
- NCT05956028
- Testing
- Ultrasound guided SCV cannulation, Ultrasound guided IJV cannulation
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Kasr El Aini Hospital
Hypotension
Efficacy of Dexamethasone in Attenuation of Postinduction Hypotension in Geriatric Patients Undergoing General Anesthesia
Geriatric patients who undergo general anesthesia experience post induction hypotension which is treated with intravenous fluids and ephedrine.
- Trial name
- NCT04908592
- Testing
- Dexamethasone
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Local Anesthesia
Efficacy and Safety of Lambdalina (Lidocaine Cream) Versus Placebo as an Anesthetic for Laser Hair Removal
Double-blind, randomized, placebo-controlled trial to assess the efficacy of Lambdalina (lidocaine cream) in reducing pain associated with laser hair removal in women.
- Trial name
- NCT01360749
- Testing
- Lambdalina® (Lidocaine 4% cream)
- Where
- 2 sites in Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- ISDIN
Airway Complication of Anaesthesia
The Clinical Efficacy of Recently Developed Supraglottic Airway Device, I-gel™, in Neonates and Infants: Comparison With Classic-laryngeal Mask Airway (c-LMA)
Although the safety and efficacy of the Classic-laryngeal mask airway (c-LMA) in children has been shown in several large observational studies, findings suggest that the smaller-sized c-LMAs, in particular sizes 1 and 1½, are…
- Trial name
- NCT01437137
- Testing
- classic-laryngeal mask airway (c-LMA), i-gel™
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Yonsei University
Urolithiasis
Comparison of General Anaesthesia and Sedation on the Stone Fragmentation in Lithotripsy
The aim of the study is to compare the impact intravenous sedation versus general anesthesia on the efficacy of stone fragmentation in extracorporeal shock wave lithotripsy treatment.
- Trial name
- NCT01361516
- Testing
- Anaesthesia and Lithotripsy
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Hadassah Medical Organization
Surgery, Anesthesia; Functional
Effectiveness of Continous Adjuvant Lidocaine on General Anaesthesia on Tumor Craniotomy Surgery
This study aims to investigate the effect of adjuvant continuous lidocaine in General Anesthesia on Depth of Anesthesia (qCON), Pain Response (qNOX), and Blood Sugar Levels in Elective Primary Tumor Craniotomy Surgery
- Conditions
- Surgery, Anesthesia; Functional, Haemodynamic Instability
- Trial name
- NCT06249113
- Testing
- NaCl 0.9%, Adjuvant lidocaine continous
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Gallbladder Stones, Gallbladder Polyps
A Study on the Efficacy and Safety of Anrikefon for Postoperative Pain Relief Following Laparoscopic Cholecystectomy
This study is a multicenter, randomized, 1:1 parallel-group controlled clinical trial designed to evaluate the efficacy and safety of Anrikefon for postoperative analgesia in patients undergoing elective laparoscopic…
- Trial name
- NCT07741188
- Testing
- Anrikefon, Dezocine
- Where
- 2 sites in China
- Volunteers
- 144 people
- Sponsor
- Affiliated Hospital of Guangdong Medical University
Regional Anesthesia Techniques in Shoulder Surgery
Effectiveness of Field Block Compared With Interscalene Block in Shoulder Surgery
This study will compare two different types of anesthesia used for shoulder surgery. The first method, called an interscalene block, is commonly performed by anesthesiologists and is effective for pain control but may cause side…
- Trial name
- BLOCK-SHOULDER (NCT07173894)
- Testing
- Shoulder Field Block by Orthopedic Surgeon, Interscalene brachial plexus block and superficial cervical plexus block
- Where
- Israel
- Volunteers
- 64 people
- Sponsor
- Rabin Medical Center
Anesthesia
Efficacy and Safety Profile of Remimazolam-alfentanil Combination for ERCP Sedation
Moderate to deep levels of sedation and analgesia are required for ERCP. Propofol-based sedation is simple, easy to use, and effective, but is not without cardiovascular and respiratory adverse effects.
- Trial name
- NCT04658173
- Testing
- remimazolam-alfentanil combination, propofol-alfentanil combination
- Where
- 2 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Tianjin Nankai Hospital
Balanced Anesthesia, Adjuvants,Anesthesia
The Study of Different Sedative Medications in Monitored Anesthesia Care During Eye Surgery With Local Anesthesia
Due to the delicacy and long duration of the procedure, ophthalmic surgery put forward higher requirements to anesthesia management: 1.
- Trial name
- MAC (NCT04018703)
- Testing
- Dexmedetomidine, Midazolam
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Anesthesia, Surgical Procedures, Elective
A Safety and Efficacy Study of Dexmedetomidine in Patients Requiring Sedation During Monitored Anesthesia Care (MAC)
The objective of this study is to evaluate the safety and efficacy of dexmedetomidine as compared to placebo when used for the sedation of subjects requiring monitored anesthesia care (MAC).
- Trial name
- NCT00398827
- Testing
- Dexmedetomidine
- Where
- 27 sites in United States
- Volunteers
- 326 people
- Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
Dexmedetomidine
Dexmedetomidine in Obturator Nerve Block as an Analgesic in Transurethral Surgeries
in our study, we will investigate the impact of adding dexmedetomidine to bupivacaine for the potency of the obturator nerve block and prevention of the postoperative pain associated with transurethral surgery in comparison of…
- Trial name
- NCT06229054
- Testing
- Dexmedetomidine, Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
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