Clinical trials: Anesthesia Effectiveness
Colonoscopy
A Study Evaluating Tolerability, Efficacy, and Safety of HSK3486 Injectable Emulsion in Patients
A double-blind, randomized, active controlled, multi-center, parallel group study comparing HSK3486 with Propofol, in patients undergoing a colonoscopy.
- Trial name
- NCT03773042
- Testing
- HSK3486, Propofol
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
Thoracic Surgery, Anesthesia
Cerebral Oximetry-Guided Low FiO2 Strategies in Thoracic Surgery.
Brief Summary (Kısa Özet)The purpose of this study is to evaluate the safety and efficacy of a cerebral oximetry-guided low fraction of inspired oxygen (FiO_2) ventilation strategy compared to a standard high FiO_2 strategy in…
- Trial name
- NCT07659483
- Testing
- Standard High $FiO_2$ Strategy, Guided Low $FiO_2$ Strategy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dicle University
Analgesia After Laparoscopic Cholecystectomy
Opioid-Free Analgesia for Laparoscopic Cholecystectomy
laparoscopic cholecystectomy (LC) is often accompanied by moderate-to-severe postoperative pain. opioid-free anesthesia (OFA) consists of a variety of non-opioid narcotic drugs and techniques.
- Trial name
- NCT07750769
- Testing
- EOI with OFA, OFA
- Volunteers
- 70 people
- Sponsor
- Assiut University
Hemorrhoids
Local Anaesthetic Day-care Haemorrhoidectomy Challenges Traditional Concepts - a Randomised Controlled Trial
Background: Local anaesthetic day-care open haemorrhoidectomy (LH) is feasible, cheap and may be the cost-effective surgical approach to third degree haemorrhoids.
- Trial name
- NCT00503269
- Testing
- Hemorrhoidectomy
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- East Kent Hospitals University NHS Foundation Trust
Breast Cancer Female
USG PECS vs LIA for Breast Cancer Surgery
Breast cancer is the most common cancer for which women in the UK (United Kingdom) undergo surgery. A novel ultrasound guided regional anaesthetic technique called the 'Pecs 2' block has recently been described.
- Trial name
- NCT03555227
- Testing
- USG PECS2 with Drug A (active), Wound infiltration with Drug A (active)
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- National Health Service, United Kingdom
Colonoscopy, Ketamine
Comparison of Efficacy of Anesthesia Administered by Endoscopist or Anesthesiologist on Colonoscopy
In sedation applications performed by an endoscopist or anesthetist during colonoscopy, it was investigated whether there were differences in pain levels evaluated by VAS (Visuel analog scale), patient satisfaction, duration of…
- Conditions
- Colonoscopy, Ketamine, Fentanyl
- Trial name
- NCT03607110
- Testing
- Ketamine, fentanyl, patient control analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Selda KAYAALTI
Postoperative Nausea and Vomiting
Aprepitant for PONV Prophylaxis in Outpatient Plastic Surgery
Hypothesis: Aprepitant plus ondansetron is more effective than ondansetron plus placebo for prevention of postoperative emesis in patients at moderate-to-high risk for PONV for up to 48 hours after surgery.
- Trial name
- NCT00659945
- Testing
- Aprepitant plus Ondansetron
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Incidence Conversion to General Anesthesia, Interleukin-6, Total Tramadol Consumption and Pain Score After Surgery
Erector Spinae Plane Block and Spinal Anesthesia for Supine Percutaneous Nephrolithotomy
This study aimed to compare the Effectiveness of Erector Spinae plane block to Spinal as a surgical anesthesia and analgesia in Percutaneous Nephrolithotomy patient
- Trial name
- NCT04947072
- Testing
- Erector Spinae Plane Block, Spinal anesthesia
- Where
- Indonesia
- Volunteers
- 30 people
- Sponsor
- Universitas Indonesia
Total Laparoscopic Hysterectomy
Acupuncture for Blood Pressure Fluctuation During Total Laparoscopic Hysterectomy
The goal of this pilot clinical trial is to learn about efficacy of acupuncture about blood pressure fluctuation during total laparoscopic hysterectomy in patients with uterine fibroid.
- Trial name
- ASBP (NCT05720884)
- Testing
- acupuncture
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Ilsan Cha hospital
Post Operative Analgesia
Comparison of Efficacy of Bupivacaine Alone vs. Bupivacaine-Tramadol in Lower Limb Surgery
This randomized controlled trial aims to compare the effectiveness of bupivacaine alone versus bupivacaine combined with tramadol for postoperative analgesia in patients undergoing lower limb surgeries under spinal anesthesia.
- Trial name
- BUP-TRA-PAIN (NCT07827352)
- Testing
- Bupivacain only, bupivacain-tramadol
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Farooq Hospital / Akhtar Saeed Medical college Rawalpindi
Educational Problems
The Efficacy of Biplane Versus Single Plane Ultrasound in Facilitating Caudal Epidural Anesthesia in Pediatric Patients.
Ultrasound guidance plays a pivotal role in caudal epidural block in pediatric patients. In comparison to conventional single-plane ultrasound, biplane ultrasound offers the advantage of providing simultaneous transverse and…
- Trial name
- NCT06319989
- Testing
- Biplane Ultrasound, Single plane ultrasound
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Florida
Acute Pain, Post Operative Analgesia
Analgesic Efficacy of Combined PECS II and PIP Block Versus Thoracic Paravertebral Block Post-Mastectomy
Postoperative pain management is crucial for patients undergoing mastectomy for breast cancer. Regional analgesia techniques, such as the Thoracic Paravertebral Block (TPVB), are commonly used to reduce pain and opioid…
- Conditions
- Acute Pain, Post Operative Analgesia, Post Operative Pain, Acute, Breast Cancer
- Trial name
- PECS-TPVB (NCT07738770)
- Testing
- Combined PECS II and Superficial PIP Block, Thoracic paravertebral block (TPVB)
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Dharmais National Cancer Center Hospital
General Anesthetic
HSK3486 (Cipepofol) Injectable Emulsion for Induction of General Anesthesia in Pediatric Subjects Undergoing Elective Surgery
This multicenter, randomized, double-blinded, propofol-controlled Phase 3b study enrolls pediatric subjects aged 3-17 years undergoing elective surgery with endotracheal intubation.
- Trial name
- NCT07510945
- Testing
- HSK3486, propofol
- Volunteers
- 400 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Ablation Techniques, RFA, Ablation Treatment
Efficacy and Safety of RFA vs MWA for Treatment of Large Benign Thyroid Nodules, RCT
We conduct a multi-institutional randomized control trial of RFA and MWA for the primary treatment of large, benign nodules. Adult patients >/=18 years of age who have a solitary thyroid nodule ≥20ml in volume who presents to 1)…
- Conditions
- Ablation Techniques, RFA, Ablation Treatment, Benign Thyroid Nodules, Local Anaesthesia
- Trial name
- NCT07804862
- Testing
- Radiofrequency ablation alone, Microwave ablation
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Post Operative Sore Throat
Evaluation of the Efficacy of Preoperative Ketamine Nebulization on Postoperative Sore Throat Due to Tracheal Intubation for Adult Patients Under General Anesthesia, A Prospective Randomized Controlled Study
Sore throat includes specific symptoms such as dysphagia, dysphonia, hoarseness, continuous throat pain, and pharyngeal dryness.
- Trial name
- NCT05975346
- Testing
- Ketamine, saline nebulization
- Volunteers
- 80 people
- Sponsor
- Sohag University
Pain Management, Anaesthesia Complication
Efficacy of Variable Volume Truncal Blocks in Upper Limb Orthopedic Surgery
aim of this study is to compare the effect of selective truncal blocks, performed at different doses and volumes, on the onset times of motor and sensory blocks required for anesthesia in patients scheduled for hand, wrist…
- Trial name
- NCT06664203
- Testing
- Selective turuncus block with 25 ml bupivacain, Selective turuncus block with 15 ml bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
MIH, Molar-Incisor Hypomineralization
Effects of Silver Diamine Fluoride and Intraoral Cryotherapy on Local Anesthesia in MIH-Affected Molars
Molar-incisor hypomineralization (MIH) is a developmental enamel defect of unclear etiology that affects permanent first molars and often permanent incisors, leading to increased porosity, hypersensitivity, and poor prognosis.
- Conditions
- MIH, Molar-Incisor Hypomineralization, Caries Assessment
- Trial name
- NCT07326241
- Testing
- Standard Local Anesthesia, Intraoral Cryotherapy, Silver Diamine Fluoride (SDF)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Knee Osteoarthritis, Knee Arthritis
Intra-Operative Adductor Canal Blocks
Adductor canal blocks (ACB) have been recommended in total knee arthroplasty (TKA) to provide better control of post-operative pain, facilitate early ambulation, and reduce length of stay in the hospital.
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Anesthesia
- Trial name
- NCT05601427
- Testing
- aACB, sACB
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Ottawa Hospital Research Institute
Analgesia, Pain
Effectiveness of Ultrasound (US) Guided Supraclavicular Block
This research study is being done in order to find out if there is any difference in the effectiveness of ultrasound guided supraclavicular brachial plexus nerve block that can be achieved with 3 different amounts of ropivacaine…
- Trial name
- NCT00923494
- Testing
- 20 ml of ropivacaine 0.5%, 30 ml of ropivacaine 0.5%, 40 ml of ropivacaine 0.5%
- Where
- United States
- Sponsor
- Baylor College of Medicine
Cardiac Implantable Electronic Device, Nerve Block
PECs for Implantable Cardiac Electronic Device Insertion
The aim of this study is to evaluate the feasibility of the Pectoralis Nerve (PECS) block for CIED insertion.
- Conditions
- Cardiac Implantable Electronic Device, Nerve Block, Anesthesia, Analgesia
- Trial name
- NCT05528627
- Testing
- Pectoral Nerve (PECs) block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Antalya Training and Research Hospital
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