Clinical trials: Anesthesia Effectiveness
Hypothermia; Anesthesia, Hypothermia, Newborn
Perioperative Warming Measures in Cesarean Delivery
The purpose of this study is to evaluate the best method for keeping patients warm during cesarean deliveries and the effect of temperature change on the patient and baby
- Conditions
- Hypothermia; Anesthesia, Hypothermia, Newborn, Hypothermia, Sequela
- Trial name
- NCT05015582
- Testing
- Pre op upper body forced air warming (32˚C), Pre op lower body forced air warming (32˚C), Pre op fluids (45˚C)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pediatric ALL
Exploring the Minimum Effective Concentration and Volume of Ropivacaine for Sacral Plexus Anesthesia
The goal of this clinical trial is to explore the minimum effective concentration and volume of ropivacaine for sacral plexus anesthesia.
- Trial name
- NCT06711679
- Testing
- Low-dose ropivacaine, Medium-dose of ropivacaine, High-dose ropivacaine
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Yilin Zhao
Local Anesthesia
Safety and Efficacy Study of an Iontophoretic Patch Containing Lidocaine and Epinephrine for Venipuncture in Healthy Adult Volunteers
The purpose of this study is to evaluate the effectiveness of administering Lidocaine and Epinephrine using an iontophoretic device treatment to provide local anesthesia to healthy adult volunteer subjects undergoing venipuncture.
- Trial name
- NCT00889642
- Testing
- Iontophoretic Drug Delivery System with Lidocaine/Epinephrine, Iontophoretic Drug Delivery System with Epinephrine
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dharma Therapeutics Inc.
Postoperative Pain
Comparison of Pain Relief Duration With Dexmedetomidine Versus Fentanyl Added to Spinal Anesthesia in Patients Undergoing Lower Limb Orthopedic Surgery
The goal of this randomized clinical trial is to compare how long effective pain relief lasts when dexmedetomidine or fentanyl is added to hyperbaric bupivacaine during spinal anesthesia for lower limb orthopedic surgery.
- Trial name
- NCT07770542
- Testing
- Dexmedetomidine & Bupivacaine., fentanyl and bupivacaine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Allama Iqbal Teaching Hospital
Anesthesia
Study of Efficacy, Pharmacokinetics and Safety of Continuous Intravenous Infusion of Org 9426 (Study P05977)
The purpose of this study is to compare the infusion rate of Org 9426 following intubating dose of Org 9426 0.6 mg/kg or 0.9 mg/kg in adult surgical patients.
- Trial name
- NCT00988520
- Testing
- Rocuronium bromide, Sevoflurane, Propofol
- Volunteers
- 38 people
- Sponsor
- Merck Sharp & Dohme LLC
Spinal Anesthesia
Minimum Effective Dose of Ropivacaine for Spinal Anesthesia for Cesarean Delivery
Ropivacaine is one of commonly used anesthetics for spinal anesthesia. Usually L2-3 or L3-4 intervertebral space is chosen for spinal anesthesia.
- Trial name
- NCT02565303
- Testing
- Intervertebral space, Ropivacaine
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai 6th People's Hospital
Anesthesia, Respiratory Diseases
Efficacy of Different Anesthesia Methods in Transbronchial Biopsy
This study investigates the efficacy of different anesthesia methods (general anesthesia with laryngeal mask airway and local nebulized anesthesia) for transbronchial biopsy using an electronic bronchoscope.
- Conditions
- Anesthesia, Respiratory Diseases, Biopsy
- Trial name
- EDAMTBB (NCT06454513)
- Testing
- general anesthesia
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Sichuan Provincial People's Hospital
Postoperative Pain, Postoperative Vomiting
Efficacy of Dexmedetomidine for Postoperative Analgesia in Infantile Cataract Surgery
The purpose of the present study was to evaluate the efficacy and safety of subtenon block (SB)anesthesia with dexmedetomidine in combination with bupivacaine versus intravenous dexmedetomidine for postoperative analgesia and…
- Trial name
- NCT02495220
- Testing
- SB dexmedetomidine bupivacaine block, intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Gallbladder Stones, Gallbladder Polyps
A Study on the Efficacy and Safety of Anrikefon for Postoperative Pain Relief Following Laparoscopic Cholecystectomy
This study is a multicenter, randomized, 1:1 parallel-group controlled clinical trial designed to evaluate the efficacy and safety of Anrikefon for postoperative analgesia in patients undergoing elective laparoscopic…
- Trial name
- NCT07741188
- Testing
- Anrikefon, Dezocine
- Where
- 2 sites in China
- Volunteers
- 144 people
- Sponsor
- Affiliated Hospital of Guangdong Medical University
Surgery, Anesthesia
Comparing the Effectiveness of Modified ERAS Protocols vs. Standard Management in Pediatric Gastrointestinal Surgery
Perioperative management of pediatric patients with gastrointestinal diseases involves a fairly length process and which can lead to rapid deterioration even death.
- Trial name
- NCT06981572
- Testing
- Modified Enhanced Recovery After Surgery Protocol
- Where
- Indonesia
- Volunteers
- 82 people
- Sponsor
- Universitas Indonesia
Post Operative Analgesia, Regional Anaesthesia
Comparison Between Paravertebral and Erector Spinal Block Efficacy in Robotic Thoracic Surgeries
The overall goal of this work is to find the preferred continues catheter- based thoracic block for patients who undergoing major ROBOTIC assisted thoracic surgery (Lobectomy, multiple segmental resection and thoracotomy).
- Conditions
- Post Operative Analgesia, Regional Anaesthesia, Pain After Surgery, Opioid Consumption
- Trial name
- TPVB vs ESP (NCT07782073)
- Testing
- Paravertebral Nerve Block, ESP block group
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Soroka University Medical Center
Orotracheal Intubation in Infants Requiring General Anaesthesia for Surgery
Comparing the Efficacy of King Vision in Infants
The primary objective of this study is to find out whether the intubation success rates of Kingvision video laryngoscope is better than that of the conventional laryngoscopes in children < 1 year of age?
- Trial name
- NCT03378154
- Testing
- Orotracheal intubation in infants with Macintosh, Orotracheal intubation in infants with King vision
- Where
- India
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Jawaharlal Institute of Postgraduate Medical Education & Research
Proximal Humeral Fracture
Paravertebral Block for Proximal Humeral Fracture Surgery
This study evaluates the effects of T2 paravertebral block block improving interscalene brachial plexus block and superficial cervical plexus block on the relief of pain intensity during elderly proximal humerus fracture fixation…
- Trial name
- NCT03919422
- Testing
- T2 paravertebral block, interscalene brachial plexus block and superficial cervical plexus block
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai 6th People's Hospital
Post-Dural Puncture Headache
Is Theophylline More Effective Than Sumatriptan in the Treatment of Post-dural Puncture Headache
Objectives: To compare the safety and efficacy of oral theophylline versus oral sumatriptan in the treatment of post-dural puncture headache (PDPH).
- Trial name
- NCT04257851
- Testing
- Theophylline Anhydrous Oral Tablet, Sumatriptan Succinate Oral Tablet
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Damanhour Teaching Hospital
Anesthesia, General
Efficacy and Safety of Ciprofol Compared to Propofol for Nonintubated General Anesthesia in Patients Undergoing TAVR
The purpose of this study is to explore the efficacy and safety of ciprofol compared to propofol for non-intubated general anesthesia in patients undergoing transcatheter aortic valve replacement (TAVR).
- Trial name
- NCT05035069
- Testing
- Ciprofol, Propofol
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Postmastectomy Pain
SPSIP Block in Breast Surgeries for Postoperative Analgesia
The aim of this clinical study is to demonstrate that pain following breast surgeries can be reduced through the application of serratus posterior superior intercostal plane block (SPSIPB).
- Trial name
- SPSIPB (NCT06100419)
- Testing
- serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Airway Management
Compare the Efficacy of Different Laryngeal Mask Size Selection Methods in General Anesthesia in Children
The laryngeal mask is widely used in general anesthesia in children. Selection of an appropriately sized laryngeal mask airway (LMA) is critical to ensure safe and effective use of the device.
- Trial name
- NCT03845998
- Testing
- use the three-finger method, use the weight-related method
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Pain, Inguinal Hernia
Comparison of Two Different Pain Management Techniques in Pediatric Patients Undergoing a Hernia Repair
The purpose of this research study is to find the best way to decrease pain in children right after surgery whom have had their hernia fixed.
- Trial name
- NCT01740193
- Testing
- TAP Block, Ilioinguinal/iliohypogastric blockade
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Surgery, Anesthesia, Local
Efficacy of Ultrasound-guided Axillary Nerve Block Versus Ultrasound-guided Peripheral Forearm Block in Patients Undergoing Hand Surgery
By means of an observer-blinded, mono-center, prospective, randomized controlled superiority trial, the total anesthesia-related time (sum of performance and onset times) of an ultrasound-guided distal peripheral nerve block and…
- Trial name
- NCT04678765
- Testing
- Ultrasound-guided distal peripheral nerve block, Ultrasound-guided quadruple-injection axillary nerve block
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Jessa Hospital
Anesthesia
Ultrasound-Guided Intermediate Versus Deep Cervical Plexus Block for Carotid Endarterectomy
Cervical plexus blocks are regional methods used in carotid endarterectomy. Cervical plexus blocks consist of three blocks: superficial, intermediate and deep. These three blocks can be used alone or combined.
- Trial name
- NCT05353218
- Testing
- Intermediate cervical plexus block, Deep cervical plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University
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