Clinical trials: Anesthesia Effectiveness
Anesthesia, Local
Anesthetic Efficacy of PECS II Block and Parasternal Block
The study evaluate the anesthetic efficacy of Pecs II block II and parasternal block during quadrantectomy with or without axillary dissection, in breast cancer surgery
- Trial name
- NCT03016117
- Testing
- Pecs II block and parasternal block
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- San Salvatore Hospital of L'Aquila
Stroke
SEdation Versus General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke
Objectives: This study aims to estimate overall treatment benefit (improvement in disability) among acute ischemic stroke patients that are randomized to General Anesthesia (GA) compared with Sedation (CS) during endovascular…
- Trial name
- SEGA (NCT03263117)
- Testing
- Sedation, General Anesthesia (GA), Intra-arterial Thrombectomy
- Where
- 11 sites in United States
- Volunteers
- 260 people
- Sponsor
- The University of Texas Health Science Center, Houston
Ivabradine, Propranolol
Efficacy of Ivabradine Versus Propranolol Premedication During Hypotensive Anesthesia in Endoscopic Sinus Surgery
50 Patients, aged from 18 to 39 years, ASA physical status I and II, undergoing endoscopic sinus surgery will be enrolled in the study.The patients will be randomly allocated by simple randomization using a computer programme…
- Conditions
- Ivabradine, Propranolol, Hypotensive Anesthesia
- Trial name
- NCT04208594
- Testing
- Ivabradine, Propranolol
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Insomnia
Study on the Efficacy and Safety of Anesthesia-Induced Sleep Therapy for Refractory Insomnia
The incidence of refractory insomnia is rising annually, with traditional therapies offering limited efficacy. Anesthesia-Induced Sleep (AIS), involving anesthetic infusion like dexmedetomidine, is emerging.
- Trial name
- NCT07255027
- Testing
- Dexmedetomidine and conventional oral drug, Conventional oral drug therapy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Hypersalivation, Prevention of Drooling
Efficacy of Intravenous Glyco-P® in Patients Undergoing Procedure That Require Anesthesia Service
This observational study was designed to prove clinical efficacy of the well known "glycopyrrolate" which is considered an orphan drug in Thailand.
- Conditions
- Hypersalivation, Prevention of Drooling, Bradycardia, Reversal of Muscle Relaxants
- Trial name
- NCT02102542
- Where
- Thailand
- Volunteers
- 65 people
- Sponsor
- Mahidol University
Postoperative Pain, Surgery
Local Anesthesia Versus Saline Serum in Surgical Incision of Colorectal or Hepatic Surgery
The purpose of this study is to determine whether a continuous infusion of local anesthesia with a catheter in the surgical wound reduces patient consumption of opiates by 30% in the 48-hour postoperative period following surgery…
- Conditions
- Postoperative Pain, Surgery, Postoperative Complications
- Trial name
- CATROP-2007 (NCT01075646)
- Testing
- ropivacaine, saline solution
- Where
- Spain
- Volunteers
- 225 people
- Sponsor
- Hospital Universitari de Bellvitge
Postoperative Cognitive Dysfunction, Anesthesia
Neurological Effects of Goal-directed Fluid Therapy in Beach Chair Position Shoulder Surgery
Patients receiving beach chair position shoulder surgery are vulnerable to perioperative cerebral desaturation, which is reported to be a risk factor for postoperative cognitive dysfunction.
- Trial name
- NCT03963063
- Testing
- Goal-directed fluid therapy, Non goal-directed fluid therapy
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Regional Anesthesia
Comparison of Postoperative Analgesic Efficacy of Transversalis Fascia Plan Block and Erector Spina Plan Block
The subject of the study is to compare the analgesic efficacy of transversalis fascia plan block and erector spina plane block applied with ultrasonography in patients who have undergone inguinal hernia operation.
- Trial name
- NCT05344105
- Testing
- Low frequency convex probe (ESAOTE Fixed Color Doppler Ultrasonography Device, Italy)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Samsun Education and Research Hospital
Postoperative Pain
Regional Anesthesia in THR - Comparing the Analgesic Efficacy of Fascia Iliaca Block and Erector Spinae Plane Block
THR (Total Hip Replacement) can be very painful and regional anesthesia is very effective in reducing postoperative pain. Fascia Iliaca Block (FIB) and Erector Spinae Plane Block (ESPB) are indirect approaches to the lumbar…
- Trial name
- PTA-ALR (NCT04574154)
- Testing
- FIB, ESPB, spinal anesthesia
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Papa Giovanni XXIII Hospital
Hypnosis, Local Anaesthesia
Evaluation of the Effectiveness of Hypnosis Support on Patient Perception of Outpatient Surgery Under Local Anaesthesia
Many clinical trials assessing the effectiveness of hypnosis have been conducted in recent years, some of which show that hypnosis reduces pain perception better than drug treatments administered to control groups, and that it is…
- Conditions
- Hypnosis, Local Anaesthesia, Outpatient Surgery, FACE
- Trial name
- HYPNOFACE (NCT03926403)
- Testing
- State-Trait Anxiety Inventory ("Spielberger Self-Assessment Questionnaire"), hypnosis techniques, local anaesthesia
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Anesthesia, Conduction, Ropivacaine
Minimal Effective Concentration (EC90) of Ropivacaine
Prospective up and down sequential evaluation of the minimal effective concentration of perineural ropivacaine for 90% success in axillary brachial plexus block with the injection of intravenous dexamethasone or saline placebo…
- Conditions
- Anesthesia, Conduction, Ropivacaine, Dexamethasone, Axillary Brachial Plexus Block
- Trial name
- AxiRopiDexa (NCT03688269)
- Testing
- Intravenous dexamethasone, Intravenous saline, Perineural ropivacaine
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Pain, Postoperative
Efficacy of Dexmedetomidine as an Adjuvant to Quadratus Lumborum Block
This prospective double blinded study will be conducted over 60 pediatric patients ASA (American Association of Anesthesiologists) I and II between the age of 1-7 years old, who will be scheduled for unilateral groin surgery.
- Trial name
- NCT05979376
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Inferior Alveolar Nerve Block
Pain and Anxiety Control During Traditional Mandibular Anesthesia in Children Using Distracting Tools
The aim of this study is to evaluate the effectiveness of two different audiovisual distraction techniques (Audio Video eyeglasses "VR BOX"/ Tablet) in the management of anxious pediatric patients during inferior alveolar nerve…
- Trial name
- NCT03428282
- Testing
- VR Box, Tablet Device, Anesthesia
- Where
- Syria
- Volunteers
- 102 people
- Sponsor
- Damascus University
Breast Cancer
Erector Spinae Block in Segmental Mastectomy.
Erector spinae plane block (ESPB) is a recently described block. Although there is still no consensus of its mechanism, the published case series seems to promise a new regional anesthesia technique for both chronic and acute…
- Trial name
- NCT03509090
- Testing
- erector spinae block, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Maltepe University
Sphenopalatine Ganglion Block, General Anesthesia
Sphenopalatine Ganglion Block as Adjuvant to General Anesthesia Regarding the Quality of Surgical Field in Trans-Sphenoidal Endoscopic Hypophysectomy
This study aims to evaluate the efficacy of ultrasound guided sphenopalatine ganglion block (SPGB) through the suprazygomatic approach in optimizing the quality of surgical field as well as its effect on postoperative pain relief…
- Conditions
- Sphenopalatine Ganglion Block, General Anesthesia, Quality of Surgical Field, Trans-Sphenoidal Endoscopic Hypophysectomy
- Trial name
- NCT07569952
- Testing
- Sphenopalatine ganglion block using bupivacaine + dexamethasone, General anesthesia
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Local Anesthesia, Intradermal Injections
A Study to Assess the Safety and Efficacy of a Microneedle Device for Local Anesthesia
The purpose of this study is to determine whether the MicronJet microneedle device is effective for inducing rapid and painless local anesthesia prior to insertions of intravenous catheters.
- Trial name
- NCT00539084
- Testing
- MicronJet
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NanoPass Technologies Ltd
Pulpitis - Irreversible
Effect of Menstrual Phase on the Anesthetic Efficacy
The goal of this observational prospective clinical study is to learn whether the menstrual phase influences the anesthetic efficacy of inferior alveolar nerve block (IANB) in female patients aged 20-40 years with symptomatic…
- Trial name
- NCT07306533
- Testing
- Inferior Alveolar Nerve Block
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Jamia Millia Islamia
Smoking ( Cigarette)
Effectiveness of Brief Smoking Cessation Counselling in Pre-Anaesthesia Assessment Clinic
The goal of this clinical trial is to evaluate whether a brief, nurse-delivered smoking cessation intervention can increase pre-operative smoking abstinence and improve perioperative outcomes among adult elective surgical…
- Trial name
- NCT07505147
- Testing
- Nurse-led AWARD brief smoking cessation counselling with active referral and tailored perioperative booklet in the pre-anaesthetic assessment clinic, Usual pre-anaesthetic care without structured smoking cessation
- Where
- Hong Kong
- Volunteers
- 125 people
- Sponsor
- Pok Oi Hospital
Hip Fracture
Comparison of Three Analgesic Strategies for Hip Fracture Surgery
Hip fracture surgery is associated with significant postoperative pain and increased opioid requirements. Regional anesthesia techniques may improve analgesia and reduce opioid consumption.
- Trial name
- HIP-3B (NCT07676734)
- Testing
- Quadro-Iliac Plane Block, Suprainguinal Fascia Iliaca Block, Standard Multimodal Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Pain
The Anesthetic Efficacy of 3% Mepivacaine Plus 2% Lidocaine With 1:100,000 Epinephrine for Lower Jaw Dental Injections
The inferior alveolar nerve block (shot) is the most frequently used injection technique for achieving local anesthesia (numbness) for the teeth in the lower jaw.
- Trial name
- NCT01574807
- Testing
- mepivacaine + lidocaine followed by lidocaine +lidocaine, lidocaine + lidocaine followed by mepivacaine + lidocaine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ohio State University
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