Clinical trials: Anesthesia Effectiveness
Postoperative Pain, Postoperative Complications
Comparison of the Efficacy of Peripheral Nerve Blocks in Major Open Gynaecological Cancer Surgery
The aim of this prospective randomized study was to compare the effectiveness of subcostal transversus abdominis plane block or rectus sheath block applied in addition to posterior transversus abdominis plane block for…
- Conditions
- Postoperative Pain, Postoperative Complications, Analgesia, Regional Anesthesia Morbidity
- Trial name
- NCT06342076
- Testing
- Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block, Patients undergoing rectus sheat block and posterior transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Anesthesia, General
A Bridging Trial Comparing Sugammadex (Org 25969) at Reappearance of T2 in Japanese and Caucasian Participants. Part B: Caucasian Participants (P05971)
The objective of the trial was to establish the dose-response relation of sugammadex (Org 25969) given as a reversal agent of rocuronium or vecuronium at reappearance of T2 (the amplitude of the first response of second twitch to…
- Trial name
- NCT00552617
- Testing
- Sugammadex, Rocuronium, Vecuronium
- Volunteers
- 100 people
- Sponsor
- Merck Sharp & Dohme LLC
Anesthesia
The Median Effective Dose of Remimazolam for Duodenoscopy Insertion During ERCP With Alfentanil 10µg/kg
Remimazolam has shown promising results for sedation in colonoscopy . Alfentanil is widely used in the analgesia of ERCP . The purpose of the study was to determine the median effective dose of remimazolam for duodenoscopy…
- Trial name
- NCT04969068
- Testing
- Remimazolam
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tianjin Nankai Hospital
Dental Anxiety, Pain Management
Effectiveness of Virtual Reality Technique on Children
Studying the effect of using virtual reality technique in managing pain, anxiety, and vital signs among pediatric dental patients.
- Conditions
- Dental Anxiety, Pain Management, Pediatric Dentistry
- Trial name
- NCT07722221
- Testing
- Conventional, Virtual reality
- Where
- Syria
- Volunteers
- 64 people
- Sponsor
- Latakia University
Hypertension
The Effects of Scalp Block With Bupivacaine Versus Levobupivacaine
Ninety American Society of Anesthesiologists (ASA) Physical Status classification system I-II patients were recruited for a randomised, placebo-controlled, double-blind study and were randomly divided into three groups to receive…
- Trial name
- NCT02497040
- Testing
- Levobupivacaine, Bupivacaine
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Uludag University
Perioperative Bleeding, Opioid Consumption
Ultrasound-Guided Erector Spinae Plane Block in Major Spinal Surgery
This study aims to evaluate the effects of ultrasound-guided bilateral erector spinae plane block on intraoperative pain control and bleeding in patients undergoing major spinal surgery.
- Conditions
- Perioperative Bleeding, Opioid Consumption, Erector Spinae Plane Block, Spinal Stabilization
- Trial name
- NCT07101198
- Testing
- Ultrasound-guided erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Postoperative Pain Management, Knee Surgery
Comparison of ACB With ACB and BiFeS Combination in Knee Arthroplasty Surgeries
The aim is to compare the postoperative analgesic effects of Adductor Canal and Biceps Femoris Short Head Blocks with Adductor Canal Block in patients undergoing Knee Arthroplasty surgery
- Conditions
- Postoperative Pain Management, Knee Surgery, Knee Arthroplasty, Total
- Trial name
- NCT07233785
- Testing
- Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + Biceps Femoris Short Head Block (BiFeS)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cumhuriyet University
Breast Neoplasms, Anesthesia
Single Versus Multiple Injection Ultrasound Guided Paravertebral Blocks
Paravertebral block (PVB) has been shown to provide excellent analgesia for major breast surgeries resulting in reduced narcotic consumption, reduced nausea, improved quality of recovery, reduced chronic pain and possibly reduced…
- Trial name
- NCT02852421
- Testing
- Single injection paravertebral block, Multiple injection paravertebral blocks
- Where
- 2 sites in Canada
- Volunteers
- 70 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Thoracic Surgery, Analgesics, Opioid
Opioid Free Anesthesia in Thoracic Surgery
Proper assessment of pain and adequate analgesia in thoracic surgery is a challenging issue for medical practitioners. Basic aspects of thoracic anaesthesia are general anesthesia, intubation with double lumen tube and separation…
- Conditions
- Thoracic Surgery, Analgesics, Opioid, Anesthesia, Conduction
- Trial name
- NCT04355468
- Testing
- Opioid Anesthesia, Opioid Free Anaesthesia
- Where
- Poland
- Volunteers
- 66 people
- Sponsor
- Medical University of Silesia
Anesthesia, Regional
Adductor Canal Block (ACB) Before and After Primary Total Knee Arthroplasty (TKA)
Total knee arthroplasty (TKA) is associated with severe postoperative pain. Multimodal analgesia, including peripheral nerve block, is recommended for post-operative pain relief 1.
- Trial name
- NCT02908711
- Testing
- 0.5% ropivacaine
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Rabin Medical Center
Adjuvants, Anesthesia, Brachial Plexus Anesthesia
Variation in the Effect of Dexamethasone Associated With Axillary Plexus on the Occurrence of Rebound Pain
The study will evaluate pain and recovery after a single injection axillary plexus block combined with an intravenous dose of 0.1 mg/kg dexamethasone in ambulatory patients undergoing upper extremity bone surgery.
- Trial name
- VEDR (NCT05763433)
- Testing
- upper extremity bone surgery
- Volunteers
- 100 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Shivering
Comparative Study Between the Efficacy of Intravenous Hydrocortisone and Intravenous Dexmedetomidine for Prevention of Postoperative Shivering After General Anaesthesia for Abdominal Surgeries
The aim and purpose of this study is to compare the efficacy of intravenous hydrocortisone and intravenous dexmedetomidine for prevention and treatment of postoperative shivering after general anesthesia for abdominal surgeries.
- Trial name
- NCT07154849
- Testing
- Hydrocortisone, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Facial Plane Blocks
Comparison of the Efficacy of One Level and Tow Level of Bilateral Thoracic Erector Spinae Plane Block Combined With General Anesthesia in Laparoscopic Bariatric Surgery for Obese Patients: Randomized Controlled Trial
comparison of the feasibility and efficacy of the one-level and two-level thoracic ESP block and their effect on intraoperative and postoperative analgesia in bariatric surgeries.
- Trial name
- NCT06811493
- Testing
- bilateral thoracic erector spinae plane block combined with general anesthesia in laparoscopic bariatric surgery in obese patients
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Anterior Cervical Discectomy, Serratus Posterior Superior Intercostal Plane Block
Postoperative Analgesic Efficacy of SPSIPB in Anterior Cervical Discectomy
Anterior cervical discectomy is an operation performed for complaints of pain, numbness or loss of strength due to cervical disc disease.
- Conditions
- Anterior Cervical Discectomy, Serratus Posterior Superior Intercostal Plane Block, Postoperative Pain Management, Postoperative Pain
- Trial name
- NCT07238621
- Testing
- The group treated with intravenous analgesics, Serratus posterior superior intercostal plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cumhuriyet University
Anesthesia, Local
Effective Use of Pecs and Transversus Thoracics Plane Blocks for Subcutaneous Cardiac Pacemaker Insertion: A Case Series
Participants that undergo permanent cardiac pacemaker implantation can often present with challenging anesthetic management plans for the anesthesia provider.
- Trial name
- NCT03899701
- Testing
- PEC I and PEC II blocks
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Anesthesia; Functional, Anesthesia
The Efficacy of 20 mg Parecoxib as an Adjunct to 0.75% Ropivacaine in Supraclavicular Brachial Plexus Block for Upper Limb Surgery
This clinical trial aims to investigate the efficacy of 20 mg Parecoxib when it is given as an addition to 20 ml 0.75% ropivacaine in patients receiving ultrasound-guided supraclavicular brachial plexus block prior to the upper…
- Trial name
- RCT (NCT03480165)
- Testing
- Parecoxib 20 MG/ML, Ropivacaine
- Where
- Malaysia
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Single Lung Ventilation, Thoracic Surgery
Double-lumen Tubes (DLT) - Health Economic Study
The aim of this study is to make a health economic evaluation comparing novice physicians use of VivaSight double-lumen tube and a conventional double-lumen tube for single-lung ventilation during thoracic surgery at a teaching…
- Conditions
- Single Lung Ventilation, Thoracic Surgery, Anesthesia, Cost-effectiveness
- Trial name
- NCT03817879
- Testing
- VivaSight double-lumen tube for single-lung ventilation, Conventional double-lument tube for single-lung ventilation
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Ambu A/S
Opioid Use, Spine Fusion
Effectiveness of Combining Erector Spinea Block With Non Opioid Infusions as Opioid Free Anesthesia in Spine Surgeries.
opioid free anesthesia consists of combination of pharmacological and non pharmacological modalities that target different pathways of pain mechanism.
- Trial name
- NCT05850468
- Testing
- fentanyl infusion after general anesthesia and erector spinea block, lidocaine 2% and dextometometidine infusion after general anesthesia and erector spinea block
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Knee Osteoarthritis, Hip Osteoarthritis
Regional Anesthesia in Total Hip and Knee Arthroplasty
The purpose of this study is to test whether the use of Ropivacaine and Mepivacaine are better in terms of effectiveness, cost, and safety than Bupivacaine as regional anesthetics in elective hip or knee replacement surgery.
- Trial name
- NCT04257682
- Testing
- Bupivacaine, Ropivacaine, Mepivacaine
- Volunteers
- 135 people
- Sponsor
- Ottawa Hospital Research Institute
Dental Anxiety, Pain
Efficacy of Tell-Show-Do Behavior-Management Technique During Local Anesthesia in Preschool Children
This will be a randomized, controlled, parallel-group clinical trial. The aim of this study will be to evaluate the effectiveness of "Tell-Show-Do" Behavior Management Technique versus a Conventional technique (covering the…
- Conditions
- Dental Anxiety, Pain, Infant Behavior, Heart Rate and Rhythm Disorders
- Trial name
- NCT02578160
- Testing
- inferior alveolar and lingual nerve block procedure
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Evelyn Alvarez Vidigal
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