Clinical trials: Anesthesia Effectiveness
Hypersalivation, Prevention of Drooling
Efficacy of Intravenous Glyco-P® in Patients Undergoing Procedure That Require Anesthesia Service
This observational study was designed to prove clinical efficacy of the well known "glycopyrrolate" which is considered an orphan drug in Thailand.
- Conditions
- Hypersalivation, Prevention of Drooling, Bradycardia, Reversal of Muscle Relaxants
- Trial name
- NCT02102542
- Where
- Thailand
- Volunteers
- 65 people
- Sponsor
- Mahidol University
Anesthesia
The Efficacy of Adding Dexmedetomidine Perineurally to Bupivacaine in Ultrasound Guided Fascia Iliaca Block Versus Intravenously Infused Dexmedetomidine on Hemodynamic Stability Intraoperatively and Postoperative Analgesia Following Hip Arthroscopy
The current study aims to assess effectiveness of dexmedetomidine as adjuvant to general anesthesia on the hemodynamic stability and narcotic consumption intraoperatively and its effect as adjuvant to fascia iliaca compartment…
- Trial name
- NCT04917029
- Testing
- Bupivacaine hydrochloride perineurally, Dexmedetmidine infusion, Dexmedetomidine perineurally
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Ain Shams University
Video Assisted Thoracic Surgery (VATS), Erector Spinae Plane Block
Efficacy of Erector Spinae Plane Block in Major Video-assisted Thoracic Surgery Compared to Intrathecal Morphine and Intercostal Nerve Block.
An ambispective observational study based on two groups (ITM and ICNB) from an earlier clinical trial conducted by our team(15) and a third group (ESPB) that received the new type of block, as we sought to assess the efficacy of…
- Conditions
- Video Assisted Thoracic Surgery (VATS), Erector Spinae Plane Block, Regional Anaesthesia, ERAS Programmes
- Trial name
- AESPVIMVIB (NCT07441161)
- Testing
- Spinal analgesia, regional block
- Where
- Spain
- Volunteers
- 113 people
- Sponsor
- Hospital Donostia
Post Operative Analgesia, Regional Anaesthesia
Comparison Between Paravertebral and Erector Spinal Block Efficacy in Robotic Thoracic Surgeries
The overall goal of this work is to find the preferred continues catheter- based thoracic block for patients who undergoing major ROBOTIC assisted thoracic surgery (Lobectomy, multiple segmental resection and thoracotomy).
- Conditions
- Post Operative Analgesia, Regional Anaesthesia, Pain After Surgery, Opioid Consumption
- Trial name
- TPVB vs ESP (NCT07782073)
- Testing
- Paravertebral Nerve Block, ESP block group
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Soroka University Medical Center
Pain Management, Local Anaesthesia
Effectiveness of DentalVibe in Reducing Injection Pain and Anxiety During Local Anaesthesia in Children
The aim of this study is to determine the effectiveness of DentalVibe (DV) in reducing injection pain and anxiety associated with local anaesthesia in paediatric patients.
- Trial name
- NCT03445182
- Testing
- Local anaesthesia with conventional syringe, Local anaesthesia with conventional syringe + Dentalvibe
- Where
- Bulgaria
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Anesthesia
Tranexamic Acid in Functional Endoscopic Sinus Surgery
The purpose of the study is to compare the effect of oral tranexamic acid vs. intravenous in decreasing bleeding and improving the field during FESS.
- Trial name
- NCT05686005
- Testing
- Oral tranexamic acid, Intravenous tranexamic acid
- Where
- Egypt
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
164 Boys for Hypospadias Surgery Under General Anesthesia With Caudal Block
Caudal Dexmedetomidine Analgesia in Pediatrics .
Dexmedetomidine (DEXM) is a highly selective α2-adrenoceptor agonist that has been used increasingly in pediatric anesthesia. This prospective double blinded randomized comparative study is designed to evaluate the analgesic…
- Trial name
- NCT03791879
- Testing
- Caudal dexamedatomidine analgesia
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Mansoura University
Analgesia Disorder, Anesthetic Complication Epidural
Effectiveness of Epidural Anesthesia for Thoracic and Abdominal Surgery
This study aims to evaluate the effectiveness of the epidural analgesia in patients having elective thoracic and abdominal surgery under general anesthesia combined with epidural analgesia in Siriraj Hospital.
- Conditions
- Analgesia Disorder, Anesthetic Complication Epidural, Adverse Reaction to Epidural Anesthesia
- Trial name
- NCT02315261
- Testing
- Elective Thoracic and Abdominal Surgery Patients
- Where
- Thailand
- Volunteers
- 364 people
- Sponsor
- Siriraj Hospital
Gastroscopy, Colonoscopy
A Trial to Evaluate the Efficacy and Safety of Methoxyethyl Etomidate Hydrochloride in Gastroscopy/Colonoscopy
A total of 78 subjects undergoing gastroscopy/colonoscopy were randomly assigned to the methoxetomidate hydrochloride group and the etomidate group according to the ratio of 1:1:1 with etomidate as the control group, 26 cases in…
- Trial name
- NCT06682546
- Testing
- ET-26HCl 0.6mg/kg group, ET-26HCl 0.8mg/kg group, Etomidate Injectable Product 0.3mg/kg group
- Where
- 3 sites in China
- Volunteers
- 78 people
- Sponsor
- Ahon Pharmaceutical Co., Ltd.
Irreversible Pulpitis, Tooth Extraction
Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients
To evaluate the effectiveness of intra-osseous anesthesia using Quicksleepr5 in pain elimination during dental treatment in maxillary and mandibular primary molars, compared to conventional anesthesia.
- Trial name
- NCT06245161
- Testing
- Quicksleeper5, conventional anesthesia
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dental Fear, Anesthesia, Local
Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children
Dental Fear and Anxiety (DFA) are at higher levels among children and often leads to avoidance of dental treatment. Negative experiences in the early years such as experience of pain during injections, fillings, or extractions…
- Conditions
- Dental Fear, Anesthesia, Local, Pediatric Dentistry
- Trial name
- NCT03779659
- Testing
- Synapse TENS device, Topical anesthetic gel
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston University
Anesthesia, Radical Mastectomy
Analgesic Efficacy of Ultrasound Guided Serratus Anterior Plane Block and Pectoral Nerve Block II
Modified Radical Mastectomy accounts for 31% of all breast surgeries and considered the fundamental surgical management for breast cancer. Nearly 40-60% of patients experience severe acute postoperative pain.
- Trial name
- NCT06188156
- Testing
- Anethesia
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Al-Azhar University
Adverse Effect
90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment
The objective of this study is to investigate the 90% effective dose of phenylephrine infusions for preventing postspinal anesthesia hypotension under intensive and standard treatment during cesarean section
- Trial name
- NCT06151522
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Erector Spinae Plane Block, Lower Extremity Surgery
Regional Anesthesia for Lower Extremity Surgery
In this study, patients who underwent osteosynthesis with plate via standard anterolateral incision due to proximal tibia fracture in the orthopedic clinic within the last year; those who underwent perioperative anesthesia with…
- Conditions
- Erector Spinae Plane Block, Lower Extremity Surgery, Sciatic Nerve Block
- Trial name
- NCT06777953
- Testing
- Erector Spinae (ESP) Block with Lidocaine/Bupivacaine, Popliteal Sciatic Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Haseki Training and Research Hospital
Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV)
Dexamethasone to Prevent Side Effects of Spinal Anesthesia in Cesarean Delivery
The goal of this clinical trial is to evaluate the effectiveness of intravenous dexamethasone in preventing adverse effects of spinal anesthesia and prolonging postoperative analgesia in parturients undergoing elective cesarean…
- Conditions
- Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV), Pain, Postoperative
- Trial name
- NCT07615595
- Testing
- Dexamethasone
- Where
- Vietnam
- Volunteers
- 176 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Local Anesthesia
Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection
This study will test the effectiveness of addition of Sodium Bicarbonate as a buffering agent to the anaesthetic solution on minimizing the pain of injection and increasing the onset time and potency of the anaesthetic solution…
- Trial name
- NCT05473819
- Testing
- Buffered Local Anesthesia, Conventional Unbuffered Local Anesthesia
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Internal Derangement of Hip, Acetabular Labrum Tear
Preemptive Femoral & Lateral Femoral Cutaneous Nerve Blocks for THA Acute Pain
The goal of the study is to evaluate via a prospective, blinded, randomized clinical trial, whether ultrasound-guided single femoral and lateral femoral cutaneous nerve blocks with ropivacaine 0.5% with epinephrine (1:200,000) as…
- Trial name
- NCT01997567
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Rush University Medical Center
Arthropathy of Hip
Compare Epidural vs. Lumbar Plexus Analgesia After Hip Arthroplasty
The goal of this retrospective chart review is to evaluate if the implementation of lumbar plexus block placement for postoperative pain have improved conditions in the postoperative period for patients undergoing total hip…
- Trial name
- NCT02493621
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Bronchoscopy, Anesthesia, Local
5 Versus 10 Sprays of Lignocaine for Pharyngeal Anaesthesia During Bronchoscopy
Flexible bronchoscopy is one of the most widely performed procedures for diagnosis of various bronchopulmonary diseases. Most patients tolerate the procedure well although cough is often reported as a distressing symptom.
- Trial name
- NCT03869528
- Testing
- 5 sprays of 10% lignocaine, 10 sprays of 10% lignocaine
- Where
- 2 sites in India
- Volunteers
- 300 people
- Sponsor
- All India Institute of Medical Sciences
Sore Throat, Cough
Comparing the Efficacy Between Lignocaine Given Via MADgic Atomizer and Lignocaine Pump Spray
Comparing the efficacy between Lignocaine given via MADgic Atomizer and Lignocaine Pump Spray pre endotracheal intubation in adult undergoing General Anesthesia.
- Conditions
- Sore Throat, Cough, Hoarseness, Hemodynamic Instability
- Trial name
- NCT06213116
- Testing
- MADgic Atomizer, Lignocaine pump spray
- Where
- Malaysia
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
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