Clinical trials: Anesthesia Management
Local Anesthesia
Safety and Efficacy Study of an Iontophoretic Patch Containing Lidocaine and Epinephrine for Venipuncture in Healthy Adult Volunteers
The purpose of this study is to evaluate the effectiveness of administering Lidocaine and Epinephrine using an iontophoretic device treatment to provide local anesthesia to healthy adult volunteer subjects undergoing venipuncture.
- Trial name
- NCT00889642
- Testing
- Iontophoretic Drug Delivery System with Lidocaine/Epinephrine, Iontophoretic Drug Delivery System with Epinephrine
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dharma Therapeutics Inc.
Postoperative Airway Complications
The Impact of Endotracheal Cuff Pressure Assessment Using a Cuff Pressure Manometer Compared With the Traditional Palpation Method on Postoperative Outcomes
The aim of this prospective observational study is to evaluate the effect of endotracheal cuff pressure management on postoperative complications in patients undergoing surgery under general anesthesia.
- Trial name
- ECP (NCT07427173)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Analgesia, Post Operative Pain
Clinical Utility of the Numerical Verbal Scale (NVS) and the Pain and Functional Activity Scale (PFAS) in the Management of Rescue Analgesia in Acute Postoperative Pain. Randomized Study.
Adequate postoperative pain management, along with mobilization and early oral nutrition, is the foundation for optimal recovery after surgery.
- Conditions
- Analgesia, Post Operative Pain, Acute Pain, Functional; Anesthesia
- Trial name
- EVN/EDAF (NCT07310953)
- Testing
- Group A: Rescue analgesia if NVS>4, Group B: Rescue analgesia if NVSm > 4 + FAS C
- Where
- Spain
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Postoperative Pain Management
Ultrasound-guided Erector Spinae Plane Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia of Adult Patients Undergoing Ovarian Cancer Surgery
Postoperative pain is one of the greatest patient concerns following any surgery. Although an increased emphasis has been placed on pain management, approximately 80% of surgical patients report postoperative pain with 86% of…
- Trial name
- NCT04434339
- Testing
- erector spinae block, transversus abdominis block
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Analgesia, Pain, Postoperative
Comparison Between the Caudal Block and Other Methods of Postoperative Pain Relief in Children Undergoing Circumcision
Prospective, randomized, case-controlled trial study. Observation post-operatively: Aims: This study aimed to compare the effectiveness of the caudal block CB with other methods of postoperative pain release.
- Conditions
- Analgesia, Pain, Postoperative, Pain, Acute
- Trial name
- paincontrol (NCT06086106)
- Testing
- caudal block, Dorsal Penile Nerve Block DPNB, Systemic opioids
- Where
- Bahrain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Salmaniya Medical Complex
Pain, Postoperative
Regional Anesthesia for Head and Neck Reconstruction
By utilizing regional anesthesia blocks at the surgery tissue donor sites, it can potentially reduce post-operative pain while also reducing the use of opioids.
- Trial name
- NCT04304716
- Testing
- Regional Anesthesia
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Effectiveness of Anesthesia Using Electronic Syringe in Children in the Context of Endotopy Treatment
Effectiveness of Intraligament vs IANB Anesthesia in Children Using Electronic Syringe
This randomized clinical study aims to evaluate the efficacy and pain response of two local anesthesia techniques in pediatric dental treatment using an electronic syringe: ligament anesthesia and inferior alveolar nerve block…
- Trial name
- NCT07095946
- Testing
- Electronic Syringe Intraligament Technique, Electronic syringe IANB Technique
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Latakia University
Postoperative Pain, Psychological Factors
Psychosocial Factors and Postoperative Pain in Aesthetic Breast Surgery
This study investigates the relationship between psychosocial factors, particularly self-esteem and personality traits, and postoperative pain in patients undergoing aesthetic breast surgery.
- Conditions
- Postoperative Pain, Psychological Factors, Breast Surgery, Aesthetic Surgery
- Trial name
- NCT06707818
- Testing
- Preoperative Interventions, Intraoperative Interventions, Postoperative Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- V.K.V. American Hospital, Istanbul
Anesthesia, Local
Effectiveness of Buccal Infiltration During Vital Pulpotomy After Administering Two Analgesic Premedications
This Randomized study was designed to assess and compare the effect of two analgesic premedications (Ibuprofen BP 100 mg/5 ml and Paracetamol 200 mg/5ml.) on the anesthetic efficacy of buccal infiltration in vital pulpotomy of…
- Trial name
- NCT03423329
- Testing
- Brufen, Cital
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia, Consensus Development
Anesthesia Core Quality Metrics Consensus Delphi Study
To develop a ranked list of up to 20 metrics, which can be used to evaluate the quality of anesthesia, perioperative care, and acute pain management for adult inpatient non-cardiac surgical patients for use in quality improvement…
- Trial name
- NCT05386082
- Testing
- Modified Delphi process
- Where
- 3 sites in Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pelvic Floor Disorders
Factors Influencing Hemodynamic Stability and Its Management in Patients Undergoing Pelvic Surgery Under Spinal and GA
Patients are at risk for hemodynamic instability both during and after surgery, as it is an independent predictor of long-term patient morbidity and length of hospital stay.
- Trial name
- NCT06767397
- Testing
- general anesthesia
- Where
- Pakistan
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Superior University
Anesthesia; Adverse Effect, Cardiac Arrhythmia
Effects of HSK3486 on Cardiac Repolarization in Health Subjects (TQT)
To assess the effects of a single IV bolus of HSK3486 single dose on cardiac repolarization (QTc interval of the electrocardiogram, and to evaluate the safety and tolerability of a single IV bolus of HSK3486 in healthy subjects
- Trial name
- NCT06795204
- Testing
- HSK3486, Moxifloxacin Hydrochloride
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Haisco-USA Pharmaceuticals, Inc.
Dental Anxiety
Effectiveness Of Magic Tricks Distraction Technique
Dental anxiety among children is a significant challenge in pediatric dentistry, often hindering effective dental care. This clinical study aims to evaluate the effectiveness of two magic tricks distraction techniques (magic rope…
- Trial name
- NCT07075458
- Testing
- Magic Rope Trick, Magic Thumb Sleeves, Tell-Show-Do (TSD)
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pain
The Effectiveness of Sweet Solution Versus Cryotherapy in Reducing Pain During Administration of Local Anesthesia Among Children
the porpose of study to assess The Effectiveness of Sweet Solution Versus Cryotherapy in Reducing Pain During Administration of Local Anesthesia Among Children
- Trial name
- NCT07002528
- Testing
- sucrose solution, Cryotherapy, topical anesthesia
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Local Anaesthesia
Intradermal Lidocaine Via MicronJet600 Microneedle Device
The purpose of this study is to determine efficiency and safety of injecting a micro-amount of 2% lidocaine with the commercially available microneedle device MinronJet600 (NanoPass Technologies Ltd, Israel) (registration number…
- Trial name
- NCT05108714
- Testing
- Intravenous cannulation after intradermal injection of lidocaine via MicronJet600 microneedle device (1), Intravenous cannulation after intradermal injection of saline via MicronJet600 microneedle device, Intravenous cannulation after intradermal injection of lidocaine via MicronJet600 microneedle device (2)
- Where
- Russia
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Postoperative Pain
ESP vs QL for Total Abdominal Hysterectomy
Patients undergoing open total abdominal hysterectomy (n=82) at Parkland Memorial Hospital will be randomized into one of two groups to receive either ultrasound-guided bilateral ESP block with liposomal bupivacaine (Group 1) or…
- Trial name
- NCT04074226
- Testing
- Erector Spinae Plane block, Quadratus Lumborum Block
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Intubation; Difficult or Failed, Airway Complication of Anesthesia
Neural Integrity Monitor Electromyogram (NIM-EMG) Endotracheal Tube Intubation With Video Laryngoscope
Laryngeal nerve monitoring is performed to prevent intraoperative nerve damage in thyroidectomy operations. NIM-EMG intubation tube is used while monitoring the recurrent laryngeal nerve.
- Conditions
- Intubation; Difficult or Failed, Airway Complication of Anesthesia, Pain, Postoperative, Anesthesia Intubation Complication
- Trial name
- NCT05366582
- Testing
- Macintosh Laryngoscope, Video Laryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Laparoscopic Surgery, PONV
Effects of Auricular Acupressure on the Management of Postoperative Nausea and Vomiting After Gynecological Laparoscopic Surgeries
Auricular acupressure is easily accessible and easily performed, and can significantly relieve PONV symptoms, and improve patient's satisfaction in women receiving general anesthesia for gynecological surgeries.
- Conditions
- Laparoscopic Surgery, PONV, Auricular Acupressure
- Trial name
- NCT05540236
- Testing
- auricular acupressure
- Where
- Taiwan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Cathay General Hospital
Atropine Bioequivalence
Sublingual Atropine Bioequivalence by Route of Administration (SABER)
A randomized, two-period, two-sequence, crossover study to assess the bioequivalence, bioavailability, and pharmacokinetics (PK) of a single dose of atropine administered sublingually (SL) or intramuscularly (IM) in healthy adult…
- Trial name
- SABER (NCT06366087)
- Testing
- Atropine Sulfate Ophthalmic Solution USP, 1%, Atropine Sulfate Injection, USP 8 mg/20 mL (0.4 mg/mL)
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Biomedical Advanced Research and Development Authority
Pain
Pain Management Following Dental Treatment Under General Anesthesia
The main goal of this study is to test the efficacy of postoperative pain management for cases undergoing extractions of primary teeth under GA using a validated measure.
- Trial name
- NCT06574516
- Testing
- Ibuprofen 200 mg, paracetamol
- Where
- Jordan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital