Clinical trials: Anesthesia Management
Intraoperative Neurophysiological Monitoring, Pain Management
Effect of a Bolus of Clonidine Systemically Administered on the Excitability of the Spinal Motoneurons of the Lower Extremity
The purpose of this study is to assess the effect of IV clonidine administration on lower limb spinal motoneuron excitability during standardized total intravenous anesthesia (propofol and remifentanil).
- Trial name
- EXCICLON (NCT02592915)
- Testing
- Clonidine hydrochloride, Single bolus of physiologic sodium chloride serum administered IV after induction and obtaining a stable anaesthetic level
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Queen Fabiola Children's University Hospital
Global Warming Effect of Nitrous Oxide
Global Warming Impact of Nitrous Oxide
Environmental hazards of human activity are a topic of present day world, global warming being one of the leading concerns. Gases that contribute to this are greenhouse gases.
- Trial name
- NCT05430750
- Testing
- Nitrous oxide, Sevoflurane
- Where
- India
- Volunteers
- 102 people
- Sponsor
- Sir Ganga Ram Hospital
Airway Management, General Anesthesia
Comparison of Three Airway Intubation Devices for First-Attempt Success in General Anesthesia Patients
The goal of this clinical trial is to compare three airway intubation devices in adult patients undergoing general anesthesia who require tracheal intubation.
- Conditions
- Airway Management, General Anesthesia, Tracheal Intubation
- Trial name
- NCT07699653
- Testing
- SPHJ-II, Video lighted stylet, Visual intubation fiberscope
- Where
- China
- Volunteers
- 542 people
- Sponsor
- Guangzhou University of Chinese Medicine
Postoperative Sore Throat, Endotracheal Intubation
Scheduled Endotracheal Tube Cuff Pressure Management and Postoperative Sore Throat
This randomized controlled trial evaluated whether scheduled measurement and adjustment of endotracheal tube cuff pressure using a handheld manometer could reduce postoperative sore throat in adults undergoing elective surgery…
- Trial name
- NCT07842081
- Testing
- Handheld Endotracheal Tube Cuff Manometer, Pilot-Balloon Palpation
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Hitit University
Nephrolithiasis
Postoperative Analgesia Practices After Percutaneous Nephrolithotomy
This prospective observational study aims to evaluate the effectiveness and safety of different postoperative analgesia methods used in patients undergoing percutaneous nephrolithotomy (PCNL).
- Trial name
- NCT07258901
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istinye University
Anesthesia, General
Manual Administration of Propofol-remifentanil Versus Dual Closed-loop Using Bispectral Index as the Control Variable
To compare manual administration of propofol and remifentanil and dual closed-loop using bispectral index as the control variable during anesthesia
- Trial name
- NCT00392158
- Testing
- Closed-loop anesthesia system
- Where
- 6 sites in France
- Volunteers
- 240 people
- Sponsor
- Hopital Foch
Pain Management, Perioperative Analgesia
From Battlefield to Recovery: Continuous Regional Anaesthesia for War-Related Lower Limb Trauma
To compare the effectiveness of continuous regional anaesthesia with standard pain management strategies for the treatment of acute pain in patients with war-related lower limb trauma.
- Conditions
- Pain Management, Perioperative Analgesia, War-Related Injuries
- Trial name
- CRA-WAR-LIMB S (NCT07474506)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Spinal Anesthesia for Cesarean Section
Comparison of Fractionated Versus Bolus Administration of Different Doses of Hyperbaric Bupivacaine Combined With Opioids in Spinal Anesthesia for Caesarean Section
This study aimed to compare the effectiveness and safety of fractionated versus bolus administration of different doses of hyperbaric bupivacaine (0.06 and 0.07 mg/cm height) combined with opioids in spinal anesthesia for…
- Trial name
- NCT07249814
- Testing
- Fractionated anesthesia, Bolus anesthesia
- Where
- Ukraine
- Volunteers
- 99 people
- Sponsor
- Bogomolets National Medical University
Virtual Reality, Pain, Postoperative
Virtual Reality for Post Operative Pain Management After Total Knee Arthroplasty
Virtual reality has been used for acute pain management (burn patients) with positive results. Hypnosis has known beneficial effects on patients in the peri-operative setting.
- Conditions
- Virtual Reality, Pain, Postoperative, Knee Arthropathy, Anesthesia
- Trial name
- VR4POPKA (NCT03665233)
- Testing
- VR
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Clinique Saint-Jean, Bruxelles
Post-Dural Puncture Headache, Headache
Sphenopalatine Ganglion Block for Post-Dural Puncture Headache
This pilot randomised controlled trial compared sphenopalatine ganglion block (SPGB) using intranasal 2% lidocaine versus conservative management (bed rest and aggressive hydration) in patients who developed post-dural puncture…
- Trial name
- NCT07494383
- Testing
- Sphenopalatine ganglion block, Conservative management
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- ISSSTE Hospital Regional "Gral. Ignacio Zaragoza"
Behavior, Child, Dental Anxiety
Dental Attire Effect on Children's Dental Anxiety
The aim of this study is to evaluate the effect of friendly attire on dental anxiety among children visiting dental office in comparison with conventional attire.
- Conditions
- Behavior, Child, Dental Anxiety, Anesthesia, Local
- Trial name
- NCT06122883
- Testing
- Evaluation the effectiveness of distraction in the reception area in the management of anxious pediatric patients during dental local anesthesia, Evaluation the effectiveness of distraction in the treatment area in the management of anxious pediatric patients during dental local anesthesia, Evaluation the effectiveness of distraction in both reception and treatment areas in the management of anxious pediatric patients during dental local anesthesia
- Where
- Syria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Damascus University
Pain After Total Knee Arthroplasty, Pain Management
Combined Distal Femoral Nerve Block for Pain Control After Knee Replacement
The goal of this clinical trial is to see whether a combined distal femoral nerve block improves pain relief after total knee replacement in adults having planned surgery.
- Trial name
- FEM-COMB (NCT07629388)
- Testing
- Combined distal femoral nerve block, Saphenous nerve block alone, Standard perioperative care in both groups
- Where
- France
- Volunteers
- 240 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Pulpitis
Efficacy of Oral Prednisolone on Pain Reduction in Emergency Care of Acute Irreversible Pulpitis
Irreversible pulpitis is an inflammatory condition of the dental pulp, highly painful, representing one of the main reasons for consulting dental emergency.
- Trial name
- PULPISOLONE (NCT02629042)
- Testing
- Partial endodontic treatment under local and/or locoregional anesthesia, prednisolone
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Bordeaux
Toxicology, Bariatric Surgery Analgesia
Preoperative Toxicological Screening on Perioperative Anesthetic Management
Background: Preoperative substance use is a growing concern in patients undergoing metabolic bariatric surgery (MBS), but its impact on short-term outcomes remains debated.
- Conditions
- Toxicology, Bariatric Surgery Analgesia, Bariatric Surgery, Substance Use
- Trial name
- NCT07100314
- Testing
- Multi-Drug One Step Screen Test Panel (Urine)
- Where
- Egypt
- Volunteers
- 1,260 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Anesthesia, Sevoflurane
MAAS Method (Minimal-flow Auto-control Anesthesia System) for the Administration of Desflurane and Sevoflurane
In the present work the investigators will study the accuracy of the MAAS (Minimal-flow Autocontrol Anesthesia System) method to estimate the percentage of halogenated anesthetic (HA) to be supplied to the anesthetic circuit…
- Conditions
- Anesthesia, Sevoflurane, Desflurane, Low Flow Anesthesia
- Trial name
- MAAS (NCT05511610)
- Testing
- Sevoflurane uptake and supply, Washout phase, Desflurane uptake and supply
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Cesarean Section
Fluid Management for Cesarean Section
Cesarean section-associated hypotension is one of the pivotal factors to influence the Apgar Score of children and related with the stable hemostasis during the whole process of labor.
- Trial name
- FMCS (NCT00488111)
- Testing
- Ringer's Lactate, 6% Starch
- Where
- China
- Volunteers
- 850 people
- Sponsor
- Nanjing Medical University
Anesthesia Airway Management
Comparison Study of Two Supraglottic Airway Devices Used for Patients Under General Anesthesia
This study will compare two supraglottic airway devices currently on the market. Supraglottic airway devices are used during general anesthesia to provide a patent airway.
- Trial name
- NCT01001078
- Testing
- I-Gel supraglottic airway device, LMA Supreme supraglottic airway device, Standard endotracheal tube
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital
Esophageal Cancer, Postoperative Pulmonary Atelectasis
High Flow Nasal Cannula After Esophagectomy
This study will compare the effect of HFNC versus standard oxygen administration after elective esophagectomy for cancer.
- Conditions
- Esophageal Cancer, Postoperative Pulmonary Atelectasis, Postoperative Pneumonia, Postoperative Pneumothorax
- Trial name
- OSSIGENA1V (NCT05718284)
- Testing
- AIRVO2, STANDARD CARE
- Where
- Italy
- Volunteers
- 320 people
- Sponsor
- Cristian Deana
Anesthesia, Local, Eyelid Diseases
Transconjunctival vs Transcutaneous Anaesthesia in Oculoplastics
Eyelid surgery is commonly performed under local anaesthesia. For many such procedures, the local anaesthetic injection may be given either transcutaneously (through the skin) or transconjunctivally (through the conjunctiva, i.e.
- Trial name
- NCT04102878
- Testing
- Topical Anesthetic, Transconjunctival anaesthetic, Transcutaneous anaesthetic
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
General Anesthesia
Population Pharmacokinetics and Clinical Individual Dosage Regimen of Propofoll Injection
Propofol is a widely used sedative anesthetic, but there are large individual differences, which making different patients with different sensitivity to propofol.
- Trial name
- NCT03422315
- Testing
- Propofol
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhongyuan Xu