Clinical trials: Anesthesia Management
Comparison of Airway Management Techniques in Functional Endoscopic Sinus Surgery, Rhinosinusitis With Polyps
Comparison of Laryngeal Mask and Tracheal Intubation With and Without Topical Lidocaine Application
The study aims to identify the advantages and disadvantages of each of the three methods of airway management during FESS.
- Conditions
- Comparison of Airway Management Techniques in Functional Endoscopic Sinus Surgery, Rhinosinusitis With Polyps, Deviated Nasal Septum, Osteoma of the Paranasal Sinuses
- Trial name
- NCT07548866
- Testing
- anesthesia of the respiratory tract with lidocaine, tracheal intubation, laryngeal mask placement
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Endoscopy, Digestive System, Airway Anesthesia
Evaluating the Efficiency and Tolerability of the Oxygenating Bite Block
This study will test an investigational bite block, which is a device placed inside the mouth to protect the teeth and used to keep the endoscope (a long, flexible tube that is placed down the throat and into the esophagus that…
- Conditions
- Endoscopy, Digestive System, Airway Anesthesia, Airway Control, Airway Management
- Trial name
- OBB (NCT07086378)
- Testing
- Oxygenating Bite Block
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cedars-Sinai Medical Center
Adult, Anesthesia, General
Anesthesia Induction With Intravenous Bolus or Continuous Infusion of Remimazolam
Bolus injection and continuous infusion are two widely used methods for intravenous administration of drugs. Bolus injection possibly leads to a rather high drug plasma concentration temporarily, however, it can induce a rapid…
- Trial name
- NCT05423080
- Testing
- Bolus injection of remimazolam, Infusion of remimazolam
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Korea University Guro Hospital
Pain Management, Anaesthesia Complication
Efficacy of Variable Volume Truncal Blocks in Upper Limb Orthopedic Surgery
aim of this study is to compare the effect of selective truncal blocks, performed at different doses and volumes, on the onset times of motor and sensory blocks required for anesthesia in patients scheduled for hand, wrist…
- Trial name
- NCT06664203
- Testing
- Selective turuncus block with 25 ml bupivacain, Selective turuncus block with 15 ml bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Post Spinal Anesthesia Shivering
The Effect of Different Doses of Dexamethasone on Post Spinal Anesthesia Shivering
The precise etiology of post-spinal anesthesia shivering (PSAS) is not fully understood. The incidence ranges between 20 to 80%.
- Trial name
- NCT06999070
- Testing
- Dexamethasone 0.1mg/kg, Dexamethasone 0.3mg/kg
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain Management, Total Knee Arthroplasty
Efficacy of Combined Adductor and Tibial Nerve Blocks for Pain Management in Knee Arthroplasty
This study aims to explore methods for enhancing pain relief following knee replacement surgery, a prevalent procedure for individuals with severe knee arthritis.
- Conditions
- Postoperative Pain Management, Total Knee Arthroplasty, Regional Anesthesia, Nerve Blocks
- Trial name
- CATNAP (NCT06552897)
- Testing
- Intervention 1: Adductor Canal Block (ACB), Intervention 2: Combined Adductor Canal Block and Selective Tibial Nerve Block (ACB + STNB)
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara City Hospital Bilkent
Hypotension Drug-Induced, Anesthesia
Pre-op Fluid Study
Theoretical framework: Hypotension during surgery directly impacts patients' postoperative outcomes and complications. Decrease in blood pressure measurements secondary to anesthetic drugs is an expected scenario in most surgical…
- Trial name
- NCT05079269
- Testing
- Crystalloid Solutions
- Where
- 2 sites in Austria
- Volunteers
- 550 people
- Sponsor
- Medical University of Graz
General Anesthesia
Design of a Closed-loop Controller Based on the Bispectral Index (BIS) Effectiveness of the Smith Predictor
The action of anesthetics such as propofol is not immediate after intravenous administration. Delay in pharmacodynamic effect of intravenous drugs is a commonly observed phenomenon in total intravenous anesthesia (TIVA).
- Trial name
- NCT03073408
- Testing
- Propofol
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- José Antonio Reboso Morales
Abdominal Hysterectomy, General Anesthesia
Intravenous Administration of Magnesium Sulfate in Hysterectomy Cases
In our study, it was aimed to show the contribution of intraoperative intravenous magnesium sulfate administration to peroperative opioid consumption and postoperative analgesia.
- Conditions
- Abdominal Hysterectomy, General Anesthesia, Magnesium Sulfate
- Trial name
- NCT05644873
- Testing
- magnesium sulfate group, control group saline
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Infant Apnea, Surgical Procedure, Unspecified
Apneic Oxygénation by Nasal Canula During Infants Airway Management Study
This is a randomized clinical trial investigating the utility of apneic oxygenation via high flow nasal cannulae during airway management for infants general anaesthesia.
- Conditions
- Infant Apnea, Surgical Procedure, Unspecified, Airway Management
- Trial name
- Oxyeno (NCT03967769)
- Testing
- High Flow nasal Cannula
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Clermont-Ferrand
Postoperative Pain
Abdominal Wall Local Anesthesia to Maximize Postoperative Pain Control After Cesarean Delivery
This study has been designed to determine if women undergoing cesarean delivery with spinal anesthesia and routine pain management who also have an additional ultrasound guided transversus abdominis plane (TAP)block using…
- Trial name
- NCT01261637
- Testing
- Ropivicaine
- Where
- Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Epidural Anesthesia
Effect of Intraoperative Fluid Management on Morbidity
The purpose of this study is to determine whether intraoperative fluid and sodium restriction decreases postoperative morbidity
- Trial name
- NCT00156338
- Testing
- fluid management
- Where
- 3 sites in Germany
- Volunteers
- 108 people
- Sponsor
- University Hospital Muenster
Ultrasonography, Airway Management
Evaluation of Anterior Neck Ultrasound in Predicting Difficult Airway in Obese Patients
Obese patients are at increased risk of difficult airway management due to anatomical changes in the anterior neck soft tissues.
- Conditions
- Ultrasonography, Airway Management, Intubation, Intratracheal, Obesity and Overweight
- Trial name
- NCT07346768
- Testing
- None (Observational study)
- Volunteers
- 52 people
- Sponsor
- Gaziantep City Hospital
Cesarean Section, Cardiac Output
Best Regimen for Phenylephrine Administration During Cesarean Section
During Cesarean delivery, phenylephrine is used to maintain the patient's blood pressure. Low blood pressure is the most common side effect of the spinal medication used to anesthetize the patient prior to the start of surgery.
- Conditions
- Cesarean Section, Cardiac Output, Hypotension
- Trial name
- NCT00996190
- Testing
- Phenylephrine
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pain Management
Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery
Opioids are prescribed for moderate to severe pain disorders; however, there are contraindications and side effects that are common to all opioids.
- Trial name
- NCT03757715
- Testing
- Bupivacaine, Dexamethasone
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama at Birmingham
Post-operative Pain, Total Shoulder Arthroplasty
LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs
This will be a single-center, prospective, randomized controlled cross-sectional study comparing interscalene brachial plexus block with liposomal bupivacaine versus bupivacaine with epinephrine and PF dexamethasone in patients…
- Conditions
- Post-operative Pain, Total Shoulder Arthroplasty, Osteoarthritis of the Shoulder, Pain Management
- Trial name
- NCT03887650
- Testing
- Liposomal Bupivicaine 1.3%, Bupivacaine 0.5%
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Hartford Hospital
Pediatric Patients, Orthopedic Surgery
Nociception Level Index as a Verbal Tool of Pain in Children
60 children under 6 years old, scheduled for orthopedic surgery for limb fracture or neuromuscular and bone deformities will be randomized by closed envelope method into two groups (n=30) either receiving standard pain management…
- Conditions
- Pediatric Patients, Orthopedic Surgery, Extremity Fractures Lower, Extremity Fractures Upper
- Trial name
- NCT05716243
- Testing
- The nociception level index monitorization, The nociception level index measurement;postoperative
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
Spinal Anesthesia, Cesarean Section Pain
Effect of Single-Dose Dexamethasone on Postoperative Pain After Cesarean Section Under Spinal Anesthesia
This study looked at whether giving a single dose of dexamethasone (a steroid medicine, 8 mg given into the vein) before a cesarean section could reduce pain after the operation.
- Conditions
- Spinal Anesthesia, Cesarean Section Pain, Postoperative Pain
- Trial name
- NCT07718360
- Testing
- Dexamethasone (IV), Normal Saline 0.9% Infusion Solution
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- KRL Hospital, Islamabad
Endotracheal Intubation, Gastrointestinal Endoscopy
Application of Lateral Position Digestive Endoscopy-Guided Endotracheal Intubation in Anesthesia for Endoscopic Diagnosis and Therapy
This case series study evaluated whether placing a breathing tube using a camera (gastrointestinal endoscope) is safe and effective for patients lying on their left side during stomach and intestine exams under anesthesia.
- Conditions
- Endotracheal Intubation, Gastrointestinal Endoscopy, Airway Management, Lateral Position
- Trial name
- NCT06990490
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Changlong Qiao
Pain, Postoperative, Osteoarthritis, Knee
Comparing Local Anesthetic Injections to Nerve Blocks for Pain Control After Total Knee Replacement
Why are we doing this study? People who have knee replacement surgery often feel pain afterward. Doctors use different methods to control this pain.
- Conditions
- Pain, Postoperative, Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Trial name
- LIA-PNB-TKA (NCT07744503)
- Testing
- Continuous Femoral and Sciatic Nerve Block (Ropivacaine), Local Infiltration Analgesia (Ropivacaine, Ketorolac, Epinephrine)
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Christopher Male