Clinical trials: Anesthesia Management
Shoulder Arthritis, Anesthesia, Local
Perioperative Pain Management for Total Shoulder Arthroplasty: A Pilot Non-Inferiority Trial
Total shoulder arthroplasty (TSA) is a common and effective treatment for end-stage shoulder pathologies. Over the past 25 years, implant designs have evolved and the indications for joint replacement have expanded significantly…
- Conditions
- Shoulder Arthritis, Anesthesia, Local, Local Infiltration
- Trial name
- NCT05908851
- Testing
- 100 mL of 0.9% normal saline (57ml), 0.5% ropivacaine (40 ml), 10 mg morphine (10 mg/ml), 0.1 mg of epinephrine (0.1 mg/ml), and 30 mg of ketorolac (30 mg/ml)
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postdural Puncture Headache (PDPH), Treatment Adherence and Compliance
Brochure-Supported Telemedicine Management of Postdural Puncture Headache
This study evaluates whether brochure-supported structured telemedicine counseling improves the management of postdural puncture headache after cesarean delivery under spinal anesthesia.
- Conditions
- Postdural Puncture Headache (PDPH), Treatment Adherence and Compliance, Cesarean Delivery Procedures
- Trial name
- Brochure-Suppo (NCT07708701)
- Testing
- Standard Information and Standard Telephone Follow-up, Brochure-Supported Structured Telemedicine Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Yuzuncu Yil University
Airway Management, Endotracheal Intubation
The Effect of Different Methods of Airway Management on the Stomatognathic System: an Observational Prospective Study.
The manipulations required during airway management and the different methods of establishing an airway (endotracheal intubation, supraglottic airway device etc) during anesthesia, as well as certain drugs used during anesthesia…
- Conditions
- Airway Management, Endotracheal Intubation, Supraglottic Airway Device, Regional Anesthesia
- Trial name
- NCT05783128
- Testing
- Airway management techniques (exposure)
- Where
- Greece
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Aretaieio Hospital
Regional Anesthesia, Lidocaine Infusion
Perioperative Use of Erector Spinae Plane Block (ESPB) and Intravenous Lidocaine Infusion in Anesthetic Management of Spinal Surgery in Children
Testing the hypothesis that in children undergoing spinal surgery, ESP-block will increase the time to emergency anesthesia in the postoperative period compared with intravenous lidocaine infusion.
- Trial name
- NCT06965933
- Testing
- ESP block group, IV Lidocaine
- Where
- Russia
- Volunteers
- 68 people
- Sponsor
- Saint Petersburg State University, Russia
Postoperative Pain
Effectiveness of TAP Block Versus Intravenous Analgesia in Postoperative Pain Management Following Gynecologic Laparoscopic Surgery
Optimal postoperative pain control is crucial in laparoscopic gynecologic surgery, particularly within Enhanced Recovery After Surgery (ERAS) protocols.
- Trial name
- NCT07051499
- Testing
- TAP Block Group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Foggia
Lactating Women
A Study to Assess the Transfer of Fospropofol and Its Active Metabolite, Propofol, to Breast Milk Following Administration of LUSEDRA to Lactating Women Undergoing a Needed Procedure
The purpose of this study is to assess the transfer of fospropofol and its active metabolite, propofol, to breast milk following administration of LUSEDRA® to lactating women undergoing a needed procedure.
- Trial name
- NCT01309984
- Testing
- Lusedra, Propofol
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Eisai Inc.
Pain, Postoperative, Osteoarthritis, Knee / Osteoarthritis, Hip
iPACK Block vs. Periarticular Infiltration for TKA Pain Control
This study aims to retrospectively compare two different multimodal analgesic techniques for pain management after total knee arthroplasty (TKA).
- Trial name
- NCT07267650
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Turgutlu State Hospital
School Age Children, Dental Fear
Tell-Show-Do for Reducing Dental Anxiety During Local Anesthesia
Dental anxiety is common in children and may increase during local anesthesia administration. Dental injection anxiety is one of the most frequently reported causes of dental anxiety in pediatric dental patients.
- Trial name
- NCT07626008
- Testing
- Early Tell-Show-Do Dental Injector Demonstration Sequence, Delayed Tell-Show-Do Dental Injector Demonstration Sequence
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Airway Management, Obesity
Comparison of Air QTM Intubating Airway Versus Ambu-Aura Intubating Laryngeal Mask
Supraglottic airway devices are important tools for airway management. Supraglottic airway devices have been introduced into brief surgical interventions because they are less invasive than intubation and safer than mask to…
- Trial name
- NCT04195035
- Testing
- Air-Q intubating laryngeal airway, Ambu-Aura intubating laryngeal mask
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain Management After Surgery, Regional Anaesthesia
We Have Two Groups. Both Groups Received a Deep Serratus Anterior Plane Block. One Group Had a Catheter for Continuous Infusion, While the Other Received IV Analgesics Postoperatively. Analgesic Effects Between the Two Groups Were Compared
The aim of this observational study is to compare the analgesic efficacy of continuous infusion via peripheral catheter versus single-shot serratus anterior plane block in women aged 18 to 80 undergoing breast-conserving surgery.
- Trial name
- DSAPB (NCT07053397)
- Testing
- Serratus Anterior Plane Block (SAPB) group, DSAPB
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medeniyet University
Pelvic Floor Disorders
Factors Influencing Hemodynamic Stability and Its Management in Patients Undergoing Pelvic Surgery Under Spinal and GA
Patients are at risk for hemodynamic instability both during and after surgery, as it is an independent predictor of long-term patient morbidity and length of hospital stay.
- Trial name
- NCT06767397
- Testing
- general anesthesia
- Where
- Pakistan
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Superior University
Supraglottic Airway Efficiency, Airway Complication of Anesthesia
Wei Nasal Jet Tube vs Gastro Laryngeal Tube in Endoscopic Retrograde Cholangiopancreatography
The most common adverse event in endoscopic procedures is hypoxia. Different airway devices have been investigated in the literature to prevent hypoxia.
- Conditions
- Supraglottic Airway Efficiency, Airway Complication of Anesthesia, Airway Aspiration, Complication of Anesthesia
- Trial name
- NCT05360810
- Testing
- Wei Nasal Jet Tube, Gastro Laryngeal Tube
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Bezmialem Vakif University
Cardiovascular Surgical Procedures, Pain, Postoperative
Fascial Plane Blocks and Quality of Recovery in Cardiac Surgery
In this randomized trial, the investigators will test the hypothesis that combining regional analgesia techniques-which have the potential to improve the quality of postoperative recovery following median sternotomy-with PIFB…
- Conditions
- Cardiovascular Surgical Procedures, Pain, Postoperative, Cardiovascular Diseases
- Trial name
- NCT07557108
- Testing
- Ultrasound-Guided Pectointercostal Fascial Plane Block, Ultrasound-Guided Rectus Sheath Block, Ultrasound-Guided Recto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Ordu University
Neuromuscular Blockade, Delayed Emergence From Anesthesia
Sugammadex Timing and Recovery Profile in Pediatric Adenotonsillectomy
Sugammadex is routinely used to reverse rocuronium-induced neuromuscular blockade in children. In clinical practice, it is given either while the child is still deeply anesthetized or after the anesthetic has lightened.
- Conditions
- Neuromuscular Blockade, Delayed Emergence From Anesthesia, Emergence Agitation
- Trial name
- SUGA-PED (NCT07902193)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Namik Kemal University
Anesthesia
Ultrasound-guided Interscalene Brachial Plexus Block: Single Bolus vs Continuous Catheter Placement in Arthroscopic Rotator Cuff Repair
Shoulder arthroscopy is a minimally invasive procedure frequently used for rotator cuff repair. Patients may experience severe postoperative (PO) pain, that can last for a month and can influence successful rehabilitation.
- Trial name
- ISB (NCT06855381)
- Testing
- the ISBC group, SonoPlex needle and E-catheter, single bolus injection
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Foggia
Spinal Anesthesia-Induced Hypotension, Cerebral Oxygenation
Effects of Ondansetron Timing During Spinal Anesthesia for Urologic Surgery
This study will evaluate whether the timing of intravenous ondansetron administration affects cerebral oxygenation and hemodynamic stability in older adults undergoing endoscopic urologic surgery under spinal anesthesia.
- Trial name
- NCT07858149
- Testing
- Ondansetron 8 mg, 0.9 % sodium chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Istanbul University
Postoperative Pain
Comparison of Paravertebral Versus Epidural Block for Post-thoracotomy Pain Control
This is a randomized, assessor-blinded, non-inferiority clinical trial comparing continuous thoracic paravertebral block (BPV) versus continuous thoracic epidural block (BPD) for postoperative pain control in adult patients…
- Trial name
- NCT07763249
- Testing
- Continuous Thoracic Paravertebral Block, Continuous Thoracic Epidural Block
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Post-operative Delirium, Cognitive Dysfunction
Effect of Epidural Analgesia on Burst Suppression
It has been shown in previous studies that burst suppression has an effect on the development of postoperative delirium (POD) and postoperative cognitive dysfunction (POCD).
- Conditions
- Post-operative Delirium, Cognitive Dysfunction, Electroencephalography
- Trial name
- NCT05688449
- Testing
- Bupivacaine-fentanyl, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Bezmialem Vakif University
Anesthesia, General
Impact of Flumazenil on the Emergence Delirium
Flumazenil rapidly antagonizes benzodiazepines (BZDs); it may induce agitation, seizure, or delirium, especially when applied to patients who have taken BZDs for a long time.
- Trial name
- NCT05681377
- Testing
- Flumazenil
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Korea University Guro Hospital
Blood Pressure, Intraoperative Hypotension
Perioperative Personalized Blood Pressure Management: IMPROVE-multi
Rates of major complications and mortality in the first weeks after surgery remain very high: postoperative mortality is still around 2% in central Europe and the United States.
- Conditions
- Blood Pressure, Intraoperative Hypotension, Postoperative Complications, Surgery
- Trial name
- IMPROVE (NCT05416944)
- Testing
- Personalized blood pressure management
- Where
- Germany
- Volunteers
- 1,272 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf