Clinical trials: Anesthesia Management
Anterior Cruciate Ligament Injuries, Anesthesia Injection Site
Ropivacaine and Midazolam by Intraarticular vs Epidural Administration in Arthroscopic ACL
Compare of the effectiveness of the use of ropivacaine and midazolam by intraarticular vs epidural administration on post-operative analgesia after isolated arthroscopic anterior cruciate ligament (ACL) reconstruction with…
- Conditions
- Anterior Cruciate Ligament Injuries, Anesthesia Injection Site, Knee Injuries
- Trial name
- NCT05078372
- Testing
- ropivacaine and midazolam intraarticular administration, ropivacaine and midazolam epidural administration
- Where
- Mexico
- Volunteers
- 108 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Videolaryngoscopy, Intubation Difficulty Scale
Comparison of VIDIAC, PeDiAC and Intubation Difficulty Scale in Pediatric Patients Undergoing Videolaryngoscopic Intubation
This prospective observational study aims to evaluate three scoring systems (VIDIAC (Video Laryngoscopic Intubation and Difficult Airway Classification), PeDiAC (Pediatric Difficult Airway Classification), and the Intubation…
- Conditions
- Videolaryngoscopy, Intubation Difficulty Scale, Vidiac Score, Difficult Airway Intubation
- Trial name
- VIDIPEDIDS (NCT07245511)
- Where
- Turkey (Türkiye)
- Volunteers
- 416 people
- Sponsor
- Ankara City Hospital Bilkent
Anesthesia
Ketamine and Propofol for Upper Endoscopy
The purpose of this study is to examine the dose-response relationship of ketamine in combination with propofol.
- Trial name
- NCT02295553
- Testing
- Ketamine, Propofol
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- The Hospital for Sick Children
Anesthesia General, Ultrasonography
Comparison of Two Airway Devices (I-Gel and Air-Q) in Children Aged 1-10 Years During General Anesthesia
This study aims to compare two commonly used airway devices (I-gel and Air-Q) in children aged 1-10 years undergoing general anesthesia for surgery.
- Conditions
- Anesthesia General, Ultrasonography, Laryngeal Mask Airways, Airway Management
- Trial name
- NCT07522957
- Testing
- I-gel supraglottic airway device, Air-Q SP supraglottic airway device
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Inguinal Hernia, Urinary Retention
Prophylactic Administration of Alpha Blockers for Prevention of Urinary Retention in Males Undergoing Inguinal Hernia Repair Under Spinal Anaesthesia.
Open inguinal hernia repair is one of the most common surgical procedures. Despite the fact that different of anesthetic procedures are proposed as alternatives to spinal anesthesia, the combination of spinal anesthesia with open…
- Trial name
- NCT03976934
- Testing
- Tamsulosin
- Where
- 2 sites in Greece
- Volunteers
- 100 people
- Sponsor
- Georgios Koukoulis
Pain, Inguinal Hernia
Comparison of Two Different Pain Management Techniques in Pediatric Patients Undergoing a Hernia Repair
The purpose of this research study is to find the best way to decrease pain in children right after surgery whom have had their hernia fixed.
- Trial name
- NCT01740193
- Testing
- TAP Block, Ilioinguinal/iliohypogastric blockade
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Surgery
Medical Management Survey : Organization of Perioperative Practices in Anesthesia and Ambulatory Surgery
In France, there are no precise data regarding perioperative organization of medical structure and care management of ambulatory surgical patients.
- Trial name
- OPERA (NCT02380430)
- Testing
- ambulatory surgery description
- Where
- 233 sites in France
- Volunteers
- 2,174 people
- Sponsor
- University Hospital, Grenoble
Anesthesia, Spinal, Spinal Puncture Complications
Ultrasound-assisted or Landmark-based Intrathecal Administration of Nusinersen in Adult Patients With Spinal Muscular Atrophy (The EchoSpin Study)
Nusinersen (Spinraza, Biogen Inc, Boston, MA), the first treatment approved by FDA and EMA for all Spinal Muscular Atrophy (SMA) subtypes, is an antisense oligonucleotide that is administered intrathecally through a lumbar…
- Conditions
- Anesthesia, Spinal, Spinal Puncture Complications, Spinal Muscular Atrophy, Ultrasonography
- Trial name
- EchoSpin (NCT05644899)
- Testing
- Interlaminar ultrasound-assisted intrathecal administration of nusinersen, Landmark-based intrathecal administration of nusinersen
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Chronic Postoperative Pain, Open Heart Surgery
Comparison of IV Analgesia, Thoracic Epidural Analgesia, and ESP Block for Chronic Pain After Open Heart Surgery
This prospective observational study aims to compare three routinely used postoperative analgesia techniques in patients undergoing open heart surgery: intravenous analgesia, thoracic epidural analgesia (TEA), and bilateral…
- Conditions
- Chronic Postoperative Pain, Open Heart Surgery, Postoperative Analgesia, Analgesia
- Trial name
- TEA-ESPB-IV (NCT07257744)
- Testing
- Intravenous Analgesia, Thoracic Epidural Analgesia (TEA), Erector Spinae Plane Block (ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Karadeniz Technical University
Hip Osteoarthritis, Hip Arthropathy
PENG Block for Total Hip Arthroplasty
This randomized, double-blinded, placebo-controlled trial seeks to evaluate the efficacy of the pericapsular nerve group block on postoperative rehabilitation.
- Conditions
- Hip Osteoarthritis, Hip Arthropathy, Hip Disease, Hip Pain Chronic
- Trial name
- NCT05944380
- Testing
- Ropivacaine 0.5% Injectable Solution, 0,9% normal saline
- Where
- Poland
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Postoperative Delirium, Delirium Prevention
Evaluation of a Hospital Program to Prevent Postoperative Delirium in Older Patients
Postoperative delirium is a common complication in older adults undergoing surgery. It is characterized by an acute and fluctuating disturbance of attention, awareness, and thinking.
- Conditions
- Postoperative Delirium, Delirium Prevention, Multicomponent Care Program, Older Adults (60 - 85 Years Old)
- Trial name
- EvaDel (NCT07787832)
- Testing
- Multicomponent delirium prevention program
- Volunteers
- 720 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Anesthesia, Surgery
Optimized Strict Fluid Management Helps Improve Endpoints After Liver Dissection
During hepatectomy, surgeons often prefer to restrict fluid intake, believing that this can lower central venous pressure (CVP) and reduce intraoperative blood loss.
- Trial name
- SHIELD-pilot (NCT07440121)
- Testing
- restrictive fluid infusion, preload, nitro
- Volunteers
- 90 people
- Sponsor
- Zhihong LU
Pain, Postoperative
Cesarean Delivery and Post-operative Pain Management With Local Anesthesia
The use of .5% Bupivacaine with epinephrine at the time of skin closure in cesarean deliveries will decrease post-op pain.
- Trial name
- NCT00298571
- Testing
- .5% bupivacaine with epinephrine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of South Florida
General Anesthetic Drug Overdose, Adverse Effect of Intravenous Anesthetics, Sequela
Fully Automated Anesthesia, Analgesia and Fluid Management
Evaluate the feasibility and quality of automated anesthesia, analgesia and fluid management based on a combination of several physiological variables (bispectral index [BIS], stroke volume [SV], and stroke volume variation…
- Conditions
- General Anesthetic Drug Overdose, Adverse Effect of Intravenous Anesthetics, Sequela, Complication of Anesthesia, Drug Delivery System Malfunction
- Trial name
- NCT02886806
- Testing
- BIS XP, Covidien, Ireland, EV-1000 TM, Edwards Lifesciences, Irvine, California, USA
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- Erasme University Hospital
Hypoxia, Airway Obstruction, Postoperative
Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia
The goal of this study is to determine whether omitting tracheal suctioning immediately prior to extubation is non-inferior to routine tracheal suctioning with respect to early postoperative oxygenation among adult surgical…
- Conditions
- Hypoxia, Airway Obstruction, Postoperative, Sore Throat, Cough, Postoperative
- Trial name
- NCT07287293
- Testing
- Routine Endotracheal Suctioning, Omission of Endotracheal Suctioning
- Where
- Thailand
- Volunteers
- 408 people
- Sponsor
- Mahidol University
Prostate Cancer, Pain Management
Efficacy Of Acupuncture in Pain and Anxiety During Transperineal Prostate Biopsy: A Prospective, Randomized, Sham-Controlled Trial
This randomized controlled trial evaluates the efficacy of acupuncture in reducing pain and improving patient experience during transperineal prostate biopsy.
- Conditions
- Prostate Cancer, Pain Management, Acupuncture Analgesia, Prostate Biopsy
- Trial name
- NCT06987071
- Testing
- Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Medipol University
BIS
The Influence Factors of Bispectral Index Values Increment Caused by Sugammadex
Sugammadex administration may increase the bispectral index (BIS) values during general anesthesia. The purpose of this study was to investigate the influence factors leading to increase in BIS value caused by sugammadex…
- Trial name
- NCT06561633
- Testing
- Sugammadex administration
- Where
- China
- Volunteers
- 135 people
- Sponsor
- Jun Zhang
Anesthesia, Peroperative Complication
Respiratory Management of Children Under Anaesthesia
Ventilation management in paediatric anaesthesia remains difficult because of the wide range of age and weight, and therefore practices are heterogeneous.
- Trial name
- PEDIAVENT (NCT04020900)
- Testing
- Respiratory management
- Where
- France
- Volunteers
- 701 people
- Sponsor
- Hospices Civils de Lyon
Iron Deficiency Anemia of Pregnancy, Iron-deficiency
Non-invasive Detection of Iron Deficiency in Obstetrics
Validation of non-invasive measurement of zinc protoporphyrin for detection of iron deficiency in pregnancy. In addition, the impact of iron deficiency on the incidence of postpartum depression, restless legs syndrome, obstetric…
- Conditions
- Iron Deficiency Anemia of Pregnancy, Iron-deficiency, Restless Leg Syndrome in Pregnancy, Restless Leg Syndrome Due to Iron Deficiency Anaemia
- Trial name
- PICCOLINO (NCT07083492)
- Testing
- non-invasive measurement of zink protoporphyrin
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Anaesthesia
First Administration to Man Of Org 25435 a New Intravenous Anesthetic
Title: First administration to man of Org 25435, a new intravenous anaesthetic. Protocol: 12.4.104 Clinical Phase: Phase I Study Site: Phase I Clinical Trials Unit Ltd Old Convent of Notre Dame 119 Looseleigh Lane Plymouth PL6…
- Trial name
- NCT01062867
- Testing
- ORG25435
- Where
- 2 sites in United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Plymouth