Clinical trials: Anesthesia Management
Colon Cancer, Rectal Cancer
Trial Comparing Transversus Abdominis Plane Block Versus Epidural Anesthesia for Pain Management in Colorectal Surgery
The primary outcome for this study is the Numeric Pain Score (NPS) for elective patients undergoing elective colorectal surgery that have been randomized to transversus abdominis plane block or epidural anesthesia for the…
- Conditions
- Colon Cancer, Rectal Cancer, Colonic Diverticulosis
- Trial name
- TAP (NCT02591407)
- Testing
- TAP Block, Continuous Epidural Analgesia
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Trinity Health Michigan
Shoulder Pain
Determining the Minimal Effective Volume (MEAV95) for Interscalene Brachial Plexus Block for Surgical Anesthesia
Interscalene block (ISB) consistently demonstrates superior pain relief after shoulder surgery. However, patients can experience complications such as blurred vision, hoarseness and shortness of breath with the standard volumes…
- Trial name
- MEAV 95 (NCT01703130)
- Testing
- Dose of of ropivacaine 0.75% used in block procedure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Airway Management in Elderly Patients Using Supra Glottic Airway Under General Anesthesia
Comparison of I-gel and I-gel Plus in Elderly Patients
This study compares the airway sealing pressure between I-gel® and I-gel plus® in elderly patients (aged 65-85) undergoing general anesthesia.
- Trial name
- NCT07125677
- Testing
- I-gel first, I-gel plus first, common
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Dongguk University International Hospital
Cesarean Section Complications, Spinal Anesthesia
Three Protocols for Phenylephrine Administration in Cesarean Delivery
The investigators will compare variable infusion of phenylephrine (at a starting rate of 0.75 mcg/Kg/min) with fixed rate (0.75 mcg/Kg/min which will stop of reactive hypertension occurred) and single shot (1.5 mcg/Kg)…
- Trial name
- NCT03302039
- Testing
- Single shot phenylephrine, Fixed infusion phenylephrine., Variable infusion phenylephrine.
- Where
- Egypt
- Volunteers
- 217 people
- Sponsor
- Cairo University
Mask Ventilation, General Anesthesia
Prediction of Difficult Mask Ventilation Using 3D-Facescan and Machine Learning
The aim of this study is to prove feasibility and assess the diagnostic performance of a machine learning algorithm that relies on data from 3D-face scans with predefined motion-sequences and scenes (MASCAN algorithm), together…
- Trial name
- MASCAN (NCT05411406)
- Where
- Germany
- Volunteers
- 423 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Epidural Anesthesia, Ropivacaine Concentration
Effects of Epidurally Administered Ropivacaine Concentration on the Hemodynamic Parameters
In this trial, the investigators intend to examine whether the concentration of local anesthetics during epidural analgesia could be modulating factor for change of hemodynamics in patients undergoing major upper abdominal…
- Conditions
- Epidural Anesthesia, Ropivacaine Concentration, Hemodynamics
- Trial name
- PNU (NCT01559285)
- Testing
- 0.75% ropivacaine concentration, 0.375% ropivacaine concentration, 0.2% ropivacaine concentration
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Pusan National University Hospital
Liver Transplantation
Closed-loop Anesthesia, Using Bispectral Index as the Control Variable, During Liver Transplantation
To compare closed-loop anesthesia to manual administration of propofol and remifentanil during liver transplantation
- Trial name
- Drone-TH (NCT00477347)
- Testing
- Closed loop administration, Manual administration
- Where
- 2 sites in France
- Volunteers
- 5 people
- Sponsor
- Hopital Foch
Preeclampsia, Lung Edema
Artificial Intelligence in Lung Ultrasound for Preeclampsia
A total of eight quadrants of standard lung US examination was performed to all pregnant women with preeclampsia within the scope of the study by the same anesthesiologist, dividing each hemithorax into four regions through the…
- Trial name
- NCT05487014
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Gazi University
Analgesia, Pain, Postoperative
Comparison Between the Caudal Block and Other Methods of Postoperative Pain Relief in Children Undergoing Circumcision
Prospective, randomized, case-controlled trial study. Observation post-operatively: Aims: This study aimed to compare the effectiveness of the caudal block CB with other methods of postoperative pain release.
- Conditions
- Analgesia, Pain, Postoperative, Pain, Acute
- Trial name
- paincontrol (NCT06086106)
- Testing
- caudal block, Dorsal Penile Nerve Block DPNB, Systemic opioids
- Where
- Bahrain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Salmaniya Medical Complex
Non-small Cell Lung Cancer, Lung Function Decreased
Effects of Nonintubated Thoracoscopic Lobectomy on Lung Protection
A novel nonintubated thoracoscopic technique is promising to enhance recovery after thoracic surgery. However, the effects of nonintubated technique on specific organ protection in not clear yet.
- Conditions
- Non-small Cell Lung Cancer, Lung Function Decreased, Tracheal Intubation Morbidity
- Trial name
- NCT03471884
- Testing
- Nonintubated thoracoscopic lobectomy, Intubated thoracoscopic lobectomy
- Where
- Taiwan
- Volunteers
- 82 people
- Sponsor
- National Taiwan University Hospital
Postoperative Nausea and Vomiting
Safety of Preoperative Oral Administration of a High Caloric Drink With Protein
The purpose of the study is to determine whether the oral administration of a high caloric drink with protein decreases the postoperative nausea and vomiting in patients with dysgnathia.
- Trial name
- NCT00151099
- Testing
- high caloric drink with protein
- Where
- Germany
- Sponsor
- University Hospital Muenster
Pulpitis, Pain Management
Effects of Topical Anesthesia Approaches on Dental Pain During and After Restorative Management of Dental Caries
The purpose of the Research Study and Overview of Participation: This study will compare different approaches used to prevent pain when giving local anesthesia to numb the teeth while managing dental cavities and decay.
- Trial name
- NCT07379515
- Testing
- Photobiomodulation (PBM)-induced analgesia device using multi-wavelength LED, Medicated analgesia
- Volunteers
- 204 people
- Sponsor
- Dubai Health
Anesthesia, Local
Lidocaine Administration Using STAR Particles
This study is being done to answer the question: Do STAR particles (tiny pieces of ceramic with small spikes) help numbing gel (a gel that helps you feel less pain) work more quickly to provide local anesthesia or numbing in a…
- Trial name
- NCT06034340
- Testing
- LET Gel after STAR Particle Application (Right or Left Arm), LET Gel Application without STAR Particle Application (Contralateral Arm)
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Emory University
Long QT Syndrome
QT Measurement Techniques and Anesthesia Management
In studies, the effects of drugs used for anesthesia and analgesia on QT distance were evaluated in isolation. However, drugs are administered in combination with each other during anesthesia induction.
- Trial name
- NCT04706104
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Heart Diseases, Pregnancy
Anaesthetic Management of Women With Heart Disease For Labor and Delivery
Heart disease among pregnant women is increasing in incidence. The cardiovascular changes associated with pregnancy may be particularly hazardous for both mother and fetus in a subset of these patients.
- Trial name
- NCT00403871
- Where
- 2 sites in Canada
- Volunteers
- 700 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Laryngeal Mask Airways, Airway Management
Study Comparing Intubation Via Video Laryngeal Mask Airways (VLMAs) Versus Video Laryngoscopy
The goal of this clinical trial is to compare the overall performance and patient outcomes of two video-assisted laryngeal mask airways (VLMAs) devices called Safe and Comfortable (SaCo) VLM and SafeLM® (Safe VLM) versus video…
- Conditions
- Laryngeal Mask Airways, Airway Management, Supraglottic Airways, Video-assisted
- Trial name
- NCT06396234
- Testing
- Safe VLM and airway management, Endotracheal intubation using video laryngoscope, SaCo VLM and airway management
- Where
- United States
- Sponsor
- Montefiore Medical Center
Pain Management, Dexmedetomidine
Dexmedetomidine Different Doses as Adjuvant to Entropy-assisted General Anesthesia During Functional Endoscopy Sinus Surgery.
The aim of work to assess the effect of different doses of Dexmedetomidine when used as an adjuvant to entropy-guided general anesthesia on the intraoperative surgical field quality, inhaled anesthesia consumption and…
- Conditions
- Pain Management, Dexmedetomidine, Anesthesia
- Trial name
- NCT05226325
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Cairo University
Bronchoscopy
Xylometazoline During Nasal Flexible Bronchoscopy
Flexible bronchoscopy is a commonly performed procedure and is usually performed transnasally. The optimal topical anesthesia regimen for bronchoscopy is investigational.
- Trial name
- VAIN (NCT03424889)
- Testing
- Xylometazoline, Saline
- Where
- 2 sites in India
- Volunteers
- 148 people
- Sponsor
- All India Institute of Medical Sciences
Normothermia, Intraoperative Temperature
Intraoperative Warming: Comparison of Two Temperature Management Systems
The goal of this clinical trial is to compare two temperature management systems, the warmUP (WU-20) and the Bair Hugger®, in preventing perioperative hypothermia during surgeries.
- Conditions
- Normothermia, Intraoperative Temperature, Anesthesia
- Trial name
- NCT06597214
- Testing
- AVACore Technologies, Inc. warmUP Sleeve, Arizant Healthcare Bair Hugger®
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Tampa General Hospital
Pain, Postoperative, Anesthesia, Local
Wound Infiltration as Part of an Opioid Free Pain Management Pathway Following Cesarean Delivery
This study will investigate the effect of three types of wound infiltration on post Cesarean opioid analgesia consumption when used in conjunction with an opioid free postoperative analgesia pathway.
- Conditions
- Pain, Postoperative, Anesthesia, Local, Opioid Use
- Trial name
- NCT03545516
- Testing
- Bupivacaine, Dexmedetomidine
- Where
- United States
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Richmond University Medical Center