Clinical trials: Anesthesia Outcomes
Anesthesia Outcomes, Anesthesia Complication
Does Style of Pre-sedation Instructions Improve Patient Outcomes in Ambulatory Anesthesia for Oral and Maxillofacial Surgery?
This randomized controlled trial aims to evaluate the impact of a brief guided visualization exercise on anesthesia-related outcomes in oral and maxillofacial surgery in patients scheduled for ambulatory anesthesia in the oral…
- Conditions
- Anesthesia Outcomes, Anesthesia Complication, Anesthesia and Procedure Related Time Intervals, Anesthesia Recovery Period
- Trial name
- NCT06768021
- Testing
- Guided visualization and standardized pre-sedation instructions, Standardized pre-sedation instructions only
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Alameda Health System
Analgesics, Opioid, Anesthesia, Spinal
Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief After Hip Replacement Surgery
Pain management after total hip replacement is one of the most important aspects of postoperative care for patients and clinicians alike.
- Conditions
- Analgesics, Opioid, Anesthesia, Spinal, Total Hip Replacement, Adverse Anesthesia Outcome
- Trial name
- NCT06878014
- Testing
- Spinal Anesthesia (bupivacaine), Postoperative pain management with acetaminophen, PCA IV Oxycodone
- Where
- 3 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Silesia
Emergence Delirium in Pediatric Anesthesia, Perioperative Ketonemia and Its Association With Recovery Outcomes in Children
"KETOMED: Ketonemia and Risk of Emergence Delirium in Children Undergoing General Anesthesia - A Multicenter Observational Study"
The objective of this observational study is to evaluate the relationship between ketonemia and emergence delirium in children undergoing general anesthesia.
- Trial name
- KETOMED (NCT07249736)
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital Clínico Universitario de Valladolid
Perioperative Respiratory Adverse Events, Anesthesia Outcomes
Nasal Decongestant to Reduce Perioperative Adverse Events in Children With Upper Respiratory Track Infections Having Anesthesia.
The goal of this multicentre, double-blind, randomised controlled trial study is to learn if the use of a nasal spray to open the nasal passages and increase airflow before surgery can reduce the occurrence of perioperative…
- Trial name
- NARWHAL (NCT07000877)
- Testing
- Decongestant nasal spray (oxymetazoline hydrochloride (0.05%))
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Telethon Kids Institute
Opioid Analgesia, Quality of Recovery (QoR-15)
Effect of Patient Preference for Intraoperative Opioid Use on Early Postoperative Quality of Recovery
Substituting the administration of opioids with a combination of alternative analgesics, known as opioid-free anesthesia (OFA), is gaining in popularity today and is typically administered as part of a larger multimodal strategy.
- Conditions
- Opioid Analgesia, Quality of Recovery (QoR-15), Outcome Assessment, Opioid Free Anesthesia
- Trial name
- PERFECT (NCT06855641)
- Testing
- Opioid based Anesthesia, opioid free anesthesia
- Where
- 2 sites in United States
- Volunteers
- 240 people
- Sponsor
- University of California, Los Angeles
Surgery, Anesthesia
Russian Registry of Surgical OutcomeS
Identification of risk factors that cause a high probability of an unfavorable outcome in the postoperative period is an urgent problem.
- Conditions
- Surgery, Anesthesia, Outcome, Fatal, Complication
- Trial name
- RuSOS (NCT06146270)
- Where
- 16 sites in Russia
- Volunteers
- 162,000 people
- Sponsor
- Russian Federation of Anesthesiologists and Reanimatologists
Patient Reported Outcome Measures, Quality of Recovery
Translation and Validation of the Turkish Version of the ObsQoR-11 Questionnaire
Ciechanowicz et al. developed and validated a postpartum recovery score for women with a caesarean section: the ObsQoR-11. The psychometric validation of the ObsQoR-11 confirms its reliability, its response to change, its…
- Conditions
- Patient Reported Outcome Measures, Quality of Recovery, Cesarean Section, General Anesthesia
- Trial name
- ObsQoR-11T (NCT04744311)
- Testing
- ObsQoR-11T Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Anesthesia, Brain Tumor, Supratentorial,Outcome
Study of the Depth of Anesthesia on Postoperative Clinical Outcome in Patients With Supratentorial Tumor
Recent studies have shown that deep anesthesia is associated with poor outcome. There is still lack of randomized controlled trials with large sample size on the effect of depth of anesthesia on the postoperative outcomes in…
- Trial name
- DEPTH (NCT03033693)
- Testing
- Bispectral index will be targeted at 50, Bispectral index will be targeted at 35
- Where
- China
- Volunteers
- 1,461 people
- Sponsor
- Beijing Tiantan Hospital
Quality of Recovery, Perioperative Complication
Validation of the QoR-15 Score for Emergency Surgery
Recovery from surgery is a complex process, depending on the characteristics of the patient, the anesthesia used, and the time required for surgical management.
- Conditions
- Quality of Recovery, Perioperative Complication, Anesthesia, Patient Reported Outcome Measures
- Trial name
- FQoR-15U (NCT04845763)
- Testing
- FQoR-15 questionnaire
- Volunteers
- 375 people
- Sponsor
- University Hospital, Angers
Anesthesia, Outcome, High-grade Glioma
The Impact of Anesthesia on High- Grade Glioma Patients
Although bench data and retrospective studies have provided a promising picture of the possible influence of anesthetic technique on the risk of tumor progression and patients mortality, current evidence from RCTs is inadequate…
- Trial name
- NCT02756312
- Testing
- IV Anesthesia, IH anesthesia
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Beijing Tiantan Hospital
Elderly, Malignant Tumor
Epidural Anesthesia-analgesia and Long-term Outcome
Surgical resection is one of the most important treatments for resectable cancer; on the other hand, cancer recurrence and/or metastasis are the major reasons of treatment failure.
- Conditions
- Elderly, Malignant Tumor, Surgical Resection, Epidural Anesthesia
- Trial name
- NCT03012945
- Testing
- Combined epidural-general anesthesia, General anesthesia
- Where
- 5 sites in China
- Volunteers
- 1,802 people
- Sponsor
- Peking University First Hospital
Elderly Patients, Solid Organ Cancer
Epidural Anesthesia and Long-term Outcomes in Elderly Patients After Surgery
Surgical resection is one of the most important treatments for solid organ cancer. Whereas cancer recurrence and/or metastasis are the major reasons of treatment failure.
- Conditions
- Elderly Patients, Solid Organ Cancer, Surgical Resection, Epidural Anesthesia
- Trial name
- NCT03335826
- Testing
- Combined epidural-general anesthesia, General anesthesia
- Where
- 5 sites in China
- Volunteers
- 1,802 people
- Sponsor
- Peking University First Hospital
Adverse Anesthesia Outcome
Prospective Comparison of Oral Intubation Via - Ambu® Aura Gain™ vs Slotted Guedel Tubus
The study has to show that an intubation with the AuraGain Laryngeal mask could bring the same benefits in terms of intubation in clinical practice, as the slotted Guedel tubus.
- Trial name
- NCT02570269
- Testing
- AuraGain, Slotted Guedeltubus
- Where
- Switzerland
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Nephrostomy; Complications, Upper Urinary Tract Dilatation and Obstruction
Quadratus Lumborum Block for Percutaneous Nephrostomy
Percutaneous nephrostomy (PCN) is one of the interventions in the radiology department in which pain control is necessary. Quadratus Lumborum (QL) block will be tried to limit the use of systemic analgesics and its accompanying…
- Conditions
- Nephrostomy; Complications, Upper Urinary Tract Dilatation and Obstruction, Regional Anesthesia Morbidity, Adverse Anesthesia Outcome
- Trial name
- QLB (NCT02121951)
- Testing
- Local Anesthetic infiltration, Quadratus Lumborum block, MAC
- Where
- Egypt
- Sponsor
- National Cancer Institute, Egypt
Adverse Anesthesia Outcome
Phenylephrine and Noradrenaline for Post Spinal Anesthesia Hypotension
Hypotension following spinal anesthesia for cesarean section is a serious problem. In this study we investigated the effect of the vasopressors phenylephrine and noradrenaline on postspinal hypotension.
- Trial name
- NCT03015857
- Testing
- phenylephrine, Norepinephrine, Bupivacaine
- Volunteers
- 200 people
- Sponsor
- Kasr El Aini Hospital
Adverse Anesthesia Outcome
A Comparison of Direct Laryngoscopy With Blind Intubation Via Intubating Laryngeal Tube Suction Disposable
Tracheal intubation is an important part of treatment for a trauma casualty. Tracheal intubation is usually achieved by a direct laryngoscope.It is an effective method but requires experience and skill demanding a long learning…
- Trial name
- NCT02884895
- Testing
- Intubating Laryngeal Tube Suction, Direct Laryngoscopy
- Volunteers
- 60 people
- Sponsor
- Bnai Zion Medical Center
Adverse Anesthesia Outcome
A Study Between the Laryngeal Tube Suction-Disposable and the Ambu AuraGain in Pediatric Patients
The study compared the Laryngeal Tube Suction Disposable (LTS-D) with the Disposable Laryngeal Mask Ambu® AuraGain™ (DLMA AG) during general anesthesia in pediatric patients.
- Trial name
- NCT02977559
- Testing
- Laryngeal Tube Suction Disposable, Laryngeal Mask Airway AuraGain
- Volunteers
- 60 people
- Sponsor
- Bnai Zion Medical Center
Adverse Anesthesia Outcome
The Effect of Preventive Use of Ondansetron in the Cesarean Section Under Spinal Anesthesia
Cesarean section is a frequent procedure in the obstetric surgery. The most widely used anesthesia technique for cesarean delivery is the spinal anesthesia The incidence of spinal anesthesia induced hypotension and bradycardia is…
- Trial name
- NCT02883192
- Testing
- Ondansetron
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Bnai Zion Medical Center
Adverse Anesthesia Outcome
The New Intubating Laryngeal Tube Suction-Disposable
The study compares the intubating Laryngeal Tube Suction (iLTS-D) with the Ambu®AuraGain™ in blind and fibreoptic endotracheal intubation.
- Trial name
- NCT02884843
- Testing
- Intubation laryngeal Tube Suction, AuraGain Laryngeal Mask
- Volunteers
- 60 people
- Sponsor
- Bnai Zion Medical Center
Adverse Anesthesia Outcome
Comparison of Direct Laryngoscopy With Blind Intubation Via Intubating Laryngeal Mask Airway
Control the airways by endotracheal intubation is an important part of treatment for a trauma casualty. The use of the Laryngeal Mask Airway for fast control of the airway is known for many years.
- Trial name
- NCT02884869
- Testing
- Intubating Laryngeal Mask
- Volunteers
- 60 people
- Sponsor
- Bnai Zion Medical Center