Clinical trials: Anesthesia Practice, open to volunteers
Communication Research, Patient Satisfaction
Breaking Bad News Skills of Doctors and Residents in the Surgical Setting
Breaking bad news is a very stressful and difficult situation for health care professionals, especially clinical doctors and surgeons.
- Conditions
- Communication Research, Patient Satisfaction, Communication Programs, Doctor Patient Relation
- Trial name
- NCT04308707
- Testing
- Breaking bad news skills
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Clinic of Barcelona
Mechanical Ventilation Complication, Pediatric ALL
Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia
Postoperative pulmonary complications (PPCs) are common in children undergoing general anesthesia and are associated with prolonged stay in the hospital and high costs.
- Conditions
- Mechanical Ventilation Complication, Pediatric ALL, Pulmonary Complication, Perioperative/Postoperative Complications
- Trial name
- BIG APPLE (NCT06166706)
- Where
- 4 sites in Australia, Italy and 2 more
- Volunteers
- 10,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Anesthesia
Effect of Sedative and Anxiolytic Premedication on Children Experience After General Anesthesia
Children undergoing general anesthesia for surgery commonly need sedative and anxiolytic premedication but little clinical evidence supports is benefit for children older than 7 years old.
- Trial name
- pediaPREM (NCT05681572)
- Testing
- Midazolam, Dexmedetomidine
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Montpellier
Anesthesia
VR in Undergraduate Anesthesia Training
Medical students learning anesthesia often face challenges in gaining hands-on experience due to the complexity of the operating room environment.
- Trial name
- NCT07079059
- Testing
- Virtual Reality Training
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cataract and IOL Surgery, Cataract Surgery Anesthesia
The Impact of Physiologic Cataract Surgery on Patient Comfort and Medication Usage
The study will pertain to investigating the impact of high vs low IOP on the intraoperative experience and comfort for the patient and surgeon.
- Conditions
- Cataract and IOL Surgery, Cataract Surgery Anesthesia, Cataract Surgery Experience, Nuclear Cataract
- Trial name
- NCT07223866
- Testing
- High IOP Setting, Low IOP Setting
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Matthew Rauen
Pediatric Anesthesia, Pediatric Surgery
Pediatric Anesthesia: The Childs Voice
In Denmark, around 25,000 children under 18 undergo general anesthesia annually. Hospital stays and anesthesia can induce significant anxiety and stress in children due to unfamiliar environments, procedures, and communication…
- Conditions
- Pediatric Anesthesia, Pediatric Surgery, PROMs, PREMs
- Trial name
- PHEASE (NCT07289152)
- Where
- 3 sites in Denmark
- Volunteers
- 250 people
- Sponsor
- Gødstrup Hospital
Labor Analgesia
Anesthesia Clinical Practice During Labour Neuraxial Analgesia
The goal of this observational study is to evaluate the communication between the anesthesiologist and the patient prior the initiation and during the administration of the labor neuraxial analgesia.
- Trial name
- ACP-LNA (NCT07083167)
- Testing
- No Interventions.
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Mechanical Ventilation, Extubation
Clinical Practices of Extubation After Invasive Mechanical Ventilation
Extubation is a delicate and complex phase of airway management in anesthesia and critical care. A variety of complications are of concern, ranging from transient hypoxemia to the need for reintubation, which can then become…
- Conditions
- Mechanical Ventilation, Extubation, Anesthesia, Critical Care, Intensive Care
- Trial name
- EPP/EPP = 1 (NCT07554586)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Decision Making , Cesarean Section
The Impact of a Shared Decision-Making Intervention on Intraoperative Patient Experience During Elective Cesarean Delivery Under Spinal Anesthesia
Caesarean delivery (CD) is a common surgical procedure performed when vaginal delivery poses risks to the mother or fetus, with global rates projected to reach 28.5% by 2030.
- Trial name
- NCT07476482
- Testing
- Proactive Plan: prophylactic IV ketamine 0.2 mg/kg or IV midazolam 1 mg given prior to incision. Reactive Plan: no prophylactic medication; rescue IV fentanyl 50 mcg administered only if NRS ≥4., Control Group (Standard Care)
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Anxiety, Anxiety After Surgery
The Study Evaluates the Effect of an Interactive Projector as a Distraction for Children During Anesthetic Induction. The Primary Objective is to Reduce Perioperative Anxiety, Measured With the Modified Yale Preoperative Anxiety Scale (mYPAS).
This study is designed to evaluate the effect of technology as a distraction technique during anesthetic induction in children, starting from their arrival to the operating room.
- Conditions
- Anxiety, Anxiety After Surgery, Induction of Anesthesia, Anxiety Preoperative
- Trial name
- NCT07230743
- Testing
- Custom projector-based video game intervention (BERT; Stanford Chariot Program, Palo Alto, CA), Standard Parent-Present Induction (PPI)
- Where
- Chile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Clinica Alemana de Santiago
Hand Injuries and Disorders
Wide-Awake Local Anesthesia No-Tourniquet (WALANT) Procedures
The goal of this clinical trial is to learn whether a standardized preoperative educational video improves expectation management and the patient experience in adults undergoing Wide-Awake Local Anesthesia No Tourniquet (WALANT)…
- Trial name
- WALANT (NCT07832591)
- Testing
- Preoperative WALANT Educational Video, Traditional Preoperative Counseling
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Carilion Clinic
Prostate Biopsy
Use of a Virtual Reality Headset During Prostate Biopsy Under Local Anesthesia to Improve the Patient's Experience
This is a post-market clinical investigation evaluating the effect of immersive virtual reality (VR) as an adjunct to standard local anesthesia during transperineal prostate biopsy.
- Trial name
- NCT07701421
- Testing
- Standard Local Anesthesia, Immersive Virtual Reality (VR) Headset
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS San Raffaele
Cardiac Anaesthesia, Cardiac Surgery
Anesthesia, Perfusion, and Surgical practicEs in Cardiac Surgery
Perioperative management in cardiac surgery, particularly the use of anesthesia, cardiopulmonary bypass (CPB), and surgical techniques, remains highly variable across institutions.
- Conditions
- Cardiac Anaesthesia, Cardiac Surgery, Perfusion, Anesthesia
- Trial name
- APECx (NCT07255924)
- Where
- Netherlands
- Volunteers
- 15,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Anesthesia, Sedation
The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes
Perioperative fasting has historically been viewed as a low-risk intervention. However, preliminary data indicate that perioperative loss of nutrition and fluids is likely harmful.
- Conditions
- Anesthesia, Sedation, Monitored Anesthesia Care, Procedure
- Trial name
- MACS (NCT07022951)
- Testing
- Preoperative fasting
- Where
- United States
- Volunteers
- 1,200,000 people
- Sponsor
- Massachusetts General Hospital
Anaesthesia Conduction, Paediatric and Adult Patients
Sustainable Anaesthesia Practices in EUROPE - a Prospective International Cohort Study
In response to the climate crises, Societies of Anaesthesiology around the globe call for action to reduce the carbon footprint of daily clinical work.
- Conditions
- Anaesthesia Conduction, Paediatric and Adult Patients, Carbon Footprint in Anesthetic
- Trial name
- SUSTAIN-EUROPE (NCT07252973)
- Testing
- Anaesthesia technique
- Volunteers
- 2,000 people
- Sponsor
- European Society of Anaesthesiology
Surgeries Undergoing General Anesthesia
Impact of Intraoperative Oxygenation Practices on Patient Outcomes
This multicenter, cluster-randomized, cluster-crossover clinical trial evaluates the impact of three intraoperative FiO2 (Fraction of Inspired Oxygen) oxygenation strategies-lower (FiO₂ 0.21-0.40), intermediate (FiO₂ 0.40-0.80)…
- Trial name
- IntraOp Ox (NCT07224243)
- Testing
- Lower FiO2, Intermediate FiO2, Higher FiO2
- Where
- 4 sites in United States
- Volunteers
- 54,000 people
- Sponsor
- Frederic T Billings IV
Discomfort, Psychological Well Being
Patient Experiences of Intraoperative Discomfort During Cesarean Delivery Under Neuraxial Anesthesia
During a cesarean delivery done under spinal or epidural anesthesia, many patients notice sensations they weren't expecting things like pressure, pulling, tugging, or nausea even though the anesthesia blocks pain.
- Trial name
- ICAT (NCT07867106)
- Testing
- Interview
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Nephrolithiasis
Postoperative Analgesia Practices After Percutaneous Nephrolithotomy
This prospective observational study aims to evaluate the effectiveness and safety of different postoperative analgesia methods used in patients undergoing percutaneous nephrolithotomy (PCNL).
- Trial name
- NCT07258901
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istinye University
Acute Pain, Chronic Post Operative Pain
Understanding the Acute Pain Phenotype in Patients Undergoing Surgery
The goal of this observational study is to learn about how regional anesthesia (numbing medication) affects pain in patients with different psychosocial phenotypes such as different levels of concern about pain, sleep issues, and…
- Conditions
- Acute Pain, Chronic Post Operative Pain, Opioid Use
- Trial name
- NCT06466941
- Testing
- regional anesthesia, no regional anesthesia, acute pain consultation
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Brigham and Women's Hospital
Rapide Sequence Induction, Tracheal Intubation
Pain Assessment During Rapid Sequence Induction
Rapid sequence induction (RSI) is a standard anesthesia technique used in patients at risk of aspiration. Although tracheal intubation following RSI is a frequent and painful procedure, no study has yet evaluated nociception…
- Conditions
- Rapide Sequence Induction, Tracheal Intubation, Nociception, General Anesthesia
- Trial name
- NARSI (NCT07588165)
- Testing
- No Intervention: Observational Cohort
- Where
- Monaco
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Princesse Grace