Clinical trials: Anesthesia Recovery
Anesthesia
Ultrasound-guided Serratus Plane Block for the Quality of Recovery After Modified Radical Mastectomy
Regional anesthesia improves quality of recovery after surgery in many studies. Ultrasound-guided serratus plane block is a novel technique which may be a viable alternative to current regional anesthetic techniques.
- Trial name
- NCT02691195
- Testing
- Ropivacaine, 0.9% Nacl
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Fujian Provincial Hospital
Anesthesia, ERAS
Impact of General Anesthesia v/s Spinal Anesthesia on ERAS Parameters in Intestinal Stoma Reversal
Randomized, Interventional ,Open labeled, Parallel Assignment and Superiority trial.
- Conditions
- Anesthesia, ERAS, Surgical Stomas, Ileostomy - Stoma
- Trial name
- SPIGERAS (NCT06226753)
- Testing
- Type of anaesthesia used
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Anesthesia
Quadratus Lumborum Versus Transversus Abdominis Plane Nerve Block: A Comparison Study
The Transversus Abdominis Plane (TAP) block is the current standard of care for patients undergoing laparoscopic abdominal surgeries with the Enhanced Recovery After Surgery (ERAS) Protocol.
- Trial name
- NCT03490357
- Testing
- Control - Transversus Abdominus Plane Block, Quadratus Lumborum Block
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Postoperative Complications
4-choice Reaction Time Test for the Measurement of Psychomotor Recovery After General Anaesthesia
The recovery of patients after general anaesthesia is usually estimated by using clinical signs and scores. Since there is a lack of the agreed objective methods for assessing cognitive and psychomotor recovery after general…
- Trial name
- 4CRT_Ane (NCT03697057)
- Testing
- General anaesthesia
- Where
- Germany
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Elderly Patients, Anesthesia
Effect of Dexmedetomidine on Recovery Profiles of Elderly Patients
Emergence of elderly patients from anesthesia may face with cognitive dysfunction or agitation such as delirium. There are reports that using dexmedetomidine as a adjuvant for general anesthesia decreased emergence-agitation in…
- Conditions
- Elderly Patients, Anesthesia, Emergence From Anesthesia, Effects of Dexmedetomidine
- Trial name
- CSUHAPM (NCT01851005)
- Testing
- Dexmedetomidine, Sevoflurane, Propofol and Remifentanil
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chosun University Hospital
Anterior Cervical Discectomy and Fusion (ACDF) Surgery
Comparison of Postoperative QoR-15 Scores Between Sevoflurane and Remimazolam
The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the cervical spine surgery.
- Trial name
- NCT05019222
- Testing
- Sevoflurane based inhalation anesthesia, Remimazolam based total intravenous anesthesia
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Clinical Decision Support System
Pre-anesthesia Imaging-based Respiratory Assessment and Analysis
This study is to establish a preoperative respiratory imaging assessment database and develop a difficult intubation risk prediction model and further risk analysis.
- Trial name
- NCT06270797
- Testing
- intubation for general anesthesia
- Where
- Taiwan
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Postoperative Delirium
EEG-Guided Analgesic Titration During General Anesthesia to Improve Early Neurocognitive Recovery in Older Patients
The investigators intend to recruit 600 participants to see if alpha power during anesthesia is influenced by analgesic medication and associated with a reduction of delirium following surgery.
- Trial name
- ALPHA-DEX (NCT04443517)
- Testing
- Alpha Optimization, Emergence from anesthesia with Dexmedetomidine
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Columbia University
Thyroid Cancer
Effect of Perioperative Intravenous Lidocaine Infusion and Magnesium Infusion on the Functional Recovery After General Anesthesia in the Patients Undergoing Thyroid Surgery
Studies have attempted to control pain and increase patients' recovery satisfaction following many kinds of operations by using as small an opioid analgesic dose as possible and adding a nonopioid analgesic to reduce the side…
- Trial name
- NCT02018276
- Testing
- Lidocaine, Magnesium
- Where
- South Korea
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Anesthesia, ERAS
Goal-Directed Fluid Therapy in Patients Undergoing Lower Limb Surgeries
Controlling the amount of fluids given to patients in perioperative setting can significantly influence their outcomes.
- Conditions
- Anesthesia, ERAS, Fluid Overload, Hypovolemia; Surgical Shock
- Trial name
- NCT06133257
- Testing
- Goal-Directed Fluid Therapy guided by Inferior Vena Cava Collapsibility Index, standard fluid management
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Pain, Postoperative, Pain, Acute
Opioid Sparing Anesthesia in Lumbar Spine Surgery
The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus remifentanil analgesia in lumbar…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Nociceptive
- Trial name
- NCT05594407
- Testing
- dexmedetomidine-ketamine-lidocaine, Remifentanil
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aretaieion University Hospital
General Anesthesia, Propofol Pharmacodynamics
Neuronal Inertia in Propofol Anesthesia
Loss and recovery of consciousness during propofol anesthesia seem to be mediated by different mechanisms beyond the actual effect-site concentration of anesthetic drug.
- Conditions
- General Anesthesia, Propofol Pharmacodynamics, Propofol Target Controlled Infusion, Loss of Consciousness and Recovery of Consciousness
- Trial name
- INERTIA (NCT01962285)
- Testing
- propofol targel controlled infusion
- Where
- Chile
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Quality of Recovery, Anesthesia
Improving ObsQoR-11 With Continuous Wound Infusion Versus Intrathecal Morphine After Elective Cesarean Delivery
The purpose of this prospective randomized double-blinded and controlled study is to evaluate the quality of recovery after elective cesarean delivery using the Obstetric Quality-of-Recovery-11 (ObsQoR-11) score at 24 hours…
- Conditions
- Quality of Recovery, Anesthesia, Postoperative Pain, Cesarean Section
- Trial name
- CIVIMEC (NCT05696678)
- Testing
- Intrathecal Morphine, Ropivacaine 0.2%
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Delirium
Clinical Investigation of an Eye-Tracking Device as a Predictor of Delirium in the Recovery Room After Surgery With General Anesthesia
Neurotrack™ is an FDA-approved device for measuring and tracking cognitive decline, as may occur with age-related cognitive decline and Alzheimer's disease.
- Trial name
- NCT05579093
- Testing
- Cognitive test + Pupillary measure
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Columbia University
Opioid Use, Pain, Postoperative
Outcome of Multimodal Anesthesia Bern
In the context of the ongoing opioid crisis in the USA and Europe, reducing perioperative opioid use is a growing priority. Multimodal anesthesia (MMA) offers a patient-centered alternative to opioid-free anesthesia, combining…
- Conditions
- Opioid Use, Pain, Postoperative, Postoperative Complications, Postoperative Nausea
- Trial name
- NCT06985069
- Testing
- General anesthesia applying multimodal anesthesia, General anesthesia using conventional opioid-based regimen
- Where
- Switzerland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Postoperative Recovery, Inhalation Anesthesia
Effect of Combined Intravenous-Inhalational Anesthesia (CIVIA) on Postoperative Recovery Patterns.
This study was planned as a single-center, prospective, randomized trial. Adult patients undergoing elective spinal surgery lasting longer than three hours, performed in a neurosurgery operating room, will be evaluated.
- Conditions
- Postoperative Recovery, Inhalation Anesthesia, Total Intravenous Anesthesia
- Trial name
- NCT07123870
- Testing
- Sevofluorane, Desflurane, Total Intravenous Anesthesia(TIVA)
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital