Clinical trials: Anesthesia Spinal
Pain, Postoperative
The Effect of IV Dexamethasone on the Duration of Analgesia of Spinal Anaesthesia for C-Sections at a Jamaican Hospital
Dexamethasone is one of many adjuncts tested to prolong the duration of spinal anesthesia and its analgesic effect. The intent of this, a single-site, double-blinded, randomized controlled trial, is to determine if a single…
- Trial name
- NCT04624360
- Testing
- Dexamethasone
- Where
- Jamaica
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Anesthesia, Spinal
Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgery
The following obstetric procedures are commonly performed with spinal anesthesia on labor and delivery: bilateral tubal ligation, external cephalic version, cerclage insertion, cerclage removal, minimally invasive fetal surgery…
- Trial name
- CLIMB (NCT03967288)
- Testing
- Chloroprocaine Injection [Clorotekal], Bupivacaine Hydrochloride 0.75% Injection Solution
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Operation
Spinal Anesthesia Magnesium Infusion
The aim of this study was to investigate the effect of i.v. infusion of magnesium sulphate during spinal anesthesia on duration of spinal block and postoperative pain.
- Trial name
- NCT02011152
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Gynecologic Laparoscopic Surgery
Intrathecal Mg in Gynecologic Laparoscopic Surgeries.
The investigators aim to investigate the differences between intrathecal Bupivacaine + Mg sulfate in spinal anesthesia versus Bupivacaine on surgeon satisfaction and postoperative pain in gynecologic laparoscopic surgeries.
- Trial name
- NCT02671227
- Testing
- intrathecal Mg sulfate., intrathecal bupivacaine 15 mg.
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Temperature Change, Body
Study to Evaluate the Accuracy of the New Monitor of Temperature in Comparison With the Consecrated Thermometers by Literature
This study compares the use of the "SPOT ON" thermometer with the oral, esophageal in participants submitted to general and the oral thermometer to spinal anesthesia, from the pre op, intra and post op stages, evaluating the…
- Trial name
- NCT03057886
- Testing
- Comparative thermometers to compare with a new device
- Where
- Brazil
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Ricardo Caio Gracco De Bernardis
Orthopedic Surgery-lower Leg Surgery
Efficacy of Peripheral Nerve Stimulator in Assessing Sensory Nerve Block Level of Spinal Anesthesia
Various methods are used to assess the level of anesthesia block after spinal anesthesia. Among them, ice cubes, alcohol swabs, and needles are commonly used in the clinical setting, but ice is limited by difficulties with…
- Trial name
- NCT01768780
- Testing
- the anticholinergic glycopyrrolate 0.1 ㎎ + 0-15 mg hyperbaric bupivacaine
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Spinal Anesthesia, Transurethral Resection of Prostate
Spinal Morphine Provides an Effective Pain Control in Patients Undergoing Transurethral Resection of Prostate Gland
Pain after transurethral resection of prostate is considered mild to moderate severity from detrusor muscle spasm and traction from urinary catheter.
- Conditions
- Spinal Anesthesia, Transurethral Resection of Prostate, Analgesia
- Trial name
- NCT02458742
- Testing
- Morphine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Caesarean Section, Spinal Anesthesia
Effect of Bilateral Quadratus Lumborum Block for Pain Relief in Patients With Cesarean Section
Cesarean section commonly induces moderate to severe pain for 48 hours. These patients have additional compelling reasons to provide adequate pain relief as early mobilization is a key factor to prevent the risk of thromboembolic…
- Conditions
- Caesarean Section, Spinal Anesthesia, Quadratus Lumborum Block, Analgesia
- Trial name
- NCT03199170
- Testing
- Intrathecal morphine, Bilateral Quadratus Lumborum Block, Intrathecal morphine with bilateral Quadratus Lumborum Block
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Anesthesia, Analgesia
Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural
As the dural puncture epidural (DPE) is increasing in popularity for labor analgesia, it is important to understand how it impacts outcomes in parturients.
- Trial name
- NCT05514431
- Testing
- Epidural, Dural Puncture Epidural (DPE) technique, Combined Spinal-Epidural (CSE) technique
- Where
- 2 sites in United States, Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Morbid Obesity
The Ultrasound Guided Versus Land-mark Location Method for Performing Spinal Anesthesia in Obese Parturients
This study will be investigated whether an ultrasound-assisted technique is better than a classical land-mark technique to facilitate spinal anesthesia in the lateral position in morbidly obese pregnant women with BMI ≥ 40 who…
- Trial name
- NCT05342922
- Testing
- Ultrasound group, Landmark group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Pain, Acute
Intrathecal Midazolam, Fentanyl and Nalbuphine as Adjuvants to Bupivacaine in Spinal Anesthesia for Cesarean Section
The main limitations of spinal anesthesia are its short duration of action and do not provide prolonged postoperative analgesia when it is performed only with local anesthetics.
- Trial name
- NCT04932083
- Testing
- Bupivacaine, Fentanyl, Nalbuphine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Benha University
Adverse Reaction to Spinal Anesthetic, Maternal Care for Cervical Incompetence
Chloroprocaine Spinal Anesthesia for Cervical Cerclage (CP Spinal)
This study aims to determine whether or not spinal anesthesia with the local anesthetic drug, chloroprocaine, wears off faster than the local anesthetic drug, bupivacaine, and results in faster discharge from the post-anesthesia…
- Trial name
- NCT02862912
- Testing
- Chloroprocaine, Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Columbia University
Anesthesia, Spinal, Cesarean Section
Post Spinal Anesthesia Hypotension and Preoperative Hydration
Study of the impact of preoperative oral rehydration on the incidence of spinal anesthesia-induced hypotension for scheduled cesarean section.
- Trial name
- NCT04450667
- Testing
- Nutricia PreOp
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Postoperative Pain, Complications
A Trial of Closed Hemorrhoidectomy Under Local Perianal Block Versus Spinal Anesthesia
Hemorrhoidectomy can be carried out under several modes of anesthesia. In western country hemorrhoidectomy usually be performed under general anesthesia, however there may be the complications resulted from general anesthesia…
- Conditions
- Postoperative Pain, Complications, Satisfaction
- Trial name
- NCT00925912
- Testing
- spinal block, Perianal block
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Cesarean Section, Spinal Anesthesia
Predictability of ANI (Analgesia Nociception Index) for Spinal Hypotension
Spinal anesthesia is widely accepted as the anesthetic method of choice for Cesarean section. However, the incidence of spinal hypotension is 50-70%, and the decrease in blood pressure is often rapid and severe.
- Trial name
- NCT06327165
- Testing
- observation
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Postoperative Pain After Total Knee Arthroplasty, Postoperative Pain
Postoperative Pain and Analgesic Use After Total Knee Arthroplasty
This prospective observational study evaluates postoperative pain intensity and analgesic consumption in patients undergoing total knee arthroplasty (TKA) under different anesthesia techniques.
- Conditions
- Postoperative Pain After Total Knee Arthroplasty, Postoperative Pain, Analgesic Consumption
- Trial name
- NCT07457814
- Where
- Czechia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tomas Bata Hospital, Czech Republic
Anesthesia, Spinal, Nonemergency Cesarean Section
Spinal Anaesthesia for Caesarean Section: Descriptive Multicentre Study
Most of caesarean sections can be performed under spinal anaesthesia. Its major advantages are reliability and fast onset. However, dose of hyperbaric bupivacaine used, combination with adjuvants, hemodynamic management, and…
- Trial name
- CesAR (NCT04719819)
- Testing
- Spinal anaesthesia for caesarean section
- Where
- 11 sites in France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Inguinal Hernia
Inflammatory Response: General vs Spinal Anesthesia
Objective: This study aimed to compare the effects of general and spinal anesthesia on the inflammatory response by measuring intercellular adhesion molecule-1 (ICAM-1), P-selectin (SELP), and thrombomodulin (TM) levels in…
- Trial name
- NCT07567534
- Testing
- inflammatory response during inguinal hernia repair.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sezen Kumaş Solak
Healthy Participants
Rate of Tranexamic Acid Administration on Blood Pressure (RateTXA) Study.
Tranexamic acid is a well-established treatment for post-partum hemorrhage. This study aims to examine the effect of tranexamic acid administration rates on blood pressure changes over 1 minute compared to 10 minutes in healthy…
- Trial name
- RateTXA (NCT06356948)
- Testing
- Tranexamic Acid (TXA)
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Aortocaval Compression, Fetal Acidosis
Neonatal Acid-Base Status After C Section With Maternal Tilt vs. Supine
This study aims to compare the neonatal acid-base status of women who remain supine horizontal, with women who are tilted to the left side by 15° during elective cesarean delivery at term under spinal anesthesia, with systolic BP…
- Trial name
- NCT02243423
- Testing
- SUPINE, TILT
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University