Clinical trials: Anesthesia Time
Comparison of Buffered Versus Non Buffered Local Anesthetic In Inflamed Tissues
"Comparison of Buffered Versus Non-Buffered Local Anesthetic in Patients With Inflamed Tissues for Pain Perception, Onset, Duration and Adverse Effects"
This study aims to determine whether buffered or non-buffered local anesthetic (LA) is more effective and safer for managing pain in patients with inflamed tissues undergoing surgical procedures.
- Trial name
- NCT07592143
- Testing
- Buffered Local Anesthesia
- Volunteers
- 68 people
- Sponsor
- King Edward Medical University
Sugammadex, Extubation
Effectiveness on Smooth Extubation According to the Administration Time of Sugammadex
After surgery is completed under general anesthesia, extubation is performed after recovery from anesthesia, and during this process, bucking, coughing, and rapid and excessive hemodynamic fluctuations occur very often.
- Conditions
- Sugammadex, Extubation, Smooth Emergence
- Trial name
- NCT05751603
- Testing
- sugammadex
- Volunteers
- 66 people
- Sponsor
- Ajou University School of Medicine
Laparoscopic Cholecystectomy
Low-Dose Ketamine Infusion for Post-Operative Pain in Patients Undergoing Laparoscopic Cholecyctectomy
Following surgery, acute pain is a typical issue with a variety of implications. Surgeons, anesthesia specialists, and patients all desire effective pain management with the fewest possible adverse effects.
- Trial name
- NCT06966596
- Testing
- Ketamine only
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Fazaia Ruth Pfau Medical College
Remimazolam, Body Composition
Body Composition Analysis and Time to Emergence From Remimazolam
Remimazolam is a novel general anesthetic drug. The time to emergence from remimazolam-based general anesthesia is variable among patients, but little is known about the risk factors for delayed emergence.
- Trial name
- NCT05512559
- Testing
- body composition analysis
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Samsung Medical Center
Electroconvulsive Therapy, Anesthesia, General
Induction Agents in ECT: Effects on Seizure Duration, Quality, and Recovery
The goal of this observational study is to determine if there are any differences in seizure duration, seizure quality, and recovery time associated with the utilize of different anesthetic induction agents in patients undergoing…
- Trial name
- NCT07596095
- Testing
- Propofol group, Thiopental, Ketamine (0.5 mg/kg)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Hemodynamic
Use of the Aortic Time-velocity Integral Via Suprasternal Ultrasound to Search Preload Dependence in Paediatric Surgery : Kid's Fluid Management (FM)
After major surgery, fluid overload is associated with an increase of morbidity and mortality. Fluid administration should therefore be given wisely.
- Trial name
- Kid's FM (NCT07099664)
- Testing
- Measurement of aortic Vmax and VTI with suprasternal doppler.
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Lille
Hypotensive Anesthesia, Orthognathic Surgery
Hypotensive Anesthesia for Orthognathic Surgery
The overall objective of this double blinded, randomized controlled trial (RCT) is to compare specific outcomes of three medications (Dexmedetomidine, Nicardipine, and Labetalol) which are routinely used to lower blood pressure…
- Trial name
- NCT06093893
- Testing
- Dexmedetomidine, Nicardipine, Labetalol
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Boston Medical Center
Depth of Anaesthesia
Quantifying Nitrous Oxide Effect on Depth of Anaesthesia Using Theoretically Based Time Series Modelling
Our hypothesis is that a new method of depth of anaesthesia monitoring, using theoretically based time series modelling will result in improved ability to determine nitrous oxide anaesthetic effect
- Trial name
- NCT00226837
- Testing
- Nitrous oxide
- Where
- 2 sites in Australia
- Volunteers
- 60 people
- Sponsor
- Melbourne Health
Emergence From Anesthesia, EEG Power Spectra
Anesthetic Sensitivity Assessed by Alpha Band Power and Its Association With Emergence Time From Sevoflurane General Anesthesia in Young Adults.
The goal of this observational study is to determine the relationship between brain activity patterns and recovery time in adult patients (ages 35-50, ASA I-II) undergoing elective general anesthesia.
- Trial name
- ALPHA-SET (NCT07254975)
- Testing
- Intraoperative EEG Recording
- Where
- Chile
- Volunteers
- 70 people
- Sponsor
- University of Chile
Pain, Postoperative
Intrathecal Paracetamol Before Spinal Anaesthesia With Chloroprocaine HCl 1% for Short Knee Procedures
This is a phase II, single centre, randomised, parallel-group, double-blind, three doses, placebo-controlled, exploratory efficacy and safety study.
- Trial name
- NCT03428230
- Testing
- 30 mg Paracetamol 3% (1 mL), 60 mg Paracetamol 3% (2 mL), 90 mg Paracetamol 3% (3 mL)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Sintetica SA
Hypotension, Obstetric Anesthesia Problems
Prevention of Maternal Hypotension During Cesarean Section With Norepinephrine Infusion.
This will be a randomized study aiming at investigating the combination of a norepinephrine infusion and colloid preloading versus the combination of a norepinephrine infusion and crystalloid co-loading for the prevention of…
- Conditions
- Hypotension, Obstetric Anesthesia Problems, Cesarean Section Complications, Hypotensive
- Trial name
- annie-manos (NCT04406051)
- Testing
- norepinephrine infusion and colloid preloading (NOR-COL), norepinephrine infusion and crystalloid co-loading (NOR-CRYST)
- Where
- 2 sites in Greece
- Volunteers
- 100 people
- Sponsor
- Aretaieion University Hospital
Anesthesia
Ilioinguinal/Iliohypogastric Block for Inguinal Hernia Repair
Inguinal hernia have traditionally been done under general anesthesia. While safe, general anesthesia is associated with potential postoperative nausea/vomiting and drowsiness.
- Trial name
- NCT05335837
- Testing
- Regional Anesthesia and Sedation
- Where
- Canada
- Volunteers
- 350 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lung Collapse, One-lung Ventilation
Brief Bronchial Suction for Lung Collapse During Uniportal VATS
The goal of this clinical trial is to learn whether a brief suction of the airway going to the surgical lung (bronchus) can help the lung collapse faster and more completely during uniportal video-assisted thoracoscopic surgery…
- Conditions
- Lung Collapse, One-lung Ventilation, Thoracic Anesthesia, Thoracic Surgery, Video-assisted
- Trial name
- NCT07660588
- Testing
- bronchial suction
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Remimazolam, Total Intravenous Anesthesia
Remimazolam TIVA-Flumazenil Antagonism in Short-duration ENT Surgeries
This study plans to categorize patients who underwent short-duration ENT surgeries with remimazolam TIVA combined with flumazenil antagonism based on whether their intraoperative BIS values were maintained below 60.
- Conditions
- Remimazolam, Total Intravenous Anesthesia, Bispectral Index
- Trial name
- TIVA (NCT07389798)
- Where
- China
- Volunteers
- 511 people
- Sponsor
- Tongji Hospital
Intravenous Anesthesia, Cholelithiasis
Time to Loss of Consciousness With Remimazolam Versus Propofol for Anesthetic Induction in Laparoscopic Cholecystectomy
The goal of this clinical trial is to compare two medicines used to induce general anesthesia in adults undergoing elective laparoscopic cholecystectomy.
- Trial name
- REMIPROP-LOC (NCT07717684)
- Testing
- Remimazolam, Propofol
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Universidade Federal de Sergipe
Pregnancy Complications, Cesarean Section Complications
A Quality Improvement Project - Peripartum Operating Room Leveling System
Investigators propose a four-category triaging system to delineate and facilitate the communication and action plan for all types of obstetric OR cases via a multidisciplinary approach.
- Conditions
- Pregnancy Complications, Cesarean Section Complications, Morbidity;Perinatal
- Trial name
- NCT03552419
- Volunteers
- 1,380 people
- Sponsor
- Johns Hopkins University
Neuromuscular Block, Residual, Pain Management
Methylprednisolone vs Dexamethasone Interaction With Sugammadex in Pediatric Patients
This randomized controlled trial aims to compare the interaction of methylprednisolone and dexamethasone with sugammadex in pediatric patients undergoing adenoidectomy and/or tonsillectomy.
- Conditions
- Neuromuscular Block, Residual, Pain Management, Postoperative Nausea
- Trial name
- NCT07175623
- Testing
- Methyl Prednisolone (MP), Dexamethasone (0.2 mg/kg), Saline (0.9% NaCl)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya City Hospital
Patients Undergoing Elective Craniotomy
Conversion From Total Intravenous Anesthesia Technique to Desflurane Anesthesia for Long Duration Neurosurgery
Since neurological testing during neurosurgery, such as somato-sensory evoked potentials, motor-evoked potentials, auditory evoked potentials and visual evoked potentials are well maintained their wave-form reactivity with total…
- Trial name
- NCT01985854
- Testing
- Propofol, Desflurane
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Tokyo Women's Medical University
Ankle Disease, Ankle Injuries and Disorders
Dexmedetomidine Vs Dexamethasone in Popliteal Nerve Block
Effect of Perineural Dexmedetomidine vs. Dexamethasone on the duration of popliteal nerve block for Anesthesia After Pediatric ankle/foot surgery.
- Conditions
- Ankle Disease, Ankle Injuries and Disorders, Foot Injury, Foot Diseases
- Trial name
- NCT06304324
- Testing
- 0.9% Sodium chloride, 0.1mg/kg Dexamethasone, 0.05ug/kg Dexmedetomidine
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Regional Anesthesia Block, Upper Limb Surgery
An Integrated Artificial Intelligence Approach for Predicting Analgesic Time Based on Nalbuphine Versus Morphine as Adjuvants to Bupivacaine in Ultrasound-Guided Supraclavicular Block
This study investigated the effect of adding nalbuphine or morphine to bupivacaine for supraclavicular brachial plexus block in upper limb surgeries.
- Trial name
- NCT07008443
- Testing
- Bupivacaine + saline, Bupivacaine + nalbuphine, Bupivacaine + morphine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alzahraa Ahmed Abbas