Clinical trials: Anesthesia Time
Bimalleolar Fractures of the Ankle., Sciatic Nerve Block.
To Compare lidocaine2%/Clonidine in Combination, With Bupivacaine 0.5 % Alone in Equal Volumes for Combined Sciatic-saphenous Nerve Block in Terms of Selectivity of Blockade
Clonidine as an adjuvant to local anaesthetics prolongs the postoperative analgesia. It is predominantly an alpha 2 agonist, but does have some alpha 1 activity. Clonidine alone produces analgesia.
- Conditions
- Bimalleolar Fractures of the Ankle., Sciatic Nerve Block., Saphenous Nerve Block., Post Operative Analgesia Duration.
- Trial name
- NCT01759524
- Testing
- Bupivacaine, Lidocaine
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Cork University Hospital
Postoperative Pain, Peripheral Neuropathy
Duration of Blockade of Peripheral Nerves With Bupivacaine Depending of the Adjuvants
The main aim of the investigator's study is to propose combination of local anesthetics and adjuvants that provides both adequate anesthesia during surgery and prolonged post-operative analgesia.
- Conditions
- Postoperative Pain, Peripheral Neuropathy, Fractures of the Upper Limb, Fracture of the Lower Limb (Except Hip), Initial Encounter
- Trial name
- DBBA (NCT04498923)
- Testing
- Bupivacaine, dexamethasone, epinephrine
- Where
- Ukraine
- Volunteers
- 68 people
- Sponsor
- Lviv National Medical University
Hip Disease, Hypotension
Hypotension Probability Index in Anesthesia
The aim of the study is to investigate the value of the Hypotension Probability Index in reducing intraoperative hypotension in patients with primary hip replacement.
- Conditions
- Hip Disease, Hypotension, Surgery, Anesthesia
- Trial name
- NCT03663270
- Testing
- Hypotension probability index (HPI)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Giessen
Post Operative Pain, Distal Radius Fracture
Low Dose Dexamethasone for Distal Radius Fractures
The addition of the steroid dexamethasone to a single injection of local anesthetic has been shown to significantly prolong the duration of peripheral nerve blockade compared to local anesthetic alone.
- Trial name
- NCT05274113
- Testing
- Dexamethasone 4mg, Ropivacaine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Hypotension
ET 50 for Post Caesarean Section Spinal Hypotension
Hypotension is extremely common after induction of spinal anesthesia for cesarean delivery. Anesthetic blockade of the sympathetic outflow of the spinal cord causes vasodilation, and is one cause of this hypotension.
- Trial name
- ET-50 (NCT01561274)
- Testing
- 2 ml bupivacaine, 1.5 ml bupivicaine.
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Body Weight, Obesity
The Optimum Time for Preoxygenation Based on Body Mass Index
The purpose of this study is to evaluate the relationship between the time needed to raise the oxygen concentration in patient's blood to 90% and his/or her body mass index.
- Trial name
- NCT01114932
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Cedars-Sinai Medical Center
Noise Exposure
The Effect of a Reduced Noise Environment on the Response Time of the Anesthesia Provider
This project will investigate whether reduction in ambient light and elimination of noise during induction and emergence from anesthesia influences the response time of the anesthesia provider to auditory and visual alarms when…
- Trial name
- NCT03507855
- Testing
- Reduced noise, Normal
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Joshua Uffman
Anesthesia; Reaction
Endotracheal Intubation With Sevoflurane in Surgical Pediatric Patients
Aim of the study is to compare the optimal time needed for successful tracheal intubation with immediate 8% sevoflurane and incremental sevoflurane induction in surgical pediatric patients undergoing adenotonsillectomy without…
- Trial name
- NCT02429323
- Testing
- Sevoflurane
- Volunteers
- 100 people
- Sponsor
- University of Sulaimani
Postoperative Pain
Postoperative Pain and Recovery Time After Pulpotomy
The aim of this retrospective study was to compare immediate postoperative pain scores and the need for rescue analgesia in children who underwent pulpotomies and general restorative treatment and those who underwent general…
- Trial name
- NCT03142672
- Testing
- pulpotomy, tooth filling
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Pulmonary Aspiration of Gastric Contents
Comparison of Different Preoperative Fasting Times in Pediatric Patients Undergoing Elective General Anaesthesia
Rationale of this study is to provide an evidence on minimal safe clear fluid fasting duration without the risk of aspiration of gastric contents during elective pediatric procedures under general anesthesia.
- Trial name
- NCT05922072
- Testing
- Nasogastric aspiration for measurement of Residual Gastric Volume, Nasogastric Aspiration for Measurement of Gastric pH
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- King Edward Medical University
Obesity, Morbid
EPO2-A: Evaluation of Pre-Oxygenation in Morbid Obesity: Effect of Position and Positive Pressure Ventilation
The risk of complication associated with airway in obese patient is important. The result of pre-oxygenation gives the clinician a prolonged non-hypoxic apnea time.
- Trial name
- EPO2-A (NCT02590406)
- Testing
- Beach chair (BC) and ZEEP, Reverse Trendelenburg and NIPPV
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Laval University
Orthopedic Surgical Procedures, Postoperative Pain
Duration of Sciatic Nerve Block After Injection of Local Anesthetic In or Around the Nerve
This study was designed to assess whether the injection of local anesthetic into the nerve (intraneural), as opposed to around it (perineural), leads to longer anesthesia and analgesia of the leg.
- Trial name
- NCT01981291
- Testing
- Intraneural Injection for Subgluteal Sciatic Nerve Block, Perineural Injection for Subgluteal Sciatic Nerve Block, Femoral Nerve Block
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Parma
Paraspinal Muscle Mass and Spinal Anaesthesia
Non-Pharmacological Factors on Spinal Block Duration
The aim of this study is to evaluate the effects of non-pharmacological factors-such as age, sex, body mass index, paraspinal muscle mass, vertebral canal anatomy, patient positioning, and injection technique-on the duration of…
- Trial name
- NCT07638280
- Testing
- spinal anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Postoperative Complications, Delayed Emergence From Anesthesia
EEG-based Depth of Anesthesia-monitoring, Effects on Dosage and Cognition
Depth of anesthesia-monitoring based on EEG changes demands knowledge about the effects of the different anesthetic medications on EEG waveforms.
- Conditions
- Postoperative Complications, Delayed Emergence From Anesthesia, Cognitive Dysfunction
- Trial name
- NCT04529304
- Testing
- Bilateral Bispectral Index and EEG
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Depression
Hyperventilation Combined With Etomidate or Ketamine Anesthesia in ECT Treatment of Major Depression
This is a randomized controlled study assessing the effect of pre-emptive hyperventilation on ECT seizure duration, cerebral desaturation and remission of depressive symptoms in patients with Major Depressive Disorder.
- Trial name
- NCT02924090
- Testing
- Etomidate, Ketamine, Hyperventilation
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Manitoba
Anesthesia
Study of Rocuronium Onset Time According to Remifentanil Infusion
The investigators therefore hypothesized that remifentanil could prolong the onset time of rocuronium, and evaluated the effect of remifentanil on the hemodynamic profiles (arterial pressure and heart rate) during the anesthetic…
- Trial name
- NCT01030510
- Testing
- the order of drug administration
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Seoul National University Bundang Hospital
Orthopedic Disorder
The Duration of Spinal Anaesthesia - a Prospective, Observational Cohort Study
Today, surgery in an ambulatory setting is preferred for many reasons. Total hip and knee arthroplasty (THA and TKA) are now procedures where patients can be sent home on the same day of the surgical procedure.
- Trial name
- Spinalrocks (NCT06459986)
- Where
- 2 sites in Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Spinal Anesthesia, Prolonged Sensory Block
Impact of Intravenous Dexamethasone on the Duration of Motor and Sensory Block Following Spinal Anesthesia With Chloroprocaine
The purpose of this study is to compare the effect of a single dose of 8 mg of intravenous dexamethasone versus placebo on the duration of sensory and motor block after spinal anesthesia with chloroprocaine.
- Conditions
- Spinal Anesthesia, Prolonged Sensory Block, Prolonged Motor Block
- Trial name
- NCT07837674
- Testing
- Intravenous Dexamethasone, Normal Saline
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Rib Fractures
Continuous Intercostal Nerve Blockade for Traumatic Rib Fractures
Rib fractures are common injuries in accident patients and can be associated with significant pain during recovery. If poorly controlled, pain from splinting due to rib fractures can result in difficulty in breathing leading to…
- Trial name
- NCT02604589
- Testing
- hydromorphone hydrochloride, Infusion catheter placement, bupivicaine 0.25%
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Anthony Iacco
Dexamethasone, Spinal Anesthesia
Dexamethasone and Duration of Spinal Anesthesia
This study will evaluate whether intravenous dexamethasone affects the duration of spinal anesthesia in patients undergoing lower abdominal surgery.
- Conditions
- Dexamethasone, Spinal Anesthesia, Adjuvant
- Trial name
- NCT07819682
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Pakistan