Clinical trials: Anesthesia and Analgesia
Anesthesia, Pain
Combined Spinal Epidural Urinary Retention
The investigators hypothesize that many parturients can, in fact, spontaneously micturate with low dose combined spinal epidural analgesic doses given for labor and that Foley catheterization is unnecessary in the majority of…
- Conditions
- Anesthesia, Pain, Urinary Retention
- Trial name
- NCT01597791
- Testing
- Foley catheter, No foley catheter
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Northwestern University
Anesthesia, Regional Anesthesia Morbidity
Feasibility of Serratus Plane Block Associated With Sedation in Axillary Dissection
INTRODUCTION: The axillary lymphadenectomy procedure is known to be associated with late postoperative complications, such as chronic pain and changes in shoulder mobility.
- Conditions
- Anesthesia, Regional Anesthesia Morbidity, Axillary Metastases, Nerve Block
- Trial name
- NCT03740815
- Testing
- Serratus plane block, Axillary dissection, Intravenous sedation
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Pain Management
Adductor Canal Block After Total Knee Replacement - a Suture-method Catheter vs a Standard Catheter vs a Single Bolus
In this study we wish to investigate the analgesic effect of the administration of 0.2% ropivacaine for an adductor canal block as repeated boluses (20 ml every 8 hours) through a new suture-method catheter or a standard…
- Trial name
- NCT03142789
- Testing
- Initial bolus (Certa and standard catheter groups), Initial bolus (Single bolus group), Intermittent boluses (Certa and standard catheter groups)
- Where
- Denmark
- Volunteers
- 153 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Arthroscopic Shoulder Surgery
Interscalene Versus Infraspinatus-Teres Minor Blocks for Arthroscopic Shoulder Surgery
This randomized controlled trial aims to compare the effectiveness of interscalene (ISB) and infraspinatus-teres minor (ITM) blocks for postoperative analgesia in patients undergoing elective arthroscopic shoulder surgery.
- Trial name
- ITM-ISB (NCT07253740)
- Testing
- Interscalene Brachial Plexus Block (ISB), Infraspinatus-Teres Minor Block (ITM)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Breast Cancer, Postoperative Pain
Effectiveness of Ultrasound Guided Erector Spinae Plane Block Against Ultrasound Guided Serratus Anterior Block in Modified Radical Mastectomy
The aim of this study is to compare and evaluate the safety and analgesic efficacy of ultrasound guided ESP block and ultrasound guided serratus anterior plane block in patients undergoing modified radical mastectomy.
- Trial name
- NCT04606147
- Testing
- Serratus Anterior Plane Block, Erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Pain, Analgesia
Fascia Iliaca Block Versus Intravenous Dexmedetomidine and Ketamine for Positioning Fracture Femur
Proximal femur fractures are one of the commonest fractures especially in the elderly population. Early surgical fixation is the best analgesic for associated pain.
- Trial name
- NCT05705726
- Testing
- ultrasound guided facia iliaca block, Intravenous drug
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Minia University
Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV)
Dexamethasone to Prevent Side Effects of Spinal Anesthesia in Cesarean Delivery
The goal of this clinical trial is to evaluate the effectiveness of intravenous dexamethasone in preventing adverse effects of spinal anesthesia and prolonging postoperative analgesia in parturients undergoing elective cesarean…
- Conditions
- Hypotension During Cesarean Delivery, Postoperative Nausea and Vomiting (PONV), Pain, Postoperative
- Trial name
- NCT07615595
- Testing
- Dexamethasone
- Where
- Vietnam
- Volunteers
- 176 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Inguinal Hernia, Postoperative Pain
Ultrasound-Guided Ilioinguinal-Iliohypogastric Nerve Block Following Spinal Anesthesia Comparing Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Unilateral Inguinal Hernia Repair
This study evaluates and compares the pain-relieving efficacy and safety of adding either dexmedetomidine or nalbuphine to bupivacaine in an ultrasound-guided ilioinguinal-iliohypogastric nerve block for patients undergoing…
- Trial name
- NCT07837492
- Testing
- Bupivacaine, Nalbuphine, Dexmedetomidine
- Volunteers
- 102 people
- Sponsor
- Assiut University
Osteo Arthritis Knee, Analgesia
Comparing Local Anesthesia With and Without iPACK Block
Total knee arthroplasty is an effective surgical intervention for patients with chronic osteoarthritis commonly performed worldwide. Postoperative pain management has been a key focus in patient care for this procedure.
- Conditions
- Osteo Arthritis Knee, Analgesia, Pain, Postoperative
- Trial name
- NCT04635176
- Testing
- Real iPACK block (20 mL of 0.25% bupivacaine, 2.5mcg/mL epinephrine, and 50mcg/mL preservative-free dexamethasone)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Calgary
Scheduled Laparoscopic Surgery
Pupillary Reflex Measurement to Guide Intraoperative Analgesia During Laparoscopic Surgery
The purpose of this study is to determine whether analgesia guided by pupillary reflex during laparoscopic surgery is effective in opioid sparing (intraoperative remifentanil and postoperative morphine).This is a prospective…
- Trial name
- NCT02116868
- Testing
- Pupillometry guided analgesia (PP), Tailored remifentanil controlled infusion, Tailored antihypertensive drug administration
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Central Hospital, Nancy, France
Hip Fractures, Anesthesia Local
Shamrock Versus Lumbar Ultrasound Trident - Ultrasound Guided Block of the Lumbar Plexus
The main objective of the trial is to complete a double-blinded randomized controlled trial of a lumbar plexus block with the Shamrock technique versus the Lumbar Ultrasound Trident technique by estimating the time of performance…
- Conditions
- Hip Fractures, Anesthesia Local, Pain, Postoperative
- Trial name
- NCT02255591
- Testing
- Lidocaine-adrenaline added gadolinium.
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Anesthesia and Analgesia, Magnesium Sulfate
Clinical Response to Magnesium Sulfate as an Adjunct in the Anesthesia
Magnesium sulfate (MgSO4) has multiple desirable effects in an anesthetic procedure, including modulation of the hemodynamic response to surgical stress, perioperative anesthetic and analgesic effect, potentiation of…
- Trial name
- NCT05227716
- Testing
- Perioperative magnesium sulfate
- Where
- 2 sites in Mexico
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Pain, Acute, Analgesia
Retrospective Evaluation of Ketamine Effectiveness for the Treatment of Acute Battlefield Related Pain
Using a retrospective review of records, we will conduct a multivariate analysis to examine the relationship between exposure to ketamine, as an analgesic agent in combat related trauma care, the use of additional opioid pain…
- Conditions
- Pain, Acute, Analgesia, Amputation, Traumatic, Post Traumatic Stress Disorder
- Trial name
- NCT04057989
- Testing
- ketamine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Cholelithiasis, Postoperative Pain, Laparoscopic Cholecystectomy
ESP vs Subcostal TAP Block for Analgesia After Laparoscopic Cholecystectomy
This prospective, randomized, double-blind study compares the analgesic efficacy of ultrasound-guided erector spinae plane (ESP) block and subcostal transversus abdominis plane (TAP) block in patients undergoing laparoscopic…
- Trial name
- ESP TAP (NCT07661693)
- Testing
- Erector Spinae Plane Block, Subcostal Transversus Abdominis Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gaziantep City Hospital
Local Anesthesia
Efficacy and Safety of Lambdalina (Lidocaine Cream) Versus Placebo as an Anesthetic for Laser Hair Removal
Double-blind, randomized, placebo-controlled trial to assess the efficacy of Lambdalina (lidocaine cream) in reducing pain associated with laser hair removal in women.
- Trial name
- NCT01360749
- Testing
- Lambdalina® (Lidocaine 4% cream)
- Where
- 2 sites in Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- ISDIN
Postoperative Pain Management, Postoperative Nausea and Vomiting
LAPOFAR Trial: Opioid-Free vs. Remifentanil Anesthesia in Laparoscopic Cholecystectomy
This study was a single-center, prospective, randomized clinical trial designed to compare the effects of opioid-free anesthesia (OFA) with standard opioid-based anesthesia during elective laparoscopic cholecystectomy.
- Conditions
- Postoperative Pain Management, Postoperative Nausea and Vomiting, Laparoscopic Cholecystectomy, Opioid-free Anesthesia
- Trial name
- LAPOFAR (NCT07307625)
- Testing
- Lidocaine + Dexmedetomidine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Postoperative Pain, Lumbar Spine Surgery
Effect of Ultrasound-Guided Quadro-Iliac Plane Block on Postoperative Analgesia After Lumbar Spinal Surgery
This prospective observational study aims to evaluate the effect of ultrasound-guided Quadro-Iliac Plane Block (QIPB) on postoperative analgesia in patients undergoing lumbar spinal surgery.
- Conditions
- Postoperative Pain, Lumbar Spine Surgery, Postoperative Analgesia
- Trial name
- NCT07326774
- Testing
- QIPB, LAI
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Pain, Anesthesia
NoL and BIS Monitoring on Patients Recovery and Safety After Surgery
So far, only vital signs (mostly, blood pressure and heart rate) helped the anesthesiologist to administer hypnotic agents or analgesics.
- Trial name
- CINAAMON (NCT03410485)
- Testing
- BIS index/NoL index, Variation of baseline mean arterial pressure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Lacerations, Wound Repair
Pain Experience Using Lidocaine Adrenaline Tetracaine (LAT) Gel Versus Lidocaine Infiltration for Laceration Repair in Adults
This prospective comparative study evaluates pain experience in adult patients undergoing laceration repair in the emergency department using either topical lidocaine-adrenaline-tetracaine (LAT) gel or lidocaine infiltration as…
- Conditions
- Lacerations, Wound Repair, Acute Traumatic Wounds, Pain Management
- Trial name
- NCT07480135
- Testing
- Lidocaine-Adrenaline-Tetracaine (LAT) Gel, Lidocaine infiltration
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Vrije Universiteit Brussel
Ultrasound Guided Nerve Block, Anesthesia , Analgesia
Comparative Study Between Ultrasound Guided Regional Anesthesia for Awake Tympanoplasty Surgery vs General Anesthesia
The aim of this study to evaluate efficacy of ultrasound guided regional anesthesia in performing awake tympanoplasty surgery versus traditional general anesthesia
- Trial name
- NCT07275450
- Testing
- Ultrasound-guided regional anesthesia group, Control group
- Where
- Egypt
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Zagazig University
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