Clinical trials: Anesthesia and Analgesia
Adolescent Idiopathic Scoliosis, Multimodal Analgesia
Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery
Patients with Adolescent Idiopathic Scoliosis may need surgery to correct their scoliosis. General anesthesia is required for this surgery, and a multimodal analgesic regimen using combinations of opioid and non-opioid…
- Conditions
- Adolescent Idiopathic Scoliosis, Multimodal Analgesia, Opioid Induced Hyperalgesia, Remifentanil
- Trial name
- NCT06096181
- Testing
- Remifentanil TIVA, Dexmedetomidine TIVA, Propofol TIVA
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Colon Cancer
Regional Anesthesia in Colon Rectal Surgery
This study will compare recurrence rates in patients with colorectal cancer who will be randomly assigned to epidural anesthesia/analgesia combined with general anesthesia or to general anesthesia followed by opioid analgesia.
- Trial name
- NCT00684229
- Testing
- Regional anesthesia and analgesia, general anesthesia followed by opioid analgesia
- Where
- 3 sites in United States, Argentina and 1 more
- Sponsor
- The Cleveland Clinic
Postoperative Analgesia, Pain Management
Erector Spinae Plane Block Versus Retrolaminar Block for Analgesia in Percutaneous Nephrolithotomy
The study will investigate the effects of ultrasound-guided ESPB and RLB on intraoperative and postoperative analgesia in patients undergoing PCNL to identify a safe and effective regional block method for postoperative analgesia
- Conditions
- Postoperative Analgesia, Pain Management, PCNL, Regional Anesthesia Block
- Trial name
- NCT06710444
- Testing
- ultrasound-guided erector spinae plane block, ultrasound-guided retrolaminar plane block
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Alexandria University
Pain, Postoperative, Pain, Acute
Nurse Initiated Acupressure for Pain Management
The purpose of pilot study is to test the feasibility of nurse initiated post-operative bilateral auricular acupressure as an adjunct to medication for post-operative pain management.
- Trial name
- NCT04044716
- Testing
- Auricular acupressure, Standard of care pain management
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Wake Forest University Health Sciences
Analgesia, Pain, Postoperative
Comparison Between the Caudal Block and Other Methods of Postoperative Pain Relief in Children Undergoing Circumcision
Prospective, randomized, case-controlled trial study. Observation post-operatively: Aims: This study aimed to compare the effectiveness of the caudal block CB with other methods of postoperative pain release.
- Conditions
- Analgesia, Pain, Postoperative, Pain, Acute
- Trial name
- paincontrol (NCT06086106)
- Testing
- caudal block, Dorsal Penile Nerve Block DPNB, Systemic opioids
- Where
- Bahrain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Salmaniya Medical Complex
Analgesia After Pacemaker, AICDS Implantation Pediatrics
Truncal Ultrasound Guided Regional Anesthesia for Implantation and Revision of Automatic Implantable Cardioverter Defibrillators (AICDs) and Pacemakers in Pediatric Patients
The purpose of this study is to determine the efficacy and safety of truncal blocks for pacemaker and Automatic Implantable Cardioverter Defibrillator implantation in children and to prospectively evaluate whether there is a…
- Trial name
- NCT04184349
- Testing
- LA group, B Group
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- The University of Texas Health Science Center, Houston
Local Anesthesia, Analgesia Disorder
Intermediate Cervical Block Under Ultrasound for Thyroid Surgery: Impact on Per and Postoperative Opioid Consumption
The investigators included prospectively 35 patients undergoing an intermediate cervical block under ultrasound (GP1) before a thyroidectomy ,compared to a group of 35 patients without a block (GP2).
- Trial name
- ICPBUS (NCT03107585)
- Testing
- bilateral cervical plexus block
- Where
- Tunisia
- Volunteers
- 70 people
- Sponsor
- University Hospital, Mahdia
Knee Osteoarthritis, Postoperative Pain
Ultrasound-Guided PASC Block vs Femoral-Sciatic Nerve Block for Postoperative Analgesia After Total Knee Arthroplasty
This randomized, double-blind comparative study evaluates postoperative analgesic efficacy and motor effects of ultrasound-guided para-sartorial compartments (PASC) block versus ultrasound-guided combined femoral-sciatic nerve…
- Conditions
- Knee Osteoarthritis, Postoperative Pain, Total Knee Arthroplasty
- Trial name
- NCT07320833
- Testing
- Ultrasound-Guided Femoral Nerve Block plus Sciatic Nerve Block, Ultrasound-Guided Para-sartorial Compartments Block
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Ain Shams University
Pain, Acute, Knee Arthropathy
Comparison of Regional Anesthesia Techniques After Total Knee Arthroplasty
Comparison of continuous adductor canal block to continuous femoral nerve block in patients after total knee arthroplasty. All patients will be anesthetized with spinal anesthesia.
- Conditions
- Pain, Acute, Knee Arthropathy, Postoperative Pain, Mobility Limitation
- Trial name
- NCT03143738
- Testing
- continuous anesthesia of adductor canal, continuous anesthesia of femoral nerve, Spinal anesthesia
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Lublin
Postoperative Pain, Anesthesia, Local
Additional Effect of Wound Infiltration After Cesarean Section With Optimal Standard Analgesia
The purpose of this study is to determine wether wound infiltration brings additional analgesia effect after cesarean section with optimal standard postoperative analgesia
- Conditions
- Postoperative Pain, Anesthesia, Local, Breast Feeding
- Trial name
- KTcesar (NCT01751256)
- Testing
- Continuous wound infiltration
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Poissy-Saint Germain Hospital
Dexmedetomidine
Dexmedetomidine and Sufentanil Effect in PCA on Pediatric Patients Undergoing Scoliosis Surgery
The primary purpose of this three-arm single center, randomized, subject and assessor blind, controlled clinical study is to evaluate the effect of dexmedetomidine on patient-controlled intravenous analgesia after pediatric…
- Trial name
- DEX (NCT05249153)
- Testing
- low dose of dexmedetomidine with sufentanil, high dose of dexmedetomidine with sufentanil
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Peking Union Medical College Hospital
Quality of Recovery After Mastectomy, Serratus Anterior Plane Block
Timing of Serratus Anterior Plane Block in Mastectomy Surgery
Postoperative pain following mastectomy may adversely affect early mobilization, patient comfort, and overall quality of recovery.
- Conditions
- Quality of Recovery After Mastectomy, Serratus Anterior Plane Block, Postoperative Pain, Mastectomy
- Trial name
- NCT07661212
- Testing
- Ultrasound-Guided Serratus Anterior Plane Block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Analgesia
The Effect of Combined Spinal Epidural Anaesthesia on QTc Interval Undergoing Cesarean Section
Cesarean section is the operation to deliver the fetus, placenta and membranes by making an abdominal incision in the uterus. Cesarean section is performed for reasons such as head-pelvis incompatibility, fetal malposition, fetal…
- Trial name
- NCT06018805
- Testing
- BMI≥30; Combined Spinal Epidural Anesthesia, BMI:18,5-24,9; Combined Spinal Epidural Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Anesthesia, Gynecologic Cancer
ESP vs TAP in Total Laparoscopic Hysterectomy
The anesthetic techniques for videolaparoscopic surgery include general anesthesia, and locoregional anesthesia in association with general anesthesia in order to reduce or abolish post-operative pain with a simultaneous…
- Trial name
- ARTEMIDE (NCT04839445)
- Testing
- General anesthesia + TAP block, General anesthesia + ESP block
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- AUSL Romagna Rimini
Pain Insensitivity, Congenital
Comparison of Levobupivacaine, Ropivacaine and Bupivacaine in Epidural Anaesthesia
This study compares the clinical efficacy of newer local anaesthetic drugs Levobupivacaine and Ropivacaine with Bupivacaine in lumbar epidural anaesthesia for hip surgeries.
- Trial name
- NCT02513433
- Testing
- Bupivacaine, Levobupivacaine, Ropivacaine
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Government Medical College, Haldwani
Pain, Postoperative
Effectiveness of Adductor Canal Block Using Liposomal Bupivacaine
With aging of population, osteoarthritis of knees and hips become major orthopaedic problems in Hong Kong. Osteoarthritis of knees and hips are associated with significant pain problem and functional disability.
- Trial name
- NCT04003506
- Testing
- Liposomal bupivacaine, Bupivacaine Injection
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The University of Hong Kong
Obstetric Pain, Obstetric Anesthesia Problems
TAP Block vs LAWI for Analgesia Post-cesarean Section: RCT
Adequate pain control after cesarean delivery is a significant concern both for parturients and obstetric anesthesiologists. Transversus Abdominis Plane (TAP) block and local Wound infiltration with anesthetics are alternatives…
- Trial name
- NCT04637386
- Testing
- Transversus Abdominis Plane Block, Local anesthetic wound infiltration
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Brachial Plexus Anesthesia, Analgesia
Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia
Adding dexamethasone to local anesthetic will significantly prolong duration of brachial plexus anesthesia and analgesia.
- Trial name
- NCT01739270
- Testing
- supraclavicular brachial plexus block
- Where
- Croatia
- Volunteers
- 55 people
- Sponsor
- University Hospital Dubrava
Ventral Hernia, Postoperative Pain
Evaluation of Ultrasound-guided Erector Spinae Block for Postoperative Analgesia in Laprascopic Ventral Hernia Repair.
Ventral hernia repair is associated with significant postoperative pain, and regional anesthetic techniques are of potential benefit.
- Conditions
- Ventral Hernia, Postoperative Pain, Regional Anesthesia
- Trial name
- NCT04438369
- Testing
- Erector Spinae Plane Block
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Ostfold Hospital Trust
Analgesia, Anesthesia
Comparison of Paravertebral Block and Subcostal Transversus Abdominis Plane Block in Laparoscopic Nephrectomy
Most of the patients undergoing laparoscopic partial/radical nephrectomy can experience moderate or severe postoperative pain, and inadequate control of this pain can cause negative consequences such as development of chronic…
- Conditions
- Analgesia, Anesthesia, Pain, Postoperative
- Trial name
- NCT05723341
- Testing
- Bupivacain, Morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Istanbul University
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