Clinical trials: Anesthesia and Analgesia
Anesthesia, Anesthesia , Analgesia
Artificial Intelligence vs. Automated Messaging for Continuous Regional Analgesia Follow-up
Effective postoperative analgesia is critical for patient recovery, satisfaction, and the reduction of hospital stay duration. Continuous peripheral nerve blocks (CPNB) via catheter placement represent a cornerstone in achieving…
- Conditions
- Anesthesia, Anesthesia , Analgesia, Regional Anesthesia, Regional Anesthesia Success
- Trial name
- NCT07510425
- Testing
- AI-driven follow-up platform, Satisfaction, Adherence to the follow-up protocol
- Where
- Chile
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Inguinal Hernia Unilateral, Postoperative Pain Management
Transversalis Fascia Plane Block Versus Surgical Wound Infiltration for Postoperative Analgesia in Open Inguinal Hernia Repair
The purpose of this clinical trial is to evaluate whether two different analgesic techniques - ultrasound-guided Transversalis Fascia Plane Block (TFPB) and surgical wound infiltration - can improve postoperative pain control in…
- Conditions
- Inguinal Hernia Unilateral, Postoperative Pain Management, Regional Anaesthesia, Transversalis Fascia Plane Block
- Trial name
- TFPB-WIN (NCT07238829)
- Testing
- Ultrasound-Guided Transversalis Fascia Plane Block (TFPB), Surgical Wound Infiltration
- Volunteers
- 104 people
- Sponsor
- Ondokuz Mayıs University
Pain, Postoperative, Analgesia
Analgesia Nociception Index (ANI) in Intracranial Surgical Anesthesia
In our study, 75 patients aged 18-80 years, classified as ASA I-II risk groups, who underwent intracranial surgery performed by the Department of Neurosurgery at Trakya University Faculty of Medicine Hospital, were included.
- Conditions
- Pain, Postoperative, Analgesia, Supratentorial Brain Tumor, Infratentorial Neoplasms
- Trial name
- ANI (NCT06752824)
- Testing
- ANALGESIA NOCICEPTION INDEX MONITORING
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Trakya University
Spinal Diseases, Local Anesthesia
The Effect of Dexmedetomidine Analgesia and Sedation in Minimally Invasive Spine Surgery Under Local Anesthesia
Evaluate safety and efficacy of dexmedetomidine in minimally invasive spine surgery under local anesthesia sedation.Explore the appropriate concentration of dexmedetomidine, whether or not can reduce the amount of local…
- Trial name
- NCT02535273
- Testing
- Dexmedetomidine, Lidocaine, Low-dose Dexmedetomidine
- Volunteers
- 212 people
- Sponsor
- Tang-Du Hospital
Anesthesia, Local
Can a Subcostal Nerve Block Add Benefit to a Lateral Femoral Cutaneous Nerve Block for Open Hip Surgery
Hip Surgery is a very common form of surgery carried out across many hospitals within the UK in emergency and elective form. There is a variation between amongst surgeons with regard to the initial surgical incision required for…
- Trial name
- NCT04779580
- Testing
- Lateral Cutaneous Nerve Of The Thigh Nerve Block Using Local Anaesthetic, Subcostal Nerve Block Using Local Anaesthetic
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Queen Elizabeth Hospital King's Lynn NHS Foundation Trust
Pain, Anesthesia
Effects of Anesthetic Technique on NK Cells
The proposed study is a pilot prospective, single-blinded, randomized controlled trial evaluating the effects of two routine, standard-of-care, anesthetic techniques on natural killer cell population size and cytotoxicity in…
- Conditions
- Pain, Anesthesia, Cancer
- Trial name
- NCT02669186
- Testing
- Bupivacaine + Fentanyl, Bupivacaine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Anesthesia, Epidural, Analgesia, Epidural
"Compuflo®" in Epidural Space Identification
Recently a computerized injection pump has been programmed with its own mathematical algorithm to measure on a digital display the pressure trend in the form of a continuous curve and it has been connected to an acoustic device…
- Trial name
- NCT03503656
- Testing
- epidural catheter placement
- Volunteers
- 140 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Anesthesia
Comparison of Different Analgesia-Monitors in Tracing Unconscious Pain Sensations
Until today there is no standard-monitoring to specifically reflect the analgesic component of general anesthesia. Quality and safety of general anesthesia are of major clinical importance and can be improved by limiting the…
- Trial name
- AMUPS (NCT02429960)
- Testing
- Analgesia monitor (PhysioDoloris®), Analgesia monitor (SPI®), Analgesia monitor (AlgiScan®)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Birth
Management of Obstetrical Pain: " 7 Days Survey of Obstetric Analgesia/Anesthesia in France"
Obstetric analgesia is a requirement of our times. The different applicable methods vary in effectiveness. The essential part is represented by epidural analgesia which remains one of the most effective methods.
- Trial name
- Epidol (NCT02853890)
- Testing
- Questionnaires during hospitalization for delivery
- Where
- France
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Postoperative Pain, Postoperative Vomiting
Efficacy of Dexmedetomidine for Postoperative Analgesia in Infantile Cataract Surgery
The purpose of the present study was to evaluate the efficacy and safety of subtenon block (SB)anesthesia with dexmedetomidine in combination with bupivacaine versus intravenous dexmedetomidine for postoperative analgesia and…
- Trial name
- NCT02495220
- Testing
- SB dexmedetomidine bupivacaine block, intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Hysteroscopy
Postoperative Analgesic Efficacy of Tetracaine Hydrochloride Gel
This study was taken out to assess the postoperative analgesic efficacy of tetracaine hydrochloride gel in patients with intrauterine adhesion treating with intrauterine balloon.Participates were assigned into two groups by…
- Trial name
- NCT02863679
- Testing
- Tetracaine hydrochloride gel
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Wenzhou Medical University
Postoperative Pain
Comparing the Effects of M-TAPA and TAP Block on Postoperative Analgesia in TAH
Aim is to compare the postoperative analgesic efficacy of M-TAPA block and TAP block and their effect on opioid consumption in patients undergoing open total abdominal hysterectomy (TAH) surgery.
- Trial name
- NCT05901090
- Testing
- M-TAPA block, TAP block
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Cumhuriyet University
Knee Surgeries, Total Ankle Arthroplasty
Adductor Canal Block With IPACK Versus 4-in-1 Block for Postoperative Analgesia in Knee Surgery
This randomized interventional study compares the analgesic efficacy of Adductor Canal Block combined with Infiltration of the Posterior Capsule of the Knee (IPCAK) versus the 4-in-1 block technique in patients undergoing knee…
- Conditions
- Knee Surgeries, Total Ankle Arthroplasty, Anterior Cruciate Ligament (ACL) Tear, Posterior Cruciate Ligament Tear
- Trial name
- NCT07700797
- Testing
- Adductor canal block with IPACK, 4 in 1 block
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Hip Fractures
Comparison of Pericapsular Nerve Group Block With Suprainguinal Fascia Compartment Block in Hip Fractures
Ultrasound-guided Supra-inguinal Fascia Iliaca compartment Block (SIFCB) and Pericapsular Nerve Group Block (PENG) are increasingly being used for postoperative analgesia for hip surgery.
- Trial name
- NCT06169462
- Testing
- PENG block, PENG block+ SIFCB
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Umbilical Hernia, Obesity
Abdominal Wall Block Study
Compare the ability of the transversus abdominis plane block (TAPB) and rectus sheath block (RSB) to provide surgical anesthesia for overweight and obese patients undergoing umbilical hernia surgery.
- Trial name
- TAPB (NCT03074240)
- Testing
- TAPB Group, RSB Group, conversion to general anesthesia
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Florida
Postoperative Pain
A Pain Study Comparing Two Commonly Used Medications to Treat Pain After Bowel Surgery
This research study is testing whether the local anesthetic lidocaine is as effective as ropivacaine for post-operative pain control in continuous thoracic paravertebral nerve blocks.
- Trial name
- NCT02849678
- Testing
- Ropivacaine, Lidocaine
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Jacques E. Chelly
Pregnancy
Use of Ultrasound in Obstetric Neuraxial Analgesia and Anesthesia Data Base
This is a data base building project on the use of pre-procedure ultrasound for the performance of labor epidural pain relief and spinal anesthesia for cesarean deliveries.
- Trial name
- NCT01192074
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Maternal Anaesthesia and Analgesia Affecting Fetus or Newborn, Breast Feeding
Intrapartum Epidural Fentanyl and Breast-feeding in the Immediate Postpartum Period: a Prospective Cohort Study
Intrapartum epidural analgesia has been associated with adverse breastfeeding outcomes. One potential mechanism involves transfer of epidural fentanyl across the placenta and neonatal blood-brain barrier, where it can…
- Conditions
- Maternal Anaesthesia and Analgesia Affecting Fetus or Newborn, Breast Feeding, Fentanyl, Bupivacaine
- Trial name
- NCT01488149
- Where
- United States
- Sponsor
- University Hospitals Cleveland Medical Center
Anesthesia, Cardiac Surgery
Oral and Intravenous Methadone for Analgesia in Cardiac Surgery
The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anesthesia on postoperative pain for patients undergoing elective cardiac…
- Trial name
- NCT06720415
- Testing
- Oral methadone, immediately prior to transport, Intravenous methadone
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Mayo Clinic
Nephrolithiasis, Postoperative Pain
Effect of a Low-Dose Ketamine-Dexmedetomidine-Based Opioid-Sparing Anesthesia Protocol on Postoperative Quality of Recovery After Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is a minimally invasive surgical procedure used to remove large or complex kidney stones. Although effective, dilation of the surgical tract and the placement of a nephrostomy tube cause…
- Conditions
- Nephrolithiasis, Postoperative Pain, Quality of Recovery
- Trial name
- NCT07855068
- Testing
- Ketamine and Dexmedetomidine, Fentanyl
- Volunteers
- 100 people
- Sponsor
- Assiut University
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