Clinical trials: Anesthesia and Analgesia
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Influence of Maternal Postioning on Spread of Local Anesthetic After Epidural Analgesia
The purpose of this study is to determine if a lateral positioning of the pregnant woman after epidural analgesia increases the incidence of unilateral functioning epidurals.
- Trial name
- NCT02617823
- Testing
- lateral position
- Where
- 2 sites in Sweden
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Region Skane
Postpartum Hemorrhage
Retrospective Evaluation of the Impact of Epidural on the Risk of Postpartum Hemorrhage
Postpartum hemorrhage (PPH) is a major complication of childbirth. Epidurals are often implicated in the onset of postpartum hemorrhages.
- Trial name
- NCT06816654
- Testing
- Data extraction from medical records
- Where
- Belgium
- Volunteers
- 5,753 people
- Sponsor
- Tatiana Besse-Hammer
Analgesia, Pain Management
Clinical Impact of IPACK Block Addition to Suprainguinal Fascia Iliaca Block
In our clinic, routine suprainguinal fascia iliaca block (SIFIB) has been administered for postoperative analgesia in patients undergoing knee arthroplasty.
- Conditions
- Analgesia, Pain Management, Acute Pain
- Trial name
- NCT06054945
- Testing
- SIFIB (suprainguinal fascia iliaca block), IPACK (Interspace between the popliteal artery and capsule of the posterior knee ), Patient controlled anagesia device
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Samsun University
Anesthesia
Efficacy of Virtual Reality Distraction Technique for Anxiety and Pain Control in Orthopedic Forearm Surgeries Performed Under Supraclavicular Brachial Plexus Block
Invistigators hypothesized that using of VR distraction technique during performing peripheral regional anesthesia (supraclavicular block) would lead to better perioperative analgesia and less anxiety.
- Trial name
- NCT05512728
- Testing
- VR, Midazolam
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cancer, Perioperative Analgesia
Combined Pectoserratus and Superficial Cervical Plexus Block Versus Local Infiltration for Chemoport Implantation
Chemoport implantation is frequently performed in patients with cancer requiring long-term intravenous chemotherapy. Local infiltration anesthesia (LIA) remains the conventional anesthetic technique for this procedure.
- Trial name
- NCT07771712
- Testing
- Combined Pectoserratus Plane and Superficial Cervical Plexus Block, Local Infiltration Anesthesia with Bupivacaine 0.25%, Midazolam
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Indonesia
Transurethral Resection of Prostate
Effectiveness of Nalbuphine as an Adjuvant to Subarachnoid Block on Postoperative Analgesia in TURP Surgery
The goal of this clinical trial is to compare pain after surgery in patients undergoing Transurethral Resection of Prostate. The main question it aims to answer are: Intrathecal nalbuphine as an adjuvant to local anesthetic will…
- Trial name
- NCT06153602
- Testing
- Nalbuphine Hydrochloride 10 MG/ML, Sodium Chloride 0.9 % in 5 ML Injection, Bupivacaine Hydrochloride, Spinal
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Chulalongkorn University
Labor Pain
Labor Analgesia With Ropivacaine and Clonidine
The aim of the present study was to examine, for pain relief during labor, the efficacy of two pharmacological approaches - the 0.125% ropivacaine alone and the 0.0625% ropivacaine added to 75 ug clonidine, both by epidural…
- Trial name
- LA (NCT00626977)
- Testing
- ropivacaine, ropivacaine and clonidine
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Anesthesia , Analgesia
Echo-guided Scalp Blocks and Incidence of Postoperative Pain in Scheduled Supratentorial Intracranial Surgery.
Up to 30% of patients undergoing intracranial surgery present moderate to severe pain. In this type of surgery, the restriction of the pharmacopoeia, which goes against the concept of multimodal analgesia, results in the…
- Trial name
- ULTRASCALP (NCT07149077)
- Testing
- Echo-guided scalp blocks, Classic anesthetic strategy
- Where
- France
- Volunteers
- 230 people
- Sponsor
- University Hospital, Bordeaux
Postoperative Pain, Acute, Regional Anesthesia
Comparation of Bilateral and Unilateral Erector Spinae Plane Block
Although laparoscopic cholecystectomy is a minimally invasive surgery with many advantages, it is one of the operations with high postoperative pain scores. Opioids are frequently used to prevent postoperative pain.
- Conditions
- Postoperative Pain, Acute, Regional Anesthesia, Multimodal Analgesia
- Trial name
- NCT05152602
- Testing
- Bilateral Erector spinae plane block, Unilateral Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara City Hospital Bilkent
Surgery of Abdominoplasty With Flank Liposuction
Analgesic Effect Between TAP Block and Continuous Wound Infusion in Abdominoplasty Surgery
The purpose of this randomized controlled study is to compare the postoperative analgesic effect of a continuous wound infusion of local anesthetics and a sole transverse abdominal plan (TAP) regional block in the surgery of…
- Trial name
- NCT01862354
- Testing
- Transverse abdominal plan block, Continuous wound infusion
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- University of Liege
Hysterectomy, Postoperative Pain
Postoperative Analgesic Effectiveness of the Modified Thoracoabdominal Nerve Block Through a Perichondrial Approach in Total Laparoscopic Hysterectomy
This single-center retrospective cohort study evaluated the effect of the modified thoracoabdominal nerves block through a perichondrial approach (M-TAPA) on postoperative analgesia in patients undergoing elective total…
- Trial name
- MTAPA-TLH (NCT07740252)
- Testing
- Modified thoracoabdominal nerves block through a perichondrial approach (M-TAPA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Namik Kemal University
Analgesia, Inguinal Surgery
"Comparison of USG-Guided Caudal Versus Ilioinguinal/Iliohypogastric Nerve Block for Pediatric Inguinal Surgeries"
This study is designed to compare the analgesic effectiveness of caudal analgesia to ilioinguinal regional analgesia techniques in children undergoing inguinal surgeries.
- Conditions
- Analgesia, Inguinal Surgery, Undescended Testes, Hydrocele
- Trial name
- CAUCIN (NCT05558748)
- Testing
- USG-guided Caudal block, USG-guided Ilioinguinal/Iliohypogastric block
- Where
- Oman
- Volunteers
- 128 people
- Sponsor
- Sultan Qaboos University
Pain, Postoperative, Anesthesia, Local
Postoperative Analgesia in Laparoscopic Abdominal Surgery After Exparel Via TAP or Local Infiltration
This study evaluates differences in how administering liposomal bupivacaine via two different methods affects postoperative pain control in laparoscopic abdominal surgery patients.
- Conditions
- Pain, Postoperative, Anesthesia, Local, Anesthesia; Functional, Anesthesia
- Trial name
- NCT03927326
- Testing
- Exparel 266 MG Per 20 ML Injection
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Washington
Tourniquet Pain, Ischemia-reperfusion
The Effect of Prolonged ischemıa and anesthetıc Agents on Oxidative Stress
The goal of this observational study is to learn about the relationship between postoperative pain and tourniquet-induced oxidative damage in adults undergoing orthopedic knee arthroscopy surgery.The goal of this observational…
- Conditions
- Tourniquet Pain, Ischemia-reperfusion, Postoperative Pain, Anesthesia
- Trial name
- NCT06942650
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duzce University
Analgesia
Comparison of Meperidine and Sufentanil Added to 0.5% Hyperbaric Bupivacaine for Spinal Anesthesia in Cesarean Section
Subarachnoid block is a widely used anesthetic technique for cesarean section. To improve the quality of analgesia and prolong its duration, the addition of intrathecal opioids to local anesthetics has been encouraged.
- Trial name
- NCT04446715
- Testing
- sufentanil, meperidine, Bupivacaine
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Cesarean Delivery, Postoperative Analgesia
Intrathecal Morphine vs Transversalis Fascia Plane Block After Cesarean Delivery
This prospective single-center study compares intrathecal morphine and ultrasound-guided bilateral transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean delivery under spinal…
- Conditions
- Cesarean Delivery, Postoperative Analgesia, Obstetric Anesthesia
- Trial name
- NCT07374133
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ondokuz Mayıs University
Acute Pain, Regional Anesthesia
EOIB for Laparoscopic Sleeve Gastrectomy
n obese patients, adequate pain relief in the postoperative period is a crucial parameter that affects patient comfort and hospital stay.
- Conditions
- Acute Pain, Regional Anesthesia, Morbid Obesity
- Trial name
- NCT07101835
- Testing
- Bilateral ultrasound guided external oblique intercostal block (EOIB), ıv morphine PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ondokuz Mayıs University
Intra-operative Anesthesia and Analgesia Effects
Pediatric Ilioinguinal / Iliohyogogastric Nerve Block
Ilioinguinal / iliohyogogastric nerve blocks; It is frequently used for analgesia and anesthesia in inguinal region surgeons. However, 95% of these surgeons are under general anesthesia.
- Trial name
- NCT02990884
- Testing
- ketamine
- Volunteers
- 60 people
- Sponsor
- Erzincan University
Postoperative Pain
Transversalis Fascia Plane Block Versus Low-Dose Intrathecal Morphine for Open Inguinal Hernia Repair
Open inguinal hernia repair is commonly associated with early postoperative pain, which may delay mobilization, reduce patient satisfaction, and increase opioid consumption.
- Trial name
- NCT07695935
- Testing
- Intrathecal morphine, Ultrasound-guided transversalis fascia plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hitit University
Toothache
The Comparison of Supraperiosteal Nerve Block With Opiate Analgesia in Alleviating the Pain of Toothache
This study will compare the degree of pain control provided by two techniques for persons with toothache in an emergency department.
- Trial name
- NCT00574015
- Testing
- hydrocodone/acetaminophen, bupivacaine (supraperiosteal nerve block)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Albany Medical College
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