Clinical trials: Anesthesia and Analgesia
Inguinal Hernia, Postoperative Pain
Lumbar ESP Block Versus TAP Block for Postoperative Pain Control in Children Undergoing Open Inguinal Hernia Repair
This study evaluates two ultrasound-guided nerve block techniques-Erector Spinae Plane Block (ESPB) and Transversus Abdominis Plane (TAP) block-for pain relief in children undergoing elective open inguinal hernia repair.
- Trial name
- NCT07916233
- Testing
- Ultrasound-guided Lumbar Erector Spinae Plane Block (ESPB), Ultrasound-guided Transversus Abdominis Plane (TAP) Block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Beni-Suef University
Hysterectomy, Postoperative Pain
Postoperative Analgesic Effectiveness of the Modified Thoracoabdominal Nerve Block Through a Perichondrial Approach in Total Laparoscopic Hysterectomy
This single-center retrospective cohort study evaluated the effect of the modified thoracoabdominal nerves block through a perichondrial approach (M-TAPA) on postoperative analgesia in patients undergoing elective total…
- Trial name
- MTAPA-TLH (NCT07740252)
- Testing
- Modified thoracoabdominal nerves block through a perichondrial approach (M-TAPA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Namik Kemal University
Postoperative Pain, Opioid Use
Continuous Serratus Anterior Blockade for Sternotomy
This is a pilot study to assess the feasibility of a full study. The purpose is to assess the analgesic effectiveness of the serratus anterior plane (SAP) block following cardiac surgery.
- Conditions
- Postoperative Pain, Opioid Use, Quality of Life
- Trial name
- Cardiac-SAP (NCT04648774)
- Testing
- Serratus anterior plane (SAP) block
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Maternal Hypotension, Labor Epidural Analgesia
Maternal and Fetal Clinical Significance of Hypotension Following Labor Epidural Analgesia
The goal of this study is to learn how often blood pressure drops after an epidural for labor and how these drops may affect the parent and the baby.
- Conditions
- Maternal Hypotension, Labor Epidural Analgesia, Fetal Heart Rate Abnormalities
- Trial name
- NCT07272018
- Testing
- Epidural Analgesia (Standard Clinical Care)
- Volunteers
- 480 people
- Sponsor
- The Chaim Sheba Medical Center
Hypospadias, Penile Torsion
Caudal vs. Pudendal Block in Peds GU
This study will compare two techniques to minimize pain during and after penile surgery in children undergoing certain urologic surgeries. These two approaches include the caudal nerve block and the pudendal nerve block.
- Conditions
- Hypospadias, Penile Torsion, Chordee, Phimosis
- Trial name
- NCT05708989
- Testing
- Caudal Block, Ultrasound-guided Pudendal Block, Injectable 1 ml/kg of 0.25% ropivacaine with 1mcg/kg dexmedetomidine
- Where
- United States
- Sponsor
- University Hospitals Cleveland Medical Center
Arthroplasty, Replacement, Hip, Fascia Iliaca Block
Ultrasound Guided Fascia Iliaca Block for Pain Control After Elective Hip Replacement Surgery
The purpose of this study is to determine whether ultrasound guided fascia iliaca blocks performed before surgery help to reduce pain after elective total hip replacements.
- Trial name
- NCT02108847
- Testing
- .2% Ropivacaine, Saline, Fascia Iliaca Block
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Saskatchewan
Eventration, Regional Anesthesia
Serratus Intercostal Block Versus Epidural/Port Infiltration Analgesia in Eventration: Prospective Non Inferiority Study
Adequate pain control, rehabilitation and early postoperative recovery are currently the model to follow according to the recommended guidelines.In this project the main objective is to evaluate 2 different analgesic strategies…
- Conditions
- Eventration, Regional Anesthesia, Epidural; Anesthesia, Abdominal Hernia
- Trial name
- Analgesic Stra (NCT06014749)
- Testing
- undergo, ultrasound, Local anesthetic
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Hospital del Rio Hortega
Postoperative Pain
Association of Different Doses of Clonidine in Caudal Epidural Anesthesia for Hypospadias Surgery
The use of increasing doses of clonidine ssociated to bupivacaine in caudal epidural block provides better postoperative analgesia compared whit analgesia provide by bupivacaine alone It is a randomized, double blind study…
- Trial name
- clonidine (NCT02769390)
- Testing
- Clonidine 1 mcg/Kg, Clonidine 2 mcg/ Kg, Clonidine 3 mcg/ Kg
- Volunteers
- 80 people
- Sponsor
- Federal University of Minas Gerais
Pain Management
Opioid-free Anesthesia as an Alternative to General Anesthesia in Patients Undergoing Laparoscopic Peripheral Pancreatic Resection
Opioid-free anesthesia is not associated with greater pain than opioid anesthesia and is associated with reduced postoperative pain.
- Trial name
- OFAPP (NCT07378189)
- Testing
- Opioid Free Anesthesia (OFA), Balanced anesthesia with opioids
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Jagiellonian University
Total Hip Arthroplasty, Analgesia
Spinal Nalbuphine for Analgesia in Total Hip Arthroplasty
60 patients ASA I-III, undergoing total hip arthroplasty were randomly assigned, into one of two groups, namely group E (n=30), where levobupivacaine will be administeral intrathecally ; and group N (n=30), where levobupivacaine…
- Trial name
- NCT06577155
- Testing
- Levobupivacaine, Levobupivacaine plus nalbuphine
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Asklepieion Voulas General Hospital
Pain
Comparison of US-Guided Paravertebral and Proximal Intercostal Nerve Blocks
The purpose of this study is to compare the proximal intercostal block to the more medial (classic) ultrasound-guided paravertebral block.
- Trial name
- NCT02911168
- Testing
- Proximal Intercostal Block, Paravertebral Block
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Postoperative Analgesia, Hip Surgery
PENG vs Deep Iliacus Plane Block in Intertrochanteric Femur Fractures
Intertrochanteric femur fractures are common in elderly patients and are associated with significant pain. Providing effective analgesia is clinically important both during positioning for spinal anesthesia and in the…
- Trial name
- NCT07513740
- Testing
- Intravenous Analgesia, Pericapsular nerve group (PENG) block, Deep Iliacus Plane Block (DIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Erzincan Binali Yildirim Universitesi
Postoperative Pain, Postoperative Complications
Comparison of the Efficacy of Peripheral Nerve Blocks in Major Open Gynaecological Cancer Surgery
The aim of this prospective randomized study was to compare the effectiveness of subcostal transversus abdominis plane block or rectus sheath block applied in addition to posterior transversus abdominis plane block for…
- Conditions
- Postoperative Pain, Postoperative Complications, Analgesia, Regional Anesthesia Morbidity
- Trial name
- NCT06342076
- Testing
- Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block, Patients undergoing rectus sheat block and posterior transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Chest Pain, Pain, Procedural
Evaluation of the Effectiveness of Two Methods of Regional Anesthesia During S-ICD Implantation Procedure.
Our study consists of a combination of regional blockade ('local' anesthesia) of the anterior and lateral chest wall in the form of a thin needle prick and the supply of local anesthetic drugs to the area of the relevant chest…
- Conditions
- Chest Pain, Pain, Procedural, Pain, Postoperative, Analgesia
- Trial name
- NCT06520150
- Testing
- Regional anaesthetic combined fascial plane block, Ropivacaine 0.125% Injectable Solution +Lignocaine 0,25% Injectable Solution
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Pain
Preoperative Ketorolac for Pain Control in Scleral Buckle Surgery
The scleral buckle surgery is an effective way in treating retinal detachment (RD) patients. Retrobulbar block has been proved effective in scleral buckle surgery.
- Trial name
- NCT02729285
- Testing
- Ketorolac Tromethamine, scleral buckle
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Sun Yat-sen University
Anesthesia, Obstetrical, Analgesia, Epidural
Epidural Analgesia During Labour
Randomized single blind trial based on comparing the way the local anesthetic is dosificated during labour. The pain control is evaluated and compared with both dosage techniques (PCEA vs PIEB)using levobupivacaine and fentanyl.
- Trial name
- PIEBvsPCEA (NCT03133091)
- Testing
- PIEB: Patient Intermittent Epidural Boluses, PCEA: Patient Controlled Epidural Analgesia
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital del Rio Hortega
Postoperative Pain, Shoulder Surgeries Operations
Interscalene Versus Costoclavicular Blocks for Shoulder Surgery
AIM: Shoulder surgeries are among the most painful surgical procedures in orthopedic practice. Interscalene brachial plexus block, although the most commonly utilized regional anesthesia technique for alleviating pain following…
- Conditions
- Postoperative Pain, Shoulder Surgeries Operations, Regional Anesthesia, Costoclavicular Block
- Trial name
- NCT06953947
- Testing
- Costoclavicular block, Interscalene block, Interscalene Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Sakarya University
Pain, Postoperative
Exparel vs. Standard Bupivicaine for Abdominoplasty
Background \& study question: Strategies for post-operative pain control that make use of various different types of medicines are advantageous both for patient comfort and for minimizing the use of opioid pain medicines and…
- Trial name
- NCT01853176
- Testing
- Liposomal Injection Bupivacaine (Exparel), Standard bupivicaine
- Where
- 3 sites in United States
- Volunteers
- 4 people
- Sponsor
- Emory University
Nerve Block, Coronary Artery Bypass
Comparison of Erector Spinae Plane Block and Transversus Thoracic Muscle Plane Block in Coronary Artery Surgery
The main objective of this study is to evaluate postoperative pain intensity comparatively between erector spinae plane block and transversus thoracic muscle plane block in patients undergoing open coronary artery surgery.
- Conditions
- Nerve Block, Coronary Artery Bypass, Anesthesia and Analgesia
- Trial name
- NCT06709625
- Testing
- Transversus thoracis plane block, Erector spina plane block (ESP)
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Ankara City Hospital Bilkent
Ankle Sprain, Ankle (Ligaments); Instability (Old Injury)
Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy
Ankle arthroscopy is increasingly performed as a day-case procedure, making rapid recovery and efficient discharge critical. Anesthetic technique substantially influences postoperative recovery, yet high-quality evidence…
- Conditions
- Ankle Sprain, Ankle (Ligaments); Instability (Old Injury), Pain Management, ERAS
- Trial name
- NCT07460310
- Testing
- Total intravenous anesthesia combined with peripheral nerve block (TIVA + PNB) group, General anesthesia combined with peripheral nerve block (GA + PNB) group, Spinal anesthesia
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.