Clinical trials: Anesthesia for Cesarean Delivery
Cesarean Section Complications
Perfusion Index and Pleth Variability Index in Cesarean Section.
The aim of this study is to investigate the predictability of hypotension by using PI and PVI in pre-and post-spinal anesthesia periods in cesarean section cases in the sitting position.
- Trial name
- NCT04195087
- Testing
- Masimo Radical-7® Pulse CO-Oximeter®
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Antalya Training and Research Hospital
Maternal Hypotension After Spinal Anesthesia
Height Versus Height and Weight Based Spinal Bupivacaine on Maternal Haemodynamics for Elective Cesarean in Short Stature Patients
Doses of intrathecal bupivacaine based on patients either height or height and weight has shown to lower the risk of maternal hypotension with similar quality of anesthesia compared to conventional doses.
- Trial name
- NCT04082676
- Testing
- Hyperbaric bupivacaine spinal
- Where
- Nepal
- Volunteers
- 112 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Pain, Postoperative, Postoperative Nausea and Vomiting
Dexamethasone for Post-cesarean Delivery Pain
The purpose of this study is to compare post-cesarean section consumption of pain medication between two groups of patients undergoing scheduled cesarean section at term gestation who receive a single-dose of intraoperative…
- Trial name
- NCT01812057
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Duke University
Smoking Cigarette, Spinal Anaesthesia
Does Smoking Effect Spinal Anesthesia?
Background In the last 10 years, the rate of smoking in women of childbearing age has increased gradually. The smoking affects general anesthesia negatively.
- Conditions
- Smoking Cigarette, Spinal Anaesthesia, Pregnancy, Cesarean Section
- Trial name
- NCT05343845
- Testing
- Observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Hypotension (MeSH: D007022), Bradycardia
Prophylactic Ondansetron and Maternal Hemodynamics During Spinal Anesthesia for Elective Cesarean Section
Spinal anesthesia is the preferred technique for elective cesarean section, but it is frequently complicated by maternal hypotension and bradycardia.
- Trial name
- NCT07883772
- Testing
- Ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Aydin Adnan Menderes University
Hypotension After Spinal Anesthesia, Hypotension During Cesarean Delivery
Ephedrine Doses to Prevent Maternal Hypotension After Spinal Anesthesia in Cesarean Section
This randomized controlled trial aims to compare the effectiveness of different doses of ephedrine infusion in preventing maternal hypotension following spinal anesthesia in parturients undergoing cesarean sections.
- Trial name
- NCT06668337
- Testing
- Ephedrine
- Where
- Nepal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Cesarean Section Complications, Spinal Anesthesia
Three Protocols for Phenylephrine Administration in Cesarean Delivery
The investigators will compare variable infusion of phenylephrine (at a starting rate of 0.75 mcg/Kg/min) with fixed rate (0.75 mcg/Kg/min which will stop of reactive hypertension occurred) and single shot (1.5 mcg/Kg)…
- Trial name
- NCT03302039
- Testing
- Single shot phenylephrine, Fixed infusion phenylephrine., Variable infusion phenylephrine.
- Where
- Egypt
- Volunteers
- 217 people
- Sponsor
- Cairo University
Pain, Obesity
Effect of Body Mass Index on the Dose of Intrathecal Hyperbaric Bupivacaine for Elective Cesarean Section
Combined spinal - epidural (CSE) anesthesia is a well established technique used for elective Cesarean section. As its name suggests, it combines two anesthesia techniques - spinal and epidural.
- Trial name
- NCT00403663
- Testing
- bupivacaine 0.75% with fentanyl and morphine
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Preeclampsia
ST- Depression on Electrocardiogram During Caesarean Section in Regional Anaesthesia in Women With Preeclampsia
The investigators examined whether there was a difference in the occurrence of ST depressions after injection of five or ten units of oxytocin, in preeclamptic patients delivered by caesarean section (CS) under regional…
- Trial name
- NCT01530230
- Testing
- oxytocin
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Uppsala University Hospital
Anesthesia, Obestetric
Regional Anesthesia of Cesarean Section
Beta trace protein assay is an indicator of post-spinal CSF leak that predicts the degree of post-spinal headache.
- Trial name
- NCT03556267
- Testing
- spinal needle
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pregnancy, Cesarean Delivery
Sublingual Misoprostol & Isoflurane During Caesarean Section
Misoprostol would reduce the uterine bleeding after caesarean delivery, without harmful effects on either mother or baby. The investigators postulated that the use of sublingual misoprostol during isoflurane anaesthesia for…
- Trial name
- NCT01466530
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 366 people
- Sponsor
- Mansoura University
Cesarean Section, Postoperative Nausea and Vomiting (PONV)
Restrictive vs Liberal Intraoperative Fluid Strategy and Postoperative Outcomes After Elective Cesarean Section
Spinal anesthesia for elective cesarean section is frequently associated with hemodynamic instability and postoperative complications such as postoperative nausea and vomiting (PONV) and delayed gastrointestinal recovery.
- Conditions
- Cesarean Section, Postoperative Nausea and Vomiting (PONV), Postdural Puncture Headache (PDPH), Postoperative Ileus
- Trial name
- NCT07440667
- Testing
- Restrictive intraoperative crystalloid fluid strategy (≤3 mL/kg/h), Liberal intraoperative crystalloid fluid strategy (>3 mL/kg/h)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Nigde Omer Halisdemir University
Adverse Effect
Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension
The purpose of this study is to investigate the suitable infusion dose of norepinephrine for prophylaxis against post-spinal anesthesia hypotension.
- Trial name
- NCT04272567
- Testing
- Norepinephrine, Normal saline
- Where
- China
- Volunteers
- 99 people
- Sponsor
- General Hospital of Ningxia Medical University
Cesarean Delivery; Neuraxial Opioids
Respiratory Rate After Cesarean Delivery
The study proposal summarizes aspects related to respiratory rate in women who undergo spinal anesthesia for cesarean delivery who receive or do not receive neuraxial opioids
- Trial name
- NCT04250233
- Testing
- Respiratory Monitor
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Postoperative Pain, Cesarean Section
Comparison of the Time to the First Rescue Analgesic Among Parturients Receiving Intrathecal Additive Fentanyl or Intrathecal Fentanyl With TAP Block or TAP Block Alone for Elective Cesarean Sections Under Hyperbaric Bupivacaine Spinal Anesthesia
The postoperative pain management after cesarean section under spinal anestheisa is done using various modalities. The commonly used regimens are systemic NSAIDs/Opioids, USG guided TAP block or Intrathecal additive Fentanyl or…
- Trial name
- NCT05550597
- Testing
- Fentanyl HCl, Bupivacaine 0.25% Injectable Solution
- Where
- Nepal
- Volunteers
- 93 people
- Sponsor
- Nepal Mediciti Hospital
Cesarean Section
TAP Block With Intrathecal Fentanyl vs. Intrathecal Morphine in Cesarean Delivery
This noninferiority study aims to determine whether transversus abdominis plane (TAP) block with intrathecal fentanyl could provide a noninferior analgesia compared with intrathecal morphine after cesarean delivery under spinal…
- Trial name
- NCT04824274
- Testing
- fentanyl, morphine, Transversus abdominis plane block
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Elective Cesarean Section, Preeclampsia
Ultrasonography for Fluid Assessment in Parturients With Preeclampsia Undergoing Cesarean Section
Preeclampsia is a multifocal syndrome reported in 2-8 % of pregnancies. It is diagnosed in the second half of pregnancy by two separate measurements of systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥ 90 mmHg…
- Trial name
- NCT04370847
- Testing
- Spinal Anesthesia, Intrathecal Bupivacaine, Intrathecal Fentanyl
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Itching
Effect of Slow Injection of Fentanyl on the Incidence of Spinal Anesthesia Induced Itching in Cesarean Section
Pruritus is a troublesome side-effect of neuraxial (epidural and intrathecal) opioids. Sometimes it may be more unpleasant than pain itself.
- Trial name
- NCT02951806
- Testing
- (R) Rapid spinal fentanyl injection, (S) Slow spinal fentanyl injection
- Volunteers
- 215 people
- Sponsor
- Dr. Soliman Fakeeh Hospital
Shivering, Labor
Investigating the Effect of Acupressure on Shivering During a Cesarean Delivery in Women Who Were Previously Laboring With an Epidural
Shivering during a cesarean section can be quite uncomfortable for the patient as well as make it difficult for the anesthesiologist to obtain vital signs.
- Conditions
- Shivering, Labor, Cesarean Delivery
- Trial name
- NCT03497507
- Testing
- Acupressure bracelet
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Adverse Effect
Different Crystalloid Coload Volumes on the 90% ED of Norepinephrine
The purpose of this study is to investigate the effect of different crystalloid coload volumes on the 90% effective dose of prophylactic norepinephrine infusions for preventing postspinal anesthesia hypotension during cesarean…
- Trial name
- NCT05690334
- Testing
- Crystalloid - 0 ml/kg, Crystalloid - 5 ml/kg, Crystalloid - 10 ml/kg
- Where
- China
- Volunteers
- 90 people
- Sponsor
- General Hospital of Ningxia Medical University