Clinical trials: Anesthesia for Cesarean Delivery
Obese, Cesarean Section
Conventional Palpation Versus Ultrasound Assisted Spinal Anesthesia in Obstetrics
Spinal anesthesia in obese parturients is commonly difficult yet there are no guidelines to direct best practice. The failure leads to suboptimal patient outcomes.
- Conditions
- Obese, Cesarean Section, Anesthesia Spinal
- Trial name
- NCT05846100
- Testing
- Preprocedural spinal ultrasound, fictional preprocedure spinal ultrasound
- Where
- Tunisia
- Volunteers
- 90 people
- Sponsor
- Mongi Slim Hospital
Pain, Postoperative
Intrathecal Additives for Spinal Anaesthesia in Elective Caesarean Sections
we designed this randomized, single -blind, prospective clinical study to test postoperative analgesia of three intrathecal additives in elective caesarean sections which are magnesium, dexamethasone and dexmedetomidine.
- Trial name
- NCT04747171
- Testing
- intrathecal Magnesium, intrathecal dexamthasone, intrathecal dexmedetomidine
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Benha University
Pregnancy Related
Different Anesthesia Methods on Development of Postnatal Depression After Cesarean Delivery
Childbirth is one of the most painful experiences for a woman. Labor and period of pregnancy is associated with an increased risk of psychiatric disorders for a woman.
- Trial name
- NCT04565730
- Testing
- Grup I= General anesthesia group, Grup II= Spinal anesthesia group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Medipol University
Hypotension, Spinal Anesthesia
Norepinephrine or Phenylephrine in Bolus for Hypotension in Cesarean Delivery
This study evaluate the ability of phenylephrine and of noradrenaline to maintain normal systemic arterial blood pressure and heart rate in healthy pregnant women submitted to cesarean section with spinal anesthesia.
- Trial name
- NCT03702400
- Testing
- Phenylephrine 100 mcg, Norepinephrine 5 mcg
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospital dos Servidores do Estado do Rio de Janeiro
Gestational Diabetes Mellitus (GDM), Obstetric Anesthesia
ULTRASOUND ASSESSMENT OF GASTRİC VOLUME IN PREGNANT WOMEN UNDERGOİNG ELECTİVE CESAREAN SECTİON, WITH AND WITHOUT GESTATİONAL DIABETES MELLITUS
THE PRIMARY OBJECTIVE OF THIS STUDY IS TO COMPARE GASTRIC VOLUME PRIOR TO ELECTIVE CESAREAN SECTION BETWEEN PREGNANT WOMEN DIAGNOSED WITH GESTATIONAL DIABETES MELLITUS (GDM) AND THOSE WITHOUT GDM.
- Trial name
- GDM (NCT07816705)
- Testing
- GASTRIC ULTRASONOGRAPHY
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
Epidural Anesthesia
Efficacy and Safety of Electric Stimulation-guided Epidural Anesthesia for Cesarean Section
Forty pregnant women (36 to 41 weeks gestation) will randomly allocate to two groups. Groups will be defined based on the method used to identify the epidural space for epidural anesthesia: the loss of resistance group (n=20) and…
- Trial name
- NCT03443466
- Testing
- Epidural electrical stimulation (EES), Loss of resistance (LOR)
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Korea University Guro Hospital
Cesarean Section Complications, Cesarean Section Pain
Insufficient Regional Anesthesia and Conversion to General Anesthesia for Cesarean Section A Qualitative Multicenter Study
Background In Denmark, approximately 20% of all children are born via cesarean section (C-section), making it the most common surgical procedure (also internationally).
- Conditions
- Cesarean Section Complications, Cesarean Section Pain, Regional Anesthesia
- Trial name
- NCT06669156
- Where
- 7 sites in Denmark
- Volunteers
- 21 people
- Sponsor
- Sygehus Lillebaelt
Blood Pressure Measurement
Agreement of the Nexfin™ Monitor With Non-invasive Blood Pressure Measurement
Currently, BP is measured using an inflatable cuff wrapped around the patient's upper arm. This can be set to inflate every minute, but measurement may fail due to patient movement or shivering.
- Trial name
- Nexfin Pilot (NCT02447471)
- Testing
- Nexfin
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Postanesthetic Excitement, Cesarean Section
Dexmedetomidine Compared to Ondansetron for Postanaesthetic Shivering in Patients Undergoing a Cesarean Section
Evaluate the efficiency of management with intravenous dexmedetomidine compared to intravenous ondansetron to achieve the disappearance of post-anesthetic shivering in a shorter time in the obstetric patient undergoing cesarean…
- Trial name
- NCT06289335
- Testing
- saline solution
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital Central "Dr. Ignacio Morones Prieto"
Hypotension, Cesarean Section
"Effect of Pre-Spinal Mindfulness-Based Breathing Exercise on Hemodynamic Response in Elective Cesarean Section"
Spinal anesthesia-induced hypotension is one of the most frequent and clinically significant complications of obstetric anesthesia, occurring in up to 50-80% of parturients undergoing elective cesarean section.
- Conditions
- Hypotension, Cesarean Section, Hemodynamic Instability, Anxiety, Anticipatory
- Trial name
- BREATHE-CS (NCT07494955)
- Testing
- Mindfulness-Based Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Aysenur Dostbil
Elective Cesarean Section, Spinal Anesthesia
Effect of Different Left Lateral Table Tilt for Elective Cesarean Delivery Under Spinal Anesthesia
The recommended position of the mother under caesarean section after spinal anesthesia is 15 degrees left. However, recent research has challenged the basic principles and practicality of the left-turn 15 degree position.
- Trial name
- NCT04083768
- Testing
- 15° and 30° wedge sponges
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Xuzhou Medical University
Regional Anaesthesia in Cesarean Operations
Comparison of Dural Puncture Epidural and Standard Epidural Anesthesia Techniques in Elective Cesarean Deliveries
Neuraxial techniques are the most effective form of labor analgesia in contemporary obstetric anesthesia practice, predominantly through the use of epidural (EPL) and combined spinal-epidural (CSE) techniques.
- Trial name
- NCT07295080
- Testing
- Dural puncture epidural (DPE) anaesthesia, standart epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Post-spinal Hypotension
Variability of Perfusion Index to Predict Hypotension
About one-third of deliveries are performed by cesarean section, and this rate is increasing. The standard anesthetic technique for this procedure is spinal anesthesia (SA), which is associated with hypotension in nearly 70% of…
- Trial name
- IP-HYPO (NCT06769750)
- Testing
- leg-lift maneuver
- Where
- 2 sites in France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia
Comparison of 3 Different Density Levobupivacaine Solutions + Fentanyl for Spinal Anaesthesia for Caesarean Delivery.
The investigator's aim is to compare the efficacy of 3 levobupivacaine solutions with different density on spinal anesthesia for caesarean delivery.
- Trial name
- NCT03956303
- Testing
- Chirocaine %0.5, Chirocaine Heavy 40, Chirocaine Heavy 60
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Caesarean Section
The Pleth Variability Index and Hypotension at Caesarean Under Spinal.
During a caesarean section the blood pressure is usually measured every few minutes and it may fall too quickly to be detected in a timely fashion by this intermittent means.
- Trial name
- NCT02285569
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Preeclampsia, Spinal Anesthesia-Induced Hypotension
Dexamethasone Versus Ondansetron for Preventing Post-Spinal Hypotension in Preeclampsia
This study compares the efficacy and safety of intravenous dexamethasone versus intravenous ondansetron in preventing low blood pressure (hypotension) following spinal anesthesia in pregnant women with preeclampsia undergoing…
- Conditions
- Preeclampsia, Spinal Anesthesia-Induced Hypotension, Cesarean Section
- Trial name
- NCT07793760
- Testing
- Dexamethasone, Ondansetron
- Volunteers
- 110 people
- Sponsor
- Assiut University
Anesthesia, Spinal, Cesarean Section
Combined Colloid Preload And Crystalloid Coload Versus Crystalloid Coload During Spinal Anesthesia for Cesarean Delivery
The study will compare one technique of fluid administration (combined colloid preload and crystalloid colaod) with another one (crystalloid coload) during elective cesarean delivery performed under spinal anesthesia.
- Trial name
- NCT02961842
- Testing
- 500 mL Colloid Preload, Spinal Anesthesia, Intrathecal Bupivacaine
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mansoura University
Anesthesia
Magnesium for Shivering in Epidural Lidocaine Deliveries
Magnesium has been shown to decrease the shivering experienced from neuraxial anesthesia. This study aims to investigate whether magnesium decreases the shivering experienced in parturients undergoing labor epidural anesthesia…
- Trial name
- Mag-SHIELD (NCT03439358)
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Spinal Hypotension, Doppler
Doppler Indices to Predict Spinal Hypotension During Cesarean Section
Spinal anesthesia is safe and advisable anesthetic during cesarean section, despite that spinal induced hypotension is a common associated problem.
- Trial name
- NCT06825806
- Testing
- Femoral artery Doppler
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cesarean Section Complications
Vasopressor Prophylaxis After Spinal Anesthesia
Norepinephrine has been recently introduced as a prophylactic vasopressor during Cesarean delivery with promising results ; However, the optimum dose for efficient prophylaxis with the least side effects is not known.
- Trial name
- NCT03234816
- Testing
- Norepinephrine 0.05 mcg /Kg/min, Norepinephrine 0.1 mcg /Kg/min, Norepinephrine 0.15 mcg /Kg/min
- Where
- Egypt
- Volunteers
- 270 people
- Sponsor
- Cairo University