Clinical trials: Anesthesia for Cesarean Delivery
Cesarean Section Complications, Spinal Anesthetic Toxicity
Comparison of Two Norepinephrine Bolus Doses for Management of Post-spinal Hypotension During Cesarean Delivery
In this study the investigators will compare two doses of norepinephrine bolus (6 mcg and 10 mcg) in management of maternal hypotensive episode after subarachnoid block during Cesarean delivery.
- Trial name
- NCT03792906
- Testing
- Norepinephrine 6 mcg, Norepinephrine 10 mcg, Norepinephrine infusion
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Cairo University
Cesarean Delivery
An Observational Study Measuring in a Non-invasive Approach the Nociception Level Index and Its Association With Pain and Anxieiy Perception Evaluated by Questionnaires, in Awake Women During Elective Cesarean Delivery Under Spinal Anesthesiaanxiety
The Nociception Level (NOL) Index is a multiparametric, non-invasive monitor that objectively assesses nociception by integrating several autonomic physiological signals.
- Trial name
- NCT07726316
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Michael Grach
Anesthesia, General, Anesthesia, Spinal
The Effect of General and Spinal Anesthesia on Neutrophil-to-lymphocyte Ratio
The aim of the study was to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV)…
- Conditions
- Anesthesia, General, Anesthesia, Spinal, Umbilical Cord
- Trial name
- NCT05409885
- Testing
- General anesthesia, Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Spinal Anesthesia, Hypotension
Prediction of Spinal Anesthesia-Induced Hypotension in Cesarian Section: Carotid Artery-Corrected Flow Time Versus Cardiometry
This research aimed to evaluate and compare the role of carotid corrected flow time (FTc) and electrical cardiometry (EC) in the prediction and prevention of post-spinal hypotension in elective cesarian section.
- Conditions
- Spinal Anesthesia, Hypotension, Cesarian Section, Carotid Artery
- Trial name
- NCT06236217
- Testing
- Carotid Ultrasound, Electrical cardiometry
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Tanta University
Spinal Anesthesia
Measuring Cerebrospinal Fluid (CSF) Glucose Levels in Patients Under Going an Elective Cesarean Section With Spinal Anesthesia
This study will determine the level of glucose (sugar) in the CSF (fluid that surrounds the spinal cord) in 30 subjects having spinal anesthesia for cesarean section using a bedside glucose meter.
- Trial name
- NCT01067560
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anesthesia
Peripheral Skin Temperature Changes Following Spinal Anaesthesia for Category 4 LSCS
Regional anaesthesia of the lower limbs blocks sympathetic nerve fibres as well as sensory and motor fibres. It has been documented previously in the non-pregnant population that the blockade of sympathetic nerve fibres by…
- Trial name
- NCT05726760
- Testing
- Seeking informed consent for participation in the study., Temperature measurement by Braun Welch Allyn tympanic membrane thermometer device to the dorsum of the right and left feet above space between the 2nd and 3rd metatarsal bones., Covidien Mon-a-Therm skin temperature probes will be applied to the dorsum of the right and left feet above space between the 2nd and 3rd metatarsal bones.
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Spinal Anesthesia
Large Volume Bupivacaine 0.5% Versus Small Volume in Elective Caesarean Section
To test the safety of high dose spinal in elective CS after prolonged sitting position.
- Trial name
- NCT02937792
- Testing
- intrathecal 15 mg bupivacaine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Parturients, Elective Cesarean Delivery
Maternal Satisfaction After Spinal Anesthesia for Cesarean Delivery
The goal of this observational study is to evaluate the impact of four different spinal anesthesia regimens on maternal satisfaction following cesarean delivery.
- Trial name
- NCT07438171
- Testing
- Bupivacaine %0.5 (hyperbaric), Bupivacaine %0.5 (hyperbaric) and morphine, Bupivacaine %0.5 (hyperbaric), morphine and fentanyl 15
- Volunteers
- 200 people
- Sponsor
- University of Novi Sad
Healthy
Dexamethasone Intravenous Versus Intrathecal in Spinal Anesthesia
The purpose of this study is to compare the the effect of intravenous and the intrathecal dexamethasone when added to spinal anesthesia in cesarean section.
- Trial name
- NCT05470530
- Testing
- Dexamethasone
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cesarean Section, Postoperative Pain After Cesarean Section
Predictors of Severe Postoperative Pain Within 24 Hours After Elective Cesarean Delivery Under Spinal Anesthesia
This prospective observational study aims to identify predictors of severe postoperative pain during the first 24 hours after elective cesarean delivery under spinal anesthesia.
- Conditions
- Cesarean Section, Postoperative Pain After Cesarean Section, Acute Pain
- Trial name
- CS-PAIN24 (NCT07789301)
- Testing
- Observational Assessment of Postoperative Pain
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bursa City Hospital
Cesarean Section, Spinal Anesthesia
Predictability of ANI (Analgesia Nociception Index) for Spinal Hypotension
Spinal anesthesia is widely accepted as the anesthetic method of choice for Cesarean section. However, the incidence of spinal hypotension is 50-70%, and the decrease in blood pressure is often rapid and severe.
- Trial name
- NCT06327165
- Testing
- observation
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Caesarean Section
Ropivacaine 0.75% Versus Levobupivacaine 0.5% for Conversion of Labour Epidural
The aim of this trial is to compare the local anaesthetic ropivacaine to local anaesthetic levobupivacaine in converting the standard patient controlled labour epidural to provide anaesthesia for an emergency Caesarean section.
- Trial name
- RoLe (NCT01160965)
- Testing
- 0.5% levobupivacaine, 0.75% Ropivacaine
- Where
- United Kingdom
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Anesthesia, Analgesia
The Efficacy and Safety of S-ketamine in Elective Cesarean Section
During the past years, a large number of clinical trials have investigated the use of the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist racemic ketamine as an adjunct to local anaesthetics, opioids, or other…
- Conditions
- Anesthesia, Analgesia, Depression, Cesarean Section
- Trial name
- ES-CS (NCT04657107)
- Testing
- S-ketamine, normal saline
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Beijing Obstetrics and Gynecology Hospital
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Leg Elevation for Prevention of Post Spinal Hypotension in Cesarean Section
Prospective trial including full term parturients scheduled for a cesarean section under spinal anesthesia. patients are being randomly assigned into 2 groups: LE group: will be positioned in 15° left tilt with leg elevation with…
- Trial name
- NCT03488277
- Testing
- leg elevation
- Where
- Tunisia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Cesarean Sections
Thoracic vs Lumbar Spinal Anesthesia for Cesarean Delivery
This randomized controlled trial aims to compare the effects of thoracic segmental spinal anesthesia and conventional lumbar spinal anesthesia on postoperative recovery in patients undergoing elective cesarean section.
- Trial name
- NCT07567612
- Testing
- Thoracic Segmental Spinal Anesthesia, Lumbar Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Adiyaman University Research Hospital
Cesarean Delivery Affecting Newborn
Cerebral and Renal Oxymetry and Anesthetic Techniques in Newborns
Neonatal adaptation to extrauterine life has many physiological changes in neonatal organ systems. These adaptative changes may be affected such as type of delivery and anesthesia management at birth.
- Trial name
- NCT03389139
- Testing
- Near infrared spectroscopy (spinal anesthesia), Near infrared spectroscopy (general anesthesia)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Obstetric Anesthesia, Spinal Anesthesia
ED50 Determination of Hydroxyethylstarch for Treatment of Hypotension During Cesarean Section Under Spinal Anesthesia
The purpose of this trial is to determine the effective volume of hydroxyethylstarch 130/0.4 which would prevent the occurence of maternal hypotension in 50% of healthy pregnant women undergoing a cesarean section under spinal…
- Conditions
- Obstetric Anesthesia, Spinal Anesthesia, Hypotension, Fluid Therapy
- Trial name
- NCT01415284
- Testing
- Hydroxyethylstarch 130/0.4
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Cardiac Arrythmias
Carbetocin on Myocardial Repolarization Dynamics in Obstetrics Study
Relationship between carbetocin dose on transmural dispersion of repolarization (TDR).
- Trial name
- CaRDIO (NCT03716076)
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Anesthesia
How Fast Are we? Speed of General Versus Spinal Anesthesia for Emergency Cesarean Delivery: A Simulation Based Study
The researchers wish to undertake a simulation based study to compare the speed of general versus spinal anesthesia for emergency cesarean delivery. Minutes may matter for the baby in an emergency.
- Trial name
- NCT00966680
- Testing
- Anesthesia
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Spinal Anesthesia, Post Operative Analgesia
Dexamethasone in Prolonging the Duration of Spinal Anesthesia Among Pregnant Patients
Lower segment C section is one of the most commonly performed surgeries worldwide. It is performed in spinal anesthesia. During Spinal Anesthesia a local anesthetic drug is administered in a space surrounding spinal cord and it…
- Trial name
- NCT07088146
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College