Clinical trials: Anesthesia for Cesarean Delivery
Adverse Effect
Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia
The purpose of this study is to investigate the efficacy and safety of norepinephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
- Trial name
- NCT04556357
- Testing
- Phenylephrine, Norepinephrine
- Where
- China
- Volunteers
- 138 people
- Sponsor
- General Hospital of Ningxia Medical University
Analgesia, Analgesics, Opioid
Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study
The proposed pilot study is a prospective, randomized, controlled, double-blind, single-center pilot study.The aim of this pilot project is to evaluate the feasibility of a phase III study on the use of dexmedetomidine in…
- Conditions
- Analgesia, Analgesics, Opioid, Anesthesia, Obstetrical, Anesthesia, Spinal
- Trial name
- NCT05099055
- Testing
- Dexmedetomidine 0.004 MG/ML [Precedex], Opioids
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- St. Justine's Hospital
Regional Anaesthesia in Cesarean Operations
Comparison of Dural Puncture Epidural and Standard Epidural Anesthesia Techniques in Elective Cesarean Deliveries
Neuraxial techniques are the most effective form of labor analgesia in contemporary obstetric anesthesia practice, predominantly through the use of epidural (EPL) and combined spinal-epidural (CSE) techniques.
- Trial name
- NCT07295080
- Testing
- Dural puncture epidural (DPE) anaesthesia, standart epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Spinal Anesthesia-Induced Hypotension, Preeclampsia
Investigation of the Role of Internal Jugular Vein Collapsibility Index in Predicting Spinal Anesthesia-Induced Hypotension in Preeclamptic Parturients
This prospective, single-center observational study aims to evaluate the predictive value of the internal jugular vein collapsibility index (IJVCI) for spinal anesthesia-associated hypotension in preeclamptic parturients…
- Conditions
- Spinal Anesthesia-Induced Hypotension, Preeclampsia, Cesarean Section
- Trial name
- NCT07496788
- Testing
- Internal Jugular Vein Collapsibility Index Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ankara City Hospital Bilkent
Neonatal Hypoxia and Asphyxia
Can Shorter Time Intervals Help the Baby Survive the Triad Effect of Maternal Hypertension, Caesarean Section and Spinal Anesthesia?
Patients were classified into two equal groups using the presence or absence of hypertension during pregnancy into: hypertensive group (BP>140/90) and normotensive group (BP≤140/90.
- Trial name
- NCT03461913
- Testing
- Cesarean section
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Pregnancy Related, Anesthesia
Pre-oxygenation With High-flow Nasal Cannula in Caesarian Section Under General Anesthesia
The investigators and other groups have demonstrated that high-flow nasal oxygen used during preoxygenation for emergency surgery is at least equally effective as preoxygenation compared to standard tight fitting mask.
- Conditions
- Pregnancy Related, Anesthesia, Oxygen Deficiency, Cesarean Section Complications
- Trial name
- PRIOROB (NCT04711317)
- Testing
- Nasal high flow oxygen
- Where
- 4 sites in Sweden
- Volunteers
- 34 people
- Sponsor
- Karolinska University Hospital
Hypotension
Spinal Anesthesia Induced Hypotension During Cesarean Section
The purpose of this study is to compare two methods for preventing low blood pressure associated with spinal anesthesia during Cesarean sections.
- Trial name
- NCT00846651
- Testing
- Colloid administration, Crystalloid administration, phenylephrine infusion
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Milton S. Hershey Medical Center
Postspinal Shivering
Intravenous Granisetron Vs Dexmedetomidine on Postspinal in the Cesarean Section.
The Aim of this study is to investigate and compare the efficacy of intravenous Dexmedetomidine (0.3 ug/kg) versus intravenous Granisetron (3 mg) in the prevention of shivering in parturient undergoing cesarean section under…
- Trial name
- NCT06762860
- Testing
- Dexmedetomidine, Granisetron
- Where
- Egypt
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Minia University
Spinal Anesthesia
Measuring Cerebrospinal Fluid (CSF) Glucose Levels in Patients Under Going an Elective Cesarean Section With Spinal Anesthesia
This study will determine the level of glucose (sugar) in the CSF (fluid that surrounds the spinal cord) in 30 subjects having spinal anesthesia for cesarean section using a bedside glucose meter.
- Trial name
- NCT01067560
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cesarean Delivery, Regional Anesthesia Block
TAP Block Versus ESP Block in Patients Undergoing Elective Cesarean Section: a Randomized Controlled Trial
This study is comparing two types of pain relief techniques-TAP block and ESP block-for women having an elective cesarean section.
- Trial name
- NCT07292662
- Testing
- TAP block, ESP block
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- University of Padova
Hypotension
The Effect of Intravenous Prehydration on the Hemodynamic Status of Healthy Parturients Undergoing Spinal Anesthesia for Cesarean Delivery
Regional anesthesia (spinal, epidural) is considered the method of choice for anesthesia obstetric deliveries because of the ability to use fewer drugs, a more direct experience of childbirth and the capability to provide…
- Trial name
- NCT01835873
- Testing
- Lactated Ringer's, HES 130/0.42
- Where
- Greece
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Paraskevi Matsota
Spinal Anesthetic Toxicity, Hypotension Drug-Induced
Comparison of Two Different Norepinephrine Bolus Doses for Management of Spinal Anesthesia-Induced Maternal Hypotension
In this study the investigators will compare two doses of norepinephrine bolus (6 mcg and 8 mcg) in management of maternal hypotensive episode after spinal block during cesarean delivery.
- Conditions
- Spinal Anesthetic Toxicity, Hypotension Drug-Induced, Cesarean Section Complications
- Trial name
- NCT05502146
- Testing
- Noradrenaline Bitartrate, Bupivacaine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mersin University
Anesthesia, Postoperative Pain
Intrathecal Morphine vs. US-Guided Bilateral Posterior Quadratus Lumborum Block in Cesarean Section
In this study, it was aimed to evaluate the effects of intrathecal morphine and posterior quadratus lumborum block (QLB2) on postoperative acute pain scores and opioid consumption in the first 24 hours after cesarean section.
- Trial name
- NCT06481462
- Testing
- Intrathecal Morphine (ITM), Quadratus Lumborum II (QLB-II) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ondokuz Mayıs University
Shivering, Post-Spinal Shivering
Efficacy of Intravenous Midazolam-Ketamine Combination Versus Placebo for Prevention of Post-Spinal Shivering in Elective Cesarean Section
Spinal anesthesia is the preferred anesthetic method for elective cesarean deliveries, but it frequently causes post-spinal shivering.
- Conditions
- Shivering, Post-Spinal Shivering, Hypothermia, Cesarean Section
- Trial name
- NCT07855523
- Testing
- Midazolam and Ketamine, 0.9% Sodium Chloride
- Volunteers
- 120 people
- Sponsor
- Assiut University
Spinal Anesthesia, Pregnancy
Ephedrine vs Phenylephrine - ECG Changes
ECG changes during caesarean section are common. Incidence of ST depression on the ECG is up to 81% in some studies. Although this may indicate inadequate oxygen supply to the heart muscle (myocardial ischaemia) many other…
- Trial name
- NCT01243970
- Testing
- Phenylephrine, Ephedrine
- Where
- United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University College London Hospitals
Anesthesia, Postoperative Pain
Lateral QL Block vs Intrathecal Morphine for Cesarean Section
Effective postoperative analgesia after cesarean delivery is essential for maternal recovery, early mobilization, breastfeeding, and maternal-infant bonding.
- Conditions
- Anesthesia, Postoperative Pain, Regional Anesthesia
- Trial name
- NCT07712783
- Testing
- Lateral Quadratus Lumborum Block, ıv morphine PCA, Intrathecal morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ondokuz Mayıs University
Pregnancy, Cesarean Section, Spinal Anesthesia
The Effectiveness of Binaural Beats on Midazolam Requirement During Cesarean Section With Spinal Anesthesia
Spinal anesthesia is preferred for cesarean section in many institutions due to concerns regarding the potential effects of general anesthetic agents on the fetus.
- Trial name
- NCT07386054
- Testing
- binaural beats, Midazolam
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Hypotension, Anesthesia, Local
The Relationship Between Abdominal Circumference: Hip Ratio and Ephedrine Requirement
This prospective observational study aimed to investigate whether there is a relationship between weight, height, BMI, abdominal circumference (AC), hip circumference (HC), and AC-to-hip ratio with the incidence of hypotension in…
- Conditions
- Hypotension, Anesthesia, Local, Cesarean Section Complications
- Trial name
- NCT05382624
- Testing
- Abdominal circumference was measured at the umbilical level in the standing position at the end of a normal expiration.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Dexamethasone, Magnesium Sulphate
Dexamethasone Versus Magnesium Sulphate as an Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Plane Block for Postoperative Analgesia in Elective Caesarean Section Under Spinal Anesthesia
This study aims to compare the efficacy of adding dexamethasone and magnesium sulfate as an adjuvant to bupivacaine in bilateral erector spinae block in postoperative pain control in patients undergoing caesarean section under…
- Conditions
- Dexamethasone, Magnesium Sulphate, Adjuvant, Ultrasound
- Trial name
- NCT07139522
- Testing
- Bupivacaine, Dexamethasone, Magnesium sulphate
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
Hypotension, Spinal Anesthesia
Prophylactic Ondansetron for Preventing Spinal Anesthesia-Induced Hypotension in Elective Cesarean Section
Spinal anesthesia is the preferred technique for elective cesarean section, but it frequently causes maternal hypotension due to sympathetic blockade and the Bezold-Jarisch reflex, which can threaten both mother and baby.
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Section
- Trial name
- NCT07886151
- Testing
- Ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital