Clinical trials: Anesthesia for Cesarean Delivery
Postoperative Pain Management, Obstetric Anesthesia
Effect of Bilateral Ultrasound-Guided TAP Block on Quality of Recovery in Cesarean Delivery Patients Receiving Intrathecal Morphine
This prospective, assessor-blinded observational cohort study will investigate the effect of adding bilateral ultrasound-guided transversus abdominis plane (TAP) block to standard intrathecal morphine (ITM) analgesia on the…
- Conditions
- Postoperative Pain Management, Obstetric Anesthesia, Recovery From Anesthesia
- Trial name
- QoR-TAP (NCT07145619)
- Testing
- Spinal Anesthesia with Intrathecal Morphine Only, Spinal Anesthesia with Intrathecal Morphine plus Bilateral TAP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- MEHMET GÖKHAN TAFLAN
Adverse Effect
The Potency of Prophylactic Norepinephrine and Phenylephrine Boluses for Postspinal Anesthesia Hypotension
The purpose of this study is to investigate the potency between prophylactic norepinephrine and phenylephrine boluses for postspinal anesthesia hypotension in patients with severe preeclampsia during caesarean section.
- Trial name
- NCT05035472
- Testing
- Phenylephrine, Norepinephrine
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Pregnancy, Cesarean Delivery
Sublingual Misoprostol & Isoflurane During Caesarean Section
Misoprostol would reduce the uterine bleeding after caesarean delivery, without harmful effects on either mother or baby. The investigators postulated that the use of sublingual misoprostol during isoflurane anaesthesia for…
- Trial name
- NCT01466530
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 366 people
- Sponsor
- Mansoura University
Unplanned Caesarean Section
Chloroprocaine 3% - Epidural Anesthesia in Unplanned Caesarean Section
The study evaluate the quality of epidural anaesthesia and the safety of Chloroprocaine HCl 3% compared with Ropivacaine HCl 0.75% in patients with an epidural catheter in situ undergoing unplanned Caesarean section.
- Trial name
- NCT02919072
- Testing
- Chloroprocaine, Ropivacaine
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- Sintetica SA
Cesarean Delivery, Cesarean Delivery; Neuraxial Opioids
Adding Dexmedetomidine or Clonidine to Spinal Anesthesia for Cesarean Delivery
This study will examine whether addition of dexmedetomidine or clonidine (two alpha-2 adrenergic agonists) will improve the comfort of patients during spinal anesthesia for cesarean delivery.
- Conditions
- Cesarean Delivery, Cesarean Delivery; Neuraxial Opioids, Spinal Anesthesia for Cesarean Section, Dexmedetomidine
- Trial name
- NCT07567495
- Testing
- Clonidine, Dexmedetomidine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Columbia University
Hypotension
The Effect of Ondansetron on Spinal Anesthesia in Caesarean Section
The purpose of this study is to compare the administration of two different doses of ondansetron to placebo to prevent hypotension and bradycardia following spinal anaesthesia.
- Trial name
- NCT03931863
- Testing
- Ondansetron 4mg, Ondansetron 8mg, 100ml normal saline 0.9 percent
- Where
- Greece
- Volunteers
- 180 people
- Sponsor
- Aretaieion University Hospital
Cesarean Section, Preoperative Anxiety
Effects of Sedation on Spinal Anesthesia-induced Maternal Hypotension
Background: This study was designed to investigate the effect of sedation on the occurrence of maternal hypotension in preoperatively anxious parturients undergoing urgent category-1 Cesarean section (C/S) under spinal…
- Conditions
- Cesarean Section, Preoperative Anxiety, Spinal Anesthesia, Sedation
- Trial name
- NCT02732197
- Testing
- Sedation, No sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Van Training and Research Hospital
Anesthesia; Adverse Effect, in Labor and Delivery
Incidence of Anesthesia-related Adverse Events and Obstetric Complications After Cesarean Delivery
Recruit the parturients who underwent cesarean delivery at Far Eastern MemorialHospital during 2012-2016. After reviewing medical record related to the pregnancy, demographic data, prenatal exam, laboratory data, indication for…
- Trial name
- NCT03391648
- Testing
- Observation
- Where
- Taiwan
- Volunteers
- 505 people
- Sponsor
- Far Eastern Memorial Hospital
Cesarean Section, Anesthesia, Spinal
Intrathecal Dexmedetomidine vs Epinephrine
Several studies have shown that adding dexmedetomidine or epinephrine to single-dose spinal analgesia preparations improves the length and/or speed of onset of the sensory block and post-operative pain management without…
- Trial name
- NCT06418308
- Testing
- Dexmedetomidine, Epinephrine, Standardized Spinal Mixture
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Complications; Cesarean Section, Anesthesia; Reaction
Carbetocin Trial: Carbetocin Appropriate Rate Better Equilibrium Between Tonus (TOnus) and CIrculatioN
Postpartum haemorrhage (PPH) is an obstetric emergency and defined as a blood loss of ≥500ml after vaginal birth and ≥1000ml after caesarean section (CS) and/or the need for blood transfusion within 24 hours after delivery (World…
- Trial name
- CARBETOCIN (NCT02221531)
- Testing
- Carbetocin Short-infusion, Carbetocin Bolus application
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- University Hospital, Basel, Switzerland
Anesthesia; Sexual, Analgesia
The Effect of Peripheral Nerve Blocks on Postoperative Analgesia in Elective Cesarean Section
The goal of this prospective randomized study was to compare the efficacy of transversus abdominis plane block and transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean section…
- Trial name
- NCT05758233
- Testing
- Patients undergoing transversalis fascia plane block, Patients undergoing transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Intraoperative Hypotension
The Use of Integrated Pulmonary Index During Cesarean Section Under Spinal Anesthesia
Postspinal hypotension (PSH) is a common side effect with an incidence of 15.3 to 33% that can result in organ hypoperfusion and ischemic events.
- Trial name
- NCT05237856
- Testing
- Capnometry Monitorization
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Anesthesia, Spinal, Cesarean Section
Combined Colloid Preload And Crystalloid Coload Versus Crystalloid Coload During Spinal Anesthesia for Cesarean Delivery
The study will compare one technique of fluid administration (combined colloid preload and crystalloid colaod) with another one (crystalloid coload) during elective cesarean delivery performed under spinal anesthesia.
- Trial name
- NCT02961842
- Testing
- 500 mL Colloid Preload, Spinal Anesthesia, Intrathecal Bupivacaine
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Mansoura University
Analgesia
Effect of Intrathecal Morphine on Urinary Bladder Function and Recovery in Patients Having a Cesarean Delivery
The enhanced recovery anesthesia concept has been widely adopted, including cesarean delivery. Modern obstetrical anesthesia aims to offer an experience to a patient undergoing a cesarean delivery similar to normal vaginal…
- Trial name
- NCT05042817
- Testing
- 100 mcg morphine, 0.9% NaCl, 50 mg prilocaine + 2.5 mcg sufentanil
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- University of Liege
Caesarean Section;Stillbirth
Neonatal Evaluation of Norepinephrine Infusion in Spinal Anesthesia for Cesarean Section
This retrospective study aims to evaluate the fate of children born by cesarean section under spinal anesthesia with or without norepinephrine as vasopressor support for anesthesia.
- Trial name
- NECS (NCT04245891)
- Where
- France
- Volunteers
- 265 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Breast Feeding, Analgesia
Breastfeeding Evaluation of Puerperal Women Who Had Cesarean Delivery in Our Hospital
İntroduction The World Health Organisation (WHO) and United Nations Children's Fund (UNICEF) recommends that infants are exclusively breastfed for a minimum of 6 months, with continued breastfeeding recommended until child age of…
- Trial name
- NCT06682871
- Testing
- Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Intraoperative Shivering, Ketamine With Shivering
Comparison of Ketamine Plus Dexamethasone Versus Ketamine Alone for Prevention of Severe Shivering After Spinal Anesthesia in Cesarean Section
Shivering is one of the most distressing events of the birth experience for patients. Shivering that occurs with spinal anesthesia is a frequent event, with a reported incidence of up to 50-65%.
- Conditions
- Intraoperative Shivering, Ketamine With Shivering, Dexamethasone for Shivering, Severe Shivering
- Trial name
- NCT06091657
- Testing
- Ketamine Hydrochloride
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Kasr El Aini Hospital
Phenylephrine
Anxiety and Phenylephrine Dosage
Spinal anesthesia is considered gold standard anesthetic technique of choice for cesarean delivery (1). However its use is frequently associated with maternal hypotension, which occurs in up to 71% of cases, without prophylactic…
- Trial name
- NCT03696732
- Testing
- Anxiety questionnaire, VAS questionnaire
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Obesity, Pregnancy Related
Combined Spinal Epidural Anesthesia in Obese Patients Undergoing Cesarean Surgery
This study investigated the maternal and fetal effects during performance of CSEA in the left lateral decubitus and sitting positions in obese pregnant women undergoing elective cesarean section.
- Conditions
- Obesity, Pregnancy Related, Cesarean Section Complications, Spinal Anaesthetic Poisoning of Undetermined Intent
- Trial name
- NCT04612998
- Testing
- left lateral decubitus position, sitting position, The use of intravenous ephedrine.
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Anesthesia, Spinal, Cesarean Section
Ultrasonography Versus Palpation for Spinal Anesthesia in Obese Parturients Undergoing Cesarean Delivery
The study will compare between preprocedural ultrasonography and the conventional palpation technique for spinal anesthesia in obese parturients undergoing elective cesarean delivery
- Conditions
- Anesthesia, Spinal, Cesarean Section, Spinal Ultrasound
- Trial name
- NCT03792191
- Testing
- Lumbar Spinal Ultrasonography, Conventional Landmark Palpation, Spinal Anesthesia
- Where
- Egypt
- Volunteers
- 280 people
- Sponsor
- Mansoura University