Clinical trials: Anesthetic, Inhalation
Catheterization
Intravenous Cannulation In Children During Sevoflurane Induction
This interventional simple-blind,randomized trial has included 90 children of American Society of Anesthesiologist (ASA) physical status I or II aged between 1 to 12 years of either sex, scheduled for for outpatient minor surgery…
- Trial name
- NCT03254303
- Testing
- Difficulty of catheterization in group 60 s, Difficulty of catheterization in group 90 s, Difficulty of catheterization in group 120 s
- Volunteers
- 90 people
- Sponsor
- Leila mansali stambouli
Balanced Anesthesia
Surgical Pleth Index (SPI) Guided Analgesia During Sevoflurane Anesthesia
The aim of the present study was to compare SPI guided analgesia with standard clinical practise during general anesthesia using a balanced setting of sevoflurane and sufentanil anesthesia.
- Trial name
- NCT01525537
- Testing
- administration of sufentanil, sufentanil
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- University Hospital Schleswig-Holstein
Pulmonary Aspiration of Gastric Contents, Adverse Effects in the Therapeutic Use of Other and Unspecified General Anaesthetics
Safety of Gastric Volume Emptying After the Intake of Maltodextrin and Glutamine
Carbohydrates (CHO)-based drinks 2h before the induction of anesthesia are recommended to decrease insulin resistance. The addition of glutamine (GLN) in these beverages may enhance the benefits of CHO alone.
- Conditions
- Pulmonary Aspiration of Gastric Contents, Adverse Effects in the Therapeutic Use of Other and Unspecified General Anaesthetics, Pulmonary Aspiration During Anaesthetic Induction
- Trial name
- NCT01798342
- Testing
- Maltodextrin, Glutamine
- Where
- Brazil
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Federal University of Mato Grosso
Aromatherapy
The Efficacy of Sweet Orange Oil Inhalation in Management of Dental Anxiety and Pain
Aim of the study To evaluate the effectiveness of sweet orange oil inhalation in reducing dental anxiety and pain in children undergoing local anaesthetic administration.
- Trial name
- NCT06063512
- Testing
- sweet orange oil inhalation
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oxygen Consumption, Sevoflurane
Oxygen Consumption and Sevoflurane Uptake Based on Physiological Dead Space Estimation
In this study, the investigators will evaluate whether the delivered fraction of oxygen (O2) and sevoflurane administered through a a closed circuit and calculated on the basis of the estimations of O2 consumption (VO2) and…
- Conditions
- Oxygen Consumption, Sevoflurane, Anesthetics, Inhalation, Surgery
- Trial name
- NCT05511584
- Testing
- VO2 estimation, SEVOup estimation
- Where
- Spain
- Volunteers
- 17 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Drug Interactions, Anesthesia, Conduction
Interaction of Sevoflurane Propofol and Remifentanil in Anesthesia for Laparoscopic Surgery
Recently a new model for the interaction of sevoflurane propofol and remifentanil was developed. The potency of any combination of the three drugs is defined as probability that a subject tolerates laryngoscopy without movement…
- Trial name
- SPRV (NCT02457442)
- Testing
- Propofol and Remifentanil, Sevoflurane and Remifentanil, SPR 1
- Where
- Switzerland
- Volunteers
- 172 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Adverse Effect of Other General Anesthetics, Anesthesia Intubation Complication
Comparison of Tapered- vs. Cylindrical-shaped Tube Cuffs Pressure Alteration With Nitrous Oxide
When using nitrous oxide for general anesthesia, nitrous oxide diffusion induces intracuff hyperinflation of the endotracheal tube.
- Conditions
- Adverse Effect of Other General Anesthetics, Anesthesia Intubation Complication, Inhalation of Nitrous Oxide, Trachea
- Trial name
- NCT01812915
- Testing
- Cylindrical-shape cuff ETT (Group C), Tapered-shape cuff ETT (Group T)
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- DongGuk University
Airway Complication of Anaesthesia, Healthy
The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects
The investigators hypothesize that propofol, when compared to sevoflurane, causes the upper airway to collapse more easily and causes less activity in the tongue muscle.
- Trial name
- NCT01557920
- Testing
- Propofol, Sevoflurane
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Anesthesia
the Impact of Noise on Requirements of Anesthetics During General Anesthesia
The investigators hypothesize that the noise level in the operating theatre influences the patients' requirements of anesthetics.
- Trial name
- NCT02534285
- Testing
- hearing protection
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technische Universität Dresden
Nitrous Oxide, Electroencephalography
Effect of Nitrous Oxide on EEG
Our recent preclinical observations suggest that monitoring of slow electroencephalogram (EEG) oscillations may be used to predict the efficacy of rapid-acting antidepressants such as ketamine or nitrous oxide.
- Conditions
- Nitrous Oxide, Electroencephalography, Anesthetic, Inhalation
- Trial name
- HUMANOID (NCT04884893)
- Testing
- Nitrous Oxide
- Where
- Finland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Cytokines, Inflammatory
Cytokines and Sevoflurane During Surgery
The aim of the present study was to evaluate the effects of anaesthesia with sevoflurane and surgery on cytokines response.
- Conditions
- Cytokines, Inflammatory, Sevoflurane
- Trial name
- NCT01231477
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Renal Cell Carcinoma
Anesthesia and Cancer Study: Renal Cell Carcinoma
This study investigates the influence of type of anesthesia on recurrence and survival of renal cell carcinoma in patients undergoing nephrectomy.
- Trial name
- NCT04503148
- Testing
- Propofol, Inhaled General Anesthetics
- Where
- South Korea
- Volunteers
- 562 people
- Sponsor
- Seoul National University Hospital
General Anesthesia, Inhalation; Gas
End Tidal Anesthetic Concentration in Different Anesthesia Techniques Where Depth of Anesthesia Adjusted With Entropy
The aim of this study is to adjust the end tidal inhalation anesthetic concentration by observing the entropy value in patients who will be provided anesthesia maintenance with volatile anesthetics after applying the routine…
- Trial name
- NCT04203290
- Testing
- Bupivacaine, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul University
Analgesia
Evaluation of Surgical Stress Index (SSI) During Sevoflurane/Remifentanil Anesthesia
The aim of the present prospective randomized study was to challenge the ability of SSI to detect painful stimulation during sevoflurane - remifentanil anesthesia.
- Trial name
- NCT00791791
- Testing
- standardized pain stimulus
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University Hospital Schleswig-Holstein
Pain
Evaluation of Pain Intensity During Bone Marrow Biopsy Performed With Inhalation of Pre-Mixed 50 Per Cent Nitrous Oxide and Oxygen Mixture.
Bone marrow biopsy is a painful medical procedure often performed with local anesthetic. Therefore a double-blind, randomized, controlled trial was carried out in 330 adult patients who where referred for bone marrow biopsy and…
- Trial name
- NCT00219713
- Testing
- nitrous oxide and oxygen
- Where
- France
- Volunteers
- 280 people
- Sponsor
- Poitiers University Hospital
Anaesthetic Induction, Respiratory Complications of Care
Two Modalities of Ventilation on the Occurrence of Respiratory Complications During Inhalational Anaesthetic Induction in Children
Induction of anesthesia by inhalation is the most common method of induction (70% in France) for young children admitted for non-emergency surgery. It has the advantage of not requiring an intravenous line.
- Conditions
- Anaesthetic Induction, Respiratory Complications of Care, Pediatrics, Ventilation
- Trial name
- PEDIAMOVE (NCT07767851)
- Testing
- Induction with PEEP (5 cmH2O) and PSV (2-12 cmH2O), Induction in spontaneous breathing
- Where
- 9 sites in France
- Volunteers
- 2,032 people
- Sponsor
- Hospices Civils de Lyon
Acute Pain
Comparison of Postoperative Outcomes Between Surgeries Anaesthetized With Propofol and Inhalational Anaesthetics
Propofol used as anaesthesia in surgery had shown small postoperative analgesic benefits over inhalational anaesthetics in some meta-analyses. It was also associated with reduced risk of postoperative nausea and vomiting.
- Trial name
- NCT03875872
- Testing
- Propofol, inhalation anaesthetics
- Where
- Hong Kong
- Volunteers
- 3,922 people
- Sponsor
- The University of Hong Kong
Colorectal Neoplasms
Anesthetic Technique on Immune Response in Colorectal Cancer
Knowing the fact that the anesthetic substances can alter the immune response during the surgery, the purpose of the study is to evaluate the influence of two general anesthetic techniques - inhalation vs.
- Trial name
- T-IL-Co-ReCa (NCT01902849)
- Testing
- blood sampling for IL measurement
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Pain
ANI and NoL Index Variations After Standard Nociceptive Stimulus at 0, 50, 25 % of Inhaled N2O in the Anesthetic Mixture
N2O has been used during general anesthesia (GA) for more than 100 years. It is known to have anesthetic agents sparing effect. But small is know on his real analgesic effect during GA.
- Trial name
- NCT02701478
- Testing
- N2O exposure
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Pain, Acute, Trauma Injury
Use of Penthrox in Extra-hospital Traumatology
In pre-hospital settings, the administration of analgesics is often delayed because of difficult patient access (incarceration), difficulty finding a venous pathway or patient refusal.
- Conditions
- Pain, Acute, Trauma Injury, Pain Management
- Trial name
- UPETEH (NCT03537001)
- Testing
- Penthrox
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Tours