Clinical trials: Anesthetic Depth
Anesthesia, Surgery
Sedline EEG Guided Depth of Anesthesia
The purpose of our study is to determine if monitoring sedation (how asleep patients are under general anesthesia) using a device called a Sedline Monitor affects the amount of anesthesia patients receive.
- Trial name
- NCT05051982
- Testing
- Sedline EEG in View
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Indiana University
Mental Function
Restoration of Consciousness With Ultrasonic Deep Brain Stimulation During Anesthetic Sedation
The purpose of this study is to see if mental functions take place during different levels of anesthesia using two commonly used drug (propofol and dexmedetomidine) and will include low-intensity focused ultrasound pulsation…
- Trial name
- NCT07221539
- Testing
- Propofol for fMRI, Dexmedetomidine for fMRI, Dorsolateral prefrontal cortex (DLPFC) pulsation
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Dental Pain
Buffered Local Anesthetic
The purpose of this research study is to compare responses in children during dental injections of local anesthetic (used for numbing), while children are under deep sedation (breathing on their own, often with a loss of…
- Trial name
- NCT05757648
- Testing
- Non-buffered Anesthetic, Buffered Anesthetic, Onset
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Driving Impaired
Driving Performance After Deep Sedation for Outpatient Endoscopy
Many drugs used during anesthesia can reduce alertness and therefore present potential risks when driving a vehicle (risk of accident).
- Trial name
- NCT04948385
- Testing
- Propofol, No sedation
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Liege
Endotracheal Intubation, Deep Sedation
Inhaled Sedation Using the Anesthetic-conserving Device ( ANACONDA) in Prehospital Emergency Medecine.
Achieving the optimal sedation level for patient management is not always possible using our standard intravenous medications in Pre-hospital Emergency medicine.
- Trial name
- ANACONDA (NCT04141267)
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Mental Function
Ultrasonic Deep Brain Stimulation During Anesthetic Sedation
The purpose of this study is to see if mental functions take place during different levels of anesthesia. The researchers expect to gain a deeper understanding of mental function during different levels of anesthesia, and to…
- Trial name
- NCT05495945
- Testing
- Low-intensity focused ultrasound pulsation (LIFUP), Functional Magnetic Resonance Imaging (fMRI) using Propofol
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Anesthesia
Comparative Population Pharmacodynamic Modeling for Sevoflurane Effects Using ADMS and Bispectral Index
The investigators want to compare the performance of anesthetic depth monitoring for sedation (ADMS) to the bispectral index (BIS) as electroencephalographic measures of sevoflurane effect using two combined sigmoidal Emax models…
- Trial name
- NCT03069456
- Testing
- BIS, ADMS
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chonnam National University Hospital
Emergence Delirium (Derlenme Deliryumu)
Brain Monitors to Reduce Child Confusion After Anesthesia
The goal of this clinical trial was to learn if using a brain monitor to adjust anesthesia (sleep medicine) during surgery could prevent emergence delirium (severe confusion and agitation upon waking) in children aged 2 to 12…
- Trial name
- NCT07826559
- Testing
- BIS-Guided Anesthesia, Standard Care Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Baskent University
Delirium, Cognitive Disorders
Anesthetic Depth and Postoperative Delirium Trial - 2
Recent limited evidence suggests that anesthetic depth may influence postoperative cognitive outcomes, however, the mechanism between this association is unclear.
- Trial name
- ADAPT2 (NCT01983384)
- Testing
- Processed EEG-guided anesthetic depth
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Electroencephalography Spectral Edge Frequency, Anesthetic Depth
EEG to Monitor Propofol Anesthetic Depth in Infants and Toddlers
The goal of this study is monitor anesthetic depth of children undergoing propofol anesthesia using electroencephalography (EEG). The main questions it aims to answer are: 1.
- Trial name
- NCT05701748
- Testing
- Stimuli
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia