Clinical trials: Anesthetics, Local, open to volunteers
Comparison of Buffered Versus Non Buffered Local Anesthetic In Inflamed Tissues
"Comparison of Buffered Versus Non-Buffered Local Anesthetic in Patients With Inflamed Tissues for Pain Perception, Onset, Duration and Adverse Effects"
This study aims to determine whether buffered or non-buffered local anesthetic (LA) is more effective and safer for managing pain in patients with inflamed tissues undergoing surgical procedures.
- Trial name
- NCT07592143
- Testing
- Buffered Local Anesthesia
- Volunteers
- 68 people
- Sponsor
- King Edward Medical University
Laparoscopic Cholecystectomy Surgery, Analgeisa
Pain Relief Following Laparoscopic Cholecystectomy While Comparing Intra Abdominal Versus Sub Cutaneous Local Anesthetic Administration
Laparoscopic cholecystectomy involves removal of gallbladder through small incision ports resulting in faster recovery. Small incisions are less painful and hence local anesthesis administered can be effective for pain…
- Conditions
- Laparoscopic Cholecystectomy Surgery, Analgeisa, Local Anesthetic Infiltration
- Trial name
- NCT07409688
- Testing
- Intraoperitoneal local anesthetic administration, Sub cutaneous administration of local anesthetic
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Laparoscopic Cholecystectomy, TAP Block
Laparoscopic-Assisted Transversus Abdominus Plane Block Versus Intraperitoneal Irrigation of Local Anesthetic for Patients Undergoing Laparoscopic Cholecystectomy
This study is being performed to investigate whether the administration of local anaesthetic into the muscles in the abdomen or onto squirting the local anaesthetic onto the liver following keyhole gallbladder surgery is more…
- Conditions
- Laparoscopic Cholecystectomy, TAP Block, Local Anesthetic
- Trial name
- NCT06714279
- Testing
- Tap Block - Bupivacaine, Intraperitoneal infiltration to liver
- Where
- Ireland
- Volunteers
- 144 people
- Sponsor
- Royal College of Surgeons, Ireland
Regional Anesthesia Morbidity, Cesarean Section Complications
Height Adjusted Versus Standardized Dose of Bupivacaine for Spinal Anesthesia
General anesthesia during pregnancy is associated with several major risks including unanticipated difficult airway, pulmonary aspiration, and specific anesthetic effects on the newborn.
- Conditions
- Regional Anesthesia Morbidity, Cesarean Section Complications, Local Anesthetic Complication
- Trial name
- RAMCES (NCT05233462)
- Testing
- standardized dose, adjusted dose
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Caen
Cesarean Section, Local Anesthetic
Chloroprocaine 1% Versus Ropivacaine 0,75% During Cesarean Section
This will be a prospective randomized study, aiming at comparing an intrathecal fixed dose of chloroprocaine 1% versus an intrathecal fixed dose of ropivacaine 0.75% in elective cesarean sections
- Trial name
- annie-mariana (NCT06376058)
- Testing
- Chloroprocaine 1% Injectable Solution, Ropivacaine 0.75% Injectable Solution
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
General Anesthesia, Spinal Anesthesia
General Anesthesia Versus Spinal Anesthesia With Local Anesthetic Infiltration for Buccal Mucosal Graft in Urethroplasty
This study aims to compare general anesthesia and spinal anesthesia with local anesthetic infiltration for buccal mucosal graft (BMG) in urethroplasty.
- Conditions
- General Anesthesia, Spinal Anesthesia, Local Anesthetic Infiltration, Buccal Mucosal Graft
- Trial name
- NCT07074730
- Testing
- Spinal anesthesia, General anesthesia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Pain Related to Local Anesthetic Administration for Nexplanon Placement
Pain Related to Local Anesthetic Administration for Nexplanon Placement
This research study is being conducted to see if using buffered lidocaine for Nexplanon placement decreases pain associated with administering local anesthesia compared to unbuffered lidocaine, which is currently used in clinic.
- Trial name
- NCT07008222
- Testing
- we will prepare 3cc of buffered lidocaine consisting of 2.7cc of 1% lidocaine and 0.3cc of 8.4% sodium bicarbonate, Unbuffered lidocaine
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Spinal Anesthesia, Local Anesthetic
Age-Based and Weight-Based Bupivacaine Dosing for Pediatric Spinal Anesthesia for Elective Infra-Umbilical Surgeries
Pediatric anesthesia presents distinctive challenges, particularly concerning appropriate dosage administration of local anesthetics for spinal anesthesia (SA).
- Conditions
- Spinal Anesthesia, Local Anesthetic, Bupivacaine
- Trial name
- NCT06801600
- Testing
- Weight-based dosing, Age-based dosing
- Volunteers
- 60 people
- Sponsor
- Cairo University
Regional Anesthesia, Local Anesthetic
Mixed Local for Sciatic Block
Choice of local anesthetics is the major determinant of the characteristics of a peripheral nerve block. Short acting local anesthetics while provides faster onset suffer from shorter duration.
- Trial name
- NCT06671028
- Testing
- Ropivacaine and Lidocaine, Ropivacaine 0,5%
- Volunteers
- 110 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's