Clinical trials: Aneuploidy Rate
Infertility
Influence of a Prematuration Culture With a Phosphodiesterase-3 Inhibitor (PDE3-I) on Embryonic Aneuploidy Rate and Developmental Potential
A single centre randomised controlled trial investigating the influence of a novel prematuration system (PMS) using a phosphodiesterase-3 inhibitor for in-vitro maturation of oocytes - pilot study.
- Trial name
- NCT00822874
- Testing
- prematuration culture
- Where
- Belgium
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Incubator Stay, Total Blastulation
Impact of Dry vs Humidified Culture Conditions on Blastocyst Development and Aneuploidy: A Time-lapse Sibling Oocyte Study
IVF incubators are essential for maintaining the micro-environment required for embryo development. Incubator technology has progressed from early humidified box systems to benchtop and now time-lapse platforms, driving the…
- Conditions
- Incubator Stay, Total Blastulation, Blastocyst Quality, Biopsy Rate
- Trial name
- NCT07270250
- Testing
- K- system incubator
- Where
- United Arab Emirates
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Trisomy 21
Down Syndrome Screening Based on Dried Blood Spots and Cell-free Fetal DNA
There are 26,600 Down Syndrome newborns every year in China. The economic burden of this disease is 65,000 USD for lifetime of every patient.
- Trial name
- DBS&CFF (NCT01837979)
- Testing
- cell-free fetal DNA
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Infertility
A Benchtop Incubator Prospective Study
The use of extended embryo culture to the blastocyst stage and preimplantation genetic testing for aneuploidy (PGT-A) has enabled identification and selection of embryos with the best developmental potential and improved in vitro…
- Trial name
- NCT04969575
- Testing
- Insemination and culture, Media refreshment Group 1, Culture media preparation and refreshment
- Where
- United Arab Emirates
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility
Influence of a Prematuration Culture With a Phosphodiesterase-3 Inhibitor (PDE3-I) on Embryonic Aneuploidy Rate and Developmental Potential
A single centre randomised controlled trial investigating the influence of a novel prematuration system (PMS) using a phosphodiesterase-3 inhibitor for in-vitro maturation of oocytes
- Trial name
- NCT00823420
- Testing
- prematuration culture
- Where
- Belgium
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Aneuploidy, Infertility
Nuclear Magnetic Resonance for Embryo Ploidy Selection
This study aims to validate the embryo culture medium analysis by nuclear magnetic resonance spectroscopy, as a faster and less-costly alternative to preimplantation genetic test for aneuploidy which could significantly enhance…
- Trial name
- NCT05488236
- Testing
- Nuclear magnetic resonance analysis of embryo culture medium
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Aneuploidy Rate
Aneuploidy Rate and Stimulation Protocol: Recombinant Follicle Stimulating Hormone (FSH) Versus Human FSH
Several stimulation protocols have been used in in vitro fertilization (IVF) in a cycle of egg donation; recombinant FSH and human FSH are included. The effect of each kind of hormone on aneuploidy rate it is unknown.
- Trial name
- NCT01164943
- Testing
- Stimulation with human FSH, Stimulation with recombinant FSH
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IVI Madrid