Clinical trials: Aneurysm, Dissecting
Aortic Dissection, Intramural Hematoma
DARTS I Feasibility Study
The objective of this study is to investigate the feasibility and clinical benefits of the AMDS to treat patients with acute DeBakey type I dissections and/or intramural hematomas (IMH) involving the ascending aorta and aortic…
- Trial name
- DARTS I (NCT03035643)
- Testing
- AMDS
- Where
- 5 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Ascyrus Medical LLC.
Thoracic Aortic Dissection
DISSECT-N Post Market Data Collection Registry
DISSECT-N is a post-market registry designed to assess real-world safety and effectiveness of Valiant Navion Thoracic Stent Graft System in the treatment of thoracic aortic dissections in real world practice.
- Trial name
- DISSECT-N (NCT04267055)
- Testing
- Valiant Navion Thoracic Stent Graft System
- Where
- 22 sites in United States, Denmark and 8 more
- Volunteers
- 102 people
- Sponsor
- Medtronic Cardiovascular
Cardiac Rehabilitation Program Following the Management of ACS in Patients Presenting With SCAD
Modalities And Safety Of Cardiac Rehabilitation In A Population Managed For Spontaneous Hematoma Or Coronary Disruption
Spontaneous Coronary Artery Dissection (SCAD) is a rare and often misdiagnosed cause of Acute Coronary Syndrome (ACS) affecting predominantly young women without cardiovascular risk factors.
- Trial name
- READAPT-DISCO (NCT05744947)
- Testing
- Data collection
- Where
- 29 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Bordeaux
PAD - Peripheral Arterial Disease, PAD
Tack Optimized Balloon Angioplasty Post-Market Study
The objective of this study is to obtain outcomes following dissection repair with the Tack Endovascular System in a broad population of patients undergoing endovascular treatment of lesions within the superficial femoral…
- Conditions
- PAD - Peripheral Arterial Disease, PAD, Dissection, Arterial Dissection
- Trial name
- TOBA PMS (NCT05361967)
- Testing
- The Tack Endovascular System
- Where
- 10 sites in United States
- Volunteers
- 6 people
- Sponsor
- Spectranetics Corporation
Spontaneous Coronary Artery Dissection
A Study of SCAD Using Stress Contrast Echocardiography
This study aims to fill knowledge gaps regarding microvascular perfusion and pressor response to stress among patients with history of spontaneous coronary artery dissection (SCAD) using stress contrast echocardiography.
- Trial name
- NCT07178509
- Testing
- Stress Echocardiography with Contrast
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Spontaneous Coronary Artery Dissection
Spontaneous Coronary Artery Dissection Registry (DIssezioni Spontanee COronariche ITalian-SPAnish)
The study will investigate the clinical features, acute management and follow up of patients affected by spontaneous coronary artery dissection
- Trial name
- DISCO-IT/SPA (NCT04415762)
- Volunteers
- 314 people
- Sponsor
- San Luigi Gonzaga Hospital
Spontaneous Coronary Artery Dissection
International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry
The aim of "iSCAD," the International Spontaneous Coronary Artery Dissection (SCAD) Registry, is to serve as an internationally collaborative, multicenter registry coordinated by an experienced and centralized coordinating center…
- Trial name
- NCT04496687
- Where
- 31 sites in United States, Australia
- Volunteers
- 2,000 people
- Sponsor
- SCAD Alliance
Vascular Diseases
Superior Mesenteric Artery Dissection
This study investigate CT images of patients with spontaneous isolated superior mesenteric artery dissection (SISMAD). The investigators also further analyze the CT morphological differences between different options, aiming to…
- Trial name
- NCT03669380
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Tongji Hospital
Stroke (CVA) or TIA, Headache, Migraine
Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache
Post stroke headache occurs in approximately 10-23% of all stroke patients. Its onset is shortly after experiencing a stroke, or stroke like event, and persists for at least three months.
- Conditions
- Stroke (CVA) or TIA, Headache, Migraine, Botulinum Toxins, Type A, Cerebral Venous Sinus Thrombosis
- Trial name
- NCT04580238
- Testing
- Botox 200 UNT Injection, Non Botox based Standard of Care Treatments for Headache/Migraine
- Where
- Canada
- Sponsor
- University of Alberta
Cervical Artery Dissection, Stroke
Looking For Genetic and Environmental Risk Factors and Therapeutic Aspects in Cervical Artery Dissections
The main purpose of this study is to look for genetic and environmental risk factors of cervical artery dissections, a major cause of ischemic stroke in young adults, in a large multicenter case-control trial
- Conditions
- Cervical Artery Dissection, Stroke, Brain Infarction
- Trial name
- CADISP (NCT00657969)
- Where
- 24 sites in Argentina, Belgium and 7 more
- Volunteers
- 4,169 people
- Sponsor
- Cervical Artery Dissections and Ischemic Stroke Patients - Consortium
Cerebrovascular Disorders, Vascular: Intracranial
International Intracranial Dissection Study
Cervicocerebral artery dissection is a major cause for stroke in young adults. While knowledge of cervical artery dissection (CeAD) has increased thanks to a number of high quality studies, knowledge on intracranial artery…
- Conditions
- Cerebrovascular Disorders, Vascular: Intracranial, Intimal Dissection, Stroke
- Trial name
- I-IDIS (NCT02756091)
- Testing
- No study-specific intervention
- Where
- 3 sites in Japan, Switzerland
- Volunteers
- 500 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Fibromuscular Dysplasia, Spontaneous Coronary Artery Dissection
Defining the Basis of Fibromuscular Dysplasia (FMD)
The purpose of this study has evolved and expanded since its inception. Originally the intent was to establish the functional, molecular and genetic profile of fibroblasts from Fibromuscular Dysplasia (FMD) patients as compared…
- Conditions
- Fibromuscular Dysplasia, Spontaneous Coronary Artery Dissection, Cervical Artery Dissection
- Trial name
- DEFINE (NCT01967511)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Dissecting Aneurysm of the Thoracic Aorta
Effects of a Surgery-induced Peripheral Inflammatory Response on the Blood Brain Barrier
The purpose for this study is to determine if surgery (repair of descending thoracic aneurysm) causes a temporary decrease in the Blood Brain Barrier's ability to remove drugs from the brain back into the blood.
- Trial name
- NCT00878371
- Testing
- morphine
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Nova Scotia Health Authority
Cerebral Arteries, Dissection
Prospective Observation for Serial Changes in Acute Intracranial Artery Dissection Using HR-MRI
Intracranial artery disease has been more detected with development of HR-MR. HR-MR can depict vascular wall directly and give us more information beyond the pre-existing imaging modalities such as digital subtraction…
- Trial name
- NCT03213470
- Testing
- magnetic resonance imaging
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Asan Medical Center
Aortic Aneurysm, Aortic Dissection
Clinical Investigation of Clinical Safety and Performance of the SP-GRIPFLOW, Selective Cerebral Perfusion Catheter When Used for Cerebral Perfusion During Aortic Arch Repair
The purpose of this study is to determine if the SP-GRIPFLOW catheter (the catheter designed by Fuji Systems) is safe and how well it functions.
- Conditions
- Aortic Aneurysm, Aortic Dissection, Aortic Arch Aneurysm, Aortic Arch; Aneurysm, Dissecting
- Trial name
- NCT05421130
- Testing
- Selective Cerebral Perfusion Catheter
- Where
- 5 sites in Germany, Netherlands
- Volunteers
- 149 people
- Sponsor
- Fuji Systems Corporation
Coronary Artery Dissection, Spontaneous
Statin and Angiotensin-converting Enzyme Inhibitor on Symptoms in Patients With SCAD
An emerging cause of heart attack in young women is a dissection (or tear) in the coronary arteries. Many of these young women continue to have chest pain long after the tear has healed and this is thought to be due to problems…
- Trial name
- SAFER-SCAD (NCT02008786)
- Testing
- ramipril, rosuvastatin
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Cardiology Research UBC
Thoracoabdominal Aortic Aneurysm, Thoracoabdominal; Aortic, Aneurysm, Dissecting
Frailty and Physician Modified Fenestrated Endograft for Thoracoabdominal Aortic Pathologies
The primary objective of this single arm, prospective feasibility study, Impact of Frailty on Clinical Outcomes of Patients Treated for Thoracoabdominal and Complex Abdominal Aortic Aneurysms with Physician-Modified Fenestrated…
- Conditions
- Thoracoabdominal Aortic Aneurysm, Thoracoabdominal; Aortic, Aneurysm, Dissecting, Pararenal Aneurysm, Frailty Syndrome
- Trial name
- NCT04524247
- Testing
- Physician Modified Endografts
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Southern California
Connective Tissue Disease, Dissecting Aneurysm
Study of Heritable Connective Tissue Disorders
The purposes of this study are to identify the genes responsible for inherited connective tissue disorders and learn about the range of medical problems they cause.
- Conditions
- Connective Tissue Disease, Dissecting Aneurysm, Ehlers Danlos Syndrome, Marfan Syndrome
- Trial name
- NCT00001641
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Laparoscopic Cholecystectomy Surgery
Cystic Artery Dissection With Dorsal Infundibular Approach Versus Critical View of Safety
We evaluated the efficacy of combining cystic artery dissection with a dorsal infundibular approach in comparison to the critical view of safety.
- Trial name
- NCT07507292
- Testing
- critical view of saftey, cystic artery dissection with dorsal infundibular dissection
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Zagazig University
Spontaneous Coronary Artery Dissection
SCAD : a Registry of Spontaneous Coronary Artery Dissection
Spontaneous coronary artery dissection (SCAD) is an increasingly recognised cause of non-atherosclerotic acute coronary syndromes (ACS), predominantly afflicting young women without conventional atherosclerotic risk factors.
- Trial name
- SCAD (NCT06601270)
- Testing
- There are no interventions as the study is purely observational.
- Where
- 73 sites in Argentina, Austria and 22 more
- Volunteers
- 1,500 people
- Sponsor
- European Society of Cardiology