Clinical trials: Aneurysm, Intracranial
Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia
Epigenome-wide DNA Methylation Profiling in Aneurysmal Subarachnoid Hemorrhage and Delayed Ischemic Neurologic Deficit
The goal of this observational study is to investigate DNA methylation changes in adults with bleeding from brain aneurysm, which is called aneurysmal subarachnoid hemorrhage (aSAH), and their association with delayed ischemic…
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia, Cerebral Vasospasm After Subarachnoid Hemorrhage, Intracranial Aneurysm
- Trial name
- NCT06881329
- Where
- Poland
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Vascular Aneurysm
miRNA in Patients With Thoracic, Abdominal and Intracranial Aneurysms
To assess the expression of miRNA in patients with TAA, AAA in aneurysmatic tissue and to compare this expression with the healthy tissue in the same patient.
- Trial name
- miRNA (NCT05382611)
- Testing
- ngs next generation sequencing
- Where
- Czechia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Na Homolce Hospital
Intracranial Aneurysm, Subarachnoid Hemorrhage, Aneurysmal
Epidemiological Insights Into the Formation, Progression, and Rupture of Intracranial Aneurysms: A Retrospective, Multi-Center Hospital-Based Study in China
This is a retrospective, hospital-based and multi-center study aiming at investigating the potential exposures associated with the formation, progression, and rupture of intracranial aneurysms in Chinese population.
- Conditions
- Intracranial Aneurysm, Subarachnoid Hemorrhage, Aneurysmal, Cerebral Aneurysm, Brain Aneurysm
- Trial name
- NCT06456814
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Cerebral Aneurysm
Clopidogrel Hyper-Responsiveness: Incidence and Associated Outcomes in Patients With Cerebral Aneurysms
This registry study will investigate the incidence of and outcomes associated with clopidogrel hyper-responsive patients treated at Methodist Dallas Medical Center, beginning in January 2018, who suffered cerebral aneurysms.
- Trial name
- NCT05945563
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Methodist Health System
Aneurysm Cerebral
Complex Aneurysm Registry - Real-World Evidence Data Collection Intracranial Aneurysm Treatment Devices
To collect real-world evidence allowing assessment of functional, imaging, and safety outcomes of commercially available MicroVention devices used for the endovascular treatment of intracranial aneurysms (IA) at the direction of…
- Trial name
- CAR (NCT06215105)
- Testing
- Intracranial Aneurysm Devices
- Where
- 5 sites in United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Microvention-Terumo, Inc.
Brain Aneurysm
Current Treatment Modalities for Wide Necked Intracranial Aneurysms
Give an effective treatment for intracranial wide necked aneurysm and can detect the best method could be used. Improve the outcome of these patients and decease rate of recurrence and complications.
- Trial name
- NCT03852680
- Testing
- aneurysm clipping
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intracranial Aneurysm, Stent Complication
Stent-Assisted Coiling Followed by Ticagrelor Monotherapy Instead of Dual Antiplatelet Therapy in Unruptured Intracranial Aneurysm
The primary goal of the trial is to investigate whether the experimental arms (receiving the P2Y12 inhibitor Ticagrelor) compared with the control arm (taking dual antiplatelet therapy) could reduce bleeding complications in…
- Trial name
- SAC-TIDE (NCT06015477)
- Testing
- Ticagrelor monotherapy, Dual Antiplatelet Therapy
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Stable Angina, Unstable Angina
Serum Uric Acid Levels and Onset of Cardiovascular Diseases: a CALIBER Study
Serum uric acid level is a commonly measured biomarker. The association between serum uric acid level and the risk of developing cardiovascular diseases has been observed in some studies, while others showed controversial…
- Conditions
- Stable Angina, Unstable Angina, Myocardial Infarction, Unheralded Coronary Heart Disease Death
- Trial name
- NCT03425305
- Volunteers
- 180,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Aneurysm, Cerebral, Endovascular Procedures
Comparison of Two Different Antiplatelet Preparations for an Unruptured Intracranial Aneurysm
Perform a randomized comparison study of dual-antiplatelet (aspirin, prasugrel) and triple-antiplatelet (aspirin, clopidogrel, and cilostazol) preparation using P2Y12 assay in patients with high on-treatment platelet reactivity…
- Trial name
- NCT03581409
- Testing
- Aspirin, Prasugrel, Clopidogrel
- Where
- South Korea
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cotinine Levels, Arterial Aneurysm Wall Enhancement on HRMRI
A Study on the Correlation Between Cotinine Levels and Aneurysm Wall Enhancement on HRMRI.
This study aims to collect clinical, laboratory, and imaging data from patients with unruptured intracranial aneurysms, and collect blood or urine samples for cotinine testing.
- Trial name
- NCT06447714
- Testing
- smoke
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Abdominal Aortic Aneurysm, Coronary Heart Disease NOS
Heart Rate and Initial Presentation of Cardiovascular Diseases (Caliber)
Study of heterogeneity in associations between heart rate and the initial presentation of 12 cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease NOS, Unheralded Coronary Death, Intracerebral Haemorrhage
- Trial name
- NCT01947361
- Where
- United Kingdom
- Volunteers
- 1,961,286 people, healthy volunteers welcome
- Sponsor
- University College, London
Intracranial Aneurysm
Contrast-enhanced Magnetic Resonance Angiography Investigation of Intracranial Aneurysms and Prospective Study of Risk Factors
This is a prospective observational registry with intent to detect the prevalence of intracranial aneurysms with contrast-enhanced MR angiography (CE-MRA) at 1.5T, and to determine the risk factors such as high blood pressure and…
- Trial name
- EIIA (NCT00997698)
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Second Military Medical University
Intracranial Aneurysms
Ultra Coils From Start to Finish for the Endovascular Repair of Small Intracranial Aneurysms
The purpose of this study is to assess the safety and efficacy rates of the treatment of small intracranial aneurysms with Stryker Neurovascular's Target® 360 Ultra coils which are a type of platinum coils used to occlude…
- Trial name
- ULTRA (NCT02657772)
- Where
- 6 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.