Clinical trials: Aneurysm Thoracic
Pathology of the Thoracic Aorta, Aneurysm Thoracic
French Assessment of the Relay Plus and Relay NBS Plus Thoracic Stent-Graft
Stent treatment of thoracic aortic pathologies, including aneurysms, pseudo-aneurysms, dissections, intramural hematomas, penetrating ulcers and ruptures of the isthmus, seems to provide a likely benefit compared to surgery in…
- Conditions
- Pathology of the Thoracic Aorta, Aneurysm Thoracic, Pseudo-aneurysm, Thoracic, Dissection of Thoracic Aorta
- Trial name
- NCT05030740
- Where
- 10 sites in France
- Volunteers
- 170 people
- Sponsor
- Vascutek Ltd.
Familial Thoracic Aortic Aneurysm and Aortic Dissection
Application of Linkage Analysis in the Identification of Novel Hereditary Factors in Familial Aneurysms
The aim of this study is to describe the effectiveness of the application of Linkage Analysis, compared to the standard procedures currently provided by the italian NHS, in the identification of thoracic aortic aneurysms and…
- Trial name
- ORPHADIAG (NCT06783803)
- Testing
- Linkage Analysis
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Policlinico S. Donato
Abdominal Aortic Aneurysm (AAA), Thoracic Aortic Aneurysm (TAA)
Overlay of 3D Scans on Live Fluoroscopy for Endovascular Procedures in the Hybrid OR
As endovascular procedures become more complex, there is a growing need for 3D image overlay to assist with device guidance and placement.
- Conditions
- Abdominal Aortic Aneurysm (AAA), Thoracic Aortic Aneurysm (TAA), Carotid Stenosis, Visceral Artery Aneurysm
- Trial name
- NCT01480206
- Testing
- Endovascular Aortic Repair (EVAR)
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Thoracoabdominal Aneurysms
Visceral Manifold and Unitary Device Study for the Repair of Thoracoabdominal Aortic Aneurysms
The primary objective of the Visceral Manifold and Unitary Device Study is to assess the use of the thoracic bifurcation and the visceral manifold or the unitary device to repair thoracoabdominal aortic aneurysms in patients…
- Trial name
- NCT02294435
- Testing
- Visceral Manifold and Thoracic Bifurcation, Unitary Manifold
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Sanford Health
Thoracic Aortic Dissection, Thoracic Aortic Aneurysm (true Aneurysm)
Quick Yielding Modified Short-Distance Fenestration Technique for the Treatment of Complex Aortic Arch Diseases: a Multicenter Single-Arm Objective Performance Criteria Trial(QYM-Tech Study)
Background: This study investigates the safety and efficacy of a novel surgical approach combining thoracic endovascular aortic repair (TEVAR) and in situ fenestration reconstruction of supra-aortic branches using the Quick…
- Conditions
- Thoracic Aortic Dissection, Thoracic Aortic Aneurysm (true Aneurysm), Thoracic Pseudoaneurysm, Penetrating Aortic Ulcer
- Trial name
- NCT06639243
- Testing
- QYM Technique
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Thoracic Aortic Aneurysm, Thoracic Aorta Injury
CTAG Dissection/Trauma Post Marketing Surveillance Japan
Post Marketing Surveillance of the Conformable GORE® TAG® Thoracic Endoprosthesis
- Conditions
- Thoracic Aortic Aneurysm, Thoracic Aorta Injury, Thoracic Aortic Dissection
- Trial name
- NCT05414318
- Testing
- Conformable GORE® TAG® Thoracic Endoprosthesis
- Volunteers
- 55 people
- Sponsor
- W.L.Gore & Associates
Thoracic Aortic Dissection
Post-market Clinical Trial of the Dominus® Stent-Graft
Real-world clinical trial evidence post-market, evaluating the safety and efficacy of the Dominus® StentGraft Endoprosthesis in treating thoracic aortic diseases, following the Instructions for Use
- Trial name
- DominusPMCF (NCT06270537)
- Testing
- Stent-Graft Dominus® Endoprosthesis
- Where
- 3 sites in Brazil
- Volunteers
- 100 people
- Sponsor
- Braile Biomedica Ind. Com. e Repr. Ltda.
Aortic Diseases, Aortic Dissection
Proximal Aortopathy in Scotland - Epidemiology and Surgical Outcomes
The aorta is the principal arterial vessel arising from the left heart that transfers blood to the body. Certain genetic and familial disease processes are known to weaken the aortic wall resulting in dilation and potential…
- Conditions
- Aortic Diseases, Aortic Dissection, Aortic Aneurysm, Thoracic, Aortic Ectasia
- Trial name
- NCT05389865
- Testing
- Surgery on the proximal aorta (aortic root +/- ascending aorta), Patients diagnosed with thoracic aortopathy but not operated upon
- Where
- United Kingdom
- Volunteers
- 1,662 people
- Sponsor
- Golden Jubilee National Hospital
Thoracic Aortic Aneurysms
Biomechanical and Microstructural Properties of Ascending Aortic Aneurysms
An aortic aneurysm (thoracic or abdominal) is a permanent dilatation of the aorta caused by weakening in the arterial wall. The feared complication is aortic rupture or dissection, leading to potentially lethal aortic bleeding…
- Trial name
- NCT03142074
- Testing
- Biomechanical and microstructural analysis of ATAA, ECG-gated CT
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Systemic Inflammatory Response Syndrome, Infections
AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis
The goal of the prospective observational study is to evaluate the immunological background of inflammatory response often seen after open thoracic aortic surgery.
- Conditions
- Systemic Inflammatory Response Syndrome, Infections, Thoracic Aortic Aneurysm, Aortic Diseases
- Trial name
- AOSIS (NCT06028789)
- Testing
- Blood sample test, Thoracic Aortic Surgery
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Hradec Kralove
Aortic Aneurysm, Thoracic, Descending Thoracic Aortic Dissection
GORE® TAG® Thoracic Endoprosthesis French Mandatory Registry
This is a French Registry mandated by the French National Health Authority assessing long-term (5-years) safety of the GORE® TAG® Thoracic Endoprosthesis treating diseases of the thoracic aorta.
- Conditions
- Aortic Aneurysm, Thoracic, Descending Thoracic Aortic Dissection, Aortic Diseases, Aorta Thoracic; Traumatic Rupture
- Trial name
- NCT02266342
- Testing
- GORE® TAG® Thoracic Endoprostheses
- Where
- France
- Volunteers
- 154 people
- Sponsor
- W.L.Gore & Associates
Aortic Aneurysm, Thoracic
Valiant Evo International Clinical Trial
The purpose of the Valiant Evo International Clinical Trial is to demonstrate the safety and effectiveness of the Valiant Evo Thoracic Stent Graft System in subjects with a descending thoracic aortic aneurysm (DTAA) who are…
- Trial name
- NCT02625324
- Testing
- Valiant Evo Thoracic Stent Graft System
- Where
- 16 sites in Canada, Denmark and 4 more
- Volunteers
- 100 people
- Sponsor
- Medtronic Cardiovascular
Aortic Aneurysm, Thoracic
Valiant Evo US Clinical Trial
The purpose of the Valiant Evo US Clinical Trial is to demonstrate the safety and effectiveness of the Valiant Evo Thoracic Stent Graft System in subjects with a descending thoracic aortic aneurysm (DTAA) who are candidates for…
- Trial name
- VEVO (NCT02652949)
- Testing
- Valiant Evo Thoracic Stent Graft System
- Where
- 21 sites in United States
- Volunteers
- 100 people
- Sponsor
- Medtronic Cardiovascular
Aorta Abdominalis; Aneurysm, Aorta Thoracic; Aneurysm
Evaluation of the Efficacy and Safety of Surgical Device "Lymphoblock" for Prevention of Lymphorrhea in Patients With Thoracoabdominal Aorta Repair.
Randomized, double-blind, placebo-controlled study will determine the clinical efficacy and safety of Lymphoblock in the prevention of postoperative retroperitoneal chylo-/lymphorrhoea in patients with open surgical treatment of…
- Trial name
- NCT06286540
- Testing
- Lymphoblock
- Where
- Russia
- Volunteers
- 138 people
- Sponsor
- Petrovsky National Research Centre of Surgery
Aortic Aneurysm, Thoracic, Aortic Dissection
REgistRy BRAnch goRE EndopRosthEsis
Multicenter registry on patients treated by the new Gore thoracic branched endoprosthesis
- Trial name
- REBRA (NCT06276413)
- Testing
- GORE TAG Thoracic Branch Endoprosthesis
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University Hospital Padova
Bicuspid Aortic Valve, Thoracic Aortic Aneurysm
Assessment of Risk in Thoracic Aortopathy Using 18F-Sodium Fluoride
Patients with bicuspid aortic valve-related aortopathy are at increased risk of aortic dilatation, dissection and rupture. Currently, risk stratification is largely based on aortic diameter measurements, with those deemed high…
- Conditions
- Bicuspid Aortic Valve, Thoracic Aortic Aneurysm, Aortic Dissection
- Trial name
- AoRTAS (NCT04083118)
- Testing
- clinical evaluation, blood markers, pulse wave analysis, 18F sodium fluoride PET/CT and PET/MRI, Repeat 18F sodium fluoride PET/MRI
- Where
- United Kingdom
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Aortic Aneurysm, Thoracic
VALIANT CAPTIVIA Post-market Registry
The Valiant Thoracic Stent Graft has been preloaded on the new Captivia Delivery System (Captivia). This new delivery system was CE marked on September 14th, 2009 and was commercially released in the European Union on October…
- Trial name
- VCOUS (NCT01181947)
- Testing
- TEVAR
- Where
- 15 sites in Austria, Germany and 5 more
- Volunteers
- 100 people
- Sponsor
- Medtronic Cardiovascular
Thoracic Aortic Arch Disease, Thoracic Aortic Aneurysm
NEXUS™ Aortic Arch Stent Graft System First In Man Study
A multicenter, prospective, open-label, non-randomized, interventional clinical study, sponsored by Endospan Ltd. Patients will be followed-up for five years.
- Trial name
- NCT02365454
- Testing
- Stent Graft Placement (Nexus)
- Where
- 4 sites in Czechia, Italy and 1 more
- Volunteers
- 18 people
- Sponsor
- Endospan Ltd.
Thoracic Aortic Aneurysm
Intravascular Ultrasound (IVUS) in Complex Aortic Endovascular Interventions
The study aims to investigate the applicability of intravascular ultrasound (IVUS) in the endovascular therapy of juxta-, supra- and thoracoabdominal aortic aneurysms.
- Trial name
- NCT04663074
- Testing
- IVUS control
- Where
- 6 sites in Denmark, Germany and 2 more
- Volunteers
- 80 people
- Sponsor
- University Hospital Muenster
Thoracic Aortic Aneurysms, Thoracic Transections
Physician-Sponsored IDE for the Talent Endoluminal Stent Graft System for the Treatment of Thoracic Lesions
The primary objective of this trial is to determine whether the Talent Thoracic Stent Graft, an investigational device, is a safe and effective method of treating thoracic aortic aneurysms (abnormal ballooning of the vessel wall)…
- Conditions
- Thoracic Aortic Aneurysms, Thoracic Transections, Intramural Hematoma, Pseudoaneurysm
- Trial name
- NCT00597870
- Testing
- Endoluminal treament of thoracic lesions
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- Rodney A. White, M.D.